| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is fabG [H]
Identifier: 41408624
GI number: 41408624
Start: 2838582
End: 2839325
Strand: Reverse
Name: fabG [H]
Synonym: MAP2526c
Alternate gene names: 41408624
Gene position: 2839325-2838582 (Counterclockwise)
Preceding gene: 41408625
Following gene: 41408623
Centisome position: 58.79
GC content: 67.34
Gene sequence:
>744_bases GTGAGTCGCGTGGCGGTAGTAACCGGCGGTGGGTCGGGAATCGGGCGGGCCATCGTCGAACGACTGGCCCACGACCGCCA TCGCGTCGCCGTGTTGGACGTAAACGAAGAAGCCGCCGAAAAGGTGGCGGCGCGGGTGGCGGCCGACGGCGCCCACGCAA TCGCGGTACCGACCGACGTCGCCGAAAGCGCCAGCGTCGCAGCGGCGTTCGAGTCGGTGCGGCGCGCGCTCGGCCCCGTT CAGGTCTTGGTTACCAGCGCGGCGATCACTGGCTTCAAGCCGTTCGGCGAGATCACGATCGAGGACTGGAACCGCCACCT CGCGGTGAACCTCACCGGCACGTTTCTGTGCCTGCAGGCTGCGCTGCCGGACATGGTCGAGGCTGGTTGGGGGCGTGTGG TCACGATTTCTTCGACGGCGGCACAGACGGGATCGCCCCGACAAGGCCACTACTCCGCATCCAAGGGCGGTGTGATCGCG CTGACGAGAACGATCGCGCTCGAATACGCGGTCCACGGGATAACCGCCAACACGGTGCCGCCGTTTTCCGTTGACACCCC GATGCTTCGCGCCGCGCAGGAGGCGGGAAACCTTCCCCCCGTCAAGTACCTTGCCAAGGCATCCCCGGTCGGCAGGCTCG GCACCGGCGAGGACATCGCCGCTGCGTGCGCTTTCCTGTGCTCCGACGAGGCGGGCTACATCACGGGTCAGATCATCGGC GTCAACGGCGGCGCAGTGATCTGA
Upstream 100 bases:
>100_bases CGTTGCGGCGGGTGCTTCACGGGAGGCCTTGTGACCGCGCTGTACGTCCGTATAGACTGGACGATCGTATAGCAGGTGCA GGGGGTGGAAGGCGAGCATT
Downstream 100 bases:
>100_bases ACCAGCGGCACATGCGGATTGAAGCAAGCAACGATCACGGAGGTGTTCAGTGAAGGCACGCGTTGACGCTGCCCGATGCC AGGGGCACACCCTGTGCGCG
Product: hypothetical protein
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 247; Mature: 246
Protein sequence:
>247_residues MSRVAVVTGGGSGIGRAIVERLAHDRHRVAVLDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGPV QVLVTSAAITGFKPFGEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIA LTRTIALEYAVHGITANTVPPFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEAGYITGQIIG VNGGAVI
Sequences:
>Translated_247_residues MSRVAVVTGGGSGIGRAIVERLAHDRHRVAVLDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGPV QVLVTSAAITGFKPFGEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIA LTRTIALEYAVHGITANTVPPFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEAGYITGQIIG VNGGAVI >Mature_246_residues SRVAVVTGGGSGIGRAIVERLAHDRHRVAVLDVNEEAAEKVAARVAADGAHAIAVPTDVAESASVAAAFESVRRALGPVQ VLVTSAAITGFKPFGEITIEDWNRHLAVNLTGTFLCLQAALPDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIAL TRTIALEYAVHGITANTVPPFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEAGYITGQIIGV NGGAVI
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=38.3399209486166, Blast_Score=141, Evalue=5e-34, Organism=Homo sapiens, GI40254992, Length=244, Percent_Identity=34.8360655737705, Blast_Score=129, Evalue=2e-30, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=31.7269076305221, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI5031737, Length=250, Percent_Identity=34, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI19923817, Length=249, Percent_Identity=29.3172690763052, Blast_Score=95, Evalue=4e-20, Organism=Homo sapiens, GI66933014, Length=147, Percent_Identity=34.6938775510204, Blast_Score=95, Evalue=7e-20, Organism=Homo sapiens, GI7705925, Length=246, Percent_Identity=30.4878048780488, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=30.8300395256917, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=29.718875502008, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI126723750, Length=249, Percent_Identity=26.9076305220884, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI4504505, Length=188, Percent_Identity=31.9148936170213, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=30.939226519337, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI25282469, Length=232, Percent_Identity=28.0172413793103, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=34.7150259067358, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=29.6442687747036, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI40807363, Length=192, Percent_Identity=27.0833333333333, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI226371731, Length=193, Percent_Identity=33.160621761658, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=227, Percent_Identity=28.1938325991189, Blast_Score=74, Evalue=9e-14, Organism=Homo sapiens, GI31542939, Length=206, Percent_Identity=29.6116504854369, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI210032110, Length=186, Percent_Identity=25.8064516129032, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI142976729, Length=191, Percent_Identity=23.5602094240838, Blast_Score=70, Evalue=1e-12, Organism=Homo sapiens, GI4503301, Length=219, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI224922801, Length=172, Percent_Identity=30.8139534883721, Blast_Score=65, Evalue=8e-11, Organism=Homo sapiens, GI223718074, Length=182, Percent_Identity=34.6153846153846, Blast_Score=64, Evalue=9e-11, Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=37.1428571428571, Blast_Score=148, Evalue=4e-37, Organism=Escherichia coli, GI1790717, Length=242, Percent_Identity=32.2314049586777, Blast_Score=133, Evalue=8e-33, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=32, Blast_Score=128, Evalue=4e-31, Organism=Escherichia coli, GI2367175, Length=251, Percent_Identity=35.4581673306773, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1788459, Length=250, Percent_Identity=33.2, Blast_Score=122, Evalue=3e-29, Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=32.9457364341085, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1787905, Length=245, Percent_Identity=31.4285714285714, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=27.9352226720648, Blast_Score=94, Evalue=7e-21, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=27.8225806451613, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1786812, Length=197, Percent_Identity=32.48730964467, Blast_Score=84, Evalue=6e-18, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=24.4, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI2367365, Length=243, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=35.3658536585366, Blast_Score=124, Evalue=3e-29, Organism=Caenorhabditis elegans, GI25147288, Length=246, Percent_Identity=35.3658536585366, Blast_Score=123, Evalue=9e-29, Organism=Caenorhabditis elegans, GI17567345, Length=190, Percent_Identity=30, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=30.3664921465969, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=28.1632653061224, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI17538182, Length=254, Percent_Identity=31.496062992126, Blast_Score=91, Evalue=4e-19, Organism=Caenorhabditis elegans, GI71994604, Length=246, Percent_Identity=29.2682926829268, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=26.1044176706827, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=29.0836653386454, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17536651, Length=249, Percent_Identity=27.3092369477912, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI193203117, Length=189, Percent_Identity=28.042328042328, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI193203115, Length=189, Percent_Identity=28.042328042328, Blast_Score=81, Evalue=4e-16, Organism=Caenorhabditis elegans, GI17536025, Length=253, Percent_Identity=28.0632411067194, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17508895, Length=235, Percent_Identity=23.4042553191489, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17568967, Length=191, Percent_Identity=30.3664921465969, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17561272, Length=236, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI17562910, Length=262, Percent_Identity=26.7175572519084, Blast_Score=77, Evalue=5e-15, Organism=Caenorhabditis elegans, GI193204405, Length=261, Percent_Identity=26.4367816091954, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=26.9961977186312, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI115534694, Length=242, Percent_Identity=30.1652892561983, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17508651, Length=249, Percent_Identity=29.718875502008, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17531453, Length=261, Percent_Identity=26.0536398467433, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17560332, Length=261, Percent_Identity=28.735632183908, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17551412, Length=257, Percent_Identity=28.0155642023346, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=27.2373540856031, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17538486, Length=261, Percent_Identity=27.2030651340996, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=27.7992277992278, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534660, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17544670, Length=262, Percent_Identity=23.6641221374046, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6324126, Length=247, Percent_Identity=29.5546558704453, Blast_Score=91, Evalue=2e-19, Organism=Saccharomyces cerevisiae, GI6322861, Length=207, Percent_Identity=29.4685990338164, Blast_Score=82, Evalue=1e-16, Organism=Drosophila melanogaster, GI24639444, Length=244, Percent_Identity=34.0163934426229, Blast_Score=127, Evalue=6e-30, Organism=Drosophila melanogaster, GI21355319, Length=246, Percent_Identity=30.8943089430894, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI18859837, Length=245, Percent_Identity=31.0204081632653, Blast_Score=97, Evalue=1e-20, Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=31.1740890688259, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=2e-19, Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=31.496062992126, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI24643142, Length=245, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=30.6122448979592, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI28571526, Length=246, Percent_Identity=29.2682926829268, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=29.4736842105263, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24640492, Length=192, Percent_Identity=25.5208333333333, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24649181, Length=221, Percent_Identity=31.2217194570136, Blast_Score=77, Evalue=8e-15, Organism=Drosophila melanogaster, GI221331216, Length=201, Percent_Identity=31.8407960199005, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI221331218, Length=200, Percent_Identity=31.5, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665243, Length=200, Percent_Identity=31.5, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI21355631, Length=214, Percent_Identity=28.0373831775701, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24581726, Length=191, Percent_Identity=25.6544502617801, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24665247, Length=201, Percent_Identity=31.8407960199005, Blast_Score=71, Evalue=6e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25277; Mature: 25146
Theoretical pI: Translated: 6.51; Mature: 6.51
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 2.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSRVAVVTGGGSGIGRAIVERLAHDRHRVAVLDVNEEAAEKVAARVAADGAHAIAVPTDV CCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCH AESASVAAAFESVRRALGPVQVLVTSAAITGFKPFGEITIEDWNRHLAVNLTGTFLCLQA HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEHHHHHHHHH ALPDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAVHGITANTVP HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEECCCCC PFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEAGYITGQIIG CCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE VNGGAVI CCCCCCC >Mature Secondary Structure SRVAVVTGGGSGIGRAIVERLAHDRHRVAVLDVNEEAAEKVAARVAADGAHAIAVPTDV CEEEEEECCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCH AESASVAAAFESVRRALGPVQVLVTSAAITGFKPFGEITIEDWNRHLAVNLTGTFLCLQA HHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEEHHHHHHHHH ALPDMVEAGWGRVVTISSTAAQTGSPRQGHYSASKGGVIALTRTIALEYAVHGITANTVP HHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCEECCCCC PFSVDTPMLRAAQEAGNLPPVKYLAKASPVGRLGTGEDIAAACAFLCSDEAGYITGQIIG CCCCCCHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEEEE VNGGAVI CCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9537320 [H]