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The map label for this gene is rho

Identifier: 41408562

GI number: 41408562

Start: 2768110

End: 2769972

Strand: Reverse

Name: rho

Synonym: MAP2464c

Alternate gene names: 41408562

Gene position: 2769972-2768110 (Counterclockwise)

Preceding gene: 41408563

Following gene: 41408561

Centisome position: 57.35

GC content: 69.24

Gene sequence:

>1863_bases
GTGACTGATACGGACCTGTTCACGGCTGGCGAAAACACTGACGCCAATCAACTCTCTACTGCCGTGACCACAGACACCCC
AGACGCGAAGACGCATGCGCCGGTCGGTGCCCTGACCACCATGGTGCTGCCCGAGCTGCGCGCGCTGGCTAACCAGGTCG
GCGTCAAGGGGACGTCGGGCATGCGTAAGAACGAACTGATCGCCGCGATCAAGGAAGTCCGGGGGCAGGCCAACGGCGCC
GCGCCCGCTGAGCAGGCCAACGGCGCCGAGCCGGCCGAGGACAGCGGCAAGCCCGACGCCAAGGACGCCAAGGACGACAC
CACGCCCGACACCAAGGACGCCAACGACCACACCGGCGCTCAAAGCGCCGCCGAGGCGCCGGCCCCGAGCGAGCAGAACG
GCGCCACCGCCGAGGCGCCGCGCCGCGAGCGACGCAGCGCGTCCCGCGACGCGGGAGCGGCCGGCCGGGGCAGCGACGAC
GCCGACCGCGAGACCGACGGCCGCGAGCAAAGCAAGCAGGACAGCCGCGAGCAAAGCAAGCAGGACGGCGGCGACCAGGA
CCAGCAGAGCTCCGGTGGCCAGCAGGGGCGCGGCTCCAACCAGCAGGACGACGACGGCGAGGGACGTCAGGGCCGGCGGG
GACGCCGCTTCCGTGACCGCCGGCGCCGCGGCGAACGGTCCGGCGAGGGCGGCGACGCCGAACTGCGCGAGGACGACGTC
GTCCAGCCGGTGGCCGGCATTCTCGACGTGCTCGACAACTACGCCTTCGTGCGCACCTCCGGCTACCTGGCCGGCCCGCA
CGACGTCTACGTGTCGATGAACATGGTGCGCAAGAACGGCCTTCGCCGCGGTGACGCGGTGACCGGTGCGGTCCGGGTGC
CCAAGGACGGCGAGCAGCCCAACCAGCGGCAGAAGTTCAACCCGTTGGTGCGCCTGGACAGTGTCAACGGCGGCTCCGTC
GAGGACGCCAAGAAGCGTCCCGAATTCGGCAAGCTGACGCCGCTGTACCCCAACCAGCGGCTGCGCCTGGAGACCACGCC
GGACCGGCTGACCACCCGGGTCATCGACCTGATCATGCCGATCGGCAAGGGCCAGCGCGCGCTGATCGTGTCGCCGCCCA
AGGCGGGTAAGACGACCATCCTGCAGGACATCGCCAACGCGATCACCAAGAACAACCCGGAATGCCACCTCATGGTCGTG
CTCGTCGACGAGCGGCCCGAGGAGGTCACCGACATGCAGCGCTCGGTCAAGGGCGAGGTCATCGCCTCGACGTTCGACCG
GCCGCCGTCCGACCACACCTCGGTCGCCGAGCTGGCCATCGAGCGCGCCAAGCGCCTCGTCGAGCAGGGCAAGGACGTCG
TCGTGCTGCTGGACTCGATCACCCGGCTGGGCCGCGCCTACAACAACGCGTCGCCCGCCTCGGGCCGCATCCTGTCCGGT
GGTGTGGACTCCACCGCGCTCTACCCGCCCAAGCGGTTCCTGGGCGCCGCCCGCAACATCGAGGAAGGCGGCTCGCTGAC
CATCATCGCCACCGCCATGGTCGAGACCGGATCCACCGGTGACACCGTCATCTTCGAGGAGTTCAAGGGCACCGGTAACG
CCGAGCTCAAGCTGGACCGCAAGATCGCCGAGCGGCGGGTCTTCCCGGCGGTCGACGTTAACCCCTCGGGTACCCGCAAG
GACGAGCTGCTGCTGTCGCCGGACGAGTTCGGCATCGTGCACAAGCTGCGCCGGGTGCTGTCCGGCCTGGATTCGCACCA
GGCCATCGACCTGCTGATGAGCCAGCTGCGCAAGACCAAGAACAACTACGAGTTCCTGGTCCAGGTGTCCAAGACCACGC
CCGGGGCGATGGACAACGACTAG

Upstream 100 bases:

>100_bases
GATCACCGTTGCAAAGTCGATGATTGGGCGCACTCGGCAATTTGGCTGAATGCAACGAACCCCCTGTATGAGCTGATCAG
CGGGGGAAGAAAGGAAATCC

Downstream 100 bases:

>100_bases
CCGCGCGACGCCCGGCGGGAATGCCCCGACGCATCCCACTGTTTTGGGCGGGTAGCGGTTGACCTGGCATAATCGACGCG
CGACGAGATCGAAGAGGAAT

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 620; Mature: 619

Protein sequence:

>620_residues
MTDTDLFTAGENTDANQLSTAVTTDTPDAKTHAPVGALTTMVLPELRALANQVGVKGTSGMRKNELIAAIKEVRGQANGA
APAEQANGAEPAEDSGKPDAKDAKDDTTPDTKDANDHTGAQSAAEAPAPSEQNGATAEAPRRERRSASRDAGAAGRGSDD
ADRETDGREQSKQDSREQSKQDGGDQDQQSSGGQQGRGSNQQDDDGEGRQGRRGRRFRDRRRRGERSGEGGDAELREDDV
VQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMNMVRKNGLRRGDAVTGAVRVPKDGEQPNQRQKFNPLVRLDSVNGGSV
EDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITKNNPECHLMVV
LVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSG
GVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRK
DELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGAMDND

Sequences:

>Translated_620_residues
MTDTDLFTAGENTDANQLSTAVTTDTPDAKTHAPVGALTTMVLPELRALANQVGVKGTSGMRKNELIAAIKEVRGQANGA
APAEQANGAEPAEDSGKPDAKDAKDDTTPDTKDANDHTGAQSAAEAPAPSEQNGATAEAPRRERRSASRDAGAAGRGSDD
ADRETDGREQSKQDSREQSKQDGGDQDQQSSGGQQGRGSNQQDDDGEGRQGRRGRRFRDRRRRGERSGEGGDAELREDDV
VQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMNMVRKNGLRRGDAVTGAVRVPKDGEQPNQRQKFNPLVRLDSVNGGSV
EDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITKNNPECHLMVV
LVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSG
GVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRK
DELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGAMDND
>Mature_619_residues
TDTDLFTAGENTDANQLSTAVTTDTPDAKTHAPVGALTTMVLPELRALANQVGVKGTSGMRKNELIAAIKEVRGQANGAA
PAEQANGAEPAEDSGKPDAKDAKDDTTPDTKDANDHTGAQSAAEAPAPSEQNGATAEAPRRERRSASRDAGAAGRGSDDA
DRETDGREQSKQDSREQSKQDGGDQDQQSSGGQQGRGSNQQDDDGEGRQGRRGRRFRDRRRRGERSGEGGDAELREDDVV
QPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMNMVRKNGLRRGDAVTGAVRVPKDGEQPNQRQKFNPLVRLDSVNGGSVE
DAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITKNNPECHLMVVL
VDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGG
VDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKD
ELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGAMDND

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=409, Percent_Identity=52.078239608802, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 66881; Mature: 66750

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDTDLFTAGENTDANQLSTAVTTDTPDAKTHAPVGALTTMVLPELRALANQVGVKGTSG
CCCCCEEECCCCCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MRKNELIAAIKEVRGQANGAAPAEQANGAEPAEDSGKPDAKDAKDDTTPDTKDANDHTGA
CCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QSAAEAPAPSEQNGATAEAPRRERRSASRDAGAAGRGSDDADRETDGREQSKQDSREQSK
HHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
QDGGDQDQQSSGGQQGRGSNQQDDDGEGRQGRRGRRFRDRRRRGERSGEGGDAELREDDV
HCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHH
VQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMNMVRKNGLRRGDAVTGAVRVPKDGEQP
HHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEHHHHHHCCCCCCCCCCCEEECCCCCCCC
NQRQKFNPLVRLDSVNGGSVEDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMP
CHHHHCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHC
IGKGQRALIVSPPKAGKTTILQDIANAITKNNPECHLMVVLVDERPEEVTDMQRSVKGEV
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHH
IASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEEC
GVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDR
CCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCEEEEHH
KIAERRVFPAVDVNPSGTRKDELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTK
HHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NNYEFLVQVSKTTPGAMDND
CCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
TDTDLFTAGENTDANQLSTAVTTDTPDAKTHAPVGALTTMVLPELRALANQVGVKGTSG
CCCCEEECCCCCCHHHHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
MRKNELIAAIKEVRGQANGAAPAEQANGAEPAEDSGKPDAKDAKDDTTPDTKDANDHTGA
CCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
QSAAEAPAPSEQNGATAEAPRRERRSASRDAGAAGRGSDDADRETDGREQSKQDSREQSK
HHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
QDGGDQDQQSSGGQQGRGSNQQDDDGEGRQGRRGRRFRDRRRRGERSGEGGDAELREDDV
HCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHH
VQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMNMVRKNGLRRGDAVTGAVRVPKDGEQP
HHHHHHHHHHHHCCEEEEECCCCCCCCEEEEEHHHHHHCCCCCCCCCCCEEECCCCCCCC
NQRQKFNPLVRLDSVNGGSVEDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMP
CHHHHCCCCEEEECCCCCCCHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHC
IGKGQRALIVSPPKAGKTTILQDIANAITKNNPECHLMVVLVDERPEEVTDMQRSVKGEV
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCHH
IASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSG
HHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCCCCCCCEEEC
GVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDR
CCCCCCCCCCHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCEEEEECCCCCCCCEEEEHH
KIAERRVFPAVDVNPSGTRKDELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTK
HHHHHHCCCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
NNYEFLVQVSKTTPGAMDND
CCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]