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The map label for this gene is mer [H]

Identifier: 41408622

GI number: 41408622

Start: 2835965

End: 2836894

Strand: Reverse

Name: mer [H]

Synonym: MAP2524c

Alternate gene names: 41408622

Gene position: 2836894-2835965 (Counterclockwise)

Preceding gene: 41408623

Following gene: 41408621

Centisome position: 58.74

GC content: 67.53

Gene sequence:

>930_bases
ATGCGGATCGGGCTGACCGGCGGCGCGTCATCGACCGACAAGATCGTGGAGCAGGCCCAAGCGGCTGAAGCCGAGGGCTT
CACGTCCCTGTGGTACGCCAGCACGGTGGCCGGCGACCCGCTGGTGGCGATGGCCCTGGCGGGACGGGCCACCACATCCA
TCGAACTGGGCACCGCCGTCCTTCAGACGTATCCCTGTCACCCGCTGCTGCAGGCTAACCGGGTAGCCGCCACGGCAAAT
GCCATGGGCCGCCCGGGATTCACGCTCGGGCTGGGCCCCTCGCACGAGCCGCTCGTCAGCGGCGTGCTCGGCTTGTCCTA
CGACCATCCCGGCAGGAACACCGAAGAATATCTGCGCATCATCAGTGCCCTGTTGCGGGGCGAGGAAGTCGACTACTCCG
GTCAGGACTGGACGACCCGCAGTCCCGCCGGGGTGGTCAGACTCGACTATGAGGTGCCGCTGCTGCTGTCGGCGCTGTCA
CCCCGGATGTTGCGCATTGCAGGTCGTTTCGCCGATGGAGTCGTGCTCTGGATGGCGTCGGCATCGGTCATCGAATCCCG
CATCGCACCCGCGCTCCGCCACGCGACCACGGAATGGGGTCGGCCACCGCCAAGGATCGTCGCCGGACTACCCGTCGCCG
TGCACGACGACCCGGTCGAGGCCCGGGCGGCCACCGCGGCGATGTCGACGATGTACGCGGGGATGACCAACTATCAGCGG
GTCATCGAGGCGGGCGGCGGCGCCACCCCTGCCGATGTCGCGATCATCGGCAACGAGGAGTCGGTGCGAAAACAACTGCA
GGACCTGCTCGATGCCGGAGCCACCGACATCTGGGCACAGCCCATCGGAGTCGGTGATGAGCGAGCACAACGAACGGCAT
CGGCCCAACGCACTCGGGAACTGCTCAGCGAACTCGCCCGCCTGGGTTAG

Upstream 100 bases:

>100_bases
CGACCTATCACCGAGTACAAGGAGCAAGCCCGTCTCCCTGGATGACGACCACGACCACTGGCGCATATCCGTTGACGTGC
AGAAAGATTGGAGAGCGGCG

Downstream 100 bases:

>100_bases
GACTTCTGACCACTACGCGACTATGCGTGATGAGCTGCGATAGCCGAGGGCGTCGCCGGCCTGATCGCCTCCAAGACGCG
ACCCGTCCCTCCGGCGAAGT

Product: hypothetical protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRIGLTGGASSTDKIVEQAQAAEAEGFTSLWYASTVAGDPLVAMALAGRATTSIELGTAVLQTYPCHPLLQANRVAATAN
AMGRPGFTLGLGPSHEPLVSGVLGLSYDHPGRNTEEYLRIISALLRGEEVDYSGQDWTTRSPAGVVRLDYEVPLLLSALS
PRMLRIAGRFADGVVLWMASASVIESRIAPALRHATTEWGRPPPRIVAGLPVAVHDDPVEARAATAAMSTMYAGMTNYQR
VIEAGGGATPADVAIIGNEESVRKQLQDLLDAGATDIWAQPIGVGDERAQRTASAQRTRELLSELARLG

Sequences:

>Translated_309_residues
MRIGLTGGASSTDKIVEQAQAAEAEGFTSLWYASTVAGDPLVAMALAGRATTSIELGTAVLQTYPCHPLLQANRVAATAN
AMGRPGFTLGLGPSHEPLVSGVLGLSYDHPGRNTEEYLRIISALLRGEEVDYSGQDWTTRSPAGVVRLDYEVPLLLSALS
PRMLRIAGRFADGVVLWMASASVIESRIAPALRHATTEWGRPPPRIVAGLPVAVHDDPVEARAATAAMSTMYAGMTNYQR
VIEAGGGATPADVAIIGNEESVRKQLQDLLDAGATDIWAQPIGVGDERAQRTASAQRTRELLSELARLG
>Mature_309_residues
MRIGLTGGASSTDKIVEQAQAAEAEGFTSLWYASTVAGDPLVAMALAGRATTSIELGTAVLQTYPCHPLLQANRVAATAN
AMGRPGFTLGLGPSHEPLVSGVLGLSYDHPGRNTEEYLRIISALLRGEEVDYSGQDWTTRSPAGVVRLDYEVPLLLSALS
PRMLRIAGRFADGVVLWMASASVIESRIAPALRHATTEWGRPPPRIVAGLPVAVHDDPVEARAATAAMSTMYAGMTNYQR
VIEAGGGATPADVAIIGNEESVRKQLQDLLDAGATDIWAQPIGVGDERAQRTASAQRTRELLSELARLG

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 32665; Mature: 32665

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGLTGGASSTDKIVEQAQAAEAEGFTSLWYASTVAGDPLVAMALAGRATTSIELGTAV
CEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHH
LQTYPCHPLLQANRVAATANAMGRPGFTLGLGPSHEPLVSGVLGLSYDHPGRNTEEYLRI
HHHCCCCHHHHCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHH
ISALLRGEEVDYSGQDWTTRSPAGVVRLDYEVPLLLSALSPRMLRIAGRFADGVVLWMAS
HHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCHHHHHHHHHHHCCHHHHHHH
ASVIESRIAPALRHATTEWGRPPPRIVAGLPVAVHDDPVEARAATAAMSTMYAGMTNYQR
HHHHHHHHHHHHHHHHHHCCCCCCHHEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VIEAGGGATPADVAIIGNEESVRKQLQDLLDAGATDIWAQPIGVGDERAQRTASAQRTRE
HHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHH
LLSELARLG
HHHHHHHCC
>Mature Secondary Structure
MRIGLTGGASSTDKIVEQAQAAEAEGFTSLWYASTVAGDPLVAMALAGRATTSIELGTAV
CEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHH
LQTYPCHPLLQANRVAATANAMGRPGFTLGLGPSHEPLVSGVLGLSYDHPGRNTEEYLRI
HHHCCCCHHHHCCHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHHHH
ISALLRGEEVDYSGQDWTTRSPAGVVRLDYEVPLLLSALSPRMLRIAGRFADGVVLWMAS
HHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCHHHHHHHHHHHCCHHHHHHH
ASVIESRIAPALRHATTEWGRPPPRIVAGLPVAVHDDPVEARAATAAMSTMYAGMTNYQR
HHHHHHHHHHHHHHHHHHCCCCCCHHEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHH
VIEAGGGATPADVAIIGNEESVRKQLQDLLDAGATDIWAQPIGVGDERAQRTASAQRTRE
HHHCCCCCCCCCEEEECCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHH
LLSELARLG
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]