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The map label for this gene is purL

Identifier: 41406733

GI number: 41406733

Start: 657343

End: 659640

Strand: Direct

Name: purL

Synonym: MAP0635

Alternate gene names: 41406733

Gene position: 657343-659640 (Clockwise)

Preceding gene: 41406731

Following gene: 41406734

Centisome position: 13.61

GC content: 70.71

Gene sequence:

>2298_bases
GTGACTGTCTCCCCGACGAGTGCGCCCACCCAGGCGATCGACACCGTCGAGCGCGCCGCGACCACCCCCGACGAGCCGCA
GCCCTTCGGCGAGTTGGGCCTCAAAGACGACGAATACCAGCGCATCCGCGAAATCCTGGGCCGCCGGCCCACCGACACCG
AGCTGGCGATGTACTCGGTGATGTGGAGCGAGCACTGCTCCTACAAGTCGTCCAAGGTGCACCTGCGCTACTTCGGGGAG
ACCACCACCGACGAGATGCGCGCCGGCATGCTGGCCGGCATCGGCGAGAACGCCGGCGTCGTCGACATCGGCGACGGCTG
GGCGGTCACCTTCAAGGTGGAATCGCACAACCACCCCTCCTACGTCGAGCCCTATCAGGGGGCGGCCACCGGCGTCGGCG
GCATCGTGCGCGACATCATGGCGATGGGCGCGCGCCCGGTGGCGGTGATGGACCAGCTTCGGTTCGGCGCCGCCGATGCG
CCGGACACCCGCCGCGTGCTCGACGGCGTGGTGCGCGGCATCGGCGGCTACGGCAACTCGCTGGGCCTGCCCAACATCGG
CGGCGAGACCGTCTTCGACGCCTGCTACGCCGGCAACCCGCTGGTGAACGCCATGTGCGTCGGCGTGTTACGCCAGGAGG
ACCTGCACATGGCCTTCGCCTCCGGCACGGGCAACAAGATCATCCTGTTCGGCGCCCGCACCGGGCTGGACGGCATCGGC
GGGGTATCGGTGCTGGCGTCGGACACCTTCGATGCGGAGAACTCGCGCAAGAAGCTGCCCTCGGTTCAGGTGGGCGACCC
GTTCATGGAGAAGGTGCTCATCGAGTGCTGCCTGGAGCTCTACGCCGGTGGGCTGGTGGTCGGCATCCAAGACCTGGGCG
GTGCCGGATTAGCTTGCGCCACTTCTGAATTGGCGTCCGCCGGGGACGGGGGGATGGAGGTCCGGCTGGAGGCCGTGCCG
CTGCGCACCGCCGGCATGACGCCCGCGGAGGTGCTGTGCAGCGAATCCCAGGAGCGGATGTGCGCGGTGGTCACACCGGA
GAACGTCGACGCCTTCCTGGCGGTGTGCCGCAAGTGGGACGTGCTGGCCACCGTGATCGGCGAGGTCACCGACGGCGACC
GGCTGCGGATCACCTGGCACGGGCAGACGGTGGTCGACGTGCCGCCGCGCACCGTCGCCCATGAAGGCCCGGTATACCAG
CGACCGCTCGCCCGCCCCGACACCCAGGACGCCCTGAACGCCGACAGCTCGGCACGGCTGCCCCGCCCGGCCACCGGCGC
CGAGCTGCGGGCCACTTTGCTTGCGCTGCTTGGCAGTCCGCACCTGTGCAGCCGCGCGTTCATCACCGAGCAGTACGACC
GGTATGTGCGCGGCAACACCGTGCTGGCCGAACACGCCGACGGCGGCGTGCTGCGCGTCGACGAGACCACCGGCCGCGGC
ATCGCCGTGTCCACCGACGCCTCGGGCCGCTACACCATGCTCGACCCCTACGCCGGTGCGCAGCTCGCGCTCGCCGAGGC
CTACCGCAACGTCGCCGTCACCGGCGCCACCCCGGTCGCGGTGACCAACTGCCTCAATTTCGGCTCGCCCGAAGACCCCG
CGGTGATGTGGCAGTTCGCCCAGGCGGTACGCGGGTTGGCGGATGGCTGTGTGGCCCTGGGGATTCCGGTGACCGGCGGC
AACGTCAGCTTCTACAACCAAACCGGGTCGGCGGCGATCCTGCCCACCCCGGTGGTGGGAGTGCTCGGCGTCCTCGACGA
TGTGAGCCGACGGCTGCCCACCGCCCTGGGCGCCGAGCCCGGCGAAACCCTGATGCTGCTCGGCGAGACCCGCGACGAGT
TCGACGGCTCGGTGTGGGCACAGGTGACCGCCGACCATCTGGGCGGTCTGCCGCCCAAGGTCGACCTGGCCCGCGAGAAG
CTGCTGGCCGAGGTGCTGCGCGCGGCGTCGCGCGACGGCCTGGTGTCCGCGGCGCACGACCTGTCCGAGGGCGGCCTGGC
CCAGGCCGTCGTCGAGGCTGCCCTGGCGGGCGAAACCGGTTGTCGCATCGTGCTTCCCGAGGACGCCGACCCGTTCGTGA
CGTTGTTCTCCGAGTCGGCGGGCCGGGTGCTGGTGGCGGTGCCGCGCACCGAGGAGAGCCGGTTCCGTTCCATGTGCGAG
GCGCGGGGACTGCCGGCGGTGCGCATCGGCGTCGTCGACCAGGCCTCCGACGAGGTCGAGGTGCAGGGGCTGTTCACGGT
TCCGTTGGCCGAATTGCGGCAGACCTCCGAGTCGGTGCTGCCCCGGCTGTTCGGATGA

Upstream 100 bases:

>100_bases
GACACAGGGCGGCTACCCGCCCACCCTGCGGACAAACCTTCGCCGCGGGCTGGCCCCGGCAGCGGCGCCGGCAGGGGCGG
TGCGCCATAGACTGGCGGGC

Downstream 100 bases:

>100_bases
ACATCCGCCGCCAAACCTGATGCGGCCCAGCCTTTTTCGTCGAACCGCCGCGCTGTCGTTGGCCGGCGCCCTGGTCGGCT
GGAGCTTCGCCGGCCCGCGG

Product: phosphoribosylformylglycinamidine synthase II

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase II; FGAM synthase II [H]

Number of amino acids: Translated: 765; Mature: 764

Protein sequence:

>765_residues
MTVSPTSAPTQAIDTVERAATTPDEPQPFGELGLKDDEYQRIREILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGE
TTTDEMRAGMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADA
PDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIG
GVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACATSELASAGDGGMEVRLEAVP
LRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWDVLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQ
RPLARPDTQDALNADSSARLPRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGVLRVDETTGRG
IAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFAQAVRGLADGCVALGIPVTGG
NVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVDLAREK
LLAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRIVLPEDADPFVTLFSESAGRVLVAVPRTEESRFRSMCE
ARGLPAVRIGVVDQASDEVEVQGLFTVPLAELRQTSESVLPRLFG

Sequences:

>Translated_765_residues
MTVSPTSAPTQAIDTVERAATTPDEPQPFGELGLKDDEYQRIREILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGE
TTTDEMRAGMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADA
PDTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIG
GVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACATSELASAGDGGMEVRLEAVP
LRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWDVLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQ
RPLARPDTQDALNADSSARLPRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGVLRVDETTGRG
IAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFAQAVRGLADGCVALGIPVTGG
NVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVDLAREK
LLAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRIVLPEDADPFVTLFSESAGRVLVAVPRTEESRFRSMCE
ARGLPAVRIGVVDQASDEVEVQGLFTVPLAELRQTSESVLPRLFG
>Mature_764_residues
TVSPTSAPTQAIDTVERAATTPDEPQPFGELGLKDDEYQRIREILGRRPTDTELAMYSVMWSEHCSYKSSKVHLRYFGET
TTDEMRAGMLAGIGENAGVVDIGDGWAVTFKVESHNHPSYVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAP
DTRRVLDGVVRGIGGYGNSLGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIGG
VSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACATSELASAGDGGMEVRLEAVPL
RTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWDVLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQR
PLARPDTQDALNADSSARLPRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGVLRVDETTGRGI
AVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFAQAVRGLADGCVALGIPVTGGN
VSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEPGETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVDLAREKL
LAEVLRAASRDGLVSAAHDLSEGGLAQAVVEAALAGETGCRIVLPEDADPFVTLFSESAGRVLVAVPRTEESRFRSMCEA
RGLPAVRIGVVDQASDEVEVQGLFTVPLAELRQTSESVLPRLFG

Specific function: Unknown

COG id: COG0046

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGAMS family [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=743, Percent_Identity=24.4952893674293, Blast_Score=100, Evalue=9e-21,
Organism=Escherichia coli, GI48994899, Length=772, Percent_Identity=26.8134715025907, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553022, Length=746, Percent_Identity=23.1903485254692, Blast_Score=117, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321498, Length=813, Percent_Identity=25.2152521525215, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24582111, Length=724, Percent_Identity=24.3093922651934, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24582109, Length=724, Percent_Identity=24.3093922651934, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17137292, Length=724, Percent_Identity=24.3093922651934, Blast_Score=114, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR010074
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 80707; Mature: 80576

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSPTSAPTQAIDTVERAATTPDEPQPFGELGLKDDEYQRIREILGRRPTDTELAMYSV
CCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
MWSEHCSYKSSKVHLRYFGETTTDEMRAGMLAGIGENAGVVDIGDGWAVTFKVESHNHPS
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEECCCCCC
YVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNS
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
LGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIG
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCC
GVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACA
CEEEEECCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
TSELASAGDGGMEVRLEAVPLRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWD
HHHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
VLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQRPLARPDTQDALNADSSARL
HHHHHHHCCCCCCEEEEEECCCEEEECCCCHHCCCCCCCCCCCCCCCCHHHHCCCCCCCC
PRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGVLRVDETTGRG
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCE
IAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFA
EEEEECCCCCEEEECCCCCCHHHHHHHHHCEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
QAVRGLADGCVALGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEP
HHHHHHHCCCEEEEEEECCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHCCHHHCCCC
GETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVDLAREKLLAEVLRAASRDGLVSAAHD
CCEEEEEECCCCCCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSEGGLAQAVVEAALAGETGCRIVLPEDADPFVTLFSESAGRVLVAVPRTEESRFRSMCE
CCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHH
ARGLPAVRIGVVDQASDEVEVQGLFTVPLAELRQTSESVLPRLFG
HCCCCEEEEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVSPTSAPTQAIDTVERAATTPDEPQPFGELGLKDDEYQRIREILGRRPTDTELAMYSV
CCCCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHH
MWSEHCSYKSSKVHLRYFGETTTDEMRAGMLAGIGENAGVVDIGDGWAVTFKVESHNHPS
HHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEECCCCEEEEEEEECCCCCC
YVEPYQGAATGVGGIVRDIMAMGARPVAVMDQLRFGAADAPDTRRVLDGVVRGIGGYGNS
CCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCC
LGLPNIGGETVFDACYAGNPLVNAMCVGVLRQEDLHMAFASGTGNKIILFGARTGLDGIG
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCCCCCCCC
GVSVLASDTFDAENSRKKLPSVQVGDPFMEKVLIECCLELYAGGLVVGIQDLGGAGLACA
CEEEEECCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHH
TSELASAGDGGMEVRLEAVPLRTAGMTPAEVLCSESQERMCAVVTPENVDAFLAVCRKWD
HHHHHHCCCCCEEEEEEEEEEECCCCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHH
VLATVIGEVTDGDRLRITWHGQTVVDVPPRTVAHEGPVYQRPLARPDTQDALNADSSARL
HHHHHHHCCCCCCEEEEEECCCEEEECCCCHHCCCCCCCCCCCCCCCCHHHHCCCCCCCC
PRPATGAELRATLLALLGSPHLCSRAFITEQYDRYVRGNTVLAEHADGGVLRVDETTGRG
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCE
IAVSTDASGRYTMLDPYAGAQLALAEAYRNVAVTGATPVAVTNCLNFGSPEDPAVMWQFA
EEEEECCCCCEEEECCCCCCHHHHHHHHHCEEEECCCHHHHHHHHCCCCCCCHHHHHHHH
QAVRGLADGCVALGIPVTGGNVSFYNQTGSAAILPTPVVGVLGVLDDVSRRLPTALGAEP
HHHHHHHCCCEEEEEEECCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHCCHHHCCCC
GETLMLLGETRDEFDGSVWAQVTADHLGGLPPKVDLAREKLLAEVLRAASRDGLVSAAHD
CCEEEEEECCCCCCCCCEEEEEEHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSEGGLAQAVVEAALAGETGCRIVLPEDADPFVTLFSESAGRVLVAVPRTEESRFRSMCE
CCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCCCEEEEEECCCHHHHHHHHHH
ARGLPAVRIGVVDQASDEVEVQGLFTVPLAELRQTSESVLPRLFG
HCCCCEEEEEEECCCCCCEEEEEEEECCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA