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The map label for this gene is mbtB

Identifier: 41408275

GI number: 41408275

Start: 2417948

End: 2421445

Strand: Reverse

Name: mbtB

Synonym: MAP2177c

Alternate gene names: 41408275

Gene position: 2421445-2417948 (Counterclockwise)

Preceding gene: 41408278

Following gene: 41408274

Centisome position: 50.14

GC content: 71.84

Gene sequence:

>3498_bases
GTGGTGCACGCCCCGGCACGCTCGGAGGACATCCGGGAAGAGGTGGCTGAACTGCTCGGCGTCGACGTCGATGCAGTTCA
GCCGGGTAGCAACCTCATCGGCCAGGGCTTGGACTCGATCCGGATCATGACCCTGGCCGGCCGCTGGCGGCGCCGGGGCA
TCGCCGTCGACTTCGCCACGCTGGCCGAGACGCCCACCATCGAGGCCTGGGCACAACTGGTCACCGCCGGCCGCCAGGAC
ACCGATTCGGCGGCCCCGCCCGCCGATTCATCCGGGGACCCGTCGGGCGAGACCGAGCCGTTTGCCCTGGCCCCGATGCA
GCACGCCATGTGGGTGGGCCGCCAGGACAACCAGCAGCTCGGCGGGGTGGCCGGGCACCTCTACGTGGAGTTCGACGCCG
GCCTTCTCGACTCGGGCCGGCTGCGGGCGGCGGCCACCGCGCTGGCCCGTCGCCACCCGATGCTGCGTGTGCGGTTTCTG
CCCGACGGCACCCAGTGCATCACCCCGGCGGTGGAATGCGGTGACTTCCCGGTGCACGTCGAGGATCTGCGCGAGCTGGG
CACCGACGAGGTCGAGCGGCGGCTCACCGCGCTGCGCGAGGCCAAATCGCACCAGCAACTCGACGGCGCGGTGTTCGAGC
TGACCGTGACCCTGCTGCCGGGTGGGCGGTCGCGGTTGCACGTCGATCTGGACATGCAAGCCGCCGACGCGATGAGCTAT
CGCACCCTGATGGCCGATCTGGCGGCGCTGTACCGCGGATGCGATCTGCCTGAACTGAGCTACACCTACCGGCAGTACCG
CCACGCCGTCGAGGCGCAGGACGCGCAGCCGCAACCGCGCCGGGACGCCGACCGCGACTGGTGGGCACGCCGTCTGCCGG
AGCTGCCGGATCCGCCGGCCCTACCGATCACCGCCGGCCGCGGCGCAAACCGCAGCACCCGGCGCTGGCACTGGCTGGAT
CCGCAGACCCGCGACGCGCTGTTCGCCCGCGCCCAAGCGCGCGGCATCACCCCGGCGATGGCGCTGGCCGCGGGGTTCGC
CAACACGCTGGCCCGCTGGTCGTCCAATTCCCGCTTCCTGCTGAATGTTCCGCTGTTCGGGCGGCAGCCCTTGCACCCGG
ACGTCGACGCGCTGGTCGGCGACTTCACCTCCTCGCTGCTGCTCGACGTCGACCTGGTCGGCGCGCACACCGCGGCGGCG
CGCGCTCAGGTGGTGCAGGACGCGATGCGCACGGCCGCCGCCCATTCCGCCTACTCGGGGTTGTCGGTGCTGCGCGACCT
GAGCCGTCATCGCGGCACCCAGGTGCTGGCGCCGGTGGTTTTCACCAGCGCGCTGGGACTCGGCGAACTGTTCAGCCCGG
AGGTCACCGGCCAGTTCGGCACGCCGGCCTGGATCATCTCTCAGGGACCGCAGGTGCTGCTCGACGCCCAGGTCACCGAA
TTCGACGGCGGCGTGCTGGTGAATTGGGATGTGCGGGAAGGGTTTTTCCCACCCGGGGTGATCGACGCCATGTTCGCCTA
