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The map label for this gene is namA [H]

Identifier: 41409562

GI number: 41409562

Start: 3845617

End: 3846834

Strand: Direct

Name: namA [H]

Synonym: MAP3464

Alternate gene names: 41409562

Gene position: 3845617-3846834 (Clockwise)

Preceding gene: 41409559

Following gene: 41409563

Centisome position: 79.62

GC content: 69.05

Gene sequence:

>1218_bases
ATGCCCACCCCTCCGGACGTGTTCAGCCCCGCCAAGCTCGGTCCGATCACGCTGCGCAATCGCATCATCAAGTCCGCCAC
CTTCGAGGCGCGTACACCGGACGCGCTGGTGACCGACGACCTCATCGAATACCACCGGCTGCCCGCCGTGGGCGGCGTCG
GCATGACGACCGTCGCCTACTGCGCGGTCTCCCCCGGCGGCCGCACCGAGGGCAACGGCATCTGGATGCGGCCCGAGGCC
GTGCCCGGGTTCCGCCGGCTCACCGACGCGATCCACGCCGAGGGCGCGGCGGTCAGCGCGCAGATCGGGCACGCCGGGCC
GGTGGCCAACGCCAGGTCCAACAAGGCGCAGGCGCTGGCGCCGGTCCGGTTCTTCAACCCGATCGGAATGCGGTTCGCCA
AGAAGGCGACCCGCGACGACATCGACGAGGTGATCGCCGCGCACGCCAACGCCGCGCGGCTGGCCATCGAGGCCGGGTTC
GACGCCGTCGAAATCCACCTGGGCCACAACTATTTGGCGAGTTCGTTCCTGTCCCCGCTGATCAACCGGCGCAACGACGA
GTTCGGCGGGTCGCTGCAGAACCGTGCGAAGGTGGCCCGCGGCATGGTGATGGCCGTGCGGCGGGCGGTGGAAAAGGAGG
GCACGCCCATCGCGGTGACGGCCAAGCTGAACATGGCCGACGGGGTGCGCGGCGGCATCAGCACCGAGGAATCGCTGACC
ACCGCCAAGTGGCTGGAGTCCGACGGCGGCCTGGACGCGATCGAGCTCACCGCGGGCAGCTCGCTGGTCAACCCGATGTA
CCTGTTCCGGGGCGACGCGCCGCTCAAGGAGTTCGCCGGCGCGTTCAAGCCGCCGCTGCGCTGGGGCATGCGCATGACGG
GCAAGAAGTTCCTGCGCGAATACCCCTACCGCGACGCGTATCTATTGCGGGACGCCAAGCTGTTTCGCGCCGAGCTGAAG
ATGCCGCTGATCCTGCTGGGCGGCATCACCAATCGGGAGACGATGGACCTGGCGATGGCGGAGGGGTTCGAGTTCGTTGC
CATGGCCCGCGCGCTGCTGGCCGAGCCGGATCTGATCAACCGGATCGCCGCCGACGGTGCCGCGCACCGGGTGCATTCGG
CGTGCACGCACTGCAATCAGTGCATGCCCACCATCTACAGCCGAACGCACTGCGTGGTCACCGGTGCGCCCGACCGGCAC
ACCAGCGCCGCAACTTAA

Upstream 100 bases:

>100_bases
GCGGCGACCCGCTGCTTGAGGTCGACGAAGATTTCGTCGCGGGTGGCCTTGCCGTCCAGTGTGATTGCTCCCACGCTGAC
AGTCTGGCACGCTCCCCGAT

Downstream 100 bases:

>100_bases
TCCACAGCGCTGCAAGCTACAGTTGTGGCGATGTCAGCACCAGCCCCGCCAGCGCTAACCGTCCATCACGAAGGCTCGGA
ACGTACCTTCGCCGCGGGCC

Product: hypothetical protein

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPTPPDVFSPAKLGPITLRNRIIKSATFEARTPDALVTDDLIEYHRLPAVGGVGMTTVAYCAVSPGGRTEGNGIWMRPEA
VPGFRRLTDAIHAEGAAVSAQIGHAGPVANARSNKAQALAPVRFFNPIGMRFAKKATRDDIDEVIAAHANAARLAIEAGF
DAVEIHLGHNYLASSFLSPLINRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTPIAVTAKLNMADGVRGGISTEESLT
TAKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPLKEFAGAFKPPLRWGMRMTGKKFLREYPYRDAYLLRDAKLFRAELK
MPLILLGGITNRETMDLAMAEGFEFVAMARALLAEPDLINRIAADGAAHRVHSACTHCNQCMPTIYSRTHCVVTGAPDRH
TSAAT

Sequences:

>Translated_405_residues
MPTPPDVFSPAKLGPITLRNRIIKSATFEARTPDALVTDDLIEYHRLPAVGGVGMTTVAYCAVSPGGRTEGNGIWMRPEA
VPGFRRLTDAIHAEGAAVSAQIGHAGPVANARSNKAQALAPVRFFNPIGMRFAKKATRDDIDEVIAAHANAARLAIEAGF
DAVEIHLGHNYLASSFLSPLINRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTPIAVTAKLNMADGVRGGISTEESLT
TAKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPLKEFAGAFKPPLRWGMRMTGKKFLREYPYRDAYLLRDAKLFRAELK
MPLILLGGITNRETMDLAMAEGFEFVAMARALLAEPDLINRIAADGAAHRVHSACTHCNQCMPTIYSRTHCVVTGAPDRH
TSAAT
>Mature_404_residues
PTPPDVFSPAKLGPITLRNRIIKSATFEARTPDALVTDDLIEYHRLPAVGGVGMTTVAYCAVSPGGRTEGNGIWMRPEAV
PGFRRLTDAIHAEGAAVSAQIGHAGPVANARSNKAQALAPVRFFNPIGMRFAKKATRDDIDEVIAAHANAARLAIEAGFD
AVEIHLGHNYLASSFLSPLINRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTPIAVTAKLNMADGVRGGISTEESLTT
AKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPLKEFAGAFKPPLRWGMRMTGKKFLREYPYRDAYLLRDAKLFRAELKM
PLILLGGITNRETMDLAMAEGFEFVAMARALLAEPDLINRIAADGAAHRVHSACTHCNQCMPTIYSRTHCVVTGAPDRHT
SAAT

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=404, Percent_Identity=26.7326732673267, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787939, Length=382, Percent_Identity=27.7486910994764, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17566914, Length=257, Percent_Identity=33.852140077821, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=400, Percent_Identity=25.25, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559802, Length=400, Percent_Identity=24.25, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=369, Percent_Identity=26.0162601626016, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17559804, Length=381, Percent_Identity=25.1968503937008, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17540738, Length=268, Percent_Identity=28.7313432835821, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI72001454, Length=371, Percent_Identity=24.2587601078167, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6321973, Length=248, Percent_Identity=30.241935483871, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=253, Percent_Identity=28.4584980237154, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 43720; Mature: 43589

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPPDVFSPAKLGPITLRNRIIKSATFEARTPDALVTDDLIEYHRLPAVGGVGMTTVAY
CCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
CAVSPGGRTEGNGIWMRPEAVPGFRRLTDAIHAEGAAVSAQIGHAGPVANARSNKAQALA
EEECCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHCC
PVRFFNPIGMRFAKKATRDDIDEVIAAHANAARLAIEAGFDAVEIHLGHNYLASSFLSPL
CHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCEEEEEECCHHHHHHHHHHH
INRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTPIAVTAKLNMADGVRGGISTEESLT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHH
TAKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPLKEFAGAFKPPLRWGMRMTGKKFLRE
HHHHHHCCCCCCEEEEECCCCHHCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
YPYRDAYLLRDAKLFRAELKMPLILLGGITNRETMDLAMAEGFEFVAMARALLAEPDLIN
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHH
RIAADGAAHRVHSACTHCNQCMPTIYSRTHCVVTGAPDRHTSAAT
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
PTPPDVFSPAKLGPITLRNRIIKSATFEARTPDALVTDDLIEYHRLPAVGGVGMTTVAY
CCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
CAVSPGGRTEGNGIWMRPEAVPGFRRLTDAIHAEGAAVSAQIGHAGPVANARSNKAQALA
EEECCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHCC
PVRFFNPIGMRFAKKATRDDIDEVIAAHANAARLAIEAGFDAVEIHLGHNYLASSFLSPL
CHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCEEEEEECCHHHHHHHHHHH
INRRNDEFGGSLQNRAKVARGMVMAVRRAVEKEGTPIAVTAKLNMADGVRGGISTEESLT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHH
TAKWLESDGGLDAIELTAGSSLVNPMYLFRGDAPLKEFAGAFKPPLRWGMRMTGKKFLRE
HHHHHHCCCCCCEEEEECCCCHHCCEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHH
YPYRDAYLLRDAKLFRAELKMPLILLGGITNRETMDLAMAEGFEFVAMARALLAEPDLIN
CCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHH
RIAADGAAHRVHSACTHCNQCMPTIYSRTHCVVTGAPDRHTSAAT
HHHHCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]