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The map label for this gene is dmpD [H]

Identifier: 41406798

GI number: 41406798

Start: 722440

End: 723261

Strand: Direct

Name: dmpD [H]

Synonym: MAP0700

Alternate gene names: 41406798

Gene position: 722440-723261 (Clockwise)

Preceding gene: 41406797

Following gene: 41406800

Centisome position: 14.96

GC content: 68.86

Gene sequence:

>822_bases
ATGGAGATTCATCGCAAAACGATGTCGGTCGATGGCCTGGTCACCAGCTACCTTGAGGCGGGCGAGGGCGACCCGGTGGT
GTTGCTGCACGGCGGGGAGTTCGGGGCCAGCGCCGAGCTCGGCTGGGAACGCAACATCGCCGCACTCGCCGCGCGCTACC
GGGTGTTGGCGCCCGACCAGTTGGGCTTCGGCGGGTCGGCCAAGGTCATCGACTTCGTCGACGGTCGCGGCATGCGGATC
CGGCACGTGGCCCGGTTCTGCGAACTGCTCGGCGTCGAGTCGGCGCACTTCGTCGGCAATTCGATGGGCGCCATCAATCT
GCTCACCGACGCCACGTCGGACAGCCCGCTGTGGCCGGTCCGCAGCGCCGTGATCATCTGCGGCGGCGGCGAAATCCAGC
AGAACGAGCATTTCGAGGCGCTGCAGAACTACGACGCCACGCTGCCCGCGATGCGCCGCATCGTCGAAGCGCTGTTCTTC
GACCCGGCCTATCCCGCCGACGACGACTACGTGCGCCGCCGGCACGAGTCCAGCACCGCGCCGGGGGCGTGGGAGGCCAT
CGCCGCGGCCAGGTTCCGGCGGCCGGGTGCCACGCCGTCCCCGACGCCGTCGAGCGCCCGGGCCTACGAACGCATTGGTG
TGCCAACGCTTGTCGTGGAGGGCGGAGGCGACAAACTCCTTCCCGCCGGCTGGTCGGCTCAGATCGCCAAGCAGATCGAC
GGCGCGCGCTCGGTCGTGGTGGACGATGCCGGGCACTGTCCGCAGATCGAGCAGCCGTCCGTGGTCAACCAGTTGCTGAT
GGATTTTCTGGCGACCGCCTGA

Upstream 100 bases:

>100_bases
CGGCGTCTACGAATTCCAGCTTGTCGCACCGCCGTTGAGGTTTGTGGGGGCAGTGGGTTCGCCGGTGAACCCGATCGCGA
TCAAATAGAGAAGGCGGGCG

Downstream 100 bases:

>100_bases
GCGTAACCAGGCGGCGTCACAGGCAGCGTCACAGAACGTAGTCCAGCCGGGTCTCCATTCCGGCGACCTGGTGATAGGTG
TTGTGGCAGTGCATCACCCA

Product: hypothetical protein

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: HMSH [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MEIHRKTMSVDGLVTSYLEAGEGDPVVLLHGGEFGASAELGWERNIAALAARYRVLAPDQLGFGGSAKVIDFVDGRGMRI
RHVARFCELLGVESAHFVGNSMGAINLLTDATSDSPLWPVRSAVIICGGGEIQQNEHFEALQNYDATLPAMRRIVEALFF
DPAYPADDDYVRRRHESSTAPGAWEAIAAARFRRPGATPSPTPSSARAYERIGVPTLVVEGGGDKLLPAGWSAQIAKQID
GARSVVVDDAGHCPQIEQPSVVNQLLMDFLATA

Sequences:

>Translated_273_residues
MEIHRKTMSVDGLVTSYLEAGEGDPVVLLHGGEFGASAELGWERNIAALAARYRVLAPDQLGFGGSAKVIDFVDGRGMRI
RHVARFCELLGVESAHFVGNSMGAINLLTDATSDSPLWPVRSAVIICGGGEIQQNEHFEALQNYDATLPAMRRIVEALFF
DPAYPADDDYVRRRHESSTAPGAWEAIAAARFRRPGATPSPTPSSARAYERIGVPTLVVEGGGDKLLPAGWSAQIAKQID
GARSVVVDDAGHCPQIEQPSVVNQLLMDFLATA
>Mature_273_residues
MEIHRKTMSVDGLVTSYLEAGEGDPVVLLHGGEFGASAELGWERNIAALAARYRVLAPDQLGFGGSAKVIDFVDGRGMRI
RHVARFCELLGVESAHFVGNSMGAINLLTDATSDSPLWPVRSAVIICGGGEIQQNEHFEALQNYDATLPAMRRIVEALFF
DPAYPADDDYVRRRHESSTAPGAWEAIAAARFRRPGATPSPTPSSARAYERIGVPTLVVEGGGDKLLPAGWSAQIAKQID
GARSVVVDDAGHCPQIEQPSVVNQLLMDFLATA

Specific function: Conversion of 2-hydroxymuconic acid semialdehyde to 2- hydroxypent-2,4-dienoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Escherichia coli, GI87081721, Length=271, Percent_Identity=25.830258302583, Blast_Score=76, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 29295; Mature: 29295

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIHRKTMSVDGLVTSYLEAGEGDPVVLLHGGEFGASAELGWERNIAALAARYRVLAPDQ
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHEECCCC
LGFGGSAKVIDFVDGRGMRIRHVARFCELLGVESAHFVGNSMGAINLLTDATSDSPLWPV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCCCCCC
RSAVIICGGGEIQQNEHFEALQNYDATLPAMRRIVEALFFDPAYPADDDYVRRRHESSTA
CEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
PGAWEAIAAARFRRPGATPSPTPSSARAYERIGVPTLVVEGGGDKLLPAGWSAQIAKQID
CCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCEECCCCCHHHHHHHHC
GARSVVVDDAGHCPQIEQPSVVNQLLMDFLATA
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEIHRKTMSVDGLVTSYLEAGEGDPVVLLHGGEFGASAELGWERNIAALAARYRVLAPDQ
CCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHEECCCC
LGFGGSAKVIDFVDGRGMRIRHVARFCELLGVESAHFVGNSMGAINLLTDATSDSPLWPV
CCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCCCCCCCCC
RSAVIICGGGEIQQNEHFEALQNYDATLPAMRRIVEALFFDPAYPADDDYVRRRHESSTA
CEEEEEECCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCC
PGAWEAIAAARFRRPGATPSPTPSSARAYERIGVPTLVVEGGGDKLLPAGWSAQIAKQID
CCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCEEEEECCCCEECCCCCHHHHHHHHC
GARSVVVDDAGHCPQIEQPSVVNQLLMDFLATA
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2194577 [H]