CCACATCGACGAGCTGCTGCGGTTGGCCTCCGCCGATGACGCCTGGGACGCGCCGGGTCCCGCGGCGCTGCCCGAGGCGC
AGCGCGCCGTGCGCGAGGCGATCAACGGGCGCACCGCGCCGCCCAGCGGAGAAGCCTTGCACGACAGGTTCTTTCGGCAA
GCCGAGCGGCAGCCGGATGCGCCCGCGGTGTTCGCCGGTTCCGGCGACCTCAGCTACGCGCAGCTGCGCGATCAGGCCCT
GGCGGTGGCGGCGGCGCTGCGCGCGGCCGGCGCCGGCGCCGGGGACACCGTCGCGGTGGTCGGCCCGAAGAGCGCCGAGC
AGATCCCGGCGGTGCTGGGCATCCTGTCCGTCGGCGCCGCCTATCTGCCGATCGGGGCCGACCAGCCCCGCGATCGCGCC
GAGCGCATCCTGCAATCCGGCCGGGTGCGCCTGGCCCTGGTGTGCGGCGGGCGGCAGCTGTCGCTGCCGGTGCCCGGGCT
GGTCCTTGCCGACGTGCTGGGCGGTGCTCCCGCGGACGCCGAGATCGCCTGCGCGAGAGTCGATCCCGGCGAGCTCGCCT
ACGTGTTGTTCACCTCGGGGTCGACCGGAGAGCCGAAGGGTGTCGAAGTCACCCACGATGCCGCGATGAACACCGTGGAA
TTCATCGGCCGCCACTTCGAGATCGGCCCCGCGGATCGATGCCTGGCCCTGTCGACCCTGGAAGGCGACATCTCGGTGAT
GGACGTGTTCGTCACGTTGCGCACCGGCGGCGCCATCGTGGTGGTCGACGAGGCGCAGCGGCGTGACCCCGATGCGTGGG
CCCGGCTGATCGACACCCACCGCGTCACGGTGCTGCATTTCATGCCCGGATGGCTGGAGATGCTGGTCGAGGTCGGCCGC
GGGCGGCTGTCCTCGGTGCGGGTGGTGCCCACCGGCGGCGACTGGGTGCGGCCCGAGGTGGTGCGCAGGCTGCGGGCCGA
AGCGCCCGGCCTGCGGTTCGCCGGCCTCGGCGGGGCGACCGAAACACCGGTGCACAACACGATTTTCGAGGTGACCGAAC
CGATCCCGGCGGACTGGACGGCGCTGCCGTTCGGCGTCCCGCTGCCCAACAACGTCTGCCGCGTCGTCGGCGACACCGGG
GGCGACTGTCCGGAGTGGGTGCCCGGGGAGCTCTGGGTGTCCGGGCGCGGCATCGCCCGCGGTTACCGCGGCCGCCCCGA
TCTCACCGCGCAGCGCTTCGTCGAGCACGACGGCCGAACCTCGTATCGCACCGGCGATTTGGTTCGCTACCGGCCGGACG
GAACCCTCGAATTCGTCGGGCGCGCCGACCACCGCGTCAAGATCAGCGGGTACCGCGTCGAGCTGGGTGAGATCGAGTCC
GCGCTACGGCGGGTGCCCGGGGTGCGCACGGCGGTGGCCGCCCTGATCGCCGGGGCGGGCGAATCCGACGTGCTGGCCGC
CCAAGTGGGCACCGACGACCCCGCCCTGACCGGCGAGCAGGTCCGGCAATACCTCGCCGACCTCGTTCCCGCGCACATGA
TCCCGCGCCACGTCGCGGTGGTGGAGCGGATCGGCTTCACCGCGGCCGGCAAGCTCGATCGCCGGGCCGTGGCACGCGAA
TTGCACAGCGTCGTCGGGCAATCGCACTCGCCCGGCCACCGCGCGGCGTCCACACCGCTGGAAGGCGCGCTGGCGCTGAT
CCTGGGCGATCTGCTCGGGCGGGACGACGTCGGCGTCGACGACGACTTCTTCGCGCTCGGCGGTGATTCGGTGCTCGCCA
CCCAGGCGGTGGCGCGAATCCGGGCCTGGCTGGACGCGCCCGACGTCATGGTCGCCGACATGTTCGCCAACCGGACGGTG
TCGGCGCTGGCCGCGGTGCTACGTGCCGCCGAGGACGACCCCGACCGGCTCGACCACGTCGCCGAGTTGTATCTGGAGGT
GATCGGCATGGATGCTGAATCGGTGCTGACGGCTACCCGGCAAACTACGAAATCGTAA

Upstream 100 bases:

>100_bases
TCTAAGCGGGCTTCGAACGGGGCTAGTAGCGGGGACGCAGGGAGTAAGGATAGGGTAACCAAATCATTTAAGGGCAGCCT
GTGCTAATTCAGGGAGGTCT

Downstream 100 bases:

>100_bases
CCGGTGCAATGACATTGAATAACATCGCTACCATGCCCTCCGCCTTCCCGTCCTGGATCAAGCTGGCCCCGGGCCGCGGC
GGCCCGGCGTCCGGGACGGG

Product: MbtB

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Mycobactin synthetase protein B

Number of amino acids: Translated: 1165; Mature: 1165

Protein sequence:

>1165_residues
MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATLAETPTIEAWAQLVTAGRQD
TDSAAPPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQLGGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFL
PDGTQCITPAVECGDFPVHVEDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSY
RTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPALPITAGRGANRSTRRWHWLD
PQTRDALFARAQARGITPAMALAAGFANTLARWSSNSRFLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAA
RAQVVQDAMRTAAAHSAYSGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQVTE
FDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVREAINGRTAPPSGEALHDRFFRQ
AERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGAGAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRA
ERILQSGRVRLALVCGGRQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMNTVE
FIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLIDTHRVTVLHFMPGWLEMLVEVGR
GRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLGGATETPVHNTIFEVTEPIPADWTALPFGVPLPNNVCRVVGDTG
GDCPEWVPGELWVSGRGIARGYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVELGEIES
ALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIPRHVAVVERIGFTAAGKLDRRAVARE
LHSVVGQSHSPGHRAASTPLEGALALILGDLLGRDDVGVDDDFFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTV
SALAAVLRAAEDDPDRLDHVAELYLEVIGMDAESVLTATRQTTKS

Sequences:

>Translated_1165_residues
MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATLAETPTIEAWAQLVTAGRQD
TDSAAPPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQLGGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFL
PDGTQCITPAVECGDFPVHVEDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSY
RTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPALPITAGRGANRSTRRWHWLD
PQTRDALFARAQARGITPAMALAAGFANTLARWSSNSRFLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAA
RAQVVQDAMRTAAAHSAYSGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQVTE
FDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVREAINGRTAPPSGEALHDRFFRQ
AERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGAGAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRA
ERILQSGRVRLALVCGGRQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMNTVE
FIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLIDTHRVTVLHFMPGWLEMLVEVGR
GRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLGGATETPVHNTIFEVTEPIPADWTALPFGVPLPNNVCRVVGDTG
GDCPEWVPGELWVSGRGIARGYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVELGEIES
ALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIPRHVAVVERIGFTAAGKLDRRAVARE
LHSVVGQSHSPGHRAASTPLEGALALILGDLLGRDDVGVDDDFFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTV
SALAAVLRAAEDDPDRLDHVAELYLEVIGMDAESVLTATRQTTKS
>Mature_1165_residues
MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFATLAETPTIEAWAQLVTAGRQD
TDSAAPPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQLGGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFL
PDGTQCITPAVECGDFPVHVEDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSY
RTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPALPITAGRGANRSTRRWHWLD
PQTRDALFARAQARGITPAMALAAGFANTLARWSSNSRFLLNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAA
RAQVVQDAMRTAAAHSAYSGLSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQVTE
FDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVREAINGRTAPPSGEALHDRFFRQ
AERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGAGAGDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRA
ERILQSGRVRLALVCGGRQLSLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMNTVE
FIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLIDTHRVTVLHFMPGWLEMLVEVGR
GRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLGGATETPVHNTIFEVTEPIPADWTALPFGVPLPNNVCRVVGDTG
GDCPEWVPGELWVSGRGIARGYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVELGEIES
ALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIPRHVAVVERIGFTAAGKLDRRAVARE
LHSVVGQSHSPGHRAASTPLEGALALILGDLLGRDDVGVDDDFFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTV
SALAAVLRAAEDDPDRLDHVAELYLEVIGMDAESVLTATRQTTKS

Specific function: Involved in the initial steps of the mycobactin biosynthetic pathway. Putatively couples activated salicylic acid with serine or threonine and cyclizes this precursor to the hydroxyphenyloxazoline ring system present in this class of siderophores

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 acyl carrier domains

Homologues:

Organism=Homo sapiens, GI45580730, Length=425, Percent_Identity=25.6470588235294, Blast_Score=101, Evalue=4e-21,
Organism=Homo sapiens, GI38505220, Length=561, Percent_Identity=23.8859180035651, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI157311624, Length=515, Percent_Identity=21.9417475728155, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI157311622, Length=515, Percent_Identity=21.9417475728155, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI58082049, Length=515, Percent_Identity=21.9417475728155, Blast_Score=81, Evalue=5e-15,
Organism=Escherichia coli, GI1786801, Length=599, Percent_Identity=31.0517529215359, Blast_Score=237, Evalue=3e-63,
Organism=Escherichia coli, GI1786810, Length=522, Percent_Identity=26.4367816091954, Blast_Score=100, Evalue=6e-22,
Organism=Escherichia coli, GI1788107, Length=546, Percent_Identity=22.7106227106227, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI145693145, Length=534, Percent_Identity=23.4082397003745, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17556356, Length=588, Percent_Identity=23.8095238095238, Blast_Score=114, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=540, Percent_Identity=22.4074074074074, Blast_Score=83, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17559526, Length=369, Percent_Identity=24.390243902439, Blast_Score=79, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319591, Length=678, Percent_Identity=24.3362831858407, Blast_Score=147, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24648676, Length=669, Percent_Identity=24.2152466367713, Blast_Score=125, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18859661, Length=539, Percent_Identity=22.8200371057514, Blast_Score=73, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24581924, Length=357, Percent_Identity=24.3697478991597, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MBTB_MYCPA (Q73XY1)

Other databases:

- EMBL:   AE016958
- RefSeq:   NP_961111.1
- HSSP:   P0ADI4
- ProteinModelPortal:   Q73XY1
- EnsemblBacteria:   EBMYCT00000039255
- GeneID:   2720194
- GenomeReviews:   AE016958_GR
- KEGG:   mpa:MAP2177c
- NMPDR:   fig|262316.1.peg.2177
- GeneTree:   EBGT00050000015136
- HOGENOM:   HBG676528
- OMA:   TLMADLA
- ProtClustDB:   CLSK791816
- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR013624
- InterPro:   IPR006163
- InterPro:   IPR006162
- Gene3D:   G3DSA:1.10.1200.10
- TIGRFAMs:   TIGR01733

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF08415 NRPS; PF00550 PP-binding; SSF47336 ACP_like

EC number: 2.7.7.- [C]

