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The map label for this gene is kshA [H]

Identifier: 41408441

GI number: 41408441

Start: 2633449

End: 2634603

Strand: Reverse

Name: kshA [H]

Synonym: MAP2343c

Alternate gene names: 41408441

Gene position: 2634603-2633449 (Counterclockwise)

Preceding gene: 41408443

Following gene: 41408440

Centisome position: 54.55

GC content: 67.19

Gene sequence:

>1155_bases
TTGGTCCGGACGGGATACGGAGTGCAAGTGGCGCGTACAGTTTCGGATTCGGCCCCCGATTCGGCCGAGGATCCTTCGGA
GCGGGAGTTCGGGCAGGCCGGCATCGCATTGTCGACCTACCGGTTCCCGACGGGCTGGTTCATCGTGGCGTTCGGATCCG
ACCTGGCCCCCGGCCAGGTCAAGCGCGCGCACTACTTCGGCGAGGAGTTGGTGCTGTTCCGCACCGCGTCGGGGCGGGTG
CACGTGATGGACGCCTACTGTCAGCATTTGGGCGCCAACCTCGGCGTCGGCGGCACCGTGGAGGGCGAGAACATCGTCTG
CCCCTGGCACGGGTGGCAGTGGCGCGGCGACGGCAGCAACGCGCTGATTCCCTACAGCAAGATCGGCTGCAAGAACAACG
TCCGCATCCGCACCTACCCGAGCATGGAGTGGTACGGCTTCGTGCTGGCCTGGCACGAGCGGCACGGCCGGGCCCCGTAC
TGGCAGCCGCCGGTGCTGCCGGAGCTGGAAACCGGCGAGTACTACCCGCTGCATCCGCACACCCAGATGGTCAACCGGGT
CAAGGTGCACCCGCAGATGATCATCGAGAACGCCGCCGACCCCTACCACGTCCAGTACGTGCACAAGGCGGCCAATCCGG
CCACCACCGCGTCGTTCGAGGTGGCCGGCTACCACCTGCACGCGACGGTCAACGCGCATTTCGGCGGGGGCCGGGCGCAG
ACCTGGCTGACCCCGAACGGGCCGGTCGACGCCAAGATCATCTACGACAACTACTCGCTGGGCCTGGGCGTGGTGCGCTT
CCCCAGCGAGCTGGTGGCCACCGTCCAGGTCACCGGTCAGACGCCGGTCGACGAGGACTACACCGACTACTTCTACACCC
AGGCGTCCGTGCGTGAACCGGGCGACACCGGTGACGTGCCCACCGGACGTGCCGCCCGGTTCCTGGCGCTTCAGAAGGAA
GTCATCAAGCAGGACTTCTTCACGTGGGAGAACATGAAGTACCTGGAGAAGCCGAATCTGGCGCCGGAAGAGGCGCATGA
CTATGCGGCGCTTCGCCGTTGGGCGCACCGGTTCTACCCGGGACCCCAACCCGCCCCGACCGATTTCGGTTACACCGCCG
ACGGCGAGCCCGACCCGGCAGCCGCGAAGGCCTGA

Upstream 100 bases:

>100_bases
CGCACGCGGCGGTGGCCGCGTTGACGTTCAATGCTTAAAATAGTAAAAATAGACCTTGTCGTCGAACCGCGGTGAGCGCC
GGGCGGCGCCCGGCTCGCCT

Downstream 100 bases:

>100_bases
TGCGGGCACCGGCCGACTTCGGCGTGGACCGTTTCACCGTGCCCGCCGTGCTGGATCGGCGCGCCGCGCAGCATCCGGAC
CGAGTGATGATGTCGATCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MVRTGYGVQVARTVSDSAPDSAEDPSEREFGQAGIALSTYRFPTGWFIVAFGSDLAPGQVKRAHYFGEELVLFRTASGRV
HVMDAYCQHLGANLGVGGTVEGENIVCPWHGWQWRGDGSNALIPYSKIGCKNNVRIRTYPSMEWYGFVLAWHERHGRAPY
WQPPVLPELETGEYYPLHPHTQMVNRVKVHPQMIIENAADPYHVQYVHKAANPATTASFEVAGYHLHATVNAHFGGGRAQ
TWLTPNGPVDAKIIYDNYSLGLGVVRFPSELVATVQVTGQTPVDEDYTDYFYTQASVREPGDTGDVPTGRAARFLALQKE
VIKQDFFTWENMKYLEKPNLAPEEAHDYAALRRWAHRFYPGPQPAPTDFGYTADGEPDPAAAKA

Sequences:

>Translated_384_residues
MVRTGYGVQVARTVSDSAPDSAEDPSEREFGQAGIALSTYRFPTGWFIVAFGSDLAPGQVKRAHYFGEELVLFRTASGRV
HVMDAYCQHLGANLGVGGTVEGENIVCPWHGWQWRGDGSNALIPYSKIGCKNNVRIRTYPSMEWYGFVLAWHERHGRAPY
WQPPVLPELETGEYYPLHPHTQMVNRVKVHPQMIIENAADPYHVQYVHKAANPATTASFEVAGYHLHATVNAHFGGGRAQ
TWLTPNGPVDAKIIYDNYSLGLGVVRFPSELVATVQVTGQTPVDEDYTDYFYTQASVREPGDTGDVPTGRAARFLALQKE
VIKQDFFTWENMKYLEKPNLAPEEAHDYAALRRWAHRFYPGPQPAPTDFGYTADGEPDPAAAKA
>Mature_384_residues
MVRTGYGVQVARTVSDSAPDSAEDPSEREFGQAGIALSTYRFPTGWFIVAFGSDLAPGQVKRAHYFGEELVLFRTASGRV
HVMDAYCQHLGANLGVGGTVEGENIVCPWHGWQWRGDGSNALIPYSKIGCKNNVRIRTYPSMEWYGFVLAWHERHGRAPY
WQPPVLPELETGEYYPLHPHTQMVNRVKVHPQMIIENAADPYHVQYVHKAANPATTASFEVAGYHLHATVNAHFGGGRAQ
TWLTPNGPVDAKIIYDNYSLGLGVVRFPSELVATVQVTGQTPVDEDYTDYFYTQASVREPGDTGDVPTGRAARFLALQKE
VIKQDFFTWENMKYLEKPNLAPEEAHDYAALRRWAHRFYPGPQPAPTDFGYTADGEPDPAAAKA

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG4638

COG function: function code PR; Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Rieske domain [H]

Homologues:

Organism=Caenorhabditis elegans, GI71983709, Length=355, Percent_Identity=25.9154929577465, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI161085896, Length=169, Percent_Identity=36.6863905325444, Blast_Score=110, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017941 [H]

Pfam domain/function: PF00355 Rieske [H]

EC number: NA

Molecular weight: Translated: 42759; Mature: 42759

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTGYGVQVARTVSDSAPDSAEDPSEREFGQAGIALSTYRFPTGWFIVAFGSDLAPGQV
CCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCCH
KRAHYFGEELVLFRTASGRVHVMDAYCQHLGANLGVGGTVEGENIVCPWHGWQWRGDGSN
HHHHHCCCEEEEEEECCCCEEEHHHHHHHHCCCCCCCCEECCCEEEECCCCEEEECCCCC
ALIPYSKIGCKNNVRIRTYPSMEWYGFVLAWHERHGRAPYWQPPVLPELETGEYYPLHPH
EECCHHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCH
TQMVNRVKVHPQMIIENAADPYHVQYVHKAANPATTASFEVAGYHLHATVNAHFGGGRAQ
HHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEEEEECCCCEE
TWLTPNGPVDAKIIYDNYSLGLGVVRFPSELVATVQVTGQTPVDEDYTDYFYTQASVREP
EEECCCCCCCEEEEEECCCCCCEEEECCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCC
GDTGDVPTGRAARFLALQKEVIKQDFFTWENMKYLEKPNLAPEEAHDYAALRRWAHRFYP
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCC
GPQPAPTDFGYTADGEPDPAAAKA
CCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVRTGYGVQVARTVSDSAPDSAEDPSEREFGQAGIALSTYRFPTGWFIVAFGSDLAPGQV
CCCCCCCEEEEEECCCCCCCCCCCCCHHHHCCCCEEEEEEECCCCEEEEEECCCCCCCCH
KRAHYFGEELVLFRTASGRVHVMDAYCQHLGANLGVGGTVEGENIVCPWHGWQWRGDGSN
HHHHHCCCEEEEEEECCCCEEEHHHHHHHHCCCCCCCCEECCCEEEECCCCEEEECCCCC
ALIPYSKIGCKNNVRIRTYPSMEWYGFVLAWHERHGRAPYWQPPVLPELETGEYYPLHPH
EECCHHHCCCCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEECCCCH
TQMVNRVKVHPQMIIENAADPYHVQYVHKAANPATTASFEVAGYHLHATVNAHFGGGRAQ
HHHHHHHHCCHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEEEEEEEEEEEEECCCCEE
TWLTPNGPVDAKIIYDNYSLGLGVVRFPSELVATVQVTGQTPVDEDYTDYFYTQASVREP
EEECCCCCCCEEEEEECCCCCCEEEECCCEEEEEEEEECCCCCCCCCCCEEEEECCCCCC
GDTGDVPTGRAARFLALQKEVIKQDFFTWENMKYLEKPNLAPEEAHDYAALRRWAHRFYP
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCC
GPQPAPTDFGYTADGEPDPAAAKA
CCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA