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The map label for this gene is fabG5_1

Identifier: 41408834

GI number: 41408834

Start: 3069407

End: 3070201

Strand: Direct

Name: fabG5_1

Synonym: MAP2736

Alternate gene names: 41408834

Gene position: 3069407-3070201 (Clockwise)

Preceding gene: 41408833

Following gene: 41408835

Centisome position: 63.55

GC content: 73.46

Gene sequence:

>795_bases
ATGACCGGCTGGCTTGACGGCAAGCGCGCCCTCGTCGTCGGCGCGGGGTCGGGAATCGGGCGCGCCGTCGTCGACGCCTT
CGCCGCCGAGGGCGCGAAAGTCGCTGCGCTGGAACGCGATAGCGACAAGTGCGACCGGCTGCGCCGGCAGCTGCCCGAGG
TGGCCGTCGCCGAGGGCGACGCCACCACCCGCCAGGCCAACGAACGGGCCGTGGCGCTCGCGGTGGACACCTTCGGCGGG
CTGGACACCCTGGTCAACTGCGTCGGGGTGTTCGACTTCTACCGCGGGGTGGCCGACATCGACGCGGGCGCGCTCGCCGA
CGCGTTCGACGAGATGTTTCGCACCAACGTGCTGAGCCACCTGCAGTCGGTTAAGGCGGCGCTGCCCGCGCTGCGGGCCG
CCGGTGCTTCCTCGATCGTGCTGACCGAGTCCGCATCGTCGTTCTATCCGGGCCGCGGCGGGGTGCTCTACGTGTCGTCG
AAATTCGCGGTGCGCGGGCTGGTTTCGGCGTTGGCGCACGAGCTGGCGCCGGGGATCCGGGTCAACGGCGTGGCCCCGGG
CGGCACGCTGGGCACCGACCTGCGCGGCCTGGCCAGCCTGGGGCTGCAGGGCACCCGCCTGGACGACGCCCCGGACCGGG
CGGCCGAGGTGGCCGCCCGCACTCCCCTGCGGGTCGCGCTGTCCGGCGCCGACCATGCCTGGAGTTTCGTGTTCCTGGCC
TCCGACCGGTCCCGCGGCATCACCGGCGAAACCGTAAGGCCCGACGGCGGATTCGGGCTGGGGACGCCCCGGTGA

Upstream 100 bases:

>100_bases
CTGGAGGTCGAGGCGCTGACCTGGCAGAACCCCCGCACGCTGGCCGCCATGGTGGGCAACGGCCAGGCGCCGCTGCTGCC
CGACGAACCGGAGGACGGCG

Downstream 100 bases:

>100_bases
GCGGCCGGCTGGACGAGCAGCGCGCCCTGGTGGCGCAGGGCTGCCGGATGGCGGCGGCCCGCGGCCTGGTCGACGGCATC
CTCGGGCATGTGAGCCTGCG

Product: 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase

Products: NA

Alternate protein names: Cis-benzene glycol dehydrogenase [H]

Number of amino acids: Translated: 264; Mature: 263

Protein sequence:

>264_residues
MTGWLDGKRALVVGAGSGIGRAVVDAFAAEGAKVAALERDSDKCDRLRRQLPEVAVAEGDATTRQANERAVALAVDTFGG
LDTLVNCVGVFDFYRGVADIDAGALADAFDEMFRTNVLSHLQSVKAALPALRAAGASSIVLTESASSFYPGRGGVLYVSS
KFAVRGLVSALAHELAPGIRVNGVAPGGTLGTDLRGLASLGLQGTRLDDAPDRAAEVAARTPLRVALSGADHAWSFVFLA
SDRSRGITGETVRPDGGFGLGTPR

Sequences:

