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The map label for this gene is sseA

Identifier: 41409500

GI number: 41409500

Start: 3777765

End: 3778661

Strand: Direct

Name: sseA

Synonym: MAP3402

Alternate gene names: 41409500

Gene position: 3777765-3778661 (Clockwise)

Preceding gene: 41409499

Following gene: 41409501

Centisome position: 78.22

GC content: 70.01

Gene sequence:

>897_bases
GTGCCACTACCGCCCGATCCACACCCGTCCCTGCAGGAATACGCGCACCCCGAGCGCCTGGTGACCGCCGACTGGCTGTC
GGCCAACCTGGGCGCCCCCGGCCTGGTGATCGTCGAGTCCGACGAGGACGTGCTGCTCTACGACGTCGGCCACATCCCCG
GCGCGGTCAAGATCGACTGGCACACCGACCTCAACGACCCGCGGGTGCGCGACTACATCGACGGCGCGCGGTTCGCCGAG
CTGATGGACCGCAAGGGCATCTCCCGCGACGACACCGTGGTGATCTACGGCGACAAGAGCAACTGGTGGGCGGCCTACGC
GCTGTGGGTGTTCACCCTGTTCGGCCACCCCGACGTGCGGCTGCTCAACGGCGGGCGCGACCTGTGGCTGGCCGAACGCC
GCGAGACCACCCTGGACGTGCCCACCAAGACCTCCACCGGCTACCCCGTCGTCACCCGCAACGACGCGCCCATCCGCGCC
TTCAAGGACGACGTGCTGGCCATCCTGGGCAGCCAGCCGCTGATCGACGTCCGCTCCCCCGACGAGTACACCGGCAAGCG
CACCCACATGCCGGAGTATCCCGAGGAGGGCGTGCTGCGCGGCGGTCACATCCCCACCGCCCGGTCCATCCCCTGGGCCA
AGGCGGTCGACGAGAGCGGGCGTTTCCGCAGCCGCGCGGAACTCGAGGAGCTCTACGGGTTCCTCCGGCCCGACGACAAG
ACCGTGGTGTACTGCCGCATCGGCGAGCGGTCCAGCCACACCTGGTTCGTGCTGACGCATCTGCTGGGCAAGCCGGGGGT
GCGCAACTACGACGGGTCGTGGACCGAATGGGGAAACACCGTGCGCACCCCGATCGTGGCGGGCGAGGAGCCCGGTCAGG
CGCCGGCGGGAGTGTGA

Upstream 100 bases:

>100_bases
GAAAACCCGAAATTCCCGACAACAAGTCGACGTTGGCGCGCCGTGCCACCGACAAAGTCGACGTTGGGCCCCGAGCAACG
AGATGGGTAGGCTCGAAACC

Downstream 100 bases:

>100_bases
CGGCGGCGCGATGAGCATCCCCGCGCCGCTGGCCGAAGTGGTGTCCGACTTCGCCGAAGTGCAGGGCCAGGACAAGCTGG
CGCTGCTGCTGGAATTCGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MPLPPDPHPSLQEYAHPERLVTADWLSANLGAPGLVIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYIDGARFAE
LMDRKGISRDDTVVIYGDKSNWWAAYALWVFTLFGHPDVRLLNGGRDLWLAERRETTLDVPTKTSTGYPVVTRNDAPIRA
FKDDVLAILGSQPLIDVRSPDEYTGKRTHMPEYPEEGVLRGGHIPTARSIPWAKAVDESGRFRSRAELEELYGFLRPDDK
TVVYCRIGERSSHTWFVLTHLLGKPGVRNYDGSWTEWGNTVRTPIVAGEEPGQAPAGV

Sequences:

>Translated_298_residues
MPLPPDPHPSLQEYAHPERLVTADWLSANLGAPGLVIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYIDGARFAE
LMDRKGISRDDTVVIYGDKSNWWAAYALWVFTLFGHPDVRLLNGGRDLWLAERRETTLDVPTKTSTGYPVVTRNDAPIRA
FKDDVLAILGSQPLIDVRSPDEYTGKRTHMPEYPEEGVLRGGHIPTARSIPWAKAVDESGRFRSRAELEELYGFLRPDDK
TVVYCRIGERSSHTWFVLTHLLGKPGVRNYDGSWTEWGNTVRTPIVAGEEPGQAPAGV
>Mature_297_residues
PLPPDPHPSLQEYAHPERLVTADWLSANLGAPGLVIVESDEDVLLYDVGHIPGAVKIDWHTDLNDPRVRDYIDGARFAEL
MDRKGISRDDTVVIYGDKSNWWAAYALWVFTLFGHPDVRLLNGGRDLWLAERRETTLDVPTKTSTGYPVVTRNDAPIRAF
KDDVLAILGSQPLIDVRSPDEYTGKRTHMPEYPEEGVLRGGHIPTARSIPWAKAVDESGRFRSRAELEELYGFLRPDDKT
VVYCRIGERSSHTWFVLTHLLGKPGVRNYDGSWTEWGNTVRTPIVAGEEPGQAPAGV

Specific function: May Be A Sulfotransferase Involved In The Formation Of Thiosulfate. The Rhodanese Activity Of Ssea Is Weak, Its Participation In Detoxification Of Cyanide May Be Small. May Be Involved In The Enhancement Of Serine-Sensitivity. [C]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI17402865, Length=277, Percent_Identity=30.3249097472924, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI194473668, Length=311, Percent_Identity=30.2250803858521, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI61835204, Length=297, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI194473681, Length=297, Percent_Identity=30.3030303030303, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI87082121, Length=282, Percent_Identity=28.3687943262411, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI87081967, Length=297, Percent_Identity=25.9259259259259, Blast_Score=75, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI115534702, Length=248, Percent_Identity=28.6290322580645, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.1 [H]

Molecular weight: Translated: 33419; Mature: 33288

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS00380 RHODANESE_1 ; PS00683 RHODANESE_2 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPPDPHPSLQEYAHPERLVTADWLSANLGAPGLVIVESDEDVLLYDVGHIPGAVKIDW
CCCCCCCCCCHHHHCCCCCEEEHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEE
HTDLNDPRVRDYIDGARFAELMDRKGISRDDTVVIYGDKSNWWAAYALWVFTLFGHPDVR
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEE
LLNGGRDLWLAERRETTLDVPTKTSTGYPVVTRNDAPIRAFKDDVLAILGSQPLIDVRSP
EEECCCCEEEECCCCCEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEECCCC
DEYTGKRTHMPEYPEEGVLRGGHIPTARSIPWAKAVDESGRFRSRAELEELYGFLRPDDK
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
TVVYCRIGERSSHTWFVLTHLLGKPGVRNYDGSWTEWGNTVRTPIVAGEEPGQAPAGV
EEEEEEECCCCCCEEEEEEHHHCCCCCCCCCCCHHHCCCEECCCEEECCCCCCCCCCC
>Mature Secondary Structure 
PLPPDPHPSLQEYAHPERLVTADWLSANLGAPGLVIVESDEDVLLYDVGHIPGAVKIDW
CCCCCCCCCHHHHCCCCCEEEHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCEEEEEE
HTDLNDPRVRDYIDGARFAELMDRKGISRDDTVVIYGDKSNWWAAYALWVFTLFGHPDVR
ECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEE
LLNGGRDLWLAERRETTLDVPTKTSTGYPVVTRNDAPIRAFKDDVLAILGSQPLIDVRSP
EEECCCCEEEECCCCCEECCCCCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCEEECCCC
DEYTGKRTHMPEYPEEGVLRGGHIPTARSIPWAKAVDESGRFRSRAELEELYGFLRPDDK
CCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
TVVYCRIGERSSHTWFVLTHLLGKPGVRNYDGSWTEWGNTVRTPIVAGEEPGQAPAGV
EEEEEEECCCCCCEEEEEEHHHCCCCCCCCCCCHHHCCCEECCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]