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The map label for this gene is desA1 [H]

Identifier: 41408302

GI number: 41408302

Start: 2449462

End: 2450145

Strand: Reverse

Name: desA1 [H]

Synonym: MAP2204c

Alternate gene names: 41408302

Gene position: 2450145-2449462 (Counterclockwise)

Preceding gene: 41408303

Following gene: 41408301

Centisome position: 50.73

GC content: 62.57

Gene sequence:

>684_bases
ATGGACAACCGGGAGGGTTCCGTGCCCAAGGACCTGACTAACCTGCAGCTGCTGCATGAACTCGAGCCGGTGGTGGAGGG
GCTGCTCAACCGGCACCTGGCGAAGTTCAAGGAGTGGAACCCGCACGACTACGTGCCCTGGTCGGACGGCAAGAATTTCC
ACACCCGCGGCGGGCAGGATTGGGAGCCCGGCCAGACCCGGCTGCCCGACGTCGCGCAGGTGGCCATCGTCCAAAACCTG
CTGACCGAAGACAATCTGCCGTCGTATCACCGCGAAATCGCCATGAATTTCGGCATGGACGGCCCGTGGGGCCAGTGGGT
GAACCGCTGGACCGCGGAGGAGGCCAGGCACAGCACCGCGCTGCGCGATTACCTCGTGGTCACTCGATCGGTGGACCCGG
TGGAATTGGAGTTGCTGCGGCTCGAGCAAATGACCCGGGGCTTCAGCCCCGGCCAGAATCAGCAGGGCGACATGTTCGCC
GAGAGCCTGTTCGACTCGGTCATGTATGTCCTTACCTTTCTTGAAGGGTGTTCGGGGCCGTCGGCCTTAGGCTTCGAATT
GCCCAGGGACGTCGGGTATGGCTTTCATGTGGTTGCTGTGTTGGATGGCCGAAGGAGATTGGCCGCCCGGCGTCCCGCGA
CGACTCGACCGCTAATTGAGAGATGCGATTGGATCGCTGTGTAA

Upstream 100 bases:

>100_bases
GGTTCGGCGCTAAGGGACTTTCGGCCCTAGGTGGTCGCCTCCGCCGCGTGTCATCTTCATGTAACCGCATGACACAGATA
CATGCGGGCTGCCGACCGCG

Downstream 100 bases:

>100_bases
GGACACGTCGGCGTGGTCGTCTGCTGGGTTGATCTGGACAATGACGGTTACGGAGGTGGTTGTGGCACAACCTGTCTGGG
CGGGCGTGGACGCCGGTAAG

Product: hypothetical protein

Products: NA

Alternate protein names: DES; Putative acyl-ACP desaturase desA1 [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDNREGSVPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTRGGQDWEPGQTRLPDVAQVAIVQNL
LTEDNLPSYHREIAMNFGMDGPWGQWVNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQQGDMFA
ESLFDSVMYVLTFLEGCSGPSALGFELPRDVGYGFHVVAVLDGRRRLAARRPATTRPLIERCDWIAV

Sequences:

>Translated_227_residues
MDNREGSVPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTRGGQDWEPGQTRLPDVAQVAIVQNL
LTEDNLPSYHREIAMNFGMDGPWGQWVNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQQGDMFA
ESLFDSVMYVLTFLEGCSGPSALGFELPRDVGYGFHVVAVLDGRRRLAARRPATTRPLIERCDWIAV
>Mature_227_residues
MDNREGSVPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTRGGQDWEPGQTRLPDVAQVAIVQNL
LTEDNLPSYHREIAMNFGMDGPWGQWVNRWTAEEARHSTALRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQQGDMFA
ESLFDSVMYVLTFLEGCSGPSALGFELPRDVGYGFHVVAVLDGRRRLAARRPATTRPLIERCDWIAV

Specific function: Could be involved in mycobacterial fatty acid biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005067
- InterPro:   IPR009078
- InterPro:   IPR012348 [H]

Pfam domain/function: PF03405 FA_desaturase_2 [H]

EC number: NA

Molecular weight: Translated: 25883; Mature: 25883

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNREGSVPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTRGGQD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
WEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQWVNRWTAEEARHSTA
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQQGDMFAESLFDSVMYVLTFLEGCSGP
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SALGFELPRDVGYGFHVVAVLDGRRRLAARRPATTRPLIERCDWIAV
CCCCCCCCHHCCCCEEEEEEECCHHHHHHCCCCCCHHHHHHCCCCCC
>Mature Secondary Structure
MDNREGSVPKDLTNLQLLHELEPVVEGLLNRHLAKFKEWNPHDYVPWSDGKNFHTRGGQD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
WEPGQTRLPDVAQVAIVQNLLTEDNLPSYHREIAMNFGMDGPWGQWVNRWTAEEARHSTA
CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LRDYLVVTRSVDPVELELLRLEQMTRGFSPGQNQQGDMFAESLFDSVMYVLTFLEGCSGP
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
SALGFELPRDVGYGFHVVAVLDGRRRLAARRPATTRPLIERCDWIAV
CCCCCCCCHHCCCCEEEEEEECCHHHHHHCCCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]