| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is acr1 [H]
Identifier: 41409594
GI number: 41409594
Start: 3888800
End: 3889738
Strand: Direct
Name: acr1 [H]
Synonym: MAP3496
Alternate gene names: 41409594
Gene position: 3888800-3889738 (Clockwise)
Preceding gene: 41409592
Following gene: 41409595
Centisome position: 80.52
GC content: 73.16
Gene sequence:
>939_bases GTGGTTCAGGCGGCTCGAACGAATGCGGCGGCGAAGGTGAACGCAATAGCGCAGGCCCTCGACAAGGTCCTCAACACGGT GGCCGACCGGGTGGCCAACCCGGCGCGGGTGTCGGACCCGGACCGGTTGCGCGGCGCCGTCGGCGGCAGGACGGTCCTGG TGACCGGCGCCTCCTACGGCATCGGCGAGGCGACCGCGCGCCGCCTGGCCGCCGCCGGCGCGACGGTGCTGGTGGTCGCC CGCTCCGAGGAGCGGCTCGGCGAGCTGACGGCGGCGATCAACGCCGGCGGCGGGCGGGCGGTCGCCTACCCGACCGACCT CACCGACGAATCCGCGGTCAGCGCCCTGACCAAACAGATCACCGAGGAACACGGCCCGCTCGACGTCGTGGTGAGCAACG CCGGCAAGTCGCTGCGCCGCTCGCTGCATCACCAGTACGACCGGCCGCACGACTTCCAGCGCACCATCGACGTCAACTAC CTGGGGCCGGTCCGGTTGCTGCTCGGGCTGTTACCGGCCATGCGCGACAACGGCCGCGGGCACGTCGTGAACGTGTCCAG CGTCGGGGTGCGGGTGGTGCCGGGTCCGCAGTGGGGCGCCTACCAGGCGTCCAAGGGAGCCTTCGACCGGTGGCTGCGCA GCGTGGCCCCCGAATTGCACGCCGACGGCGTGCACGTCAGCACGGTCTACTTCGCGTTGGTCCGGACCCGGATGATCGCG CCCACACCGGTTTTAGGCCGGCTGCCCGGCCTGTCGCCGGACCAGGCGGCCGACGTCATCGCCAAGGCCGTCATCGAGCG GCCGCGCACCCTCGAGCCGCCCTGGGTGCTGCCGGCCGAGCTGGCCTCGGTGCTGCTGGCCGGCCCGGCCGACCGCGCCG CACGGCTGTGGCATCGCCGGTTCTTCAGCGACGCCGAGGAGGCCGGCCGTGAGCGCTGA
Upstream 100 bases:
>100_bases CGGCGGGTGTGCCCATCCCCGGGCGCGGGTGCGCCGCACCGGCATTCGGCGAACATCCGGGCCGGGGCACGACGGCCGGC CGGGATGTGGTCTGCTACTT
Downstream 100 bases:
>100_bases ACGGGTGGCGCCCACCGCCGCCCGGGCGCTGGTGCGCTCCGGTCTGCTCAACCCGCCCTCGCCGCGGGCGGTTCTGCGGC TGCTTCGCGAGGCGAGCCGC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 312; Mature: 312
Protein sequence:
>312_residues MVQAARTNAAAKVNAIAQALDKVLNTVADRVANPARVSDPDRLRGAVGGRTVLVTGASYGIGEATARRLAAAGATVLVVA RSEERLGELTAAINAGGGRAVAYPTDLTDESAVSALTKQITEEHGPLDVVVSNAGKSLRRSLHHQYDRPHDFQRTIDVNY LGPVRLLLGLLPAMRDNGRGHVVNVSSVGVRVVPGPQWGAYQASKGAFDRWLRSVAPELHADGVHVSTVYFALVRTRMIA PTPVLGRLPGLSPDQAADVIAKAVIERPRTLEPPWVLPAELASVLLAGPADRAARLWHRRFFSDAEEAGRER
Sequences:
>Translated_312_residues MVQAARTNAAAKVNAIAQALDKVLNTVADRVANPARVSDPDRLRGAVGGRTVLVTGASYGIGEATARRLAAAGATVLVVA RSEERLGELTAAINAGGGRAVAYPTDLTDESAVSALTKQITEEHGPLDVVVSNAGKSLRRSLHHQYDRPHDFQRTIDVNY LGPVRLLLGLLPAMRDNGRGHVVNVSSVGVRVVPGPQWGAYQASKGAFDRWLRSVAPELHADGVHVSTVYFALVRTRMIA PTPVLGRLPGLSPDQAADVIAKAVIERPRTLEPPWVLPAELASVLLAGPADRAARLWHRRFFSDAEEAGRER >Mature_312_residues MVQAARTNAAAKVNAIAQALDKVLNTVADRVANPARVSDPDRLRGAVGGRTVLVTGASYGIGEATARRLAAAGATVLVVA RSEERLGELTAAINAGGGRAVAYPTDLTDESAVSALTKQITEEHGPLDVVVSNAGKSLRRSLHHQYDRPHDFQRTIDVNY LGPVRLLLGLLPAMRDNGRGHVVNVSSVGVRVVPGPQWGAYQASKGAFDRWLRSVAPELHADGVHVSTVYFALVRTRMIA PTPVLGRLPGLSPDQAADVIAKAVIERPRTLEPPWVLPAELASVLLAGPADRAARLWHRRFFSDAEEAGRER
Specific function: Catalyzes the NADPH-dependent reduction of long chain acyl-CoA to the corresponding aldehyde [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=194, Percent_Identity=33.5051546391753, Blast_Score=88, Evalue=1e-17, Organism=Homo sapiens, GI32455239, Length=189, Percent_Identity=32.8042328042328, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI5031765, Length=189, Percent_Identity=32.8042328042328, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI142976729, Length=239, Percent_Identity=27.6150627615063, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI40807363, Length=243, Percent_Identity=29.6296296296296, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI7706318, Length=184, Percent_Identity=33.695652173913, Blast_Score=78, Evalue=8e-15, Organism=Homo sapiens, GI210032110, Length=242, Percent_Identity=27.6859504132231, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI157739938, Length=206, Percent_Identity=26.2135922330097, Blast_Score=73, Evalue=4e-13, Organism=Homo sapiens, GI226371731, Length=208, Percent_Identity=28.8461538461538, Blast_Score=72, Evalue=5e-13, Organism=Homo sapiens, GI40254986, Length=247, Percent_Identity=27.1255060728745, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI109715829, Length=250, Percent_Identity=28.8, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI32483357, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI223718074, Length=213, Percent_Identity=32.8638497652582, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI126723191, Length=193, Percent_Identity=28.4974093264249, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI4557649, Length=184, Percent_Identity=26.6304347826087, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI166795268, Length=212, Percent_Identity=29.2452830188679, Blast_Score=66, Evalue=5e-11, Organism=Homo sapiens, GI33667109, Length=197, Percent_Identity=30.9644670050761, Blast_Score=65, Evalue=1e-10, Organism=Escherichia coli, GI87082100, Length=194, Percent_Identity=33.5051546391753, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=28.9617486338798, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI1787335, Length=214, Percent_Identity=29.4392523364486, Blast_Score=74, Evalue=2e-14, Organism=Escherichia coli, GI2367175, Length=202, Percent_Identity=32.1782178217822, Blast_Score=73, Evalue=3e-14, Organism=Escherichia coli, GI1787905, Length=151, Percent_Identity=31.1258278145695, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786701, Length=245, Percent_Identity=30.2040816326531, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1790717, Length=199, Percent_Identity=26.6331658291457, Blast_Score=64, Evalue=1e-11, Organism=Escherichia coli, GI87082160, Length=227, Percent_Identity=27.3127753303965, Blast_Score=63, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17538480, Length=199, Percent_Identity=33.1658291457286, Blast_Score=92, Evalue=4e-19, Organism=Caenorhabditis elegans, GI17508895, Length=232, Percent_Identity=26.2931034482759, Blast_Score=86, Evalue=4e-17, Organism=Caenorhabditis elegans, GI17560332, Length=190, Percent_Identity=30.5263157894737, Blast_Score=85, Evalue=5e-17, Organism=Caenorhabditis elegans, GI193204405, Length=192, Percent_Identity=32.2916666666667, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI17544670, Length=219, Percent_Identity=29.6803652968037, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562906, Length=190, Percent_Identity=32.6315789473684, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17562904, Length=217, Percent_Identity=30.4147465437788, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17560150, Length=247, Percent_Identity=27.5303643724696, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17551412, Length=194, Percent_Identity=29.8969072164948, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17567345, Length=241, Percent_Identity=25.7261410788382, Blast_Score=77, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17565030, Length=252, Percent_Identity=29.3650793650794, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17564282, Length=278, Percent_Identity=25.5395683453237, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI193203115, Length=239, Percent_Identity=29.2887029288703, Blast_Score=74, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17531453, Length=196, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17562990, Length=188, Percent_Identity=28.7234042553192, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI72000259, Length=189, Percent_Identity=30.1587301587302, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193203117, Length=226, Percent_Identity=29.2035398230088, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17538486, Length=192, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17563726, Length=202, Percent_Identity=26.7326732673267, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17538182, Length=205, Percent_Identity=30.7317073170732, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17558006, Length=201, Percent_Identity=29.8507462686567, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17559104, Length=192, Percent_Identity=27.6041666666667, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17562908, Length=190, Percent_Identity=30.5263157894737, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560220, Length=249, Percent_Identity=27.3092369477912, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI71982365, Length=150, Percent_Identity=32.6666666666667, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI115534694, Length=221, Percent_Identity=31.2217194570136, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI71997402, Length=236, Percent_Identity=28.3898305084746, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562910, Length=203, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560676, Length=192, Percent_Identity=29.1666666666667, Blast_Score=67, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=33.1632653061224, Blast_Score=86, Evalue=8e-18, Organism=Saccharomyces cerevisiae, GI6320089, Length=235, Percent_Identity=26.3829787234043, Blast_Score=74, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=28.1124497991968, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322226, Length=172, Percent_Identity=30.8139534883721, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI21357041, Length=195, Percent_Identity=34.3589743589744, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=182, Percent_Identity=35.1648351648352, Blast_Score=89, Evalue=5e-18, Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=33.495145631068, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI21358495, Length=266, Percent_Identity=27.8195488721804, Blast_Score=86, Evalue=4e-17, Organism=Drosophila melanogaster, GI24640492, Length=232, Percent_Identity=27.1551724137931, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI24649181, Length=273, Percent_Identity=27.1062271062271, Blast_Score=81, Evalue=7e-16, Organism=Drosophila melanogaster, GI24644339, Length=187, Percent_Identity=34.2245989304813, Blast_Score=81, Evalue=8e-16, Organism=Drosophila melanogaster, GI24643142, Length=192, Percent_Identity=33.3333333333333, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24663911, Length=228, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI281364892, Length=233, Percent_Identity=27.0386266094421, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI24581726, Length=257, Percent_Identity=28.4046692607004, Blast_Score=73, Evalue=2e-13, Organism=Drosophila melanogaster, GI23397609, Length=192, Percent_Identity=33.8541666666667, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24648944, Length=224, Percent_Identity=30.8035714285714, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24641388, Length=231, Percent_Identity=29.8701298701299, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=27.363184079602, Blast_Score=66, Evalue=3e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 33285; Mature: 33285
Theoretical pI: Translated: 10.41; Mature: 10.41
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.0 %Met (Translated Protein) 1.0 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.0 %Met (Mature Protein) 1.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVQAARTNAAAKVNAIAQALDKVLNTVADRVANPARVSDPDRLRGAVGGRTVLVTGASYG CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCC IGEATARRLAAAGATVLVVARSEERLGELTAAINAGGGRAVAYPTDLTDESAVSALTKQI CCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH TEEHGPLDVVVSNAGKSLRRSLHHQYDRPHDFQRTIDVNYLGPVRLLLGLLPAMRDNGRG HHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHEECCCCCCHHHHHHHHHHHHHCCCCC HVVNVSSVGVRVVPGPQWGAYQASKGAFDRWLRSVAPELHADGVHVSTVYFALVRTRMIA EEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHCC PTPVLGRLPGLSPDQAADVIAKAVIERPRTLEPPWVLPAELASVLLAGPADRAARLWHRR CCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH FFSDAEEAGRER HHHHHHHCCCCC >Mature Secondary Structure MVQAARTNAAAKVNAIAQALDKVLNTVADRVANPARVSDPDRLRGAVGGRTVLVTGASYG CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEEEECCCCC IGEATARRLAAAGATVLVVARSEERLGELTAAINAGGGRAVAYPTDLTDESAVSALTKQI CCHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHH TEEHGPLDVVVSNAGKSLRRSLHHQYDRPHDFQRTIDVNYLGPVRLLLGLLPAMRDNGRG HHHCCCEEEEECCCCHHHHHHHHHHCCCCCCHHHEECCCCCCHHHHHHHHHHHHHCCCCC HVVNVSSVGVRVVPGPQWGAYQASKGAFDRWLRSVAPELHADGVHVSTVYFALVRTRMIA EEEEECCCCEEEECCCCCCCCCCCCHHHHHHHHHHCHHHHCCCCHHHHHHHHHHHHHHCC PTPVLGRLPGLSPDQAADVIAKAVIERPRTLEPPWVLPAELASVLLAGPADRAARLWHRR CCCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHH FFSDAEEAGRER HHHHHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA