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The map label for this gene is trpS

Identifier: 41409551

GI number: 41409551

Start: 3832919

End: 3833950

Strand: Reverse

Name: trpS

Synonym: MAP3453c

Alternate gene names: 41409551

Gene position: 3833950-3832919 (Counterclockwise)

Preceding gene: 41409553

Following gene: 41409550

Centisome position: 79.38

GC content: 68.02

Gene sequence:

>1032_bases
ATGAGCACCGCCACCGGATCCCGCCGGATTTTCTCCGGCGTCCAGCCCACGTCCGATTCGCTGCACCTGGGCAACGCGTT
GGGCGCCATCTCGCAGTGGGTGACCCTGCAGGACGACTGGGGCGACGACTGGGACGCGTTCTTCTGCGTGGTCGACCTGC
ACGCCATCACCATCGCCCAGGACCCCGCGGCGCTGCGCCGGCGGACCCTGGTCACCGCCGCCCAGTACCTGGCGCTGGGC
ATCGACCCGGCCCGCAGCACCGTGTTCGTGCAAAGCCACGTGCCCGCCCACACCCAGCTGGCCTGGGTGCTGGGCTGCTT
CACCGGCTTCGGCCAGGCCTCGCGGATGACGCAGTTCAAGGACAAGTCGCTGCGCCAGGGCGCGGACTCCACCACGGTGG
GCCTGTTCACCTATCCGGTGCTGCAGGCCGCCGACGTGCTGGCCTACGACACCGGCCTGGTGCCCGTCGGCGAGGACCAG
CGCCAGCACCTGGAGTTGGCGCGCGACGTGGCGCAGCGGTTCAACGCCCGCTTCCCGGACACGTTCGTGGTGCCGGAGAT
GCTCATCCCCAAGGTCACCGCCAAGATCTACGACTTGGCCGACCCGACGTCGAAGATGAGCAAGTCGGCGTCCACCGATG
CCGGGCTGATCAACCTGCTCGACGATCCGGCGTTGTCCGCCAAGAAGATTCGCTCCGCGGTCACCGACAGCGAGCGGGAG
ATCCGGTTCGACACCGACGCCAAGCCGGGAGTGTCCAACCTGCTGAGCATCCAGTCCGCGGTCAGCGGCGTCGACATCGA
CAAGCTCGTGCAGGGCTACGCCGGAAGGGGTTACGGCGATCTGAAGAAGGACACCGCGGACGCGGTGGTCGAGTTCGTCA
CCCCGATCAAGGCCCGCGTCGACGAATTGATGGCCGACCCGGCCGAATTGGAGGCCGTTCTGGCGGCCGGGGCGCAACGG
GCCCAGGATGTCGCCGGGAAAACCGTCGAACGGGTTTACGATCGGCTTGGGTTCCTTCCGCGACGGGGGTAA

Upstream 100 bases:

>100_bases
CGGTACCGCCGGTACCGCAAGTTTGGTGGGCGGCGCGGGCAGCGGTCCGTGCGGGCCGCGGCACGGCGCGGGAGACGAGG
CGTGAAAAGATCGGTGCATC

Downstream 100 bases:

>100_bases
GAAGTTCCACGATGAGCGAGCCGGCCGAGGCGGGGTTTCTTGATCGGCTGCGGGCCCGGCACGGCTGGCTGGATCACCTC
ATCCGCGCCTACCAGCGATT

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MSTATGSRRIFSGVQPTSDSLHLGNALGAISQWVTLQDDWGDDWDAFFCVVDLHAITIAQDPAALRRRTLVTAAQYLALG
IDPARSTVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFKDKSLRQGADSTTVGLFTYPVLQAADVLAYDTGLVPVGEDQ
RQHLELARDVAQRFNARFPDTFVVPEMLIPKVTAKIYDLADPTSKMSKSASTDAGLINLLDDPALSAKKIRSAVTDSERE
IRFDTDAKPGVSNLLSIQSAVSGVDIDKLVQGYAGRGYGDLKKDTADAVVEFVTPIKARVDELMADPAELEAVLAAGAQR
AQDVAGKTVERVYDRLGFLPRRG

Sequences:

>Translated_343_residues
MSTATGSRRIFSGVQPTSDSLHLGNALGAISQWVTLQDDWGDDWDAFFCVVDLHAITIAQDPAALRRRTLVTAAQYLALG
IDPARSTVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFKDKSLRQGADSTTVGLFTYPVLQAADVLAYDTGLVPVGEDQ
RQHLELARDVAQRFNARFPDTFVVPEMLIPKVTAKIYDLADPTSKMSKSASTDAGLINLLDDPALSAKKIRSAVTDSERE
IRFDTDAKPGVSNLLSIQSAVSGVDIDKLVQGYAGRGYGDLKKDTADAVVEFVTPIKARVDELMADPAELEAVLAAGAQR
AQDVAGKTVERVYDRLGFLPRRG
>Mature_342_residues
STATGSRRIFSGVQPTSDSLHLGNALGAISQWVTLQDDWGDDWDAFFCVVDLHAITIAQDPAALRRRTLVTAAQYLALGI
DPARSTVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFKDKSLRQGADSTTVGLFTYPVLQAADVLAYDTGLVPVGEDQR
QHLELARDVAQRFNARFPDTFVVPEMLIPKVTAKIYDLADPTSKMSKSASTDAGLINLLDDPALSAKKIRSAVTDSEREI
RFDTDAKPGVSNLLSIQSAVSGVDIDKLVQGYAGRGYGDLKKDTADAVVEFVTPIKARVDELMADPAELEAVLAAGAQRA
QDVAGKTVERVYDRLGFLPRRG

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=334, Percent_Identity=42.814371257485, Blast_Score=276, Evalue=1e-74,
Organism=Homo sapiens, GI41352700, Length=182, Percent_Identity=50.5494505494505, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1789786, Length=334, Percent_Identity=51.1976047904192, Blast_Score=339, Evalue=2e-94,
Organism=Caenorhabditis elegans, GI71982800, Length=341, Percent_Identity=35.4838709677419, Blast_Score=207, Evalue=5e-54,
Organism=Caenorhabditis elegans, GI71982793, Length=341, Percent_Identity=35.4838709677419, Blast_Score=207, Evalue=9e-54,
Organism=Saccharomyces cerevisiae, GI6320474, Length=344, Percent_Identity=35.1744186046512, Blast_Score=213, Evalue=5e-56,
Organism=Drosophila melanogaster, GI24666151, Length=332, Percent_Identity=40.6626506024096, Blast_Score=249, Evalue=3e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37099; Mature: 36968

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTATGSRRIFSGVQPTSDSLHLGNALGAISQWVTLQDDWGDDWDAFFCVVDLHAITIAQ
CCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHEEEC
DPAALRRRTLVTAAQYLALGIDPARSTVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFK
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHH
DKSLRQGADSTTVGLFTYPVLQAADVLAYDTGLVPVGEDQRQHLELARDVAQRFNARFPD
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
TFVVPEMLIPKVTAKIYDLADPTSKMSKSASTDAGLINLLDDPALSAKKIRSAVTDSERE
CCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCC
IRFDTDAKPGVSNLLSIQSAVSGVDIDKLVQGYAGRGYGDLKKDTADAVVEFVTPIKARV
EEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DELMADPAELEAVLAAGAQRAQDVAGKTVERVYDRLGFLPRRG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
STATGSRRIFSGVQPTSDSLHLGNALGAISQWVTLQDDWGDDWDAFFCVVDLHAITIAQ
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHEEEC
DPAALRRRTLVTAAQYLALGIDPARSTVFVQSHVPAHTQLAWVLGCFTGFGQASRMTQFK
CHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHH
DKSLRQGADSTTVGLFTYPVLQAADVLAYDTGLVPVGEDQRQHLELARDVAQRFNARFPD
HHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
TFVVPEMLIPKVTAKIYDLADPTSKMSKSASTDAGLINLLDDPALSAKKIRSAVTDSERE
CCCCHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCCC
IRFDTDAKPGVSNLLSIQSAVSGVDIDKLVQGYAGRGYGDLKKDTADAVVEFVTPIKARV
EEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHH
DELMADPAELEAVLAAGAQRAQDVAGKTVERVYDRLGFLPRRG
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]