Molecular weight: Translated: 125045; Mature: 125045

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50075 ACP_DOMAIN; PS00455 AMP_BINDING; PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFAT
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEEHHHHHHCCEEEEHHH
LAETPTIEAWAQLVTAGRQDTDSAAPPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQL
HCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCCHH
GGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFLPDGTQCITPAVECGDFPVHV
CCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHCCCCCEEH
EDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSY
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEEEEEECCHHHHHHHH
RTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
LPITAGRGANRSTRRWHWLDPQTRDALFARAQARGITPAMALAAGFANTLARWSSNSRFL
CEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEE
LNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAARAQVVQDAMRTAAAHSAYSG
EECCCCCCCCCCCCHHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQVTE
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEECCCCCEEEEEEEEE
FDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVREA
CCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
INGRTAPPSGEALHDRFFRQAERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGAGA
HCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
GDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRAERILQSGRVRLALVCGGRQL
CCEEEEECCCCHHHHHHHHHHHHHCHHEECCCCCCCHHHHHHHHHCCCEEEEEEECCEEE
SLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMNTVE
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHH
FIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLIDTH
HHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHCC
RVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLGGAT
CEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCC
ETPVHNTIFEVTEPIPADWTALPFGVPLPNNVCRVVGDTGGDCPEWVPGELWVSGRGIAR
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCEEECCCCCCC
GYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVELGEIES
CCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCCEEEEEEEEEEHHHHHH
ALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIPRHVAV
HHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VERIGFTAAGKLDRRAVARELHSVVGQSHSPGHRAASTPLEGALALILGDLLGRDDVGVD
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
DDFFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTVSALAAVLRAAEDDPDRLDHV
CCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AELYLEVIGMDAESVLTATRQTTKS
HHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MVHAPARSEDIREEVAELLGVDVDAVQPGSNLIGQGLDSIRIMTLAGRWRRRGIAVDFAT
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCEEEEEEHHHHHHCCEEEEHHH
LAETPTIEAWAQLVTAGRQDTDSAAPPADSSGDPSGETEPFALAPMQHAMWVGRQDNQQL
HCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECCHHHHHHCCCCCCCHH
GGVAGHLYVEFDAGLLDSGRLRAAATALARRHPMLRVRFLPDGTQCITPAVECGDFPVHV
CCEEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCHHHCCHHHCCCCCEEH
EDLRELGTDEVERRLTALREAKSHQQLDGAVFELTVTLLPGGRSRLHVDLDMQAADAMSY
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCEEEEEECCHHHHHHHH
RTLMADLAALYRGCDLPELSYTYRQYRHAVEAQDAQPQPRRDADRDWWARRLPELPDPPA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCCC
LPITAGRGANRSTRRWHWLDPQTRDALFARAQARGITPAMALAAGFANTLARWSSNSRFL
CEEECCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEE
LNVPLFGRQPLHPDVDALVGDFTSSLLLDVDLVGAHTAAARAQVVQDAMRTAAAHSAYSG
EECCCCCCCCCCCCHHHHHHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LSVLRDLSRHRGTQVLAPVVFTSALGLGELFSPEVTGQFGTPAWIISQGPQVLLDAQVTE
HHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCCCCCCCCCCCCEEEECCCCCEEEEEEEEE
FDGGVLVNWDVREGFFPPGVIDAMFAYHIDELLRLASADDAWDAPGPAALPEAQRAVREA
CCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHH
INGRTAPPSGEALHDRFFRQAERQPDAPAVFAGSGDLSYAQLRDQALAVAAALRAAGAGA
HCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCC
GDTVAVVGPKSAEQIPAVLGILSVGAAYLPIGADQPRDRAERILQSGRVRLALVCGGRQL
CCEEEEECCCCHHHHHHHHHHHHHCHHEECCCCCCCHHHHHHHHHCCCEEEEEEECCEEE
SLPVPGLVLADVLGGAPADAEIACARVDPGELAYVLFTSGSTGEPKGVEVTHDAAMNTVE
CCCCCHHHHHHHHCCCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHH
FIGRHFEIGPADRCLALSTLEGDISVMDVFVTLRTGGAIVVVDEAQRRDPDAWARLIDTH
HHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCEEEEECCCCCCCHHHHHHHHHCC
RVTVLHFMPGWLEMLVEVGRGRLSSVRVVPTGGDWVRPEVVRRLRAEAPGLRFAGLGGAT
CEEEEECCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCEEEECCCCC
ETPVHNTIFEVTEPIPADWTALPFGVPLPNNVCRVVGDTGGDCPEWVPGELWVSGRGIAR
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCHHEEECCCCCCCCCCCCCCEEECCCCCCC
GYRGRPDLTAQRFVEHDGRTSYRTGDLVRYRPDGTLEFVGRADHRVKISGYRVELGEIES
CCCCCCCHHHHHHHHCCCCCCCCCCCEEEECCCCCEEEECCCCCEEEEEEEEEEHHHHHH
ALRRVPGVRTAVAALIAGAGESDVLAAQVGTDDPALTGEQVRQYLADLVPAHMIPRHVAV
HHHHCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VERIGFTAAGKLDRRAVARELHSVVGQSHSPGHRAASTPLEGALALILGDLLGRDDVGVD
HHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
DDFFALGGDSVLATQAVARIRAWLDAPDVMVADMFANRTVSALAAVLRAAEDDPDRLDHV
CCEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
AELYLEVIGMDAESVLTATRQTTKS
HHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA