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The map label for this gene is engD [H]

Identifier: 41408780

GI number: 41408780

Start: 3017001

End: 3018074

Strand: Reverse

Name: engD [H]

Synonym: MAP2682c

Alternate gene names: 41408780

Gene position: 3018074-3017001 (Counterclockwise)

Preceding gene: 41408782

Following gene: 41408779

Centisome position: 62.49

GC content: 67.32

Gene sequence:

>1074_bases
GTGAGCCTGAGCCTGGGAATAGTGGGCCTGCCCAACGTCGGCAAGTCGACCTTGTTCAACGCGTTGACCCGGAACAACGT
GGTCGCGGCCAACTATCCGTTCGCGACGATCGAGCCCAACGAGGGCGTGGTGCCGCTGCCCGACCCGCGGCTGGACAAGC
TGGCCGAGATGTTCAAGTCCGAGCGCATCGTGGCGGCGCCGGTCACCTTCGTCGACATCGCCGGCCTGGTCAAGGGCGCC
TCCGAGGGGGCGGGGCTGGGCAACAAGTTCCTGGCCCACATTCGCGAATGCGACGCCATCTGCCAGGTGGTGCGGGTGTT
CGCCGACGACGACGTCACCCACGTCGCCGGTCAGGTGGACCCCAGGTCCGACATCGAGGTCGTCGAGACCGAGCTGATCC
TGGCCGACCTGCAGACGCTGGAGCGCGCGGTGGGCCGGCTGGAGAAGGAGGCCCGCACCTCCAAGGAGCGCCGGCCGGTC
TACGAGGCGGCGCTGGCCGCGCAGGAGACGCTGAACGGGGGCAAGACGCTGTTCAGCGCGGGCACCGACACCTCCCTGCT
GCGCGAGCTGAACCTGTTGACCACCAAGCCTTTTCTCTATGTCTTCAACGCCGACGAGTCGGTGCTGACCGATCCCGCGC
GCATCGCCGAGCTGCGCGAGCTGGTCGCGCCGGCCGACGCGGTGTTCCTGGACGCGGCCATCGAATCCGAGCTGATCGAA
CTCGACGACGAGTCGGCGGCGGAGTTGCTGGAGTCGATCGGGCAGACCGAGCGCGGCCTGGATGCGTTGGCGCGGGCCGG
TTTTCACACGCTGAGGTTGCAGACGTTCCTGACCGCGGGGCCCAAAGAGGCGCGGGCGTGGGTGATTCACCAGGGTGATA
CCGCGCCGAAGGCCGCCGGGGTGATTCACAGCGACTTCGAGAAGGGTTTCATCAAAGCCGAAATCGTCTCCTACGACGAC
CTGATCGCCGCGGGGTCGATGGCGGTGGCCAAGGCCGCCGGCAAGGTCCGGATGGAGGGCAAGGACTACGTCATGGCCGA
CGGCGACGTGGTCGAGTTCCGGTTCAACGTGTAG

Upstream 100 bases:

>100_bases
GCTCGTAAATACCTCGTAGCGATCGCGGGCGTGCCACGGCGCGGCGCAGGAATGGTCGCCCGGTCGGTCGCCGGCGCCGG
GCCCCTAGACTTGATTCCCT

Downstream 100 bases:

>100_bases
CTCGGCGCCGCCGCCGAGCGTGGGGGATATGCACGCAGCTGGTGCGATTTTCGTACGTTAGACCCACGCTCGACGATGCG
ATTGAGCAGCCGCTCGGTTG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 356

Protein sequence:

>357_residues
MSLSLGIVGLPNVGKSTLFNALTRNNVVAANYPFATIEPNEGVVPLPDPRLDKLAEMFKSERIVAAPVTFVDIAGLVKGA
SEGAGLGNKFLAHIRECDAICQVVRVFADDDVTHVAGQVDPRSDIEVVETELILADLQTLERAVGRLEKEARTSKERRPV
YEAALAAQETLNGGKTLFSAGTDTSLLRELNLLTTKPFLYVFNADESVLTDPARIAELRELVAPADAVFLDAAIESELIE
LDDESAAELLESIGQTERGLDALARAGFHTLRLQTFLTAGPKEARAWVIHQGDTAPKAAGVIHSDFEKGFIKAEIVSYDD
LIAAGSMAVAKAAGKVRMEGKDYVMADGDVVEFRFNV

Sequences:

>Translated_357_residues
MSLSLGIVGLPNVGKSTLFNALTRNNVVAANYPFATIEPNEGVVPLPDPRLDKLAEMFKSERIVAAPVTFVDIAGLVKGA
SEGAGLGNKFLAHIRECDAICQVVRVFADDDVTHVAGQVDPRSDIEVVETELILADLQTLERAVGRLEKEARTSKERRPV
YEAALAAQETLNGGKTLFSAGTDTSLLRELNLLTTKPFLYVFNADESVLTDPARIAELRELVAPADAVFLDAAIESELIE
LDDESAAELLESIGQTERGLDALARAGFHTLRLQTFLTAGPKEARAWVIHQGDTAPKAAGVIHSDFEKGFIKAEIVSYDD
LIAAGSMAVAKAAGKVRMEGKDYVMADGDVVEFRFNV
>Mature_356_residues
SLSLGIVGLPNVGKSTLFNALTRNNVVAANYPFATIEPNEGVVPLPDPRLDKLAEMFKSERIVAAPVTFVDIAGLVKGAS
EGAGLGNKFLAHIRECDAICQVVRVFADDDVTHVAGQVDPRSDIEVVETELILADLQTLERAVGRLEKEARTSKERRPVY
EAALAAQETLNGGKTLFSAGTDTSLLRELNLLTTKPFLYVFNADESVLTDPARIAELRELVAPADAVFLDAAIESELIEL
DDESAAELLESIGQTERGLDALARAGFHTLRLQTFLTAGPKEARAWVIHQGDTAPKAAGVIHSDFEKGFIKAEIVSYDDL
IAAGSMAVAKAAGKVRMEGKDYVMADGDVVEFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=42.6630434782609, Blast_Score=289, Evalue=3e-78,
Organism=Homo sapiens, GI58761502, Length=171, Percent_Identity=40.9356725146199, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI24308117, Length=127, Percent_Identity=31.496062992126, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=50.4132231404959, Blast_Score=358, Evalue=1e-100,
Organism=Escherichia coli, GI1789574, Length=128, Percent_Identity=34.375, Blast_Score=70, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=40.4371584699454, Blast_Score=271, Evalue=3e-73,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=39.1891891891892, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=37.7308707124011, Blast_Score=216, Evalue=4e-57,
Organism=Saccharomyces cerevisiae, GI6321649, Length=164, Percent_Identity=33.5365853658537, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=43.0517711171662, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=43.0517711171662, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=43.0517711171662, Blast_Score=288, Evalue=5e-78,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=40.9230769230769, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24585318, Length=151, Percent_Identity=29.8013245033113, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20129375, Length=110, Percent_Identity=35.4545454545455, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 38422; Mature: 38291

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSLGIVGLPNVGKSTLFNALTRNNVVAANYPFATIEPNEGVVPLPDPRLDKLAEMFKS
CCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEECCCCCHHHHHHHHHHC
ERIVAAPVTFVDIAGLVKGASEGAGLGNKFLAHIRECDAICQVVRVFADDDVTHVAGQVD
CCEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
PRSDIEVVETELILADLQTLERAVGRLEKEARTSKERRPVYEAALAAQETLNGGKTLFSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEC
GTDTSLLRELNLLTTKPFLYVFNADESVLTDPARIAELRELVAPADAVFLDAAIESELIE
CCCHHHHHHHHHHCCCCEEEEEECCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LDDESAAELLESIGQTERGLDALARAGFHTLRLQTFLTAGPKEARAWVIHQGDTAPKAAG
CCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHC
VIHSDFEKGFIKAEIVSYDDLIAAGSMAVAKAAGKVRMEGKDYVMADGDVVEFRFNV
CHHHHHHCCCEEEEEECHHHHHHHCHHHHHHHCCCEEECCCCEEEECCCEEEEEECC
>Mature Secondary Structure 
SLSLGIVGLPNVGKSTLFNALTRNNVVAANYPFATIEPNEGVVPLPDPRLDKLAEMFKS
CCEEEEEECCCCCHHHHHHHHHCCCEEEECCCEEEECCCCCEECCCCCHHHHHHHHHHC
ERIVAAPVTFVDIAGLVKGASEGAGLGNKFLAHIRECDAICQVVRVFADDDVTHVAGQVD
CCEEECCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCC
PRSDIEVVETELILADLQTLERAVGRLEKEARTSKERRPVYEAALAAQETLNGGKTLFSA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCEEEEC
GTDTSLLRELNLLTTKPFLYVFNADESVLTDPARIAELRELVAPADAVFLDAAIESELIE
CCCHHHHHHHHHHCCCCEEEEEECCCHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LDDESAAELLESIGQTERGLDALARAGFHTLRLQTFLTAGPKEARAWVIHQGDTAPKAAG
CCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHC
VIHSDFEKGFIKAEIVSYDDLIAAGSMAVAKAAGKVRMEGKDYVMADGDVVEFRFNV
CHHHHHHCCCEEEEEECHHHHHHHCHHHHHHHCCCEEECCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]