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The map label for this gene is htpG

Identifier: 41408167

GI number: 41408167

Start: 2276782

End: 2278716

Strand: Reverse

Name: htpG

Synonym: MAP2069c

Alternate gene names: 41408167

Gene position: 2278716-2276782 (Counterclockwise)

Preceding gene: 41408169

Following gene: 41408166

Centisome position: 47.18

GC content: 64.39

Gene sequence:

>1935_bases
ATGAACGCGCGCGTCGAGCAGTTGGAGTTTCAAGCCGAGGCTCGGCAACTGCTGGATCTGATGGTCCACTCCGTCTACTC
CAACAAGGACTCGTTCCTGCGGGAGTTGATCTCGAACGCTTCCGACGCACTGGACAAGCTGCGGCTGGAAGCCTTCCGCA
ACAAGGACCTCGACGTCGACACCTCCGACCTGCACATCCAGATCGAGGTGGACAAGGATGCGCGCACCCTGACCATCCGC
GACAACGGCATCGGCATGACCCGCGCCGAGGTGGTCGACCTGATCGGCACCCTGGCCAAGTCGGGCACCGCCGAATTGCG
CCAACAACTCCGGGAAGCCAAGAACGCCCAGAACGAAGCCGCCTCAGAGGAACTCATCGGCCAGTTCGGCATCGGCTTCT
ACTCCAGCTTCATGGTGGCCGACAAGGTCGAACTGCTCACCCGCAAGGCCGGCGAGAGCGAGGCCACCAAATGGGAGTCG
AGCGGCGAGGGCACCTACACCATCGAATCGGTCGAGAACGCCCCGCAGGGAACCTCGGTCACCCTGCATCTGAAGCCCGA
GGACACCGAGGACGAGCTGCACGACTACACCTCGGAGTTCAAGATCAAGAGCCTGGTCAAGAAGTACTCCGACTTCATCG
CCTGGCCCATCCGGATGGAGGTGGAGCGGCGCACGCCCGCCACCGAAGAGGGCGGCGAGGAGACCGTCACCCGGGAGGTC
GAGACCCTCAACTCGATGAAGGCCCTGTGGGCCCGGCCCAAGGACGAGGTCTCCGAGGAGGAGTACAAGGAGTTCTACAA
GCACATCGCGCACGCCTGGGACGACCCGCTCGAGGTCATCGCGATGAAGGCCGAGGGCACCTTCGAGTACCAGGCGCTGC
TGTTCATCCCGTCCCACGCCCCGTTCGACCTGTTCAACCGGGACGCGCACACCGGCATCCAGCTCTACGTCAAGCGGGTG
TTCATCATGGGTGACTGCGACCAGCTGATGCCCGAATACCTGCGCTTCGTCAAGGGTGTCGTTGACGCACAGGACATGTC
GCTCAACGTGTCCCGCGAGATCCTGCAACAGGACCGGCAGATCAAGGCCATCCGGCGGCGGCTGACCAAGAAGGTTCTGT
CCACCATCAAGGAGTTGCAATCCGAGCGGCTCGACGACTACCGGACCTTCTGGACTCAGTTCGGCCGGGTGGTCAAGGAG
GGTCTGCTGTCGGACTTCGACAACCAGGAGACGCTGGTGCAGCTCTGCTCCTTCGCCTCGACGCACAGCGAGGAGGAGGC
CACCACGCTGGCCCAGTACGTCGAGCGGATGAAGGAAGGGCAGACGCAGATCTTCTACGCCACCGGCGAAACGCGCCAGC
AGATCCTCAAGTCGCCGCATCTGGAGGCGTTCAAGGCCAAGGGCTACGAGGTGCTGCTGCTCACCGACCCGGTCGACGAG
GTCTGGGTGGGAACCGTCACCGAGTTCGACGGCAAGCCGCTGCAGTCAATCGCCAAGGGCGAGGTGGACCTGAGCGCCGA
GGGCGAGGAGAGCCAGGCCGAGCGGGATGAGCAGCAGAAGGAATTCGCCGATCTGCTCGCCTGGCTGAAGGACACCCTGT
CCGACCACGTCAAGGAGGTCCGGCTGTCCAACCGACTGACCGACTCGCCGGCCTGCCTGATCACCGACGCCTTCGGCATC
ACACCGGCGCTGGCCCGGCTCTACCGCGCCTCCGGGCAGGACATTCCGGTGGGCAAGCGAATACTGGAACTCAATCCCAA
GCACCCACTGGTCACCGGCCTGCGCCAAGCCCACCAGGACCGCGCCGACGATCCGTCCGTCGCCGAGACCGCGGAATTGC
TTTACGGCACAGCGCTTCTGGCCGAGGGCGGCGCCCTCGACGACCCGGCCCGGTTCGCCGAGATACTGGCCGACCGGTTG
GCCCGCACCCTGTAG

Upstream 100 bases:

