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The map label for this gene is ndk

Identifier: 41408366

GI number: 41408366

Start: 2534103

End: 2534513

Strand: Reverse

Name: ndk

Synonym: MAP2268c

Alternate gene names: 41408366

Gene position: 2534513-2534103 (Counterclockwise)

Preceding gene: 41408367

Following gene: 41408365

Centisome position: 52.48

GC content: 66.91

Gene sequence:

>411_bases
GTGACCGAACGGACATTGGTACTGATCAAGCCGGACGGCGTCCAGCGGCAGCTGGTGGGGGAGATCATCGGCCGGATCGA
GCGGAAGGGCCTCACCCTCGTCGCGCTGGAGCTGCGGCACGTCAGCCAAGATCTGGCCGCCCAGCATTACGCGGAGCACG
AGGGCAAGCCGTTCTTCGCGTCGTTGCTGGAGTTCATCACCTCCGGTCCGGTGGTGGCGGCCATCGTCGAGGGACCGCGG
GCGATCGCGGCGTTCCGGCAGCTCGCCGGGGGCACCGATCCGGTGGAGAAGGCGATTCCCGGCACCATCCGGGGCGATTT
CGGGTTGGAGACGCAGTTCAACCTGGTGCACGGGTCCGATTCGGTCGAGTCGGCGAAACGGGAAATCGGGCTCTGGTTTC
CCGACGCCTAG

Upstream 100 bases:

>100_bases
ACCGGGCTGTGGGCGCTGATCGCCTACTTCCGCGCCGAGGTCCGCCGCCGGCAGGGATGACGCCCGGCGTCTGGCCAGCT
GGTTATGTACGCTGTCCGCC

Downstream 100 bases:

>100_bases
AGCTGCGGCGATGCCGCCGCCTGCCGGGGGCGGGCGGTTCCGCCCGAGCCGGCGGCCTCAGGTGCGGGTGGACCGGTGCC
GTGATGTGGGATACTGATCT

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MTERTLVLIKPDGVQRQLVGEIIGRIERKGLTLVALELRHVSQDLAAQHYAEHEGKPFFASLLEFITSGPVVAAIVEGPR
AIAAFRQLAGGTDPVEKAIPGTIRGDFGLETQFNLVHGSDSVESAKREIGLWFPDA

Sequences:

>Translated_136_residues
MTERTLVLIKPDGVQRQLVGEIIGRIERKGLTLVALELRHVSQDLAAQHYAEHEGKPFFASLLEFITSGPVVAAIVEGPR
AIAAFRQLAGGTDPVEKAIPGTIRGDFGLETQFNLVHGSDSVESAKREIGLWFPDA
>Mature_135_residues
TERTLVLIKPDGVQRQLVGEIIGRIERKGLTLVALELRHVSQDLAAQHYAEHEGKPFFASLLEFITSGPVVAAIVEGPRA
IAAFRQLAGGTDPVEKAIPGTIRGDFGLETQFNLVHGSDSVESAKREIGLWFPDA

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=131, Percent_Identity=55.7251908396947, Blast_Score=149, Evalue=5e-37,
Organism=Homo sapiens, GI4557797, Length=132, Percent_Identity=53.030303030303, Blast_Score=146, Evalue=5e-36,
Organism=Homo sapiens, GI38045913, Length=132, Percent_Identity=53.030303030303, Blast_Score=146, Evalue=6e-36,
Organism=Homo sapiens, GI4826862, Length=131, Percent_Identity=51.1450381679389, Blast_Score=140, Evalue=3e-34,
Organism=Homo sapiens, GI66392227, Length=131, Percent_Identity=50.381679389313, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI66392205, Length=131, Percent_Identity=50.381679389313, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI4505409, Length=131, Percent_Identity=50.381679389313, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI66392192, Length=131, Percent_Identity=50.381679389313, Blast_Score=138, Evalue=2e-33,
Organism=Homo sapiens, GI66392203, Length=131, Percent_Identity=50.381679389313, Blast_Score=137, Evalue=2e-33,
Organism=Homo sapiens, GI37574614, Length=139, Percent_Identity=36.6906474820144, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI7019465, Length=139, Percent_Identity=36.6906474820144, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI5031951, Length=135, Percent_Identity=42.2222222222222, Blast_Score=90, Evalue=6e-19,
Organism=Homo sapiens, GI4505413, Length=136, Percent_Identity=33.8235294117647, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI30023828, Length=136, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=5e-13,
Organism=Homo sapiens, GI148839372, Length=135, Percent_Identity=31.1111111111111, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788866, Length=131, Percent_Identity=45.0381679389313, Blast_Score=123, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17506807, Length=132, Percent_Identity=50.7575757575758, Blast_Score=135, Evalue=5e-33,
Organism=Saccharomyces cerevisiae, GI6322783, Length=132, Percent_Identity=53.030303030303, Blast_Score=148, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45549037, Length=133, Percent_Identity=49.6240601503759, Blast_Score=145, Evalue=6e-36,
Organism=Drosophila melanogaster, GI18860097, Length=136, Percent_Identity=35.2941176470588, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 14757; Mature: 14626

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTERTLVLIKPDGVQRQLVGEIIGRIERKGLTLVALELRHVSQDLAAQHYAEHEGKPFFA
CCCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHH
SLLEFITSGPVVAAIVEGPRAIAAFRQLAGGTDPVEKAIPGTIRGDFGLETQFNLVHGSD
HHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCC
SVESAKREIGLWFPDA
HHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TERTLVLIKPDGVQRQLVGEIIGRIERKGLTLVALELRHVSQDLAAQHYAEHEGKPFFA
CCCEEEEECCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHCCCCCHHH
SLLEFITSGPVVAAIVEGPRAIAAFRQLAGGTDPVEKAIPGTIRGDFGLETQFNLVHGSD
HHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCEEEEEEECCC
SVESAKREIGLWFPDA
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA