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The map label for this gene is kasB_1

Identifier: 41408097

GI number: 41408097

Start: 2205243

End: 2206565

Strand: Direct

Name: kasB_1

Synonym: MAP1999

Alternate gene names: 41408097

Gene position: 2205243-2206565 (Clockwise)

Preceding gene: 41408096

Following gene: 41408098

Centisome position: 45.66

GC content: 67.42

Gene sequence:

>1323_bases
ATGCGGGCCGCACCGGCCCGCAAAGTTGCCGGACAAGTTAGGGAAGGAATCTTCGCAAGACCCATGACAGAGCTGGTTAC
CGGGAAAACGCTCCCGAACGTGGTCGTCACCGGCATCGCCATGACGACCGCGCTGGCGACTGACGCCGAGACCACCTGGA
AGCTGTTGCTGGACAGTCAAAGTGGTATCCGCACACTCGACGATCCCTTCGTCGAGGAGTTCGACCTGCCGGTGCGCATC
GGCGGACATCTGTTGGAGGAGTTCGACAGTCAGCTGACCCGCGTCGAGCTGCGCCGGACGGGCTACCTGCAACGGATGTC
CACCATCTTGGGCCGGCGGGTCTGGGAGAACGCCGGCTCGCCCGAGGTGGACAGCAACCGGCTGATGGTCTCCATCGGTA
CCGGCCTGGGGTCATCCGAGGAAATGGTCTTCAGCTACGACGACATGCGCGCGCGAGGCATGAAGGCGGTCTCCCCGCTC
GGTGTGCAGAAGTACATGCCCAATGGCGCAGCCGCGGCGGTCGGGCTGGAACACCACGCCAAGGCCGGCGTCATCACCCC
GGTCTCGGCGTGCGCGTCGGGCTCCGAGGGCATCGCCCAGGCGTGGCGCAACATCGTCTTCGGCGAGGCCGACATCGCGA
TCTGCGGCGGTGTCGAGACGAAGATCGAGGCGGTGCCGATCGCGGCGTTCGCCCAGATGCGCATCGTGATGTCGACCAAG
AACGACGACCCTGTCGGCGCCTGTCGCCCGTTCGACCGGGACCGCACCGGCTTCGTGTTCGGCGAGGCCGGCGCGCTGAT
GGTGATCGAAACCGAGGAACACGCCAAGGCCCGCGGCGCCAACATCCTGGCCCGCATCATGGGCGCCAGCATCACCTCCG
ACGGCTACCACATGGTCGCCCCGGACCCCAACGGCGAACGCGCCGGACACGCCATGAGCCGCGCCATCCAGCTGGCCGGC
CTGACGCCCGGCGACATCGATCACGTCAACGCGCACGCCACCGGCACCTCGGTGGGCGACGTGGCCGAGAGCAAGGCCAT
CAACAACGCGCTGGGCCCGCACGGCGGCAACGCCGCCGTCTACGCCCCAAAGGCCGCGCTCGGCCACTCGGTGGGCGCGG
TCGGCGCGGTCGAGTCCATCCTGACCGTGCTGGCCCTGCGCGACCAGGTCGTCCCGCCCACCCTGAACCTGGAAAACCTC
GACCCCGAAATCGATTTGGACGTGGTGGCGGGCAAACCGCGACCGGGCAACTACCAGTACGCGATCAACAACTCGTTCGG
CTTCGGCGGCCACAACGTCGCCATCGCCTTCGGACGGTACTGA

Upstream 100 bases:

>100_bases
CTACGGCGACTACCAATACGCGATCAACAACTCGTTCGGCTTCGGTGGCCACAACGTGGCACTGGCCTTCGGGCGCTACT
GAGCACGACGTCCGGCGACG

Downstream 100 bases:

>100_bases
ACCCACGGTCCCGAGCAGCACCGGAATACAGGAGACCCTGCGATGACTATCACGGCCCCCGAGACGGTTGGCGAGTCGCT
CGACCCCCGCGACCCGCTGT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: Beta-ketoacyl-ACP synthase 2; KAS 2 [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MRAAPARKVAGQVREGIFARPMTELVTGKTLPNVVVTGIAMTTALATDAETTWKLLLDSQSGIRTLDDPFVEEFDLPVRI
GGHLLEEFDSQLTRVELRRTGYLQRMSTILGRRVWENAGSPEVDSNRLMVSIGTGLGSSEEMVFSYDDMRARGMKAVSPL
GVQKYMPNGAAAAVGLEHHAKAGVITPVSACASGSEGIAQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTK
NDDPVGACRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHMVAPDPNGERAGHAMSRAIQLAG
LTPGDIDHVNAHATGTSVGDVAESKAINNALGPHGGNAAVYAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLENL
DPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY

Sequences:

>Translated_440_residues
MRAAPARKVAGQVREGIFARPMTELVTGKTLPNVVVTGIAMTTALATDAETTWKLLLDSQSGIRTLDDPFVEEFDLPVRI
GGHLLEEFDSQLTRVELRRTGYLQRMSTILGRRVWENAGSPEVDSNRLMVSIGTGLGSSEEMVFSYDDMRARGMKAVSPL
GVQKYMPNGAAAAVGLEHHAKAGVITPVSACASGSEGIAQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTK
NDDPVGACRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHMVAPDPNGERAGHAMSRAIQLAG
LTPGDIDHVNAHATGTSVGDVAESKAINNALGPHGGNAAVYAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLENL
DPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY
>Mature_440_residues
MRAAPARKVAGQVREGIFARPMTELVTGKTLPNVVVTGIAMTTALATDAETTWKLLLDSQSGIRTLDDPFVEEFDLPVRI
GGHLLEEFDSQLTRVELRRTGYLQRMSTILGRRVWENAGSPEVDSNRLMVSIGTGLGSSEEMVFSYDDMRARGMKAVSPL
GVQKYMPNGAAAAVGLEHHAKAGVITPVSACASGSEGIAQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTK
NDDPVGACRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHMVAPDPNGERAGHAMSRAIQLAG
LTPGDIDHVNAHATGTSVGDVAESKAINNALGPHGGNAAVYAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLENL
DPEIDLDVVAGKPRPGNYQYAINNSFGFGGHNVAIAFGRY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=417, Percent_Identity=33.8129496402878, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI223972627, Length=237, Percent_Identity=34.5991561181435, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI41872631, Length=254, Percent_Identity=29.1338582677165, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI1787337, Length=414, Percent_Identity=36.231884057971, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1788663, Length=410, Percent_Identity=32.6829268292683, Blast_Score=167, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI71983541, Length=330, Percent_Identity=35.7575757575758, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI71983535, Length=265, Percent_Identity=38.4905660377359, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI212642053, Length=381, Percent_Identity=26.246719160105, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17550940, Length=289, Percent_Identity=26.643598615917, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=447, Percent_Identity=31.9910514541387, Blast_Score=212, Evalue=9e-56,
Organism=Drosophila melanogaster, GI24644341, Length=441, Percent_Identity=33.7868480725624, Blast_Score=237, Evalue=1e-62,
Organism=Drosophila melanogaster, GI221330659, Length=387, Percent_Identity=24.2894056847545, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19920632, Length=387, Percent_Identity=24.2894056847545, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581345, Length=258, Percent_Identity=24.4186046511628, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 46407; Mature: 46407

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAAPARKVAGQVREGIFARPMTELVTGKTLPNVVVTGIAMTTALATDAETTWKLLLDSQ
CCCCCHHHHHHHHHHCHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
SGIRTLDDPFVEEFDLPVRIGGHLLEEFDSQLTRVELRRTGYLQRMSTILGRRVWENAGS
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEVDSNRLMVSIGTGLGSSEEMVFSYDDMRARGMKAVSPLGVQKYMPNGAAAAVGLEHHA
CCCCCCEEEEEEECCCCCCCCEEEEECCHHHCCCCCCCCCCHHHHCCCCCCEEECHHHHC
KAGVITPVSACASGSEGIAQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTK
CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEHHHHHEEEEEEECC
NDDPVGACRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHMVA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
PDPNGERAGHAMSRAIQLAGLTPGDIDHVNAHATGTSVGDVAESKAINNALGPHGGNAAV
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
YAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLENLDPEIDLDVVAGKPRPGNYQY
EECHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEE
AINNSFGFGGHNVAIAFGRY
EECCCCCCCCCEEEEEECCC
>Mature Secondary Structure
MRAAPARKVAGQVREGIFARPMTELVTGKTLPNVVVTGIAMTTALATDAETTWKLLLDSQ
CCCCCHHHHHHHHHHCHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECC
SGIRTLDDPFVEEFDLPVRIGGHLLEEFDSQLTRVELRRTGYLQRMSTILGRRVWENAGS
CCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PEVDSNRLMVSIGTGLGSSEEMVFSYDDMRARGMKAVSPLGVQKYMPNGAAAAVGLEHHA
CCCCCCEEEEEEECCCCCCCCEEEEECCHHHCCCCCCCCCCHHHHCCCCCCEEECHHHHC
KAGVITPVSACASGSEGIAQAWRNIVFGEADIAICGGVETKIEAVPIAAFAQMRIVMSTK
CCCCCCHHHHHCCCCHHHHHHHHHHCCCCCCEEEECCCCCEEEEEEHHHHHEEEEEEECC
NDDPVGACRPFDRDRTGFVFGEAGALMVIETEEHAKARGANILARIMGASITSDGYHMVA
CCCCCCCCCCCCCCCCEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCCCCCCCEEEC
PDPNGERAGHAMSRAIQLAGLTPGDIDHVNAHATGTSVGDVAESKAINNALGPHGGNAAV
CCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEE
YAPKAALGHSVGAVGAVESILTVLALRDQVVPPTLNLENLDPEIDLDVVAGKPRPGNYQY
EECHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCEEE
AINNSFGFGGHNVAIAFGRY
EECCCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]