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The map label for this gene is fadE1_2

Identifier: 41409220

GI number: 41409220

Start: 3472890

End: 3474185

Strand: Direct

Name: fadE1_2

Synonym: MAP3122

Alternate gene names: 41409220

Gene position: 3472890-3474185 (Clockwise)

Preceding gene: 41409219

Following gene: 41409225

Centisome position: 71.91

GC content: 66.59

Gene sequence:

>1296_bases
ATGTCGTGGGACTTTTCCACCGAACCCCAGTGGGCGCGGCAACTCGAATGGGTCGAGGATTTCGTGCGCGAGGAGTGCGA
GCCGATCGACCTGATCGTCAAGGAATCTCACGACCTCGATGACCCGGTGCGCCAAGCGCTGATCCCGCCGCTGCAGAAGA
TCGTCAAGGAGCGCGGATTGTGGGCCACCCACCTGGGTCCGCACCTGGGCGGCCCGGGCTACGGGCAGGTGAAACTCGCG
CTGCTCAACGAGATCCTGGGCCGCTCGGAATGCGCGCCGATCGTCTTCGGCTCCCAGGCACCCGATTCCGGCAACAGCGA
GATCCTGGCGCACTACGGCACACCGGAACTCAAGGCCCGCTACCTCGAGCCGCTGCTGGACAACCGCATCGTGTCGTGCT
TCTCGATGACCGAACCGCAGGGCGGGGCCGACCCGAAGGTGTTTCGCACCACCGCGGTGCCCGACGGCGACCACTGGGTG
ATCAACGGCGAGAAGTGGTTCTCGTCGTTCGCCTCGATGGCCTCGTTCATCATCGTGATGGCGATGACCGATCCGGAAGC
GCCGCCGTATCAACGCTATTCGATGTTCGTCGTTCCCGGCGACACTCCCGGCATCACCGTGCTGCGCGACGTCGGGCTGG
GCTATCAGCCCCTCGGCGGCGGACGGGAAGGATACGTCCGCTACGAAAACGTCCGGGTGCCGGCCGATCACATGCTGGGC
CCGCGCGGCGGCGCGTTCGTCGTCGCGCAAACCCGGCTGGGCGGCGGGCGGATTCACCACGCCATGCGCACCGTCGGCCT
GGTGCGCCGGATCTTCGACATGATCTGCGAGCGGGCGGTGTCGCGCTACACCCAGGGCGAGGTGCTGGCGAACAAGCAGC
TGGTGCAGGAGATGGTCGCCGACTCCTGGATGGAGATCGAGGCGTTTCGGCTGCTGACACTGCAAACCGCTTGGAAGATC
GACCAATTCAACGATTACCGGGCGGTGCGGGCCGACATCTCGGCGGTGAAGGCGATGATGCAGAGGGTGCTGCACGACGT
GTCGGCGCGGGCGCTGCAGCTGCACGGCTCGCTGGGCACCACGCACGAGATGCCGTTCGTGCAGTACCTGGTGGAGTCCT
TCGTGCTCGGCCTGGCCGACGGCCCGACCGAGGTGCACAAGGTGACGCTGGCCCGGCTGCTGCTCAAAGACCGTGCGCCC
GCGCCGGATCTGTTTCCCTCCGAGCATTTGCTGCGGCTGCGCGCGGCGGCGGAGGCGAAATTCGCCGACAAGCTGGCGGG
AATTCCCCGTGGCTAG

Upstream 100 bases:

>100_bases
GCTGGAGAACCGCAACCAGGTGATCGCGCACGCAACCGACGAGGCGGCGGCGCGCCGGCAGATGTGGTCGCGGTGAACCG
TAACCCGGAGAGGACGGCAG

Downstream 100 bases:

>100_bases
ACGGCTTTGGTGACGCCGACGTAGGACAGCACCACATCGGATTCGTCGGTCACCCGGTTGAGCACCGCATAGGACCGGAT
GAAGGACTGGCCCACGCAGC

Product: FadE1_2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSWDFSTEPQWARQLEWVEDFVREECEPIDLIVKESHDLDDPVRQALIPPLQKIVKERGLWATHLGPHLGGPGYGQVKLA
LLNEILGRSECAPIVFGSQAPDSGNSEILAHYGTPELKARYLEPLLDNRIVSCFSMTEPQGGADPKVFRTTAVPDGDHWV
INGEKWFSSFASMASFIIVMAMTDPEAPPYQRYSMFVVPGDTPGITVLRDVGLGYQPLGGGREGYVRYENVRVPADHMLG
PRGGAFVVAQTRLGGGRIHHAMRTVGLVRRIFDMICERAVSRYTQGEVLANKQLVQEMVADSWMEIEAFRLLTLQTAWKI
DQFNDYRAVRADISAVKAMMQRVLHDVSARALQLHGSLGTTHEMPFVQYLVESFVLGLADGPTEVHKVTLARLLLKDRAP
APDLFPSEHLLRLRAAAEAKFADKLAGIPRG

Sequences:

>Translated_431_residues
MSWDFSTEPQWARQLEWVEDFVREECEPIDLIVKESHDLDDPVRQALIPPLQKIVKERGLWATHLGPHLGGPGYGQVKLA
LLNEILGRSECAPIVFGSQAPDSGNSEILAHYGTPELKARYLEPLLDNRIVSCFSMTEPQGGADPKVFRTTAVPDGDHWV
INGEKWFSSFASMASFIIVMAMTDPEAPPYQRYSMFVVPGDTPGITVLRDVGLGYQPLGGGREGYVRYENVRVPADHMLG
PRGGAFVVAQTRLGGGRIHHAMRTVGLVRRIFDMICERAVSRYTQGEVLANKQLVQEMVADSWMEIEAFRLLTLQTAWKI
DQFNDYRAVRADISAVKAMMQRVLHDVSARALQLHGSLGTTHEMPFVQYLVESFVLGLADGPTEVHKVTLARLLLKDRAP
APDLFPSEHLLRLRAAAEAKFADKLAGIPRG
>Mature_430_residues
SWDFSTEPQWARQLEWVEDFVREECEPIDLIVKESHDLDDPVRQALIPPLQKIVKERGLWATHLGPHLGGPGYGQVKLAL
LNEILGRSECAPIVFGSQAPDSGNSEILAHYGTPELKARYLEPLLDNRIVSCFSMTEPQGGADPKVFRTTAVPDGDHWVI
NGEKWFSSFASMASFIIVMAMTDPEAPPYQRYSMFVVPGDTPGITVLRDVGLGYQPLGGGREGYVRYENVRVPADHMLGP
RGGAFVVAQTRLGGGRIHHAMRTVGLVRRIFDMICERAVSRYTQGEVLANKQLVQEMVADSWMEIEAFRLLTLQTAWKID
QFNDYRAVRADISAVKAMMQRVLHDVSARALQLHGSLGTTHEMPFVQYLVESFVLGLADGPTEVHKVTLARLLLKDRAPA
PDLFPSEHLLRLRAAAEAKFADKLAGIPRG

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=380, Percent_Identity=36.0526315789474, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI211971008, Length=362, Percent_Identity=38.6740331491713, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI48976061, Length=362, Percent_Identity=38.6740331491713, Blast_Score=217, Evalue=1e-56,
Organism=Homo sapiens, GI4557233, Length=387, Percent_Identity=28.9405684754522, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI187960098, Length=402, Percent_Identity=28.3582089552239, Blast_Score=135, Evalue=9e-32,
Organism=Homo sapiens, GI4557231, Length=402, Percent_Identity=28.3582089552239, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI4501859, Length=376, Percent_Identity=27.6595744680851, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI21361497, Length=380, Percent_Identity=27.1052631578947, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI7656849, Length=346, Percent_Identity=26.0115606936416, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI4557235, Length=384, Percent_Identity=26.3020833333333, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=26.2337662337662, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI4501857, Length=355, Percent_Identity=26.1971830985915, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI226958412, Length=330, Percent_Identity=23.6363636363636, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI226958414, Length=330, Percent_Identity=23.6363636363636, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4503943, Length=411, Percent_Identity=22.3844282238443, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI87081958, Length=264, Percent_Identity=25, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1786223, Length=327, Percent_Identity=24.1590214067278, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562446, Length=361, Percent_Identity=36.01108033241, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17534899, Length=352, Percent_Identity=29.5454545454545, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI17569725, Length=339, Percent_Identity=29.4985250737463, Blast_Score=143, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17570075, Length=331, Percent_Identity=26.5861027190332, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=375, Percent_Identity=27.4666666666667, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17508101, Length=340, Percent_Identity=27.9411764705882, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=388, Percent_Identity=26.2886597938144, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71982178, Length=262, Percent_Identity=29.3893129770992, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=372, Percent_Identity=24.4623655913978, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71990804, Length=266, Percent_Identity=29.3233082706767, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=351, Percent_Identity=22.7920227920228, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17551932, Length=339, Percent_Identity=24.188790560472, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=355, Percent_Identity=24.2253521126761, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=273, Percent_Identity=25.6410256410256, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=193, Percent_Identity=29.5336787564767, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17534353, Length=287, Percent_Identity=23.6933797909408, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24660351, Length=394, Percent_Identity=28.9340101522843, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24666513, Length=385, Percent_Identity=28.3116883116883, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI21356377, Length=362, Percent_Identity=28.4530386740331, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI24646207, Length=357, Percent_Identity=26.0504201680672, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363737, Length=301, Percent_Identity=26.2458471760797, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355753, Length=377, Percent_Identity=24.6684350132626, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19920834, Length=286, Percent_Identity=23.7762237762238, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.21 [H]

Molecular weight: Translated: 47963; Mature: 47831

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWDFSTEPQWARQLEWVEDFVREECEPIDLIVKESHDLDDPVRQALIPPLQKIVKERGL
CCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
WATHLGPHLGGPGYGQVKLALLNEILGRSECAPIVFGSQAPDSGNSEILAHYGTPELKAR
EEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCHHHHHH
YLEPLLDNRIVSCFSMTEPQGGADPKVFRTTAVPDGDHWVINGEKWFSSFASMASFIIVM
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHEEEE
AMTDPEAPPYQRYSMFVVPGDTPGITVLRDVGLGYQPLGGGREGYVRYENVRVPADHMLG
EECCCCCCCCCCEEEEEEECCCCCEEHHHHCCCCCCCCCCCCCCCEEEECEECCHHHHCC
PRGGAFVVAQTRLGGGRIHHAMRTVGLVRRIFDMICERAVSRYTQGEVLANKQLVQEMVA
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DSWMEIEAFRLLTLQTAWKIDQFNDYRAVRADISAVKAMMQRVLHDVSARALQLHGSLGT
HCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
THEMPFVQYLVESFVLGLADGPTEVHKVTLARLLLKDRAPAPDLFPSEHLLRLRAAAEAK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
FADKLAGIPRG
HHHHHCCCCCC
>Mature Secondary Structure 
SWDFSTEPQWARQLEWVEDFVREECEPIDLIVKESHDLDDPVRQALIPPLQKIVKERGL
CCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
WATHLGPHLGGPGYGQVKLALLNEILGRSECAPIVFGSQAPDSGNSEILAHYGTPELKAR
EEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEEECCCHHHHHH
YLEPLLDNRIVSCFSMTEPQGGADPKVFRTTAVPDGDHWVINGEKWFSSFASMASFIIVM
HHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHEEEE
AMTDPEAPPYQRYSMFVVPGDTPGITVLRDVGLGYQPLGGGREGYVRYENVRVPADHMLG
EECCCCCCCCCCEEEEEEECCCCCEEHHHHCCCCCCCCCCCCCCCEEEECEECCHHHHCC
PRGGAFVVAQTRLGGGRIHHAMRTVGLVRRIFDMICERAVSRYTQGEVLANKQLVQEMVA
CCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DSWMEIEAFRLLTLQTAWKIDQFNDYRAVRADISAVKAMMQRVLHDVSARALQLHGSLGT
HCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
THEMPFVQYLVESFVLGLADGPTEVHKVTLARLLLKDRAPAPDLFPSEHLLRLRAAAEAK
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
FADKLAGIPRG
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629170; 12420174 [H]