>100_bases
GTCGAGCAACAGACATGGGTTCAGCGTAGGGCCAGCCCCCGGGCGGCGACCATCGATTACTCGGTAAATTTGAAACGTCA
AGTTGTCGAAGGGGAATGCC

Downstream 100 bases:

>100_bases
CCCCGGGCCGCCGCAGCAAATCGGCGAATTCGGGGATTGAAAAGCGCCGGGCAGGGATACTTAAGTCCCATGGCCGAGTT
CCGCGTGATCGACCCGCACG

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 644; Mature: 644

Protein sequence:

>644_residues
MNARVEQLEFQAEARQLLDLMVHSVYSNKDSFLRELISNASDALDKLRLEAFRNKDLDVDTSDLHIQIEVDKDARTLTIR
DNGIGMTRAEVVDLIGTLAKSGTAELRQQLREAKNAQNEAASEELIGQFGIGFYSSFMVADKVELLTRKAGESEATKWES
SGEGTYTIESVENAPQGTSVTLHLKPEDTEDELHDYTSEFKIKSLVKKYSDFIAWPIRMEVERRTPATEEGGEETVTREV
ETLNSMKALWARPKDEVSEEEYKEFYKHIAHAWDDPLEVIAMKAEGTFEYQALLFIPSHAPFDLFNRDAHTGIQLYVKRV
FIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKELQSERLDDYRTFWTQFGRVVKE
GLLSDFDNQETLVQLCSFASTHSEEEATTLAQYVERMKEGQTQIFYATGETRQQILKSPHLEAFKAKGYEVLLLTDPVDE
VWVGTVTEFDGKPLQSIAKGEVDLSAEGEESQAERDEQQKEFADLLAWLKDTLSDHVKEVRLSNRLTDSPACLITDAFGI
TPALARLYRASGQDIPVGKRILELNPKHPLVTGLRQAHQDRADDPSVAETAELLYGTALLAEGGALDDPARFAEILADRL
ARTL

Sequences:

>Translated_644_residues
MNARVEQLEFQAEARQLLDLMVHSVYSNKDSFLRELISNASDALDKLRLEAFRNKDLDVDTSDLHIQIEVDKDARTLTIR
DNGIGMTRAEVVDLIGTLAKSGTAELRQQLREAKNAQNEAASEELIGQFGIGFYSSFMVADKVELLTRKAGESEATKWES
SGEGTYTIESVENAPQGTSVTLHLKPEDTEDELHDYTSEFKIKSLVKKYSDFIAWPIRMEVERRTPATEEGGEETVTREV
ETLNSMKALWARPKDEVSEEEYKEFYKHIAHAWDDPLEVIAMKAEGTFEYQALLFIPSHAPFDLFNRDAHTGIQLYVKRV
FIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKELQSERLDDYRTFWTQFGRVVKE
GLLSDFDNQETLVQLCSFASTHSEEEATTLAQYVERMKEGQTQIFYATGETRQQILKSPHLEAFKAKGYEVLLLTDPVDE
VWVGTVTEFDGKPLQSIAKGEVDLSAEGEESQAERDEQQKEFADLLAWLKDTLSDHVKEVRLSNRLTDSPACLITDAFGI
TPALARLYRASGQDIPVGKRILELNPKHPLVTGLRQAHQDRADDPSVAETAELLYGTALLAEGGALDDPARFAEILADRL
ARTL
>Mature_644_residues
MNARVEQLEFQAEARQLLDLMVHSVYSNKDSFLRELISNASDALDKLRLEAFRNKDLDVDTSDLHIQIEVDKDARTLTIR
DNGIGMTRAEVVDLIGTLAKSGTAELRQQLREAKNAQNEAASEELIGQFGIGFYSSFMVADKVELLTRKAGESEATKWES
SGEGTYTIESVENAPQGTSVTLHLKPEDTEDELHDYTSEFKIKSLVKKYSDFIAWPIRMEVERRTPATEEGGEETVTREV
ETLNSMKALWARPKDEVSEEEYKEFYKHIAHAWDDPLEVIAMKAEGTFEYQALLFIPSHAPFDLFNRDAHTGIQLYVKRV
FIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQIKAIRRRLTKKVLSTIKELQSERLDDYRTFWTQFGRVVKE
GLLSDFDNQETLVQLCSFASTHSEEEATTLAQYVERMKEGQTQIFYATGETRQQILKSPHLEAFKAKGYEVLLLTDPVDE
VWVGTVTEFDGKPLQSIAKGEVDLSAEGEESQAERDEQQKEFADLLAWLKDTLSDHVKEVRLSNRLTDSPACLITDAFGI
TPALARLYRASGQDIPVGKRILELNPKHPLVTGLRQAHQDRADDPSVAETAELLYGTALLAEGGALDDPARFAEILADRL
ARTL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=690, Percent_Identity=38.5507246376812, Blast_Score=456, Evalue=1e-128,
Organism=Homo sapiens, GI20149594, Length=672, Percent_Identity=38.6904761904762, Blast_Score=451, Evalue=1e-126,
Organism=Homo sapiens, GI155722983, Length=656, Percent_Identity=31.859756097561, Blast_Score=332, Evalue=8e-91,
Organism=Homo sapiens, GI154146191, Length=411, Percent_Identity=39.6593673965937, Blast_Score=309, Evalue=5e-84,
Organism=Homo sapiens, GI153792590, Length=411, Percent_Identity=39.6593673965937, Blast_Score=305, Evalue=6e-83,
Organism=Escherichia coli, GI1786679, Length=627, Percent_Identity=48.4848484848485, Blast_Score=571, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17559162, Length=673, Percent_Identity=40.1188707280832, Blast_Score=470, Evalue=1e-133,
Organism=Caenorhabditis elegans, GI17542208, Length=681, Percent_Identity=35.8296622613803, Blast_Score=417, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115535205, Length=660, Percent_Identity=32.7272727272727, Blast_Score=319, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI115535167, Length=451, Percent_Identity=34.1463414634146, Blast_Score=250, Evalue=2e-66,
Organism=Saccharomyces cerevisiae, GI6323840, Length=675, Percent_Identity=39.2592592592593, Blast_Score=460, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6325016, Length=679, Percent_Identity=38.880706921944, Blast_Score=460, Evalue=1e-130,
Organism=Drosophila melanogaster, GI17647529, Length=696, Percent_Identity=38.2183908045977, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI21357739, Length=688, Percent_Identity=36.046511627907, Blast_Score=404, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24586016, Length=661, Percent_Identity=32.9803328290469, Blast_Score=353, Evalue=2e-97,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 72829; Mature: 72829

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNARVEQLEFQAEARQLLDLMVHSVYSNKDSFLRELISNASDALDKLRLEAFRNKDLDVD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TSDLHIQIEVDKDARTLTIRDNGIGMTRAEVVDLIGTLAKSGTAELRQQLREAKNAQNEA
CCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
ASEELIGQFGIGFYSSFMVADKVELLTRKAGESEATKWESSGEGTYTIESVENAPQGTSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEECCCCCCCCCEE
TLHLKPEDTEDELHDYTSEFKIKSLVKKYSDFIAWPIRMEVERRTPATEEGGEETVTREV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHH
ETLNSMKALWARPKDEVSEEEYKEFYKHIAHAWDDPLEVIAMKAEGTFEYQALLFIPSHA
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCEEEEEEEEECCCC
PFDLFNRDAHTGIQLYVKRVFIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQ
CHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHH
IKAIRRRLTKKVLSTIKELQSERLDDYRTFWTQFGRVVKEGLLSDFDNQETLVQLCSFAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
THSEEEATTLAQYVERMKEGQTQIFYATGETRQQILKSPHLEAFKAKGYEVLLLTDPVDE
CCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCHHHHHCCCEEEEEEECCCHH
VWVGTVTEFDGKPLQSIAKGEVDLSAEGEESQAERDEQQKEFADLLAWLKDTLSDHVKEV
HHCCCHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSNRLTDSPACLITDAFGITPALARLYRASGQDIPVGKRILELNPKHPLVTGLRQAHQD
HHHHCCCCCCCEEEECHHCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHC
RADDPSVAETAELLYGTALLAEGGALDDPARFAEILADRLARTL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNARVEQLEFQAEARQLLDLMVHSVYSNKDSFLRELISNASDALDKLRLEAFRNKDLDVD
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TSDLHIQIEVDKDARTLTIRDNGIGMTRAEVVDLIGTLAKSGTAELRQQLREAKNAQNEA
CCCEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHH
ASEELIGQFGIGFYSSFMVADKVELLTRKAGESEATKWESSGEGTYTIESVENAPQGTSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCEEEECCCCCCCCCEE
TLHLKPEDTEDELHDYTSEFKIKSLVKKYSDFIAWPIRMEVERRTPATEEGGEETVTREV
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHH
ETLNSMKALWARPKDEVSEEEYKEFYKHIAHAWDDPLEVIAMKAEGTFEYQALLFIPSHA
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHCCCCHHEEEEECCCCEEEEEEEEECCCC
PFDLFNRDAHTGIQLYVKRVFIMGDCDQLMPEYLRFVKGVVDAQDMSLNVSREILQQDRQ
CHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHH
IKAIRRRLTKKVLSTIKELQSERLDDYRTFWTQFGRVVKEGLLSDFDNQETLVQLCSFAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
THSEEEATTLAQYVERMKEGQTQIFYATGETRQQILKSPHLEAFKAKGYEVLLLTDPVDE
CCCHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCHHHHHCCCEEEEEEECCCHH
VWVGTVTEFDGKPLQSIAKGEVDLSAEGEESQAERDEQQKEFADLLAWLKDTLSDHVKEV
HHCCCHHCCCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSNRLTDSPACLITDAFGITPALARLYRASGQDIPVGKRILELNPKHPLVTGLRQAHQD
HHHHCCCCCCCEEEECHHCCCHHHHHHHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHC
RADDPSVAETAELLYGTALLAEGGALDDPARFAEILADRLARTL
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA