BacMap

Definition	Mycobacterium avium subsp. paratuberculosis K-10, complete genome.
Accession	NC_002944
Length	4,829,781

Click here to switch to the map view.

The map label for this gene is ucpA [C]

Identifier: 41408959

GI number: 41408959

Start: 3188331

End: 3189161

Strand: Direct

Name: ucpA [C]

Synonym: MAP2861

Alternate gene names: 41408959

Gene position: 3188331-3189161 (Clockwise)

Preceding gene: 41408958

Following gene: 41408960

Centisome position: 66.01

GC content: 69.43

Gene sequence:

>831_bases
ATGCCCCGCTCGTCGGAAGGGCCCCTGACGGGAAAGGTCGCCTTCATCACCGGCGCGGCGCGCGGTCAGGGGCGCGCGCA
CGCGGTGCGGCTGGCCGCCGACGGCGCCGACATCATCGCCGTCGACCTGTGTGACCAGATCGCCAGCGTGCCCTACCCGC
TGGCCACCCCCGAGGAGCTGGCGGCCACGGTGAAGCTGGTGGAGGACATCGGCTCGCGCATCGTGGCCAGGCAGGCCGAC
GTGCGTGACCGGGAATCCCTGTCGGCGGCGCTGCAGGCGGGTCTCGACGAGTTGGGCCGCCTGGACATCGTGGTGGCCAA
CGCCGGCATCGCGCCCATGTCCGCCGGTGACGACGGCTGGCACGACGTGATCGACGTCAACCTCACCGGCGTCTACCACA
CCATCAAGGTCGCGATCCCGACCCTGGTCAAACAGGGCACCGGCGGGTCGATCGTGCTGATCAGTTCGAGCGCCGGACTG
GCCGGCGTCGGCAGCGCGGACCCGGGTTCGGTCGGCTACGTCGCCGCCAAGCACGGGGTGGTGGGGTTGATGCGGGTATA
CGCGAATCTGCTTGCCGGGCAGATGATCCGGGTGAACTCGATTCATCCCTCCGGGGTGGAGACGCCGATGATCAACAACG
AGTTCACCCGGGAGTGGCTGGCCAAGATGGCCGCCGCGACCGACACGCCGGGGGCGATGGGCAATGCCATGCCGGTGGAG
GTGCTCGCCCCCGAAGACGTCGCCAACGCGGTGGCGTGGTTGGTGTCCGACCAGGCCCGCTACATCACCGGCGTCACCCT
GCCGGTGGACGCGGGCTTTTTGAACAAGTAG

Upstream 100 bases:

>100_bases
TGTTCAGCGCGGCCGGCGAGCACCTCGACGGCGCCCCGGACATCAAGATGTTGCAGCCGGTTCCGGCCGGCGACCCGGGC
AAGGGACAGTTGCGTCCCTG

Downstream 100 bases:

>100_bases
CGGCCATGGCACGAAATCCGGTAGCGCAGACGGCATTTGGGCCGATGGTGTTGGCGGCGGTCGAGCAGAATGAGCCGCCC
GGCCGCCGTTTGGTGGACGA

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MPRSSEGPLTGKVAFITGAARGQGRAHAVRLAADGADIIAVDLCDQIASVPYPLATPEELAATVKLVEDIGSRIVARQAD
VRDRESLSAALQAGLDELGRLDIVVANAGIAPMSAGDDGWHDVIDVNLTGVYHTIKVAIPTLVKQGTGGSIVLISSSAGL
AGVGSADPGSVGYVAAKHGVVGLMRVYANLLAGQMIRVNSIHPSGVETPMINNEFTREWLAKMAAATDTPGAMGNAMPVE
VLAPEDVANAVAWLVSDQARYITGVTLPVDAGFLNK

Sequences:

>Translated_276_residues
MPRSSEGPLTGKVAFITGAARGQGRAHAVRLAADGADIIAVDLCDQIASVPYPLATPEELAATVKLVEDIGSRIVARQAD
VRDRESLSAALQAGLDELGRLDIVVANAGIAPMSAGDDGWHDVIDVNLTGVYHTIKVAIPTLVKQGTGGSIVLISSSAGL
AGVGSADPGSVGYVAAKHGVVGLMRVYANLLAGQMIRVNSIHPSGVETPMINNEFTREWLAKMAAATDTPGAMGNAMPVE
VLAPEDVANAVAWLVSDQARYITGVTLPVDAGFLNK
>Mature_275_residues
PRSSEGPLTGKVAFITGAARGQGRAHAVRLAADGADIIAVDLCDQIASVPYPLATPEELAATVKLVEDIGSRIVARQADV
RDRESLSAALQAGLDELGRLDIVVANAGIAPMSAGDDGWHDVIDVNLTGVYHTIKVAIPTLVKQGTGGSIVLISSSAGLA
GVGSADPGSVGYVAAKHGVVGLMRVYANLLAGQMIRVNSIHPSGVETPMINNEFTREWLAKMAAATDTPGAMGNAMPVEV
LAPEDVANAVAWLVSDQARYITGVTLPVDAGFLNK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI15277342, Length=286, Percent_Identity=32.8671328671329, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI32483357, Length=272, Percent_Identity=31.6176470588235, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI31542939, Length=256, Percent_Identity=31.25, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI19923817, Length=273, Percent_Identity=28.5714285714286, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI224922801, Length=190, Percent_Identity=33.6842105263158, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4504505, Length=278, Percent_Identity=31.294964028777, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126723750, Length=272, Percent_Identity=28.3088235294118, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI7705925, Length=270, Percent_Identity=28.5185185185185, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI40254992, Length=267, Percent_Identity=29.9625468164794, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI126723191, Length=200, Percent_Identity=32, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI40254986, Length=204, Percent_Identity=31.3725490196078, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI59889578, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=222, Percent_Identity=27.027027027027, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI10190704, Length=269, Percent_Identity=27.5092936802974, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI5031737, Length=273, Percent_Identity=27.4725274725275, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082100, Length=276, Percent_Identity=35.1449275362319, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1787335, Length=270, Percent_Identity=34.0740740740741, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789208, Length=272, Percent_Identity=30.1470588235294, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1788459, Length=268, Percent_Identity=29.8507462686567, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787905, Length=276, Percent_Identity=28.2608695652174, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082160, Length=277, Percent_Identity=27.0758122743682, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1790717, Length=274, Percent_Identity=29.1970802919708, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI2367175, Length=275, Percent_Identity=28.3636363636364, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786812, Length=273, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787526, Length=285, Percent_Identity=27.3684210526316, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788891, Length=234, Percent_Identity=27.3504273504274, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=276, Percent_Identity=30.7971014492754, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17555706, Length=271, Percent_Identity=32.4723247232472, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25147288, Length=270, Percent_Identity=30.3703703703704, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=274, Percent_Identity=32.1167883211679, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17560332, Length=281, Percent_Identity=31.6725978647687, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17561402, Length=281, Percent_Identity=28.1138790035587, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538480, Length=279, Percent_Identity=29.0322580645161, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=213, Percent_Identity=29.1079812206573, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=291, Percent_Identity=27.1477663230241, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=285, Percent_Identity=27.719298245614, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=278, Percent_Identity=31.294964028777, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538486, Length=276, Percent_Identity=29.3478260869565, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=285, Percent_Identity=24.5614035087719, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=179, Percent_Identity=29.0502793296089, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538182, Length=277, Percent_Identity=27.0758122743682, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=285, Percent_Identity=28.4210526315789, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=177, Percent_Identity=29.3785310734463, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71982365, Length=262, Percent_Identity=24.4274809160305, Blast_Score=64, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324126, Length=272, Percent_Identity=27.5735294117647, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24644339, Length=277, Percent_Identity=32.8519855595668, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639444, Length=280, Percent_Identity=30.3571428571429, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI28571526, Length=268, Percent_Identity=31.7164179104478, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355319, Length=267, Percent_Identity=29.9625468164794, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI17737361, Length=227, Percent_Identity=31.7180616740088, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=274, Percent_Identity=29.1970802919708, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI23397609, Length=277, Percent_Identity=32.129963898917, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859837, Length=235, Percent_Identity=29.7872340425532, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640492, Length=217, Percent_Identity=26.7281105990783, Blast_Score=71, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21357673, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364892, Length=223, Percent_Identity=26.457399103139, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24663911, Length=255, Percent_Identity=25.8823529411765, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007236, Length=260, Percent_Identity=26.5384615384615, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28424; Mature: 28293

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRSSEGPLTGKVAFITGAARGQGRAHAVRLAADGADIIAVDLCDQIASVPYPLATPEEL
CCCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEHHHHHHHHCCCCCCCHHHH
AATVKLVEDIGSRIVARQADVRDRESLSAALQAGLDELGRLDIVVANAGIAPMSAGDDGW
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHCCEEEEEECCCCCCCCCCCCCC
HDVIDVNLTGVYHTIKVAIPTLVKQGTGGSIVLISSSAGLAGVGSADPGSVGYVAAKHGV
CEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEHHHHH
VGLMRVYANLLAGQMIRVNSIHPSGVETPMINNEFTREWLAKMAAATDTPGAMGNAMPVE
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLAPEDVANAVAWLVSDQARYITGVTLPVDAGFLNK
EECCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure 
PRSSEGPLTGKVAFITGAARGQGRAHAVRLAADGADIIAVDLCDQIASVPYPLATPEEL
CCCCCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCEEEEHHHHHHHHCCCCCCCHHHH
AATVKLVEDIGSRIVARQADVRDRESLSAALQAGLDELGRLDIVVANAGIAPMSAGDDGW
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCHHHHCCEEEEEECCCCCCCCCCCCCC
HDVIDVNLTGVYHTIKVAIPTLVKQGTGGSIVLISSSAGLAGVGSADPGSVGYVAAKHGV
CEEEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEHHHHH
VGLMRVYANLLAGQMIRVNSIHPSGVETPMINNEFTREWLAKMAAATDTPGAMGNAMPVE
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEE
VLAPEDVANAVAWLVSDQARYITGVTLPVDAGFLNK
EECCHHHHHHHHHHHCCCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA