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The map label for this gene is fbiC

Identifier: 41408709

GI number: 41408709

Start: 2942593

End: 2945196

Strand: Reverse

Name: fbiC

Synonym: MAP2611c

Alternate gene names: 41408709

Gene position: 2945196-2942593 (Counterclockwise)

Preceding gene: 41408710

Following gene: 41408708

Centisome position: 60.98

GC content: 70.35

Gene sequence:

>2604_bases
GTGCTGTTGACTCCGGGCGAGGAGCCTACCGCCCTACCTGATCCTGTGGTTCCGGCCAGGGCCTCATCGCGGGCCACGCC
GAAGGCGACCGCCTCGGCGTTACGACGGGTGTTGCGGCGGGCTCGAGATGGCGTTGCGCTGAACATCGACGAGGCGGCGG
TCGCGATGACCGCGCGCGGGGACGACCTGGCGGACCTGTGCGCCAGCGCGGCCCGGGTCCGCGACGCGGGCCTGCAGTCG
GCCGGCCGGCGCGGCCCGGGCGGCGGGCTGCCGATCACCTACTCGCGCAAGGTTTTCATCCCGGTCACCCACCTGTGCCG
GGACAACTGCCACTACTGCACCTTCGTCACCGTGCCGGGCAAACTGCGCGCCCGAGGCGCGGGCCTGTACCTCGAGCCGG
ACGAGATTCTCGACATCGCCCGCCGCGGCGGTGAACTCGGTTGCAAGGAAGCGCTATTCACCCTCGGCGATCGCCCCGAG
GATCGCTGGCCCGAGGCGCGGGAGTGGCTGGAGGCGCGCGGCTACGATTCGACGCTGTCCTACGTGCGGGCGATGGCGAT
CCGGGTGCTCGAAGAGACCGGGCTGTTGCCGCACCTGAACCCCGGCGTGATGAGCTGGTCGGAGATGGCGCGGCTCAAGC
CGGTGGCGCCGTCCATGGGCATGATGCTCGAGACGACGTCGCGGCGGCTGTTCGAGACGAAAGGCCTTGCGCACTACGGC
AGCCCGGACAAGGACCCGGCGGTGCGCCTGCGCACGCTGACCGACGCGGGCCGGTTGTCGATTCCGTTCACCACCGGTCT
GCTGGTCGGCATCGGCGAGACACCCGCCGAACGCGCCGACACCTTGCACGCGATTCGCAAGTCGCACAAGGAGTTCGGCC
ATGTGCAAGAAGTGATCGTGCAGAACTTCCGGGCCAAGGAACACACCGCCATGGCCGCGGTCCCCGACGCCGGCATCGAG
GATTACCTGGCGACCGTGGCGGTGGCGCGGCTGGTGCTGGGCCCCGGGATGCGGATTCAGGCCCCGCCGAACCTGGTGTC
CCGCGACGAATGCCGGGCGCTGATCGCCGCCGGGGTCGACGACTGGGGTGGTGTGTCACCGCTGACGCCCGACCATGTCA
ACCCCGAGCGGCCGTGGCCGGCGTTGGACGAATTGGCCGCCGTCACTGCCGAATCCGGCTACGAGCTGGTCCAGCGGCTG
ACCGCGCAGCCCAAATACGTGCAGGCGGGTGCGGCCTGGATCGACCCGCGGGTGTCCGGGCATGTCCGGGCGCTGGCCGA
TCCGGTGACCGGTCTGGCCCGCGACGTCAATCCGGTGGGGCTGCCGTGGCAGGAACCCGACGACGTCGGTTCCTCGGGCC
GCGTCGACCTCAACGCGGCGATCGACACGCAGGGCCGCAACAGCGAGACCTGCAGCGACATCGACAGCGCCTTCGGCGAC
TGGGAGTCGATCCGCGCGCACGTGCACGAGCTGGCCGCGCAGGGCGCCAGAGCGCCGGAACGCCTGGACAGCGACGTGCT
CGCCGCGCTGCGCTCCGCCGAACGCGACCCGGCCGGCTGCACCGACAGCGAATACCTGTCGCTGGCCACCGCCGACGGTC
CGGCGCTGGAAGCCGTTGCTGCCCTTGCGGATTCGTTGCGCCGCGACACCGTCGGCGACGACGTGACGTTCGTGGTGAAC
CGCAACATCAACTTCACCAACATCTGCTACACCGGTTGCCGGTTCTGCGCCTTCGCGCAGCGCAAGGGCGACGCCGACGC
GTACTCGCTGTCTACCGAGGAGGTCGCCGACCGCGCCTGGGAGGCGCACGTCGCCGGCGCCACCGAGGTGTGCATGCAGG
GCGGCATCGACCCCGAACTGCCGGTCACCGGCTACGCCGATCTGGTCCGCGCGGTCAAGGCGCGGGTGCCGTCGATGCAC
GTGCACGCGTTCTCGCCGATGGAGATCGCCAACGGGGTGACCAAGAGCGGGCTGTCGATCAGGGAGTGGCTGATCAGCCT
GCGCGAGGCCGGGCTGGACACCATCCCCGGCACCGCGGCCGAGATCCTCGACGACGAGGTGCGCTGGGTGCTGACCAAGG
GCAAGCTGCCGACCTCGCTGTGGATCGAGATCGTCACCACCGCACACGAAGTGGGGCTGCGGTCGAGCTCGACCATGATG
TACGGCCACGTCGACAACCCCCGGCACTGGGTGGGCCACCTCAACGTGCTGCGCGACATCCAGGACCGCACCGGCGGTTT
CACCGAGTTCGTGCCGCTGCCCTTCGTGCATCAGAGCTCGCCGCTGTATCTGGCCGGCGCCGCCCGTCCCGGCCCCACCC
ATCGGGACAACCGGGCGGTGCACGCGCTGGCCCGGATCATGTTGCACGGCCGCATCTCCCAGATCCAGACCAGCTGGGTC
AAGCTCGGAGTGCAGCGCACCCAGGTGATGCTCAACGGCGGCGCCAACGACCTGGGCGGCACGCTGATGGAGGAGACCAT
CTCCCGGATGGCCGGCTCCGAACACGGGTCGGCTAAGACCGTGGCCGAGCTGACCGCGATCGCCGAGGGCATCGGGCGCC
CGGCGCGCCAGCGCACCACCGACTACACCCCGCTGGCCGCCTAG

Upstream 100 bases:

>100_bases
CTACTGTTGACAGTTGCCCATCCGGGACCCGCCACGGGTGCCACGATTTCACATGTTGGGACGCGCGGATGAAATTCGAT
CGTGGGGAAGTTACACCAAG

Downstream 100 bases:

>100_bases
TTCGCTTTCCTGTCACAGCCGGCGGGTATACCCGAGACCGTGAAGCGACGAATTGACGACGATCGATTTCCGGAGTGGCG
TCCGTTCTGCGACGCGGCGC

Product: FO synthase

Products: NA

Alternate protein names: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase

Number of amino acids: Translated: 867; Mature: 867

Protein sequence:

>867_residues
MLLTPGEEPTALPDPVVPARASSRATPKATASALRRVLRRARDGVALNIDEAAVAMTARGDDLADLCASAARVRDAGLQS
AGRRGPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRARGAGLYLEPDEILDIARRGGELGCKEALFTLGDRPE
DRWPEAREWLEARGYDSTLSYVRAMAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETKGLAHYG
SPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETPAERADTLHAIRKSHKEFGHVQEVIVQNFRAKEHTAMAAVPDAGIE
DYLATVAVARLVLGPGMRIQAPPNLVSRDECRALIAAGVDDWGGVSPLTPDHVNPERPWPALDELAAVTAESGYELVQRL
TAQPKYVQAGAAWIDPRVSGHVRALADPVTGLARDVNPVGLPWQEPDDVGSSGRVDLNAAIDTQGRNSETCSDIDSAFGD
WESIRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADGPALEAVAALADSLRRDTVGDDVTFVVN
RNINFTNICYTGCRFCAFAQRKGDADAYSLSTEEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSMH
VHAFSPMEIANGVTKSGLSIREWLISLREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMM
YGHVDNPRHWVGHLNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAVHALARIMLHGRISQIQTSWV
KLGVQRTQVMLNGGANDLGGTLMEETISRMAGSEHGSAKTVAELTAIAEGIGRPARQRTTDYTPLAA

Sequences:

>Translated_867_residues
MLLTPGEEPTALPDPVVPARASSRATPKATASALRRVLRRARDGVALNIDEAAVAMTARGDDLADLCASAARVRDAGLQS
AGRRGPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRARGAGLYLEPDEILDIARRGGELGCKEALFTLGDRPE
DRWPEAREWLEARGYDSTLSYVRAMAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETKGLAHYG
SPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETPAERADTLHAIRKSHKEFGHVQEVIVQNFRAKEHTAMAAVPDAGIE
DYLATVAVARLVLGPGMRIQAPPNLVSRDECRALIAAGVDDWGGVSPLTPDHVNPERPWPALDELAAVTAESGYELVQRL
TAQPKYVQAGAAWIDPRVSGHVRALADPVTGLARDVNPVGLPWQEPDDVGSSGRVDLNAAIDTQGRNSETCSDIDSAFGD
WESIRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADGPALEAVAALADSLRRDTVGDDVTFVVN
RNINFTNICYTGCRFCAFAQRKGDADAYSLSTEEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSMH
VHAFSPMEIANGVTKSGLSIREWLISLREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMM
YGHVDNPRHWVGHLNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAVHALARIMLHGRISQIQTSWV
KLGVQRTQVMLNGGANDLGGTLMEETISRMAGSEHGSAKTVAELTAIAEGIGRPARQRTTDYTPLAA
>Mature_867_residues
MLLTPGEEPTALPDPVVPARASSRATPKATASALRRVLRRARDGVALNIDEAAVAMTARGDDLADLCASAARVRDAGLQS
AGRRGPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPGKLRARGAGLYLEPDEILDIARRGGELGCKEALFTLGDRPE
DRWPEAREWLEARGYDSTLSYVRAMAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETKGLAHYG
SPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETPAERADTLHAIRKSHKEFGHVQEVIVQNFRAKEHTAMAAVPDAGIE
DYLATVAVARLVLGPGMRIQAPPNLVSRDECRALIAAGVDDWGGVSPLTPDHVNPERPWPALDELAAVTAESGYELVQRL
TAQPKYVQAGAAWIDPRVSGHVRALADPVTGLARDVNPVGLPWQEPDDVGSSGRVDLNAAIDTQGRNSETCSDIDSAFGD
WESIRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADGPALEAVAALADSLRRDTVGDDVTFVVN
RNINFTNICYTGCRFCAFAQRKGDADAYSLSTEEVADRAWEAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSMH
VHAFSPMEIANGVTKSGLSIREWLISLREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMM
YGHVDNPRHWVGHLNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAVHALARIMLHGRISQIQTSWV
KLGVQRTQVMLNGGANDLGGTLMEETISRMAGSEHGSAKTVAELTAIAEGIGRPARQRTTDYTPLAA

Specific function: Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO)

COG id: COG1060

COG function: function code HR; Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the radical SAM superfamily. CofH family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FBIC_MYCPA (Q73WP9)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961545.1
- ProteinModelPortal:   Q73WP9
- EnsemblBacteria:   EBMYCT00000036793
- GeneID:   2719780
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2611c
- NMPDR:   fig|262316.1.peg.2611
- GeneTree:   EBGT00050000016725
- HOGENOM:   HBG335564
- OMA:   RAGIDDW
- ProtClustDB:   PRK09234
- HAMAP:   MF_01611
- HAMAP:   MF_01612
- InterPro:   IPR013785
- InterPro:   IPR019940
- InterPro:   IPR006638
- InterPro:   IPR019939
- InterPro:   IPR020050
- InterPro:   IPR007197
- Gene3D:   G3DSA:3.20.20.70
- SMART:   SM00729
- TIGRFAMs:   TIGR00423
- TIGRFAMs:   TIGR03550
- TIGRFAMs:   TIGR03551

Pfam domain/function: PF04055 Radical_SAM

EC number: NA

Molecular weight: Translated: 93484; Mature: 93484

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTPGEEPTALPDPVVPARASSRATPKATASALRRVLRRARDGVALNIDEAAVAMTARG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHEEEEECCC
DDLADLCASAARVRDAGLQSAGRRGPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCEEEEEHHHHHHCCCCEEEEEECCC
KLRARGAGLYLEPDEILDIARRGGELGCKEALFTLGDRPEDRWPEAREWLEARGYDSTLS
CHHHCCCCEEECHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHH
YVRAMAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETKGLAHYG
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
SPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETPAERADTLHAIRKSHKEFGHVQEVIV
CCCCCCCEEEEEECCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QNFRAKEHTAMAAVPDAGIEDYLATVAVARLVLGPGMRIQAPPNLVSRDECRALIAAGVD
HHHCHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCC
DWGGVSPLTPDHVNPERPWPALDELAAVTAESGYELVQRLTAQPKYVQAGAAWIDPRVSG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
HVRALADPVTGLARDVNPVGLPWQEPDDVGSSGRVDLNAAIDTQGRNSETCSDIDSAFGD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCC
WESIRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADGPALEAVA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCCHHHHHHH
ALADSLRRDTVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKGDADAYSLSTEEVADRAW
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHH
EAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSMHVHAFSPMEIANGVTKSGLSI
HHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCCCHH
REWLISLREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEE
YGHVDNPRHWVGHLNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAV
EECCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCEEEEECCCCCCCCCCHHHH
HALARIMLHGRISQIQTSWVKLGVQRTQVMLNGGANDLGGTLMEETISRMAGSEHGSAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHH
VAELTAIAEGIGRPARQRTTDYTPLAA
HHHHHHHHHHHCCCHHHCCCCCCCCCC
>Mature Secondary Structure
MLLTPGEEPTALPDPVVPARASSRATPKATASALRRVLRRARDGVALNIDEAAVAMTARG
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECHHEEEEECCC
DDLADLCASAARVRDAGLQSAGRRGPGGGLPITYSRKVFIPVTHLCRDNCHYCTFVTVPG
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCEEEEEHHHHHHCCCCEEEEEECCC
KLRARGAGLYLEPDEILDIARRGGELGCKEALFTLGDRPEDRWPEAREWLEARGYDSTLS
CHHHCCCCEEECHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHH
YVRAMAIRVLEETGLLPHLNPGVMSWSEMARLKPVAPSMGMMLETTSRRLFETKGLAHYG
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
SPDKDPAVRLRTLTDAGRLSIPFTTGLLVGIGETPAERADTLHAIRKSHKEFGHVQEVIV
CCCCCCCEEEEEECCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QNFRAKEHTAMAAVPDAGIEDYLATVAVARLVLGPGMRIQAPPNLVSRDECRALIAAGVD
HHHCHHHHHHEEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHCCCC
DWGGVSPLTPDHVNPERPWPALDELAAVTAESGYELVQRLTAQPKYVQAGAAWIDPRVSG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCC
HVRALADPVTGLARDVNPVGLPWQEPDDVGSSGRVDLNAAIDTQGRNSETCSDIDSAFGD
CHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHCC
WESIRAHVHELAAQGARAPERLDSDVLAALRSAERDPAGCTDSEYLSLATADGPALEAVA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHEEEECCCCHHHHHHH
ALADSLRRDTVGDDVTFVVNRNINFTNICYTGCRFCAFAQRKGDADAYSLSTEEVADRAW
HHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHH
EAHVAGATEVCMQGGIDPELPVTGYADLVRAVKARVPSMHVHAFSPMEIANGVTKSGLSI
HHHHCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHCCCCCCCCHH
REWLISLREAGLDTIPGTAAEILDDEVRWVLTKGKLPTSLWIEIVTTAHEVGLRSSSTMM
HHHHHHHHHCCCCCCCCCHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEE
YGHVDNPRHWVGHLNVLRDIQDRTGGFTEFVPLPFVHQSSPLYLAGAARPGPTHRDNRAV
EECCCCCHHHHHHHHHHHHHHHHCCCCCEECCCCCEECCCCEEEEECCCCCCCCCCHHHH
HALARIMLHGRISQIQTSWVKLGVQRTQVMLNGGANDLGGTLMEETISRMAGSEHGSAKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHCCCCCCHHH
VAELTAIAEGIGRPARQRTTDYTPLAA
HHHHHHHHHHHCCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA