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The map label for this gene is lat

Identifier: 41409508

GI number: 41409508

Start: 3784213

End: 3785553

Strand: Reverse

Name: lat

Synonym: MAP3410c

Alternate gene names: 41409508

Gene position: 3785553-3784213 (Counterclockwise)

Preceding gene: 41409509

Following gene: 41409507

Centisome position: 78.38

GC content: 71.96

Gene sequence:

>1341_bases
ATGACCGCCGCACTGGAACGCCTGGCCCGCGCCCGCTCCTGCACCGGCCCCGACCGGGTGCACGAGGTGTTGTCGCGCAG
CATCCTGACCGACGGTTTCGACTTCGTGCTGGACCTGGACCGCTCCCGCGGATCGGTGCTCTATGACGCCCGGGACGGGC
GGCGCTACCTGGACATGTTCACCTTCTTCGCGTCGTCGGCGCTGGGCATGAACCACCCCGCGCTGGCGCGCGACGCGGAG
TTTCGCGCCGAGCTGGCGGCCGCCGCGCTGAACAAGCCCAGCAATTCCGACGTCTACTCGGTGCCGATGGCCCGCTTCGT
CGAGACCTTCGTCCGGGTGCTGGGCGACCCGGCGCTGCCGCATCTGTTCTTCGTCGACGGCGGCGCGCTGGCCGTGGAGA
ACGCGCTCAAGGTGGCGTTCGACTGGAAGAGCCGGCACAACGAACGGCGCGGTGTCGACCCCGCGCTGGGCACCCGGGTG
CTGCACCTGCGCGGCGCCTTCCACGGCCGCAGCGGCCACACGCTGTCGCTGACCAACACCAAGCCGGTCACGGTGGCCCG
CTTCCCGAGGTTCGACTGGCCGCGGATCGACGCGCCCCACCTGCGGTGCGGGGCCGACATCGACGCCCTGGAGGCCGAGT
CGCTGCGGCAGGCCCGCGCGGCGTTCGCGGCGCACCCGCACGACATCGCCTGCTTCATCGCCGAACCCATCCAGGGCGAG
GGCGGCGACCGCCACTTCCGGCCGGAGTTCTTCGCGGCCATGCGGCGGCTGTGCGACGAACACGACGCTTTGCTGATCTT
CGACGAGGTGCAGACGGGCTGCGGGTTGACCGGAACCGCCTGGGCCTACCACCAATTCGGCGTGCAGCCCGACGTGGTGG
CGTTCGGCAAGAAGACCCAGGTGTGCGGAATCATGGCCGGCCGCCGGGTCGACGAGGTGGCCGACAACGTGTTCGCGGTG
TCGTCGCGGCTGAACTCCACCTGGGGCGGCAACCTGGCCGACATGGTGCGGGCCCGCCGCATCCTGGAGGTGATCGAGGC
CGACGAGCTGTTCGAGCACGCTGCCCGGCAGGGCGCCTACCTGCTGCGCGGCCTGCACGACCTGGCCCGCGAGTTCCCCG
GCCTGGTGCTCGACGTCCGCGGCCGCGGGCTGATGTGCGCGTTCAGCCTGCCCACCACGGCGGACCGCGACGAGCTGATC
GGCCGGCTGTGGCGAGGCGGGGTGATCGTGTTGCCCACGGGCGACGACGGGGTGCGGTTCCGCCCGGCGCTGACCGTCTC
GCGCGGCGAGATCGACGCGGCGATCGGGGCGGTCCGCGACGCGCTGCCGACCTTGGGCTAG

Upstream 100 bases:

>100_bases
CACCATCATATTGAACACATTTTACGACAACAGGGTATATGTACCGTAAATATTACTGCCTATACCTCATGATTTCGTAA
AGATCGGCTACCATAGCCGC

Downstream 100 bases:

>100_bases
CGTCCCGGACCGGTTTACCCGGGTTTGCCGGCGGGTATCTGATCCCGTGCGCATTGCGCTGCCACCGCGCGGCCGCCAGG
GGCGGCGCGTCCGCGGGCCG

Product: L-lysine aminotransferase

Products: NA

Alternate protein names: L-lysine aminotransferase; Lysine 6-aminotransferase [H]

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MTAALERLARARSCTGPDRVHEVLSRSILTDGFDFVLDLDRSRGSVLYDARDGRRYLDMFTFFASSALGMNHPALARDAE
FRAELAAAALNKPSNSDVYSVPMARFVETFVRVLGDPALPHLFFVDGGALAVENALKVAFDWKSRHNERRGVDPALGTRV
LHLRGAFHGRSGHTLSLTNTKPVTVARFPRFDWPRIDAPHLRCGADIDALEAESLRQARAAFAAHPHDIACFIAEPIQGE
GGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWAYHQFGVQPDVVAFGKKTQVCGIMAGRRVDEVADNVFAV
SSRLNSTWGGNLADMVRARRILEVIEADELFEHAARQGAYLLRGLHDLAREFPGLVLDVRGRGLMCAFSLPTTADRDELI
GRLWRGGVIVLPTGDDGVRFRPALTVSRGEIDAAIGAVRDALPTLG

Sequences:

>Translated_446_residues
MTAALERLARARSCTGPDRVHEVLSRSILTDGFDFVLDLDRSRGSVLYDARDGRRYLDMFTFFASSALGMNHPALARDAE
FRAELAAAALNKPSNSDVYSVPMARFVETFVRVLGDPALPHLFFVDGGALAVENALKVAFDWKSRHNERRGVDPALGTRV
LHLRGAFHGRSGHTLSLTNTKPVTVARFPRFDWPRIDAPHLRCGADIDALEAESLRQARAAFAAHPHDIACFIAEPIQGE
GGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWAYHQFGVQPDVVAFGKKTQVCGIMAGRRVDEVADNVFAV
SSRLNSTWGGNLADMVRARRILEVIEADELFEHAARQGAYLLRGLHDLAREFPGLVLDVRGRGLMCAFSLPTTADRDELI
GRLWRGGVIVLPTGDDGVRFRPALTVSRGEIDAAIGAVRDALPTLG
>Mature_445_residues
TAALERLARARSCTGPDRVHEVLSRSILTDGFDFVLDLDRSRGSVLYDARDGRRYLDMFTFFASSALGMNHPALARDAEF
RAELAAAALNKPSNSDVYSVPMARFVETFVRVLGDPALPHLFFVDGGALAVENALKVAFDWKSRHNERRGVDPALGTRVL
HLRGAFHGRSGHTLSLTNTKPVTVARFPRFDWPRIDAPHLRCGADIDALEAESLRQARAAFAAHPHDIACFIAEPIQGEG
GDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWAYHQFGVQPDVVAFGKKTQVCGIMAGRRVDEVADNVFAVS
SRLNSTWGGNLADMVRARRILEVIEADELFEHAARQGAYLLRGLHDLAREFPGLVLDVRGRGLMCAFSLPTTADRDELIG
RLWRGGVIVLPTGDDGVRFRPALTVSRGEIDAAIGAVRDALPTLG

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI188536080, Length=418, Percent_Identity=31.3397129186603, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI38679950, Length=418, Percent_Identity=31.3397129186603, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI38679946, Length=418, Percent_Identity=31.3397129186603, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4557809, Length=449, Percent_Identity=26.5033407572383, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI13994255, Length=466, Percent_Identity=26.8240343347639, Blast_Score=112, Evalue=9e-25,
Organism=Homo sapiens, GI284507298, Length=322, Percent_Identity=30.1242236024845, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI145693181, Length=425, Percent_Identity=29.4117647058824, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=30.4020100502513, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789016, Length=410, Percent_Identity=31.7073170731707, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1789759, Length=400, Percent_Identity=28.5, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1787560, Length=410, Percent_Identity=28.2926829268293, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1786991, Length=326, Percent_Identity=27.6073619631902, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786349, Length=262, Percent_Identity=29.7709923664122, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=457, Percent_Identity=31.5098468271335, Blast_Score=184, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI25144271, Length=402, Percent_Identity=26.3681592039801, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=280, Percent_Identity=28.9285714285714, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32564660, Length=445, Percent_Identity=25.6179775280899, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71992977, Length=374, Percent_Identity=24.331550802139, Blast_Score=75, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321456, Length=469, Percent_Identity=29.8507462686567, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324432, Length=414, Percent_Identity=25.6038647342995, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6323470, Length=417, Percent_Identity=27.5779376498801, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324386, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281366494, Length=471, Percent_Identity=29.9363057324841, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24667139, Length=471, Percent_Identity=29.9363057324841, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24667143, Length=471, Percent_Identity=29.9363057324841, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21357415, Length=414, Percent_Identity=28.5024154589372, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574759, Length=381, Percent_Identity=26.7716535433071, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI161085790, Length=381, Percent_Identity=26.7716535433071, Blast_Score=92, Evalue=6e-19,
Organism=Drosophila melanogaster, GI21356575, Length=441, Percent_Identity=25.6235827664399, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR017657
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.36 [H]

Molecular weight: Translated: 48981; Mature: 48850

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALERLARARSCTGPDRVHEVLSRSILTDGFDFVLDLDRSRGSVLYDARDGRRYLDMF
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCHHHHHHH
TFFASSALGMNHPALARDAEFRAELAAAALNKPSNSDVYSVPMARFVETFVRVLGDPALP
HHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHCCCCCC
HLFFVDGGALAVENALKVAFDWKSRHNERRGVDPALGTRVLHLRGAFHGRSGHTLSLTNT
EEEEECCCHHHHHHHHHEEEEHHHHCCCCCCCCHHHHHEEEEEECCCCCCCCCEEEECCC
KPVTVARFPRFDWPRIDAPHLRCGADIDALEAESLRQARAAFAAHPHDIACFIAEPIQGE
CCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
GGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWAYHQFGVQPDVVAFGKKTQ
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCEECCCCCC
VCGIMAGRRVDEVADNVFAVSSRLNSTWGGNLADMVRARRILEVIEADELFEHAARQGAY
CHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRGLHDLAREFPGLVLDVRGRGLMCAFSLPTTADRDELIGRLWRGGVIVLPTGDDGVRF
HHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCEE
RPALTVSRGEIDAAIGAVRDALPTLG
EEEEEEECCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TAALERLARARSCTGPDRVHEVLSRSILTDGFDFVLDLDRSRGSVLYDARDGRRYLDMF
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECCCCHHHHHHH
TFFASSALGMNHPALARDAEFRAELAAAALNKPSNSDVYSVPMARFVETFVRVLGDPALP
HHHHHHHCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHHCCCCCC
HLFFVDGGALAVENALKVAFDWKSRHNERRGVDPALGTRVLHLRGAFHGRSGHTLSLTNT
EEEEECCCHHHHHHHHHEEEEHHHHCCCCCCCCHHHHHEEEEEECCCCCCCCCEEEECCC
KPVTVARFPRFDWPRIDAPHLRCGADIDALEAESLRQARAAFAAHPHDIACFIAEPIQGE
CCEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
GGDRHFRPEFFAAMRRLCDEHDALLIFDEVQTGCGLTGTAWAYHQFGVQPDVVAFGKKTQ
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHCCCCCCCEECCCCCC
VCGIMAGRRVDEVADNVFAVSSRLNSTWGGNLADMVRARRILEVIEADELFEHAARQGAY
CHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLRGLHDLAREFPGLVLDVRGRGLMCAFSLPTTADRDELIGRLWRGGVIVLPTGDDGVRF
HHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCCCCEE
RPALTVSRGEIDAAIGAVRDALPTLG
EEEEEEECCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]