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The map label for this gene is rocD1

Identifier: 41408192

GI number: 41408192

Start: 2315642

End: 2316880

Strand: Reverse

Name: rocD1

Synonym: MAP2094c

Alternate gene names: 41408192

Gene position: 2316880-2315642 (Counterclockwise)

Preceding gene: 41408193

Following gene: 41408191

Centisome position: 47.97

GC content: 70.06

Gene sequence:

>1239_bases
ATGACGATTCTGGACGGGCAGCTCACCGCGACCCGCGTGGATTCCGCGATCAGGCTGGCGGAAAAGCGTGCCGCGCACAA
CTATTCGCCGTTACCGATCGTCGCCGCGAGCGCGCAGGGGGCGTGGATCACCGATGTCGACGGCCGACGCTACCTGGACT
GCCTGTCCGCCTATTCCGCGGTGAACTTCGGCCACCGTCACCCCGAGATCGTCGCCACCGCCCATGCGCAGCTGGACACC
GTCACCCTGGTCAGCCGCGCGGTCCATTCCGACAAGCTCGGGCCGTTCTGCGCGGCGCTCGCCTACCTGTGCGACAAGGA
CATGGTGCTGCCGATGAATTCGGGCGCCGAAGCCGTGGAAAGCGGCCTCAAGGTGGCCCGCAAGTGGGGGGCCGAGGTCA
AGGGGGTTCCCGCCGGCCAGGCCAATATCATCGTGGCGGACAACAACTTCCACGGCCGCACCATCAGCATCGTCAGCTTC
TCCTCGGACGCCGCGGCGCGGGACGGGTTCGGCCCCTTCACGCCGGGATTCCGCTCGGTGCCGTTCGGCGATGCCGGCAC
GCTGGCCCAGGCGATCGACGACAACACCGTCGCGGTGCTGCTGGAGCCGATTCAGGGTGAGGCCGGCATCGTCGTCCCGC
CCGACGACTACCTGCCGGCCGTCCGCGCGCTGTGCAGCGAGCACAACGTGCTGATGATCGCCGACGAGATTCAATCCGGC
CTGGCGCGTACCGGTTACACGTTTGCCTGCGACCGGTGGCGGGTGGTGCCCGACGTCTACCTGCTGGGCAAAGCCCTGGG
CGGCGGGGTGGTTCCGCTGTCGGCGGTGGTGGCCGACCGCGAGATCCTCGGCGTGTTGCATCCCGGCGAGCACGGCTCCA
CCTTCGGCGGCAACCCGCTGGCCGCCGCGATCGGCACCACCGTGGTGTCCATGCTGGCCCGCGGCGAGTACCAGGCTCGC
GCGACCGCGCTGGGCGCGCACCTGCAGCGGCGGCTGCGGGCGCTGGTCGGTCACGGGGTGGACGAGGTGCGCGGCCTGGG
GTTGTGGGCAGGGGTGGACATCGACCCGTCGCTGGGCAGCGGCCGGGAGATGAGCCTGCGGCTGGCCGAGCGGGGCGTGC
TGGTGAAGGACACGCATGGCGCGACCTTGCGCTTCGCGCCGCCTCTGGTGGTCACCGCGCAGGAGATCGACTGGGCGGTC
GGCCAGCTTGCTGCGGTGTTGCGGGAGGCTGCTTCATAA

Upstream 100 bases:

>100_bases
CCCAATTGCGCCGGGCGGGGTTCGAGCCGATAGGCGTCGATTTGTCCGAGCTGCTCAAAGGCGGCGGCTCCGTCAAGTGC
TGCACATTGGAGGTTTTCCC

Downstream 100 bases:

>100_bases
TCAGCTGACCCGGCAACAGGAGGGGCAATTGCCAGCCACGCCGATCGGCTTGAGAGCACAGCTGCTGCGACGGCGCCCGG
TGGTGGGCGCACACGTGGCC

Product: RocD1

Products: NA

Alternate protein names: OAT; Ornithine--oxo-acid aminotransferase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MTILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWITDVDGRRYLDCLSAYSAVNFGHRHPEIVATAHAQLDT
VTLVSRAVHSDKLGPFCAALAYLCDKDMVLPMNSGAEAVESGLKVARKWGAEVKGVPAGQANIIVADNNFHGRTISIVSF
SSDAAARDGFGPFTPGFRSVPFGDAGTLAQAIDDNTVAVLLEPIQGEAGIVVPPDDYLPAVRALCSEHNVLMIADEIQSG
LARTGYTFACDRWRVVPDVYLLGKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPLAAAIGTTVVSMLARGEYQAR
ATALGAHLQRRLRALVGHGVDEVRGLGLWAGVDIDPSLGSGREMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEIDWAV
GQLAAVLREAAS

Sequences:

>Translated_412_residues
MTILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWITDVDGRRYLDCLSAYSAVNFGHRHPEIVATAHAQLDT
VTLVSRAVHSDKLGPFCAALAYLCDKDMVLPMNSGAEAVESGLKVARKWGAEVKGVPAGQANIIVADNNFHGRTISIVSF
SSDAAARDGFGPFTPGFRSVPFGDAGTLAQAIDDNTVAVLLEPIQGEAGIVVPPDDYLPAVRALCSEHNVLMIADEIQSG
LARTGYTFACDRWRVVPDVYLLGKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPLAAAIGTTVVSMLARGEYQAR
ATALGAHLQRRLRALVGHGVDEVRGLGLWAGVDIDPSLGSGREMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEIDWAV
GQLAAVLREAAS
>Mature_411_residues
TILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWITDVDGRRYLDCLSAYSAVNFGHRHPEIVATAHAQLDTV
TLVSRAVHSDKLGPFCAALAYLCDKDMVLPMNSGAEAVESGLKVARKWGAEVKGVPAGQANIIVADNNFHGRTISIVSFS
SDAAARDGFGPFTPGFRSVPFGDAGTLAQAIDDNTVAVLLEPIQGEAGIVVPPDDYLPAVRALCSEHNVLMIADEIQSGL
ARTGYTFACDRWRVVPDVYLLGKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPLAAAIGTTVVSMLARGEYQARA
TALGAHLQRRLRALVGHGVDEVRGLGLWAGVDIDPSLGSGREMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEIDWAVG
QLAAVLREAAS

Specific function: Catalyzes the interconversion of ornithine to glutamate semialdehyde [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=385, Percent_Identity=46.4935064935065, Blast_Score=343, Evalue=1e-94,
Organism=Homo sapiens, GI284507298, Length=287, Percent_Identity=47.7351916376307, Blast_Score=257, Evalue=1e-68,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=26.9047619047619, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=27.4698795180723, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=26.1904761904762, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI13994255, Length=436, Percent_Identity=25.2293577981651, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=26.2210796915167, Blast_Score=118, Evalue=8e-27,
Organism=Escherichia coli, GI145693181, Length=374, Percent_Identity=35.2941176470588, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789759, Length=385, Percent_Identity=35.0649350649351, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1788044, Length=389, Percent_Identity=33.1619537275064, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI1787560, Length=408, Percent_Identity=32.3529411764706, Blast_Score=175, Evalue=5e-45,
Organism=Escherichia coli, GI1789016, Length=412, Percent_Identity=26.6990291262136, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786991, Length=408, Percent_Identity=29.1666666666667, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1786349, Length=298, Percent_Identity=28.5234899328859, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=380, Percent_Identity=42.6315789473684, Blast_Score=335, Evalue=3e-92,
Organism=Caenorhabditis elegans, GI25144274, Length=262, Percent_Identity=41.6030534351145, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI71981843, Length=167, Percent_Identity=44.311377245509, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=24.6013667425968, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71992977, Length=421, Percent_Identity=27.790973871734, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17541228, Length=424, Percent_Identity=25.9433962264151, Blast_Score=95, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6323470, Length=410, Percent_Identity=43.1707317073171, Blast_Score=333, Evalue=3e-92,
Organism=Saccharomyces cerevisiae, GI6324432, Length=370, Percent_Identity=28.9189189189189, Blast_Score=161, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6324386, Length=465, Percent_Identity=24.9462365591398, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI21357415, Length=376, Percent_Identity=47.3404255319149, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI28574759, Length=466, Percent_Identity=27.8969957081545, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI161085790, Length=465, Percent_Identity=27.3118279569892, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21356575, Length=365, Percent_Identity=27.9452054794521, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR010164
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.13 [H]

Molecular weight: Translated: 43270; Mature: 43139

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWITDVDGRRYLDCLSAYSA
CEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHH
VNFGHRHPEIVATAHAQLDTVTLVSRAVHSDKLGPFCAALAYLCDKDMVLPMNSGAEAVE
HCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCHHHHH
SGLKVARKWGAEVKGVPAGQANIIVADNNFHGRTISIVSFSSDAAARDGFGPFTPGFRSV
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
PFGDAGTLAQAIDDNTVAVLLEPIQGEAGIVVPPDDYLPAVRALCSEHNVLMIADEIQSG
CCCCCHHHHHHHCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHCCCCEEEEHHHHHHH
LARTGYTFACDRWRVVPDVYLLGKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPL
HHHCCCEEEECCEEECCHHHHHHHHHCCCCCHHHHHHHCHHHEEEECCCCCCCCCCCCHH
AAAIGTTVVSMLARGEYQARATALGAHLQRRLRALVGHGVDEVRGLGLWAGVDIDPSLGS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCCCC
GREMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEIDWAVGQLAAVLREAAS
CCCEEEEHHHCCEEEEECCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TILDGQLTATRVDSAIRLAEKRAAHNYSPLPIVAASAQGAWITDVDGRRYLDCLSAYSA
EEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEECCCCHHHHHHHHHHHH
VNFGHRHPEIVATAHAQLDTVTLVSRAVHSDKLGPFCAALAYLCDKDMVLPMNSGAEAVE
HCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCCCHHHHH
SGLKVARKWGAEVKGVPAGQANIIVADNNFHGRTISIVSFSSDAAARDGFGPFTPGFRSV
HHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
PFGDAGTLAQAIDDNTVAVLLEPIQGEAGIVVPPDDYLPAVRALCSEHNVLMIADEIQSG
CCCCCHHHHHHHCCCEEEEEEEECCCCCCEEECCCHHHHHHHHHHCCCCEEEEHHHHHHH
LARTGYTFACDRWRVVPDVYLLGKALGGGVVPLSAVVADREILGVLHPGEHGSTFGGNPL
HHHCCCEEEECCEEECCHHHHHHHHHCCCCCHHHHHHHCHHHEEEECCCCCCCCCCCCHH
AAAIGTTVVSMLARGEYQARATALGAHLQRRLRALVGHGVDEVRGLGLWAGVDIDPSLGS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCEEEECCCCCCCCCC
GREMSLRLAERGVLVKDTHGATLRFAPPLVVTAQEIDWAVGQLAAVLREAAS
CCCEEEEHHHCCEEEEECCCCEEEECCCEEEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA