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The map label for this gene is hupB

Identifier: 41409122

GI number: 41409122

Start: 3364374

End: 3365012

Strand: Reverse

Name: hupB

Synonym: MAP3024c

Alternate gene names: 41409122

Gene position: 3365012-3364374 (Counterclockwise)

Preceding gene: 41409123

Following gene: 41409118

Centisome position: 69.67

GC content: 68.08

Gene sequence:

>639_bases
ATGAACAAGGCAGAGCTCATTGATGTGCTCACACAGAAATTGAACACGGACCGTCGGCAGGCGACCGCAGCGGTCGAGAA
TGTCGTCGACACCATTGTGCGTGCGGTACACAAGGGCGACAGCGTCACGATCACCGGGTTCGGTGTATTCGAACAGCGGC
GGCGCGCCGCACGGGTGGCCCGCAACCCGCGTACCGGTGAGACGGTGAAGGTGAAGCCGACGTCCGTCCCGGCGTTCCGC
CCCGGCGCTCAATTCAAAGCGGTTGTCTCTGGCGCACAGCGTCTCCCGTCCGAGGGCCCGGCCGTCAAGCGCGGCGTGGT
CGGCGGCGCGGCCAAGAAGACCGCCGCCAAGAAGGCGCCCGCCAAGAAGGCTGCGGCGAAGAAGGCTCCGGCCAAGAAGG
CCGCCGCCAAGAAGGCCCCGGCGAAGAAGGCTGCGGTCAAGAAGGCTCCGGCCCGCAAGGCCGCGACCAAGGCTCCGGTG
CGCAAGGCCGCGACCAAGGCTCCGGCCAAGAAGGTTGCGGCGAAGAAGGCTCCGGCCAAGAAGGCCGCGACCAAGGCTCC
GGCCAAGAAGGCCGCCAGCAAGGCTCCGGCTCGCAAGGCCGCGGCCAAGAAGACGACCGCGCGTCGCGGCCGCAAGTAG

Upstream 100 bases:

>100_bases
CGCCGTGAAATTGCGCGTGGCTCTTGGAAATTTGCTGGGTGAGGGTTTACCGTGTCCACTAGTCGGTTCAAATCGAGGAC
CACTAGTGTCGGAGGGATTG

Downstream 100 bases:

>100_bases
GCAGAGCACGTCCTAGACACGAATACCCTTCGGCCGGCAGCGGTGCCGCCCGGAGGGTATTCGTGTGCTAGCGAGCGGGC
ACGCCGCCGCGAACTCAGGC

Product: HupB

Products: NA

Alternate protein names: Histone-like protein; Hlp [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MNKAELIDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFR
PGAQFKAVVSGAQRLPSEGPAVKRGVVGGAAKKTAAKKAPAKKAAAKKAPAKKAAAKKAPAKKAAVKKAPARKAATKAPV
RKAATKAPAKKVAAKKAPAKKAATKAPAKKAASKAPARKAAAKKTTARRGRK

Sequences:

>Translated_212_residues
MNKAELIDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFR
PGAQFKAVVSGAQRLPSEGPAVKRGVVGGAAKKTAAKKAPAKKAAAKKAPAKKAAAKKAPAKKAAVKKAPARKAATKAPV
RKAATKAPAKKVAAKKAPAKKAATKAPAKKAASKAPARKAAAKKTTARRGRK
>Mature_212_residues
MNKAELIDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVARNPRTGETVKVKPTSVPAFR
PGAQFKAVVSGAQRLPSEGPAVKRGVVGGAAKKTAAKKAPAKKAAAKKAPAKKAAAKKAPAKKAAVKKAPARKAATKAPV
RKAATKAPAKKVAAKKAPAKKAATKAPAKKAASKAPARKAAAKKTTARRGRK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Secreted, cell wall [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1790433, Length=82, Percent_Identity=42.6829268292683, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=38.0434782608696, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=34.4444444444444, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: 1380 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 21936; Mature: 21936

Theoretical pI: Translated: 12.48; Mature: 12.48

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
0.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKAELIDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
RNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPSEGPAVKRGVVGGAAKKTAAKKAP
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCC
AKKAAAKKAPAKKAAAKKAPAKKAAVKKAPARKAATKAPVRKAATKAPAKKVAAKKAPAK
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KAATKAPAKKAASKAPARKAAAKKTTARRGRK
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKAELIDVLTQKLNTDRRQATAAVENVVDTIVRAVHKGDSVTITGFGVFEQRRRAARVA
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHH
RNPRTGETVKVKPTSVPAFRPGAQFKAVVSGAQRLPSEGPAVKRGVVGGAAKKTAAKKAP
CCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHCC
AKKAAAKKAPAKKAAAKKAPAKKAAVKKAPARKAATKAPVRKAATKAPAKKVAAKKAPAK
HHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KAATKAPAKKAASKAPARKAAAKKTTARRGRK
HHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]