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The map label for this gene is mer [H]

Identifier: 41406773

GI number: 41406773

Start: 696359

End: 697315

Strand: Direct

Name: mer [H]

Synonym: MAP0675

Alternate gene names: 41406773

Gene position: 696359-697315 (Clockwise)

Preceding gene: 41406772

Following gene: 41406774

Centisome position: 14.42

GC content: 69.8

Gene sequence:

>957_bases
GTGCGCGTCGGAGTGATGATCGGCGCCGAGCGCGGCGACATGGCCCGCAAGGTGAACAAGCTGGTCTCCGACATCGAATG
GGCCGAGTCGGCGGGACTGGACACGGCGTGGATGCCGCAGGTGCCCAACGACTTCGACTGCCTGACCATGGTGTCGCTGA
TGGCCGCGCACAGCTCCCGCATCGAGCTGGGCACCGCGGTGGTGCCGTTGCAGGCCCAGCATCCGATCGCCCTTGCCCGT
CAAGCGCTTTCGACGCACGCGGTGGCCGGTGGCCGGCTGGCGCTGGGTGTCGGGCCGTCGCACCACTGGATCATCCGGGA
CATGCTCGGCCTGCCGTACCAGAAACCGGCCGCCTACACCCGCGACTACCTGCAGGTGCTCAACGCCGCTATCGCCGGGC
CGGGACCGGTTGACGTCGAGAACGATTCGTTCACCGTCCACAATCCCATGGTGATCGGGGCCGACACCCCGATGCCGGTA
CTGGTGGCCGCGCTGGGGCCCGTGATGCTGCAGATCGCCGGTGAACTCGCCGACGGCACCGTGCTGTGGATGGCCGACGA
GCGCGCGATCGGCGAGCACATCGCGCCGAAGATCACCAAGGCCGCCGCCGACGCCGGCCGCCCCGCGCCGCGGATCGTTG
CCGGCATCCCGGTATGCCTGTGCGCGCCAAGCCAGGTCGACGAGGCCAAGGAGCGGGCCAACCGCATTCTGGGCGAGGCC
GAGGTGTCGCCCAACTACCAGCGGCTGCTCGAACGCGGCGACGCCCGCGACGTCGGCGACCTGTGCGCGGCCGGCGAACC
CGAACAGATTCTGGCCCGGATGCGACGCTTCGCCGACGCCGGCGTCACGGATCTGTCGGTGCGGCTGCTGCCCATCGGCG
ACAACCGCGACGAGCTGGTGGCCTCCAAGAGCCGGACCCGCGAGATGATCGCCTCACTTGCCGCGGAGTTACGTTGA

Upstream 100 bases:

>100_bases
TATTCCCCACCGGCACGCCGCTGGACAAACTGGTGCGTGAGATCCGCGCACTGACCGGCACCGGGGAGCCGGACGACAAG
GAAGCGATCACGGAGGAACA

Downstream 100 bases:

>100_bases
GCGGCAACAACACCGGGCCGTTGGCGGGGATCCGTATCCTCGAGGTCGGCACCATGCTGGCGGGCCCGTACTCCACCATG
CTGCTCGCCGATCTCGGCGC

Product: hypothetical protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MRVGVMIGAERGDMARKVNKLVSDIEWAESAGLDTAWMPQVPNDFDCLTMVSLMAAHSSRIELGTAVVPLQAQHPIALAR
QALSTHAVAGGRLALGVGPSHHWIIRDMLGLPYQKPAAYTRDYLQVLNAAIAGPGPVDVENDSFTVHNPMVIGADTPMPV
LVAALGPVMLQIAGELADGTVLWMADERAIGEHIAPKITKAAADAGRPAPRIVAGIPVCLCAPSQVDEAKERANRILGEA
EVSPNYQRLLERGDARDVGDLCAAGEPEQILARMRRFADAGVTDLSVRLLPIGDNRDELVASKSRTREMIASLAAELR

Sequences:

>Translated_318_residues
MRVGVMIGAERGDMARKVNKLVSDIEWAESAGLDTAWMPQVPNDFDCLTMVSLMAAHSSRIELGTAVVPLQAQHPIALAR
QALSTHAVAGGRLALGVGPSHHWIIRDMLGLPYQKPAAYTRDYLQVLNAAIAGPGPVDVENDSFTVHNPMVIGADTPMPV
LVAALGPVMLQIAGELADGTVLWMADERAIGEHIAPKITKAAADAGRPAPRIVAGIPVCLCAPSQVDEAKERANRILGEA
EVSPNYQRLLERGDARDVGDLCAAGEPEQILARMRRFADAGVTDLSVRLLPIGDNRDELVASKSRTREMIASLAAELR
>Mature_318_residues
MRVGVMIGAERGDMARKVNKLVSDIEWAESAGLDTAWMPQVPNDFDCLTMVSLMAAHSSRIELGTAVVPLQAQHPIALAR
QALSTHAVAGGRLALGVGPSHHWIIRDMLGLPYQKPAAYTRDYLQVLNAAIAGPGPVDVENDSFTVHNPMVIGADTPMPV
LVAALGPVMLQIAGELADGTVLWMADERAIGEHIAPKITKAAADAGRPAPRIVAGIPVCLCAPSQVDEAKERANRILGEA
EVSPNYQRLLERGDARDVGDLCAAGEPEQILARMRRFADAGVTDLSVRLLPIGDNRDELVASKSRTREMIASLAAELR

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 33947; Mature: 33947

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVGVMIGAERGDMARKVNKLVSDIEWAESAGLDTAWMPQVPNDFDCLTMVSLMAAHSSR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
IELGTAVVPLQAQHPIALARQALSTHAVAGGRLALGVGPSHHWIIRDMLGLPYQKPAAYT
EECCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCHHHH
RDYLQVLNAAIAGPGPVDVENDSFTVHNPMVIGADTPMPVLVAALGPVMLQIAGELADGT
HHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCE
VLWMADERAIGEHIAPKITKAAADAGRPAPRIVAGIPVCLCAPSQVDEAKERANRILGEA
EEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCC
EVSPNYQRLLERGDARDVGDLCAAGEPEQILARMRRFADAGVTDLSVRLLPIGDNRDELV
CCCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
ASKSRTREMIASLAAELR
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVGVMIGAERGDMARKVNKLVSDIEWAESAGLDTAWMPQVPNDFDCLTMVSLMAAHSSR
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
IELGTAVVPLQAQHPIALARQALSTHAVAGGRLALGVGPSHHWIIRDMLGLPYQKPAAYT
EECCCEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHCCCCCCCHHHH
RDYLQVLNAAIAGPGPVDVENDSFTVHNPMVIGADTPMPVLVAALGPVMLQIAGELADGT
HHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCE
VLWMADERAIGEHIAPKITKAAADAGRPAPRIVAGIPVCLCAPSQVDEAKERANRILGEA
EEEEECCHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCC
EVSPNYQRLLERGDARDVGDLCAAGEPEQILARMRRFADAGVTDLSVRLLPIGDNRDELV
CCCCCHHHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHH
ASKSRTREMIASLAAELR
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522533; 11930014; 1953299 [H]