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The map label for this gene is ybeX [C]

Identifier: 41408244

GI number: 41408244

Start: 2376369

End: 2377679

Strand: Reverse

Name: ybeX [C]

Synonym: MAP2146c

Alternate gene names: 41408244

Gene position: 2377679-2376369 (Counterclockwise)

Preceding gene: 41408245

Following gene: 41408243

Centisome position: 49.23

GC content: 67.28

Gene sequence:

>1311_bases
ATGACCGGCTGGTCTGAGTTGCTGGGTGCGGTGGCGTTGATCGCCTTGGGCGGCCTGTTCGCGGCGATCGATGCGGCCAT
CAGCACGGTGTCGCTGGCCCGGGTGCAGGAGCTGGTGCGTGACGAGCGGCCCGGCGCGGTGGCGCTGTCCAAGGTGATGT
CCGAGCGGCCCCGCTACATCAACCTGGTGGTGCTGCTACGGATCACCTGCGAGATCACCGCGACCGTGCTGCTGGTGGTG
TTTCTCTACGACAACTTCGGGCTCAGGTGGGGGCTGTTCGGCGCCGCCGCCATCATGGTGGTGACCAGTTTCGTGGTCAT
GGGGGTGGGTCCGCGCACCCTGGGCCGTCAGAACGCCTATTCCATCGCGTTGACGACAGTCCTTCCGCTGCAAGTCATTT
CATGGCTGCTGATGCCGATCAGCCGGTTGCTGGTGGTGCTGGGTAATGCGGTCACTCCCGGCCGGGGGTTGCGCAACGGG
CCGTTTGCCTCTGAGATCGAGCTGCGCGAGGTCGTCGACCTGGCCCAGCAACGCGGCGTGGTCGCCGCCGAGGAACGCCG
CATGATCCAGTCGGTGTTCGAACTCGGTGACACCCCGGCCCGTGAGGTGATGGTGCCGCGCACCGAGATGATCTGGATCG
AGAGCGACAAATCGGCGAGCCAGGCGATCAACCTGGCGGTGCGCAGCGGGCACTCGCGCATCCCGGTGATCGGCGAGAAC
GTCGACGACATCGTCGGGGTGGTGTACCTCAAAGACCTTGTGCAGCAGGCGCTCTTACCCGGCGGCAGCGGCCGGGCCAC
ACCGGTGTCGCAGGTGATGCGGCCCGCCGTCTTCGTGCCGGACTCCAAGCCGCTGGATGCGTTGCTGCGGGAGATGCAGC
GCGACCGGAACCACATGGCGCTGCTGGTCGACGAGTACGGGGCGATCGCCGGGCTGGTCAGCATCGAAGACGTGCTGGAG
GAGATCGTCGGCGAGATCGCCGACGAATACGACCAGGCCGAGACCGCACCGATAGAAGACCTGGGCGACAAGCGGTTCCG
CGTGTCGGCGCGGCTGCCCATCGAAGACCTCGGCGAGCTCTACGGCGTGGAGTTCGACGACGATCTCGATGTCGACACGG
TGGGCGGCCTGCTCGCCCTGGAGCTGGGTCGGGTGCCGCTGCCCGGCGCCGAGGTGATATCGCACGGCTTGCGGCTGCAC
GCCGAAGGCGGCACCGATCACCGCGGCCGGGTGCGGGTGGGCACCGTGCTGCTCAGCCCGGTCGAATCCGACGGGTCACC
CGACGGTGAGGAACCCGAGCATCATGACTGA

Upstream 100 bases:

>100_bases
GGGGTCTGGCGCTGCGGTTCGGGGGCTTCGCGGTGGTGGTGGGCGTGATCGCCTGGCTGCTGGCCCGCCGGAGCCGGTCC
GAGGAGCAGAACGCCGATTC

Downstream 100 bases:

>100_bases
ATTCCGTTCCGGCTTCGTGTGTTTGGTCGGGCGCCCCAACACCGGGAAGTCCACGCTGACCAACGCGCTGGTCGGCACCA
AGGTCGCGATCACCTCGATG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALSKVMSERPRYINLVVLLRITCEITATVLLVV
FLYDNFGLRWGLFGAAAIMVVTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPISRLLVVLGNAVTPGRGLRNG
PFASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPAREVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGEN
VDDIVGVVYLKDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLE
EIVGEIADEYDQAETAPIEDLGDKRFRVSARLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
AEGGTDHRGRVRVGTVLLSPVESDGSPDGEEPEHHD

Sequences:

>Translated_436_residues
MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALSKVMSERPRYINLVVLLRITCEITATVLLVV
FLYDNFGLRWGLFGAAAIMVVTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPISRLLVVLGNAVTPGRGLRNG
PFASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPAREVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGEN
VDDIVGVVYLKDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLE
EIVGEIADEYDQAETAPIEDLGDKRFRVSARLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLH
AEGGTDHRGRVRVGTVLLSPVESDGSPDGEEPEHHD
>Mature_435_residues
TGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALSKVMSERPRYINLVVLLRITCEITATVLLVVF
LYDNFGLRWGLFGAAAIMVVTSFVVMGVGPRTLGRQNAYSIALTTVLPLQVISWLLMPISRLLVVLGNAVTPGRGLRNGP
FASEIELREVVDLAQQRGVVAAEERRMIQSVFELGDTPAREVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGENV
DDIVGVVYLKDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMALLVDEYGAIAGLVSIEDVLEE
IVGEIADEYDQAETAPIEDLGDKRFRVSARLPIEDLGELYGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLHA
EGGTDHRGRVRVGTVLLSPVESDGSPDGEEPEHHD

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=398, Percent_Identity=26.8844221105528, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI94681046, Length=264, Percent_Identity=28.030303030303, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI40068055, Length=355, Percent_Identity=23.6619718309859, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI40068053, Length=355, Percent_Identity=23.6619718309859, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI40068049, Length=155, Percent_Identity=34.1935483870968, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786879, Length=223, Percent_Identity=36.322869955157, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87082033, Length=265, Percent_Identity=29.811320754717, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI145693175, Length=387, Percent_Identity=24.5478036175711, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790664, Length=334, Percent_Identity=21.8562874251497, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788119, Length=209, Percent_Identity=32.0574162679426, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47135; Mature: 47004

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALSKVMSERPRYI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
NLVVLLRITCEITATVLLVVFLYDNFGLRWGLFGAAAIMVVTSFVVMGVGPRTLGRQNAY
EHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
SIALTTVLPLQVISWLLMPISRLLVVLGNAVTPGRGLRNGPFASEIELREVVDLAQQRGV
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
VAAEERRMIQSVFELGDTPAREVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGEN
HHHHHHHHHHHHHHCCCCCCHHEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEECCC
VDDIVGVVYLKDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEECCCCCCHHHHHHHHHHCCCCEE
LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPIEDLGDKRFRVSARLPIEDLGEL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCHHHHHHH
YGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLHAEGGTDHRGRVRVGTVLLSP
HCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCCCCCCEEEEEEEEEC
VESDGSPDGEEPEHHD
CCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TGWSELLGAVALIALGGLFAAIDAAISTVSLARVQELVRDERPGAVALSKVMSERPRYI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEE
NLVVLLRITCEITATVLLVVFLYDNFGLRWGLFGAAAIMVVTSFVVMGVGPRTLGRQNAY
EHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCC
SIALTTVLPLQVISWLLMPISRLLVVLGNAVTPGRGLRNGPFASEIELREVVDLAQQRGV
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
VAAEERRMIQSVFELGDTPAREVMVPRTEMIWIESDKSASQAINLAVRSGHSRIPVIGEN
HHHHHHHHHHHHHHCCCCCCHHEECCCCEEEEEECCCCHHHHHHHHHHCCCCCCCEECCC
VDDIVGVVYLKDLVQQALLPGGSGRATPVSQVMRPAVFVPDSKPLDALLREMQRDRNHMA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCEEECCCCCCHHHHHHHHHHCCCCEE
LLVDEYGAIAGLVSIEDVLEEIVGEIADEYDQAETAPIEDLGDKRFRVSARLPIEDLGEL
EEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCEEEEEECCCHHHHHHH
YGVEFDDDLDVDTVGGLLALELGRVPLPGAEVISHGLRLHAEGGTDHRGRVRVGTVLLSP
HCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCCCCCCEEEEEEEEEC
VESDGSPDGEEPEHHD
CCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]