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The map label for this gene is fadD6

Identifier: 41408669

GI number: 41408669

Start: 2890053

End: 2891831

Strand: Reverse

Name: fadD6

Synonym: MAP2571c

Alternate gene names: 41408669

Gene position: 2891831-2890053 (Counterclockwise)

Preceding gene: 41408670

Following gene: 41408668

Centisome position: 59.87

GC content: 70.38

Gene sequence:

>1779_bases
GTGTCCGATCGTGACGGGGGAGCGCGCACGGCGGTCAAACTGACCGACATCGCAGCTCGGGTGCCGACCGTGCTGGCCGA
CCTGCCGGTGATCGCACGCGGCACGCTGACCGGGCTGCTGGCCCAGCCCGGCTCGCACAAGTCGATCGGCACCGTGTTCC
AGGATCGGGCCGCCCGCTACGGCGACCGGGTCTTCCTGCGGTTCGGCGACCAGCAGCTGACCTACCGGGACGCCAACGCC
GCCGCCAACCGGTACGCCGCGGTGCTGGCCGCCCGCGGTGTCGGCCACGGCGACGTCGTCGCCATCATGCTGCGCAACTC
GCCCAACACGGTGCTGGCCATGCTGGCCGCGGTCAAGTGCGGCGCGGTCGCCGGCATGCTCAACTACCACCAGCGCGGCG
AGGTGCTCGCGCACAGCCTGGGCCTGCTGGACGCCAAGGTGCTCATCGCCGAGACCGATCTGGTCAGCGCGGTGGCCGAG
TGCGGCGGCTCGGGCAGCACCGAGACCCTGACCGCGGAGGACCTGGAGCGCTTCGCGGTCAGCGCGCCGGCCACCAACCC
GGCGTCGGCGTCGGCGGTGCAGGCCCGCGACACCGCGTTCTACATCTTCACCTCGGGCACCACGGGATTCCCCAAGGCCA
GCGTGATGACGCACCTGCGCTGGCTGAAGGCGCTGGCCGCGTTCGGCGGGATCGGGTTGCGGCTGAAGAGCTCCGACACC
CTGTACTGCTGCCTGCCGCTGTACCACAACAATGCGCTGACGGTGGCGTTGTCGTCGGTGATCAACTCGGGGGCGACGCT
GGCGCTGGGCAAGTCGTTCTCGGCGTCGAAGTTCTGGGACGAGGTGATCGCCAACGACGCCACGGCGTTCATCTACATCG
GCGAGGTGTGCCGATACCTGCTCAACCAGCCGGCCAAGCCCACCGACCGGGCGCACCGGGTGCGGCTGATCGCCGGCAAC
GGCCTGCGCCCCGAGATCTGGGACGAGTTCACCCAGCGGTTCGGGATCGCCCGCGTCTGCGAGTTCTACGCCTCCAGCGA
GGGCAACGCCGCGTTCATCAACGTGTTCAACGTGCCCCGGTCCACCGGGATCTTCCCGCTGCCCCTGGCCTACGTCGAGT
ACGACCCCGACACCGGTGCCCCGCTGCGCGGCGACGACGGCCGGGTGCGCCGGGTGCCGCCCGGACAGCCCGGGCTGTTG
CTCAGCCCCGTCAACCGGCTGCAGCCCTTCGACGGCTACACCGACCCCGAATCGAGCGAAAAGAAGTTGGTGCGCAACGC
TTTTCGCGACGGCGACTGCTGGTTCAACACCGGTGACGTGATGAGCCCGCAGGGGCTGGGGCATGCCGCGTTCGTCGACC
GGCTCGGCGACACCTTCCGCTGGAAGGGGGAGAACGTGGCCACCACGCAGGTCGAGGCGGCGCTGGCCTCCGACGGGTCC
GTCGAGGACTGCACGGTCTTCGGGGTCGAGGTGCCGCGCACCGGCGGCCGCGCCGGCATGGCCGCGATCAAACTGCGCGA
CGGCGCCGAGTTCGACGGGCGCTCGCTGGCCCGCACCGTCTACGAGCAGCTGCCCGTCTACGCGCTGCCGCTGTTCGTGC
GGGTGGTGGACTCCATCGAGCAGACCACCACCTTCAAGAGCCGCAAGGTGGAGCTGCGCGAGCAGGGCTACGGCCCCGAG
GTCAAGGACCCGCTGTACGTGCTGGCCGGCCGCGACGAGGGCTACGTGCCGTTCTACGACGAATACCCCGACGAGGTCGC
CGAGGGCAAGCGGCCCTAA

Upstream 100 bases:

>100_bases
CGCGCCGCCGCCGGGCTAGGCTGTCCGCCGAGCTTGCCTTCTTTTTCCTACAAGATCGAGTCCGACCAGGATCGAGTTCC
TACAGAATCGAGGGGATCAG

Downstream 100 bases:

>100_bases
GGCGGCGGTGCGACCTGGCCCTGCGCGCCCTCGGCCGACCAGGCACCATAGACCCGTGCAATCGACGTTCTGCGGGCGTC
CGGTCGCCGGTGATCGCGCG

Product: long-chain-acyl-CoA synthetase

Products: NA

Alternate protein names: Long-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MSDRDGGARTAVKLTDIAARVPTVLADLPVIARGTLTGLLAQPGSHKSIGTVFQDRAARYGDRVFLRFGDQQLTYRDANA
AANRYAAVLAARGVGHGDVVAIMLRNSPNTVLAMLAAVKCGAVAGMLNYHQRGEVLAHSLGLLDAKVLIAETDLVSAVAE
CGGSGSTETLTAEDLERFAVSAPATNPASASAVQARDTAFYIFTSGTTGFPKASVMTHLRWLKALAAFGGIGLRLKSSDT
LYCCLPLYHNNALTVALSSVINSGATLALGKSFSASKFWDEVIANDATAFIYIGEVCRYLLNQPAKPTDRAHRVRLIAGN
GLRPEIWDEFTQRFGIARVCEFYASSEGNAAFINVFNVPRSTGIFPLPLAYVEYDPDTGAPLRGDDGRVRRVPPGQPGLL
LSPVNRLQPFDGYTDPESSEKKLVRNAFRDGDCWFNTGDVMSPQGLGHAAFVDRLGDTFRWKGENVATTQVEAALASDGS
VEDCTVFGVEVPRTGGRAGMAAIKLRDGAEFDGRSLARTVYEQLPVYALPLFVRVVDSIEQTTTFKSRKVELREQGYGPE
VKDPLYVLAGRDEGYVPFYDEYPDEVAEGKRP

Sequences:

>Translated_592_residues
MSDRDGGARTAVKLTDIAARVPTVLADLPVIARGTLTGLLAQPGSHKSIGTVFQDRAARYGDRVFLRFGDQQLTYRDANA
AANRYAAVLAARGVGHGDVVAIMLRNSPNTVLAMLAAVKCGAVAGMLNYHQRGEVLAHSLGLLDAKVLIAETDLVSAVAE
CGGSGSTETLTAEDLERFAVSAPATNPASASAVQARDTAFYIFTSGTTGFPKASVMTHLRWLKALAAFGGIGLRLKSSDT
LYCCLPLYHNNALTVALSSVINSGATLALGKSFSASKFWDEVIANDATAFIYIGEVCRYLLNQPAKPTDRAHRVRLIAGN
GLRPEIWDEFTQRFGIARVCEFYASSEGNAAFINVFNVPRSTGIFPLPLAYVEYDPDTGAPLRGDDGRVRRVPPGQPGLL
LSPVNRLQPFDGYTDPESSEKKLVRNAFRDGDCWFNTGDVMSPQGLGHAAFVDRLGDTFRWKGENVATTQVEAALASDGS
VEDCTVFGVEVPRTGGRAGMAAIKLRDGAEFDGRSLARTVYEQLPVYALPLFVRVVDSIEQTTTFKSRKVELREQGYGPE
VKDPLYVLAGRDEGYVPFYDEYPDEVAEGKRP
>Mature_591_residues
SDRDGGARTAVKLTDIAARVPTVLADLPVIARGTLTGLLAQPGSHKSIGTVFQDRAARYGDRVFLRFGDQQLTYRDANAA
ANRYAAVLAARGVGHGDVVAIMLRNSPNTVLAMLAAVKCGAVAGMLNYHQRGEVLAHSLGLLDAKVLIAETDLVSAVAEC
GGSGSTETLTAEDLERFAVSAPATNPASASAVQARDTAFYIFTSGTTGFPKASVMTHLRWLKALAAFGGIGLRLKSSDTL
YCCLPLYHNNALTVALSSVINSGATLALGKSFSASKFWDEVIANDATAFIYIGEVCRYLLNQPAKPTDRAHRVRLIAGNG
LRPEIWDEFTQRFGIARVCEFYASSEGNAAFINVFNVPRSTGIFPLPLAYVEYDPDTGAPLRGDDGRVRRVPPGQPGLLL
SPVNRLQPFDGYTDPESSEKKLVRNAFRDGDCWFNTGDVMSPQGLGHAAFVDRLGDTFRWKGENVATTQVEAALASDGSV
EDCTVFGVEVPRTGGRAGMAAIKLRDGAEFDGRSLARTVYEQLPVYALPLFVRVVDSIEQTTTFKSRKVELREQGYGPEV
KDPLYVLAGRDEGYVPFYDEYPDEVAEGKRP

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI227499619, Length=568, Percent_Identity=39.0845070422535, Blast_Score=382, Evalue=1e-106,
Organism=Homo sapiens, GI40807357, Length=570, Percent_Identity=37.0175438596491, Blast_Score=360, Evalue=2e-99,
Organism=Homo sapiens, GI38524616, Length=594, Percent_Identity=36.8686868686869, Blast_Score=343, Evalue=4e-94,
Organism=Homo sapiens, GI62865631, Length=560, Percent_Identity=35, Blast_Score=335, Evalue=7e-92,
Organism=Homo sapiens, GI13325055, Length=560, Percent_Identity=35, Blast_Score=335, Evalue=7e-92,
Organism=Homo sapiens, GI13325057, Length=574, Percent_Identity=36.0627177700348, Blast_Score=333, Evalue=3e-91,
Organism=Homo sapiens, GI227499621, Length=550, Percent_Identity=36.3636363636364, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI13236579, Length=510, Percent_Identity=37.2549019607843, Blast_Score=321, Evalue=2e-87,
Organism=Homo sapiens, GI156151445, Length=606, Percent_Identity=22.7722772277228, Blast_Score=86, Evalue=9e-17,
Organism=Escherichia coli, GI221142682, Length=496, Percent_Identity=24.3951612903226, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788107, Length=562, Percent_Identity=23.1316725978648, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786810, Length=521, Percent_Identity=23.2245681381958, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17551278, Length=606, Percent_Identity=33.3333333333333, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI115534440, Length=553, Percent_Identity=34.7197106690778, Blast_Score=330, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6319515, Length=516, Percent_Identity=32.7519379844961, Blast_Score=259, Evalue=9e-70,
Organism=Saccharomyces cerevisiae, GI6319699, Length=527, Percent_Identity=22.7703984819734, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573631, Length=578, Percent_Identity=36.159169550173, Blast_Score=352, Evalue=5e-97,
Organism=Drosophila melanogaster, GI20130353, Length=578, Percent_Identity=36.159169550173, Blast_Score=352, Evalue=6e-97,
Organism=Drosophila melanogaster, GI45552801, Length=568, Percent_Identity=36.7957746478873, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI45550496, Length=568, Percent_Identity=36.7957746478873, Blast_Score=350, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24583465, Length=565, Percent_Identity=36.8141592920354, Blast_Score=347, Evalue=1e-95,
Organism=Drosophila melanogaster, GI24583463, Length=565, Percent_Identity=36.8141592920354, Blast_Score=347, Evalue=1e-95,
Organism=Drosophila melanogaster, GI281364798, Length=565, Percent_Identity=36.8141592920354, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI21355181, Length=474, Percent_Identity=24.0506329113924, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24581924, Length=564, Percent_Identity=23.5815602836879, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24656500, Length=532, Percent_Identity=21.2406015037594, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020459
- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.3 [H]

Molecular weight: Translated: 63796; Mature: 63665

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRDGGARTAVKLTDIAARVPTVLADLPVIARGTLTGLLAQPGSHKSIGTVFQDRAARY
CCCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GDRVFLRFGDQQLTYRDANAAANRYAAVLAARGVGHGDVVAIMLRNSPNTVLAMLAAVKC
CCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHH
GAVAGMLNYHQRGEVLAHSLGLLDAKVLIAETDLVSAVAECGGSGSTETLTAEDLERFAV
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHCCCCCCCEEEHHHHHHHEE
SAPATNPASASAVQARDTAFYIFTSGTTGFPKASVMTHLRWLKALAAFGGIGLRLKSSDT
CCCCCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LYCCLPLYHNNALTVALSSVINSGATLALGKSFSASKFWDEVIANDATAFIYIGEVCRYL
EEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEHHHHHHHH
LNQPAKPTDRAHRVRLIAGNGLRPEIWDEFTQRFGIARVCEFYASSEGNAAFINVFNVPR
HCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
STGIFPLPLAYVEYDPDTGAPLRGDDGRVRRVPPGQPGLLLSPVNRLQPFDGYTDPESSE
CCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEEECCHHHCCCCCCCCCCCCHH
KKLVRNAFRDGDCWFNTGDVMSPQGLGHAAFVDRLGDTFRWKGENVATTQVEAALASDGS
HHHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHHCCCCEEECCCCEEHHHHHHHHHCCCC
VEDCTVFGVEVPRTGGRAGMAAIKLRDGAEFDGRSLARTVYEQLPVYALPLFVRVVDSIE
CCCEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QTTTFKSRKVELREQGYGPEVKDPLYVLAGRDEGYVPFYDEYPDEVAEGKRP
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
SDRDGGARTAVKLTDIAARVPTVLADLPVIARGTLTGLLAQPGSHKSIGTVFQDRAARY
CCCCCCCEEEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GDRVFLRFGDQQLTYRDANAAANRYAAVLAARGVGHGDVVAIMLRNSPNTVLAMLAAVKC
CCEEEEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHH
GAVAGMLNYHQRGEVLAHSLGLLDAKVLIAETDLVSAVAECGGSGSTETLTAEDLERFAV
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHCCCCCCCEEEHHHHHHHEE
SAPATNPASASAVQARDTAFYIFTSGTTGFPKASVMTHLRWLKALAAFGGIGLRLKSSDT
CCCCCCCCCCCCEEECCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LYCCLPLYHNNALTVALSSVINSGATLALGKSFSASKFWDEVIANDATAFIYIGEVCRYL
EEEEEEEEECCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCEEEEEHHHHHHHH
LNQPAKPTDRAHRVRLIAGNGLRPEIWDEFTQRFGIARVCEFYASSEGNAAFINVFNVPR
HCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCC
STGIFPLPLAYVEYDPDTGAPLRGDDGRVRRVPPGQPGLLLSPVNRLQPFDGYTDPESSE
CCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCCCCCEEECCHHHCCCCCCCCCCCCHH
KKLVRNAFRDGDCWFNTGDVMSPQGLGHAAFVDRLGDTFRWKGENVATTQVEAALASDGS
HHHHHHHCCCCCCEECCCCCCCCCCCCHHHHHHHCCCCEEECCCCEEHHHHHHHHHCCCC
VEDCTVFGVEVPRTGGRAGMAAIKLRDGAEFDGRSLARTVYEQLPVYALPLFVRVVDSIE
CCCEEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
QTTTFKSRKVELREQGYGPEVKDPLYVLAGRDEGYVPFYDEYPDEVAEGKRP
HHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]