| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is idsA2_2
Identifier: 41409167
GI number: 41409167
Start: 3414585
End: 3415733
Strand: Direct
Name: idsA2_2
Synonym: MAP3069
Alternate gene names: 41409167
Gene position: 3414585-3415733 (Clockwise)
Preceding gene: 41409166
Following gene: 41409168
Centisome position: 70.7
GC content: 70.67
Gene sequence:
>1149_bases GTGCCGTCCGGGAGGGAGCGCTGGGACACCATGGGAGCTTTGTCGTTTTCGCCCACCACCACGGCGGCGGCGCCGGCCTG GACGCGCATCGACGACTTCGGCGGGTGGCGGGCACACGTTCGGGCGATGGTGTTGGACGAGGTCGCCGACTTCGTCGGAA TGCGACGCGCCGACGAACTCGACCGGGCGGGGATCGGGACCGCGGGCGACATCCTGGTTCAGTTCGTCTCCGGCGGCAAG TGCCTGCGGTCGACGTTCGTCTACCTGGGCTGGCTGTGTGGGGCACCGCGCGACCGGGCGGCGCTGCGGGCCGCCGCCAG TTTCGAGCTGCTGCACGCCTTCGCACTGCTGCAAGACGATGTGATGGACGGTGCGCAGGAACGGCGGGGCCGTCCGGCCG CGCATCTGCAGTTCGGCCGCTGGCATCAAGACCGCGGATTGTCCGGCTCGCCACGGCGATTCGGTGAATCGGCCGCCATC CTGTTGGGCGATCTCTGCCTGATCTGGGCCGAACAGATGCTGCGCGACAGCGGACTCGAAGCGCGCCGCCTGCAACGCGC GTGGCCGCGCTATGACGCCATGCGCGTCGAGCTCGCGGTGGGCCAGTTCGCCGACCTGACCAACGACATCCGGCAGTCAC CGGGGCTGGACGCCGTGCTGGAGGTGGCGCGCCGCAAATCGGGTAACTACACGGTGCGCCGGCCGCTGGAAATCGGCGCG ACGATGGCCGGGTGCGACGACCGGACGGTGGCCCGGCTGAGCCGCTACGGCGCGGCGGTGGGTGAAGCCTTCCAGCTGCG CGACGACGTGCTGGGCGTCTTCGGCTCGCCGGCGGTCACCGGGAAGCCCTGCGCCGCAGATCTGTTCGAGCGCAAGGCCA CCGCCGTGGTGGTGAGCGCCCACCAACTCGCCGATCCGCCGGTCCGGCGTGAGCTCATCGAGCTCGCCACTCGTGACGTG CTGGACGCGGCCGCGATCGAGAGGTGGAAAGCGCTGATCGTCGAGACCGGAGCGGTGCGGCTGATCGAGCGGATGATCAG CGACCGCGTCGCGTCGGCACGCGAGCAGCTGTGCGGCCTGCCCGTCGACGAATCGGTGCGCGCCGCGCTGGCCGAGATGG CGGCCGTCTGTACGGATCGCGCCGAATGA
Upstream 100 bases:
>100_bases GCGGACCGCGCCGAGCGGGCCTGACGTCAGGGCTGTGGTTTTGTCCGCGTCATCGAGGGTATGACCGGCGGTGTTCGGCC CGGGCGGGACTGGGCAGGCC
Downstream 100 bases:
>100_bases CCGCCACCGGCACGGGAGTTCGGTGAGCATGCGGGCCATCGAGGGCTCCGCCGATCACGTCGTGGTGATCGGGGCCGGTC TGGCCGGCCTGTCCGCGGCG
Product: IdsA2_2
Products: NA
Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]
Number of amino acids: Translated: 382; Mature: 381
Protein sequence:
>382_residues MPSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADELDRAGIGTAGDILVQFVSGGK CLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDDVMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAI LLGDLCLIWAEQMLRDSGLEARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSAHQLADPPVRRELIELATRDV LDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGLPVDESVRAALAEMAAVCTDRAE
Sequences:
>Translated_382_residues MPSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADELDRAGIGTAGDILVQFVSGGK CLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDDVMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAI LLGDLCLIWAEQMLRDSGLEARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSAHQLADPPVRRELIELATRDV LDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGLPVDESVRAALAEMAAVCTDRAE >Mature_381_residues PSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADELDRAGIGTAGDILVQFVSGGKC LRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDDVMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAIL LGDLCLIWAEQMLRDSGLEARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGAT MAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSAHQLADPPVRRELIELATRDVL DAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGLPVDESVRAALAEMAAVCTDRAE
Specific function: Unknown
COG id: COG0142
COG function: function code H; Geranylgeranyl pyrophosphate synthase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the FPP/GGPP synthase family [H]
Homologues:
Organism=Escherichia coli, GI1786623, Length=280, Percent_Identity=31.0714285714286, Blast_Score=65, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17508563, Length=214, Percent_Identity=27.5700934579439, Blast_Score=69, Evalue=3e-12,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000092 - InterPro: IPR017446 - InterPro: IPR008949 [H]
Pfam domain/function: PF00348 polyprenyl_synt [H]
EC number: =2.5.1.1; =2.5.1.10 [H]
Molecular weight: Translated: 41732; Mature: 41601
Theoretical pI: Translated: 6.67; Mature: 6.67
Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.8 %Cys (Translated Protein) 2.6 %Met (Translated Protein) 4.5 %Cys+Met (Translated Protein) 1.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADEL CCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH DRAGIGTAGDILVQFVSGGKCLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDD HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH VMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAILLGDLCLIWAEQMLRDSGLE HHCCHHHHCCCCCHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCH ARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA HHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECHHHHCC TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSA CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEH HQLADPPVRRELIELATRDVLDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGL HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC PVDESVRAALAEMAAVCTDRAE CCCHHHHHHHHHHHHHHHCCCC >Mature Secondary Structure PSGRERWDTMGALSFSPTTTAAAPAWTRIDDFGGWRAHVRAMVLDEVADFVGMRRADEL CCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH DRAGIGTAGDILVQFVSGGKCLRSTFVYLGWLCGAPRDRAALRAAASFELLHAFALLQDD HHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH VMDGAQERRGRPAAHLQFGRWHQDRGLSGSPRRFGESAAILLGDLCLIWAEQMLRDSGLE HHCCHHHHCCCCCHHCCCCCCCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCH ARRLQRAWPRYDAMRVELAVGQFADLTNDIRQSPGLDAVLEVARRKSGNYTVRRPLEIGA HHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEECHHHHCC TMAGCDDRTVARLSRYGAAVGEAFQLRDDVLGVFGSPAVTGKPCAADLFERKATAVVVSA CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEEEH HQLADPPVRRELIELATRDVLDAAAIERWKALIVETGAVRLIERMISDRVASAREQLCGL HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC PVDESVRAALAEMAAVCTDRAE CCCHHHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8688087 [H]