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The map label for this gene is udg [H]

Identifier: 41409352

GI number: 41409352

Start: 3612225

End: 3613961

Strand: Direct

Name: udg [H]

Synonym: MAP3254

Alternate gene names: 41409352

Gene position: 3612225-3613961 (Clockwise)

Preceding gene: 41409351

Following gene: 41409353

Centisome position: 74.79

GC content: 73.75

Gene sequence:

>1737_bases
GTGGCCGCCGGACCGGTTCGCGGCGGTGGCCGCGGCGCTGCGCGACGACGGCCACGAGATCCTGATCACCGGATCACCGA
GCGAATTCCACCTCGCGCACACCGTCGCCCGCGCCGCCCGGTTGCCGCGCACCGCCGTGGTGTCCGGAGTCCTCGACCTG
CCGGCGCTGACCGCGCTGGTCGCCGACAGCCGGATGGTGATCTGCGGCGACACCGGTGTGGCGCACCTGGCCGCCGCGAC
CGGCACCGCCTCGGTGGTGCTGTTCGGCCCCACCTCCCCGCGGCGGTGGGGACCGCGCGGGCCGGCGCCGCACGCCGCGC
TGTGGGCCGGCCGCAGCGGCGACCCGCACGCCGCGACGCCGCACCCCGGACTGCTCGAGCTGACCGTCGCGCAGGTGCTG
TCGGCCTGCCGCGGGGTGCTGGGGGAGACGGCATGAGCACCGAGCCGCTGGTCGGCGTGGTCGGTGTCGGCTACGTGGGT
CTGACCACCGCGGTCTGCGTGGCCGCTGCGGGGCGCAAGACCGTTGCGGTGGACATCAACCCGGACCGGGTGGGCAGGCT
GCGCGCCGGGGTGGCGGTGATCGACGAACCCGGGCTGTCCGAGCTGCTGGGTGACGGGCTGGCCGGCGGCGTGCTGCGCT
TCAGCGCCGATTTCGCCGAGCTGGCCGACCGCGACGTCGTCTTCGTGTGCGTGCCCACGCCCAGCGCCCCGGACGGACAC
GCGGACCTGGCCGCGGTGGAGTCGGTGATCGACCGGCTCGGCCGCGTGCTGCGCCGCGGTGCCGTGGTGGCGCTGAAATC
GACCGTCCCGGTCGGCACCACGTCCACCATGGCACAGCGGCTGTGCCACAAGGGGATTCGTGTCGTCTCCACCCCCGAGT
TCCTGCGCGAGGGACGCGCGGTCGACGACTTCCGCAACCCGGACCGGCTGGTGATCGGCAGCCACGACGAACTGGCGGCC
CAGCTGGTGCACCAGGCCTACGGCCTGGCCGGACACCGGGTGCTGCGGATGAGCCCGGAAAGCGCCGAGCTGGCCAAGTA
CGCCAGCAACGCCTTTCTGGCCGTCAAGCTGTCCTACACGAATTCGCTGGCGGCGCTGTGCGCGCGGGTGGGCGCCGACA
TCGACGACGTCACCTGCTGCATGGGCGCCGACCGGCGGATCGGCGCGGAGTTCTTGCGCCCGGGCCCGGGTTGGGGCGGT
TCCTGCCTGCCCAAGGACACCGCGGCGCTGCTGGACATCGCGCACCGGCACCGGGTGTCCTTCGCCGAAGTGGAGGCCGC
CCGGCAGACCAACACCGCGCAGGCACGACGGATCGTCACCGCGCTGCGGCACACCCTCGGCCGGCCGTTGTCGGGTTGCC
GGATCACCGCGCTGGGGCTCACCTTCAAGGCCGCCACCAGTGACACCCGGGAGTCGCCGGCGCTGGCGGCATGCCGCGAA
CTGGCCGCGGCCGGCGCCCAGGTGGCCGGCCACGACCCGCAGTTGCCCAACATCGACCCCGCCGTCCTGCAGCAAAACCG
GGTGACCGCGGTCGACGACCCGTACCGGGCGGCCAAGGCCGCCGACGCGGTCGTGGTGCTGACCGAATGGCCGCAGTTCC
GCAGCCTCGACTGGCGGGCGGTCGCACAGGACGCGCCGCTGGCGGTGGTGCTGGACGCCAGGAATTCGCTGGACCCGGCC
ACCGTGCGGGAAGCCGGCCTGCGCTATCTGGGAAACGGTGTGCCACAAGGGTTTTGA

Upstream 100 bases:

>100_bases
CTTGCGACTCAACCGATATCCTCCTTGAACGCCCGTCCATCCCGCGGGACGAGACCGGTGCCGTGCTGATCCACCCCGGG
GCGTCCGCGCCGGCCCGGCA

Downstream 100 bases:

>100_bases
CTGTTGGTGGCGGGCGCCGGCGACTTTCGGCGCCGCGCCGGCGACTGGCAGGTGGCTGGGAGTCGGCTGACCGGGGCGGG
CGGCAGCGCATAACACCGGC

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MAAGPVRGGGRGAARRRPRDPDHRITERIPPRAHRRPRRPVAAHRRGVRSPRPAGADRAGRRQPDGDLRRHRCGAPGRRD
RHRLGGAVRPHLPAAVGTARAGAARRAVGRPQRRPARRDAAPRTARADRRAGAVGLPRGAGGDGMSTEPLVGVVGVGYVG
LTTAVCVAAAGRKTVAVDINPDRVGRLRAGVAVIDEPGLSELLGDGLAGGVLRFSADFAELADRDVVFVCVPTPSAPDGH
ADLAAVESVIDRLGRVLRRGAVVALKSTVPVGTTSTMAQRLCHKGIRVVSTPEFLREGRAVDDFRNPDRLVIGSHDELAA
QLVHQAYGLAGHRVLRMSPESAELAKYASNAFLAVKLSYTNSLAALCARVGADIDDVTCCMGADRRIGAEFLRPGPGWGG
SCLPKDTAALLDIAHRHRVSFAEVEAARQTNTAQARRIVTALRHTLGRPLSGCRITALGLTFKAATSDTRESPALAACRE
LAAAGAQVAGHDPQLPNIDPAVLQQNRVTAVDDPYRAAKAADAVVVLTEWPQFRSLDWRAVAQDAPLAVVLDARNSLDPA
TVREAGLRYLGNGVPQGF

Sequences:

>Translated_578_residues
MAAGPVRGGGRGAARRRPRDPDHRITERIPPRAHRRPRRPVAAHRRGVRSPRPAGADRAGRRQPDGDLRRHRCGAPGRRD
RHRLGGAVRPHLPAAVGTARAGAARRAVGRPQRRPARRDAAPRTARADRRAGAVGLPRGAGGDGMSTEPLVGVVGVGYVG
LTTAVCVAAAGRKTVAVDINPDRVGRLRAGVAVIDEPGLSELLGDGLAGGVLRFSADFAELADRDVVFVCVPTPSAPDGH
ADLAAVESVIDRLGRVLRRGAVVALKSTVPVGTTSTMAQRLCHKGIRVVSTPEFLREGRAVDDFRNPDRLVIGSHDELAA
QLVHQAYGLAGHRVLRMSPESAELAKYASNAFLAVKLSYTNSLAALCARVGADIDDVTCCMGADRRIGAEFLRPGPGWGG
SCLPKDTAALLDIAHRHRVSFAEVEAARQTNTAQARRIVTALRHTLGRPLSGCRITALGLTFKAATSDTRESPALAACRE
LAAAGAQVAGHDPQLPNIDPAVLQQNRVTAVDDPYRAAKAADAVVVLTEWPQFRSLDWRAVAQDAPLAVVLDARNSLDPA
TVREAGLRYLGNGVPQGF
>Mature_577_residues
AAGPVRGGGRGAARRRPRDPDHRITERIPPRAHRRPRRPVAAHRRGVRSPRPAGADRAGRRQPDGDLRRHRCGAPGRRDR
HRLGGAVRPHLPAAVGTARAGAARRAVGRPQRRPARRDAAPRTARADRRAGAVGLPRGAGGDGMSTEPLVGVVGVGYVGL
TTAVCVAAAGRKTVAVDINPDRVGRLRAGVAVIDEPGLSELLGDGLAGGVLRFSADFAELADRDVVFVCVPTPSAPDGHA
DLAAVESVIDRLGRVLRRGAVVALKSTVPVGTTSTMAQRLCHKGIRVVSTPEFLREGRAVDDFRNPDRLVIGSHDELAAQ
LVHQAYGLAGHRVLRMSPESAELAKYASNAFLAVKLSYTNSLAALCARVGADIDDVTCCMGADRRIGAEFLRPGPGWGGS
CLPKDTAALLDIAHRHRVSFAEVEAARQTNTAQARRIVTALRHTLGRPLSGCRITALGLTFKAATSDTRESPALAACREL
AAAGAQVAGHDPQLPNIDPAVLQQNRVTAVDDPYRAAKAADAVVVLTEWPQFRSLDWRAVAQDAPLAVVLDARNSLDPAT
VREAGLRYLGNGVPQGF

Specific function: Catalyzes The Oxidation Of Udp-Mannac To Udp-N- Acetylmannosaminuronic Acid (Udp-Mannaca). [C]

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=443, Percent_Identity=32.7313769751693, Blast_Score=209, Evalue=7e-54,
Organism=Homo sapiens, GI296040438, Length=345, Percent_Identity=33.9130434782609, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI296040443, Length=295, Percent_Identity=35.5932203389831, Blast_Score=170, Evalue=4e-42,
Organism=Escherichia coli, GI48994968, Length=431, Percent_Identity=28.0742459396752, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1788340, Length=352, Percent_Identity=29.5454545454545, Blast_Score=129, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=459, Percent_Identity=32.4618736383442, Blast_Score=203, Evalue=3e-52,
Organism=Drosophila melanogaster, GI17136908, Length=454, Percent_Identity=33.2599118942731, Blast_Score=206, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 61190; Mature: 61059

Theoretical pI: Translated: 11.52; Mature: 11.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGPVRGGGRGAARRRPRDPDHRITERIPPRAHRRPRRPVAAHRRGVRSPRPAGADRAG
CCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCCHHHHHCCCCCCCCCCCCCCC
RRQPDGDLRRHRCGAPGRRDRHRLGGAVRPHLPAAVGTARAGAARRAVGRPQRRPARRDA
CCCCCHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCC
APRTARADRRAGAVGLPRGAGGDGMSTEPLVGVVGVGYVGLTTAVCVAAAGRKTVAVDIN
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCEEEEEECC
PDRVGRLRAGVAVIDEPGLSELLGDGLAGGVLRFSADFAELADRDVVFVCVPTPSAPDGH
HHHHHHHHCCEEEECCCCHHHHHCCCHHCCHHHHCCCHHHHCCCCEEEEEECCCCCCCCC
ADLAAVESVIDRLGRVLRRGAVVALKSTVPVGTTSTMAQRLCHKGIRVVSTPEFLREGRA
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECHHHHHCCCC
VDDFRNPDRLVIGSHDELAAQLVHQAYGLAGHRVLRMSPESAELAKYASNAFLAVKLSYT
CHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEEEECH
NSLAALCARVGADIDDVTCCMGADRRIGAEFLRPGPGWGGSCLPKDTAALLDIAHRHRVS
HHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
FAEVEAARQTNTAQARRIVTALRHTLGRPLSGCRITALGLTFKAATSDTRESPALAACRE
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
LAAAGAQVAGHDPQLPNIDPAVLQQNRVTAVDDPYRAAKAADAVVVLTEWPQFRSLDWRA
HHHCCCHHCCCCCCCCCCCHHHHCCCCCEECCCCHHHHHHCCEEEEEECCCCCCCCCHHH
VAQDAPLAVVLDARNSLDPATVREAGLRYLGNGVPQGF
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AAGPVRGGGRGAARRRPRDPDHRITERIPPRAHRRPRRPVAAHRRGVRSPRPAGADRAG
CCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHCCCCCCHHHHHCCCCCCCCCCCCCCC
RRQPDGDLRRHRCGAPGRRDRHRLGGAVRPHLPAAVGTARAGAARRAVGRPQRRPARRDA
CCCCCHHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCC
APRTARADRRAGAVGLPRGAGGDGMSTEPLVGVVGVGYVGLTTAVCVAAAGRKTVAVDIN
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCEEEEEECC
PDRVGRLRAGVAVIDEPGLSELLGDGLAGGVLRFSADFAELADRDVVFVCVPTPSAPDGH
HHHHHHHHCCEEEECCCCHHHHHCCCHHCCHHHHCCCHHHHCCCCEEEEEECCCCCCCCC
ADLAAVESVIDRLGRVLRRGAVVALKSTVPVGTTSTMAQRLCHKGIRVVSTPEFLREGRA
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEECHHHHHCCCC
VDDFRNPDRLVIGSHDELAAQLVHQAYGLAGHRVLRMSPESAELAKYASNAFLAVKLSYT
CHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHCCCEEEEEEECH
NSLAALCARVGADIDDVTCCMGADRRIGAEFLRPGPGWGGSCLPKDTAALLDIAHRHRVS
HHHHHHHHHHCCCCCHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCH
FAEVEAARQTNTAQARRIVTALRHTLGRPLSGCRITALGLTFKAATSDTRESPALAACRE
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCHHHHHHHH
LAAAGAQVAGHDPQLPNIDPAVLQQNRVTAVDDPYRAAKAADAVVVLTEWPQFRSLDWRA
HHHCCCHHCCCCCCCCCCCHHHHCCCCCEECCCCHHHHHHCCEEEEEECCCCCCCCCHHH
VAQDAPLAVVLDARNSLDPATVREAGLRYLGNGVPQGF
HCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]