| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG
Identifier: 41408970
GI number: 41408970
Start: 3199078
End: 3199857
Strand: Reverse
Name: fabG
Synonym: MAP2872c
Alternate gene names: 41408970
Gene position: 3199857-3199078 (Counterclockwise)
Preceding gene: 41408971
Following gene: 41408969
Centisome position: 66.25
GC content: 71.54
Gene sequence:
>780_bases ATGACCTCACAGGATCTGACCGGACGCACCGCCATCATCACCGGCGCGTCGCGCGGTATCGGGCTGGCCATCGCCCAGCA GCTGGCCGCGGCGGGCGCCAACGTGGTGCTCACCGCCCGCAAGCAGGAGGCCGCCGACGAGGCCGCCGCCCAGGTGGGGC CGCAGGCCCTCGGGGTCGGTGCCCACGCGGTCGACGAGGACGCGGCCCGCCAGTGCGTGCAGCTCACGCTGGAGCGCTTC GGCAGCGTCGACATCCTGGTCAACAACGCCGGGACGAATCCGGCGTACGGGCCGCTGATCGAGCAGGACCACGCCCGGTT TGCCAAGATCTTCGACGTCAACCTGTGGGCGCCGCTGCTGTGGACCTCGCTGGCGGTCAAGTCGTGGATGGGCGAACACG GCGGCTCGATCGTCAACACGGCCTCCATCGGCGGCCTGCACCAGTCGCCGGCAATGGGCATGTACAACGCCACCAAGGCG GCGCTGATCCACGTCACCAAGCAACTGGCGCTGGAACTTTCGCCGCGCGTCCGGGTCAACGCGATCGCCCCCGGGGTGGT GCGCACCCGGCTCGCCGAGGCGCTGTGGAAGGACCACGAGGACCCGCTGTCGTCCTCGATCGCGCTGGGCCGCATCGGCG AGCCGATCGACGTGGCCGCCGCCGTCGCCTTCCTGGTGTCCGACGCCGCCAGCTGGATCACCGGCGAGACACTGGTCATC GACGGCGGCACCGTGCTCGGCGCCGCGCAGGGATTCCGGCCGGCGCCGACGCCGTCCTGA
Upstream 100 bases:
>100_bases ATGCGGCTGGCATACCACCTCAACACCTGTCCAAAACATCGCGAATAAAATTTCGGCAGCAAACGAACGACCGGCCCACC ACCGCGACAGAAGGCACACC
Downstream 100 bases:
>100_bases CCGGGCCGCGGCGACGCTAGAGTTTCCCGACCACACCTTGAAGGCGGGAACCAGCGGATGCGTGTGCTGCTGTCGGCGTA CGACTCGCGCGGCGGGGTGC
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 259; Mature: 258
Protein sequence:
>259_residues MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVLTARKQEAADEAAAQVGPQALGVGAHAVDEDAARQCVQLTLERF GSVDILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEHGGSIVNTASIGGLHQSPAMGMYNATKA ALIHVTKQLALELSPRVRVNAIAPGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWITGETLVI DGGTVLGAAQGFRPAPTPS
Sequences:
>Translated_259_residues MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVLTARKQEAADEAAAQVGPQALGVGAHAVDEDAARQCVQLTLERF GSVDILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEHGGSIVNTASIGGLHQSPAMGMYNATKA ALIHVTKQLALELSPRVRVNAIAPGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWITGETLVI DGGTVLGAAQGFRPAPTPS >Mature_258_residues TSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVLTARKQEAADEAAAQVGPQALGVGAHAVDEDAARQCVQLTLERFG SVDILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGEHGGSIVNTASIGGLHQSPAMGMYNATKAA LIHVTKQLALELSPRVRVNAIAPGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWITGETLVID GGTVLGAAQGFRPAPTPS
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI32483357, Length=251, Percent_Identity=39.4422310756972, Blast_Score=181, Evalue=5e-46, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=36.8421052631579, Blast_Score=151, Evalue=5e-37, Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=33.8582677165354, Blast_Score=138, Evalue=4e-33, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=35.1464435146443, Blast_Score=133, Evalue=2e-31, Organism=Homo sapiens, GI33667109, Length=194, Percent_Identity=36.5979381443299, Blast_Score=124, Evalue=9e-29, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=34.7490347490347, Blast_Score=122, Evalue=3e-28, Organism=Homo sapiens, GI126723191, Length=187, Percent_Identity=36.8983957219251, Blast_Score=117, Evalue=9e-27, Organism=Homo sapiens, GI7705925, Length=245, Percent_Identity=34.6938775510204, Blast_Score=111, Evalue=6e-25, Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=36, Blast_Score=106, Evalue=2e-23, Organism=Homo sapiens, GI31542939, Length=244, Percent_Identity=29.5081967213115, Blast_Score=92, Evalue=7e-19, Organism=Homo sapiens, GI4758504, Length=254, Percent_Identity=28.740157480315, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI10190704, Length=260, Percent_Identity=30, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI15277342, Length=252, Percent_Identity=31.7460317460317, Blast_Score=89, Evalue=5e-18, Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI302344755, Length=109, Percent_Identity=37.6146788990826, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI109715829, Length=242, Percent_Identity=29.7520661157025, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI224922801, Length=173, Percent_Identity=30.0578034682081, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI7657478, Length=199, Percent_Identity=32.6633165829146, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI32455239, Length=165, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI5031765, Length=165, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI20149619, Length=224, Percent_Identity=29.4642857142857, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI226371731, Length=191, Percent_Identity=27.2251308900524, Blast_Score=65, Evalue=4e-11, Organism=Escherichia coli, GI1787335, Length=243, Percent_Identity=34.9794238683128, Blast_Score=136, Evalue=2e-33, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=36.2204724409449, Blast_Score=125, Evalue=2e-30, Organism=Escherichia coli, GI1787905, Length=246, Percent_Identity=33.3333333333333, Blast_Score=113, Evalue=1e-26, Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=33.7209302325581, Blast_Score=109, Evalue=1e-25, Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=32.2834645669291, Blast_Score=102, Evalue=2e-23, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=34.0248962655602, Blast_Score=101, Evalue=4e-23, Organism=Escherichia coli, GI1790717, Length=247, Percent_Identity=28.3400809716599, Blast_Score=99, Evalue=3e-22, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=28.6290322580645, Blast_Score=95, Evalue=5e-21, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=29.6, Blast_Score=94, Evalue=9e-21, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=31.9230769230769, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI2367175, Length=250, Percent_Identity=32, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787526, Length=251, Percent_Identity=27.4900398406374, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1786701, Length=201, Percent_Identity=28.8557213930348, Blast_Score=67, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17561402, Length=248, Percent_Identity=40.3225806451613, Blast_Score=181, Evalue=2e-46, Organism=Caenorhabditis elegans, GI17560676, Length=244, Percent_Identity=40.5737704918033, Blast_Score=176, Evalue=1e-44, Organism=Caenorhabditis elegans, GI17562906, Length=262, Percent_Identity=32.4427480916031, Blast_Score=124, Evalue=5e-29, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=36.1788617886179, Blast_Score=122, Evalue=2e-28, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=31.9548872180451, Blast_Score=119, Evalue=1e-27, Organism=Caenorhabditis elegans, GI72000259, Length=260, Percent_Identity=35.3846153846154, Blast_Score=119, Evalue=2e-27, Organism=Caenorhabditis elegans, GI17562908, Length=262, Percent_Identity=33.206106870229, Blast_Score=117, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17563726, Length=260, Percent_Identity=33.4615384615385, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17560332, Length=267, Percent_Identity=35.5805243445693, Blast_Score=112, Evalue=3e-25, Organism=Caenorhabditis elegans, GI17531453, Length=262, Percent_Identity=31.6793893129771, Blast_Score=111, Evalue=5e-25, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=33.0677290836653, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=33.976833976834, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI17560150, Length=260, Percent_Identity=33.8461538461538, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=31.5789473684211, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=34.6774193548387, Blast_Score=107, Evalue=8e-24, Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=32.0610687022901, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=34.6774193548387, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=32.824427480916, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=33.2089552238806, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=29.6992481203008, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17538480, Length=263, Percent_Identity=31.9391634980989, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=34.5679012345679, Blast_Score=101, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17565030, Length=266, Percent_Identity=32.7067669172932, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17508651, Length=247, Percent_Identity=28.7449392712551, Blast_Score=97, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=29.4776119402985, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI17538182, Length=249, Percent_Identity=28.9156626506024, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17555612, Length=273, Percent_Identity=32.2344322344322, Blast_Score=82, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17561272, Length=250, Percent_Identity=30, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17536025, Length=252, Percent_Identity=29.7619047619048, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17536651, Length=254, Percent_Identity=28.740157480315, Blast_Score=74, Evalue=8e-14, Organism=Caenorhabditis elegans, GI17558006, Length=208, Percent_Identity=27.8846153846154, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17508895, Length=246, Percent_Identity=26.8292682926829, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI71997099, Length=209, Percent_Identity=31.1004784688995, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI25152911, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=6e-12, Organism=Caenorhabditis elegans, GI71982365, Length=95, Percent_Identity=40, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=260, Percent_Identity=27.3076923076923, Blast_Score=85, Evalue=1e-17, Organism=Saccharomyces cerevisiae, GI6323882, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=5e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=205, Percent_Identity=28.780487804878, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6322067, Length=192, Percent_Identity=30.7291666666667, Blast_Score=70, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=26.3440860215054, Blast_Score=65, Evalue=8e-12, Organism=Saccharomyces cerevisiae, GI6319635, Length=188, Percent_Identity=30.8510638297872, Blast_Score=64, Evalue=3e-11, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=39.1129032258064, Blast_Score=173, Evalue=1e-43, Organism=Drosophila melanogaster, GI24644337, Length=250, Percent_Identity=36.4, Blast_Score=128, Evalue=4e-30, Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=37.3493975903614, Blast_Score=127, Evalue=5e-30, Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=36.1788617886179, Blast_Score=126, Evalue=2e-29, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=38.8663967611336, Blast_Score=124, Evalue=4e-29, Organism=Drosophila melanogaster, GI24644339, Length=252, Percent_Identity=36.5079365079365, Blast_Score=123, Evalue=9e-29, Organism=Drosophila melanogaster, GI24643142, Length=248, Percent_Identity=36.6935483870968, Blast_Score=118, Evalue=4e-27, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=31.3008130081301, Blast_Score=99, Evalue=3e-21, Organism=Drosophila melanogaster, GI17737361, Length=246, Percent_Identity=28.4552845528455, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=30.3482587064677, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI116007234, Length=239, Percent_Identity=28.8702928870293, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24580925, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24584744, Length=197, Percent_Identity=28.4263959390863, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI28574402, Length=197, Percent_Identity=28.4263959390863, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI24649181, Length=195, Percent_Identity=28.2051282051282, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI161076933, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24584748, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=27.0935960591133, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 26793; Mature: 26662
Theoretical pI: Translated: 5.93; Mature: 5.93
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVLTARKQEAADEAAAQVGPQALGVG CCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCHHHCCC AHAVDEDAARQCVQLTLERFGSVDILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLL CHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH WTSLAVKSWMGEHGGSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPRVRVN HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE AIAPGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWITGETLVI EECCHHHHHHHHHHHHCCCCCCHHHCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE DGGTVLGAAQGFRPAPTPS ECCEEEECCCCCCCCCCCC >Mature Secondary Structure TSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVLTARKQEAADEAAAQVGPQALGVG CCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHCCCHHHCCC AHAVDEDAARQCVQLTLERFGSVDILVNNAGTNPAYGPLIEQDHARFAKIFDVNLWAPLL CHHCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHH WTSLAVKSWMGEHGGSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPRVRVN HHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE AIAPGVVRTRLAEALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAASWITGETLVI EECCHHHHHHHHHHHHCCCCCCHHHCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEE DGGTVLGAAQGFRPAPTPS ECCEEEECCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8759840; 9384377; 9534248; 8654983 [H]