>Translated_264_residues
MTGWLDGKRALVVGAGSGIGRAVVDAFAAEGAKVAALERDSDKCDRLRRQLPEVAVAEGDATTRQANERAVALAVDTFGG
LDTLVNCVGVFDFYRGVADIDAGALADAFDEMFRTNVLSHLQSVKAALPALRAAGASSIVLTESASSFYPGRGGVLYVSS
KFAVRGLVSALAHELAPGIRVNGVAPGGTLGTDLRGLASLGLQGTRLDDAPDRAAEVAARTPLRVALSGADHAWSFVFLA
SDRSRGITGETVRPDGGFGLGTPR
>Mature_263_residues
TGWLDGKRALVVGAGSGIGRAVVDAFAAEGAKVAALERDSDKCDRLRRQLPEVAVAEGDATTRQANERAVALAVDTFGGL
DTLVNCVGVFDFYRGVADIDAGALADAFDEMFRTNVLSHLQSVKAALPALRAAGASSIVLTESASSFYPGRGGVLYVSSK
FAVRGLVSALAHELAPGIRVNGVAPGGTLGTDLRGLASLGLQGTRLDDAPDRAAEVAARTPLRVALSGADHAWSFVFLAS
DRSRGITGETVRPDGGFGLGTPR

Specific function: Converts Cis-3-(3-Carboxyethyl)-3,5-Cyclohexadiene-1,2- Diol (Pp-Dihydrodiol) Into 3-(2,3-Dihydroxylphenyl)Propionate (Dhpp). [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=266, Percent_Identity=31.203007518797, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI7705925, Length=263, Percent_Identity=33.4600760456274, Blast_Score=88, Evalue=7e-18,
Organism=Homo sapiens, GI126723191, Length=211, Percent_Identity=32.2274881516588, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4504505, Length=199, Percent_Identity=30.6532663316583, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI33667109, Length=272, Percent_Identity=29.4117647058824, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788891, Length=241, Percent_Identity=37.344398340249, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1789378, Length=267, Percent_Identity=29.9625468164794, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082160, Length=258, Percent_Identity=27.5193798449612, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787905, Length=263, Percent_Identity=26.615969581749, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787335, Length=261, Percent_Identity=29.8850574712644, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI87082100, Length=271, Percent_Identity=29.8892988929889, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=263, Percent_Identity=31.5589353612167, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=270, Percent_Identity=27.4074074074074, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=261, Percent_Identity=27.9693486590038, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=29.1044776119403, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=27.536231884058, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=272, Percent_Identity=28.3088235294118, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17562908, Length=197, Percent_Identity=28.9340101522843, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=274, Percent_Identity=26.6423357664234, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=27.3408239700375, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=27.8388278388278, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=27.5092936802974, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=271, Percent_Identity=28.7822878228782, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=280, Percent_Identity=26.4285714285714, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=280, Percent_Identity=25.7142857142857, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=280, Percent_Identity=26.4285714285714, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=188, Percent_Identity=27.6595744680851, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=271, Percent_Identity=28.4132841328413, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=266, Percent_Identity=30.4511278195489, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=28.957528957529, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24644339, Length=273, Percent_Identity=27.8388278388278, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28571526, Length=281, Percent_Identity=29.1814946619217, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017711
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.3.1.19 [H]

Molecular weight: Translated: 27195; Mature: 27064

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGWLDGKRALVVGAGSGIGRAVVDAFAAEGAKVAALERDSDKCDRLRRQLPEVAVAEGD
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCHHEECCCC
ATTRQANERAVALAVDTFGGLDTLVNCVGVFDFYRGVADIDAGALADAFDEMFRTNVLSH
CHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LQSVKAALPALRAAGASSIVLTESASSFYPGRGGVLYVSSKFAVRGLVSALAHELAPGIR
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCE
VNGVAPGGTLGTDLRGLASLGLQGTRLDDAPDRAAEVAARTPLRVALSGADHAWSFVFLA
EECCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEEEE
SDRSRGITGETVRPDGGFGLGTPR
CCCCCCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
TGWLDGKRALVVGAGSGIGRAVVDAFAAEGAKVAALERDSDKCDRLRRQLPEVAVAEGD
CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCHHEECCCC
ATTRQANERAVALAVDTFGGLDTLVNCVGVFDFYRGVADIDAGALADAFDEMFRTNVLSH
CHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LQSVKAALPALRAAGASSIVLTESASSFYPGRGGVLYVSSKFAVRGLVSALAHELAPGIR
HHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHCCCCE
VNGVAPGGTLGTDLRGLASLGLQGTRLDDAPDRAAEVAARTPLRVALSGADHAWSFVFLA
EECCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCEEEEECCCCCCEEEEEEE
SDRSRGITGETVRPDGGFGLGTPR
CCCCCCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3667527 [H]