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The map label for this gene is ffh

Identifier: 41409081

GI number: 41409081

Start: 3315692

End: 3317245

Strand: Reverse

Name: ffh

Synonym: MAP2983c

Alternate gene names: 41409081

Gene position: 3317245-3315692 (Counterclockwise)

Preceding gene: 41409084

Following gene: 41409080

Centisome position: 68.68

GC content: 70.59

Gene sequence:

>1554_bases
GTGTTTGAATCGCTGTCCGACCGATTGACCGGTGCCCTTGCGGGACTGCGCGGCAAGGGTCGACTGACCGACGCCGACAT
CGAGGCCACCACCCGCGAAATCCGGCTGGCGCTGCTGGAAGCCGACGTGTCGCTGCCCGTCGTGCGCGCGTTCGTCACCC
GGATCAAGGAGCGCGCCAAGGGCGCCGAGGTGTCCGGCGCGCTGAACCCGGCGCAGCAGGTCGTCAAGATCGTCAACGAA
GAGCTCATCGGCATCCTGGGCGGCGAGACCCGCCAGCTCGCGTTCGCCAAGACTCCACCGACCGTGATCATGCTCGCCGG
TCTGCAGGGTTCCGGTAAGACGTCGCTGGCCGGCAAGCTGGCCGCCTGGCTGCGCGGGCAGGGCCACACCCCGCTGCTGG
TGGCCTGCGACCTGCAGCGCCCCGCCGCGGTGAACCAGCTGCAGGTCGTCGGCGAGCGCGCCGGCGTCCCGGTGTTTGCG
CCGCATCCCGGCGCCTCACCCGAGTCCGGGCCCGGCGACCCGGTGGCGGTGGCCGCACAGGGCCTCGCCGAGGCCCGGGC
CAAGCACCATGACGTCGTCATCGTCGACACCGCCGGCCGGCTGGGCATCGACGACGAGCTGATGGCCCAGGCCGCGGCCA
TCCGCGACGCCATCGACCCCGACGAGATCCTGTTCGTGCTGGACGCGATGATCGGCCAGGACGCCGTCACCACCGCCGAG
GCCTTCCGCGAGGGCGTCGGCTTCACCGGCGTGGTGCTGACCAAACTCGACGGCGACGCCCGTGGCGGCGCGGCGCTGTC
GGTGCGCGAGGTCACCGGGGTGCCGATCCTGTTCGCCTCCACCGGCGAGAAGCTGGAGGACTTCGACGTCTTCCACCCCG
ACCGGATGTCCAGCCGCATCCTGGGCATGGGCGACGTGCTGAGCCTGATCGAGCAGGCCGAGCAGGTCTTCGACGCCGAA
CAGGCCGAGGCCGCCGCCGTCAAGATCGGCAGCGGCGAGCTCACCCTCGAGGACTTCCTGGAACAGATGCTGGCCATCCG
CAAGATGGGGCCGATCGGCAACCTGCTGGGCATGCTGCCCGGCGCCGGGCAGATGAAGGACGCGCTGGCCGCCGTCGACG
ACAAGCAGCTCGACCGGCTGCAGGCCATCATCCGCGGGATGACCCCCGAAGAGCGGGCCGACCCGAAGATCATCAACGCG
TCGCGGCGGCTGCGCATCGCCAACGGCTCCGGCGTGACGGTGTCGGAGGTCAACCAGCTCGTGGACCGCTTCTTCGAGGC
CCGCAAGATGATGTCGTCGATGCTCGGCGGCATGGGGATTCCCGGGCTGGGCCGCAAGTCGGCGACGCGAAAAGCCAAGG
GCGCCAAAGGTAAAGCCAAGAAGGGCAAGAAGGGCGCGCGCGGCCCCACCCCGCCGGAGGTGCGCAGCCCGCTGGGGCCC
GGGATGCCGGCCGGGTTCCCCGACCTGTCGCAGCTGCCCGAGGGCCTCAACGAGCTGCCACCCGGGCTGGCCGACTTCGA
CCTGTCCAAGCTGAAGTTCCCGGGCAACAAGTAG

Upstream 100 bases:

>100_bases
TGGCGCTCGACGCCGAGGGTCACGCCAGCGTGACGCTCGCGCCGAACGGCACCTGCTGCGCCCCGCTTCGCGGCGCTTGC
AGTGCCACTAGGCTGGCGTC

Downstream 100 bases:

>100_bases
CCGCCGTGCGCTGGCACCTACGCGGTCGGAGTCTGCCCGACGAGGGCCCGATCGAACTCTGGGTCGTCGACGGGCGGATC
AGCACCGAACCGGTGGCCGG

Product: hypothetical protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MFESLSDRLTGALAGLRGKGRLTDADIEATTREIRLALLEADVSLPVVRAFVTRIKERAKGAEVSGALNPAQQVVKIVNE
ELIGILGGETRQLAFAKTPPTVIMLAGLQGSGKTSLAGKLAAWLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFA
PHPGASPESGPGDPVAVAAQGLAEARAKHHDVVIVDTAGRLGIDDELMAQAAAIRDAIDPDEILFVLDAMIGQDAVTTAE
AFREGVGFTGVVLTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMSSRILGMGDVLSLIEQAEQVFDAE
QAEAAAVKIGSGELTLEDFLEQMLAIRKMGPIGNLLGMLPGAGQMKDALAAVDDKQLDRLQAIIRGMTPEERADPKIINA
SRRLRIANGSGVTVSEVNQLVDRFFEARKMMSSMLGGMGIPGLGRKSATRKAKGAKGKAKKGKKGARGPTPPEVRSPLGP
GMPAGFPDLSQLPEGLNELPPGLADFDLSKLKFPGNK

Sequences:

>Translated_517_residues
MFESLSDRLTGALAGLRGKGRLTDADIEATTREIRLALLEADVSLPVVRAFVTRIKERAKGAEVSGALNPAQQVVKIVNE
ELIGILGGETRQLAFAKTPPTVIMLAGLQGSGKTSLAGKLAAWLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFA
PHPGASPESGPGDPVAVAAQGLAEARAKHHDVVIVDTAGRLGIDDELMAQAAAIRDAIDPDEILFVLDAMIGQDAVTTAE
AFREGVGFTGVVLTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMSSRILGMGDVLSLIEQAEQVFDAE
QAEAAAVKIGSGELTLEDFLEQMLAIRKMGPIGNLLGMLPGAGQMKDALAAVDDKQLDRLQAIIRGMTPEERADPKIINA
SRRLRIANGSGVTVSEVNQLVDRFFEARKMMSSMLGGMGIPGLGRKSATRKAKGAKGKAKKGKKGARGPTPPEVRSPLGP
GMPAGFPDLSQLPEGLNELPPGLADFDLSKLKFPGNK
>Mature_517_residues
MFESLSDRLTGALAGLRGKGRLTDADIEATTREIRLALLEADVSLPVVRAFVTRIKERAKGAEVSGALNPAQQVVKIVNE
ELIGILGGETRQLAFAKTPPTVIMLAGLQGSGKTSLAGKLAAWLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFA
PHPGASPESGPGDPVAVAAQGLAEARAKHHDVVIVDTAGRLGIDDELMAQAAAIRDAIDPDEILFVLDAMIGQDAVTTAE
AFREGVGFTGVVLTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMSSRILGMGDVLSLIEQAEQVFDAE
QAEAAAVKIGSGELTLEDFLEQMLAIRKMGPIGNLLGMLPGAGQMKDALAAVDDKQLDRLQAIIRGMTPEERADPKIINA
SRRLRIANGSGVTVSEVNQLVDRFFEARKMMSSMLGGMGIPGLGRKSATRKAKGAKGKAKKGKKGARGPTPPEVRSPLGP
GMPAGFPDLSQLPEGLNELPPGLADFDLSKLKFPGNK

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=445, Percent_Identity=32.3595505617978, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI226371618, Length=387, Percent_Identity=33.0749354005168, Blast_Score=215, Evalue=6e-56,
Organism=Homo sapiens, GI89061728, Length=159, Percent_Identity=38.9937106918239, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI23308697, Length=309, Percent_Identity=30.0970873786408, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI295424842, Length=309, Percent_Identity=30.0970873786408, Blast_Score=114, Evalue=3e-25,
Organism=Escherichia coli, GI1788963, Length=427, Percent_Identity=49.8829039812646, Blast_Score=407, Evalue=1e-114,
Organism=Escherichia coli, GI1789874, Length=271, Percent_Identity=36.90036900369, Blast_Score=155, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI17539958, Length=427, Percent_Identity=29.9765807962529, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=29.8657718120805, Blast_Score=104, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=490, Percent_Identity=32.8571428571429, Blast_Score=239, Evalue=8e-64,
Organism=Saccharomyces cerevisiae, GI6320498, Length=213, Percent_Identity=31.4553990610329, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17647949, Length=445, Percent_Identity=30.1123595505618, Blast_Score=205, Evalue=7e-53,
Organism=Drosophila melanogaster, GI24641198, Length=309, Percent_Identity=27.5080906148867, Blast_Score=106, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 54269; Mature: 54269

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFESLSDRLTGALAGLRGKGRLTDADIEATTREIRLALLEADVSLPVVRAFVTRIKERAK
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GAEVSGALNPAQQVVKIVNEELIGILGGETRQLAFAKTPPTVIMLAGLQGSGKTSLAGKL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHH
AAWLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFAPHPGASPESGPGDPVAVAAQ
HHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHH
GLAEARAKHHDVVIVDTAGRLGIDDELMAQAAAIRDAIDPDEILFVLDAMIGQDAVTTAE
HHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
AFREGVGFTGVVLTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMSSRI
HHHHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCHHHCCCCCCHHHHHHH
LGMGDVLSLIEQAEQVFDAEQAEAAAVKIGSGELTLEDFLEQMLAIRKMGPIGNLLGMLP
CCHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHCCC
GAGQMKDALAAVDDKQLDRLQAIIRGMTPEERADPKIINASRRLRIANGSGVTVSEVNQL
CCCHHHHHHHHHCHHHHHHHHHHHHCCCCCHHCCCCEECCCCEEEEECCCCCCHHHHHHH
VDRFFEARKMMSSMLGGMGIPGLGRKSATRKAKGAKGKAKKGKKGARGPTPPEVRSPLGP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCC
GMPAGFPDLSQLPEGLNELPPGLADFDLSKLKFPGNK
CCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MFESLSDRLTGALAGLRGKGRLTDADIEATTREIRLALLEADVSLPVVRAFVTRIKERAK
CCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHC
GAEVSGALNPAQQVVKIVNEELIGILGGETRQLAFAKTPPTVIMLAGLQGSGKTSLAGKL
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCHHHHHHH
AAWLRGQGHTPLLVACDLQRPAAVNQLQVVGERAGVPVFAPHPGASPESGPGDPVAVAAQ
HHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCHHHHHHH
GLAEARAKHHDVVIVDTAGRLGIDDELMAQAAAIRDAIDPDEILFVLDAMIGQDAVTTAE
HHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHH
AFREGVGFTGVVLTKLDGDARGGAALSVREVTGVPILFASTGEKLEDFDVFHPDRMSSRI
HHHHCCCCCEEEEEEECCCCCCCCEEEEEECCCCCEEEECCCCCHHHCCCCCCHHHHHHH
LGMGDVLSLIEQAEQVFDAEQAEAAAVKIGSGELTLEDFLEQMLAIRKMGPIGNLLGMLP
CCHHHHHHHHHHHHHHHCHHHHHHEEEEECCCCEEHHHHHHHHHHHHHCCCHHHHHHCCC
GAGQMKDALAAVDDKQLDRLQAIIRGMTPEERADPKIINASRRLRIANGSGVTVSEVNQL
CCCHHHHHHHHHCHHHHHHHHHHHHCCCCCHHCCCCEECCCCEEEEECCCCCCHHHHHHH
VDRFFEARKMMSSMLGGMGIPGLGRKSATRKAKGAKGKAKKGKKGARGPTPPEVRSPLGP
HHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHCCCCC
GMPAGFPDLSQLPEGLNELPPGLADFDLSKLKFPGNK
CCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]