Click here to switch to the map view.

The map label for this gene is sugE

Identifier: 41409549

GI number: 41409549

Start: 3831493

End: 3831882

Strand: Direct

Name: sugE

Synonym: MAP3451

Alternate gene names: 41409549

Gene position: 3831493-3831882 (Clockwise)

Preceding gene: 41409548

Following gene: 41409552

Centisome position: 79.33

GC content: 70.0

Gene sequence:

>390_bases
GTGCCGTCAGCAACTGACACCGGACGAGGGGCCCCGTACCCGGCCAGCGACAAGACGGCGCCGTGGAGGTGCGCAATGGC
CTGGCTGATCCTGATCGCCTCGGGTGTGCTGGAAGCGGTGTGGGCGACCGCGCTGAGCCGGTCCGAGGGTTTTTCCCGGC
TCGGCCCGTCGCTGGTTTTCTTTGTGGCGCTGGCATTTTCGATGACCGGGCTGGCGGTCGCGATGCGCAGCCTGCCGGTC
GGCACCAGCTACGCGGTCTGGGTGGGCGTCGGCGCCGCGCTCACGGTGACCTATGCGGCGCTGGTCGGCGACGAACCGGC
GTCGCCGGTCAAGCTGGTGCTGATCGCCGGGATCGTGGCCTGCGTCGCGGGACTGAAGCTGCTCGGCTAG

Upstream 100 bases:

>100_bases
CCTGAGGCCAATCTTGTTGTGCTGGACGCTGATTGGCGGGTTAGGGCCGTCATAGCCCGCGGCGACTGGCTGGCCGACGC
GTAGCGATCTTGTAACATCG

Downstream 100 bases:

>100_bases
CGGCGCCGGCGGGTGAGCCGGTCGAACGCCAGCGCCGCAACGGCTCCCAGGCCCATCGCGGTCAGCGTCTGGCGGGTGTT
CAGCCCCTCGTCCAGGTGCA

Product: SugE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MPSATDTGRGAPYPASDKTAPWRCAMAWLILIASGVLEAVWATALSRSEGFSRLGPSLVFFVALAFSMTGLAVAMRSLPV
GTSYAVWVGVGAALTVTYAALVGDEPASPVKLVLIAGIVACVAGLKLLG

Sequences:

>Translated_129_residues
MPSATDTGRGAPYPASDKTAPWRCAMAWLILIASGVLEAVWATALSRSEGFSRLGPSLVFFVALAFSMTGLAVAMRSLPV
GTSYAVWVGVGAALTVTYAALVGDEPASPVKLVLIAGIVACVAGLKLLG
>Mature_128_residues
PSATDTGRGAPYPASDKTAPWRCAMAWLILIASGVLEAVWATALSRSEGFSRLGPSLVFFVALAFSMTGLAVAMRSLPVG
TSYAVWVGVGAALTVTYAALVGDEPASPVKLVLIAGIVACVAGLKLLG

Specific function: Quaternary ammonium compound efflux pump. Confers resistance to cetylpyridinium, cetyldimethylethyl ammonium and cetrimide cations [H]

COG id: COG2076

COG function: function code P; Membrane transporters of cations and cationic drugs

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the small multidrug resistance (SMR) protein family. SugE (TC 2.A.7.1.4) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082378, Length=102, Percent_Identity=48.0392156862745, Blast_Score=89, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000390 [H]

Pfam domain/function: PF00893 Multi_Drug_Res [H]

EC number: NA

Molecular weight: Translated: 13141; Mature: 13009

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSATDTGRGAPYPASDKTAPWRCAMAWLILIASGVLEAVWATALSRSEGFSRLGPSLVF
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FVALAFSMTGLAVAMRSLPVGTSYAVWVGVGAALTVTYAALVGDEPASPVKLVLIAGIVA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CVAGLKLLG
HHHHHHHCC
>Mature Secondary Structure 
PSATDTGRGAPYPASDKTAPWRCAMAWLILIASGVLEAVWATALSRSEGFSRLGPSLVF
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
FVALAFSMTGLAVAMRSLPVGTSYAVWVGVGAALTVTYAALVGDEPASPVKLVLIAGIVA
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
CVAGLKLLG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12644504; 11677608 [H]