| Definition | Mycobacterium avium subsp. paratuberculosis K-10, complete genome. |
|---|---|
| Accession | NC_002944 |
| Length | 4,829,781 |
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The map label for this gene is gdh [H]
Identifier: 41406676
GI number: 41406676
Start: 602854
End: 603645
Strand: Direct
Name: gdh [H]
Synonym: MAP0578
Alternate gene names: 41406676
Gene position: 602854-603645 (Clockwise)
Preceding gene: 41406675
Following gene: 41406680
Centisome position: 12.48
GC content: 71.72
Gene sequence:
>792_bases ATGAAAAGGCTTGAGGGCAAACGGATTTTGGTGACCGGCGCCGCGTCGGGCATCGGCCAGGCGACCGCGCTGCGGTTGCT GGACGAGGGCGCCGCGGTGGCCGCCTCCGACGTCGCCGTCGACGGGCTGGAGCGGACCCGCGACCGGGCGGCGCAGGCAG GCACCGCCGAGCGGCTGGTCACCGTGACCATGGACGTGGGCCGCGAGGACGCGGTGGTCGATGGCGTGCGCGTCGCCGTC GCGCAGCTGGGCGGCCTGGATTCGCTGGTCAACGCCGCCGGCATGCTGCGCGCCGCGCACACCCACCAGACCAGCCTGCA GCTGTGGAACCAGATCATCGGCGTCAACCTGACCGGGACCTTCCTGGTGGTCCGGGAGGCGCTGCCGGCGCTGCTGGACA ACGCGCGCAGCGCGGTGGTGAACTTCAGCTCCACGTCGGCCTCGTTCGCCCACCCCTATATGGCCGCCTACGCCGCGAGC AAGGGCGGCATCCAGGCCTTCACCCACTCGCTGGCGCTGGAATACGCGCGCCGGGGCCTGCGCGCGGTGTGCGTGGCGCC GGGCAGCATCAAGTCCGGCATCACCGACGCCACCGGCGGCTACATCCCCGAAGACGCCGACTGGTCGCTGTTTTCGCGGT TGCTGCCGGTGCTGCCGACCACGGTGGAATCCAGCGGCACCGGGATGGCCGAGCCCACCGCCGTCGCCGGGGTGATCGCC ATGCTGGTGTCCGACGACGGCGCGTTCATCACCGGCACCGAGATCCGCATCGACGGCGGAACCCACGCCTGA
Upstream 100 bases:
>100_bases GCGGCCACATGTTGCGTCGCGGCCCCGACTACTCGTCGATGATGGTGCAGATGTTCGGCCAGGACGCGCTGCGCGGCGTG GTCTGAGCCGGGAGAATCGC
Downstream 100 bases:
>100_bases GAGTTCAGTTCACGCACGGCACGCCGCCGCCGTCGATCGGTTTCCCCTGATCCGGCGTCGGATACGTGGTGGTGGTGCCG TTGTAGTAGTAGGTCTTGGC
Product: hypothetical protein
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 263; Mature: 263
Protein sequence:
>263_residues MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAASDVAVDGLERTRDRAAQAGTAERLVTVTMDVGREDAVVDGVRVAV AQLGGLDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGTFLVVREALPALLDNARSAVVNFSSTSASFAHPYMAAYAAS KGGIQAFTHSLALEYARRGLRAVCVAPGSIKSGITDATGGYIPEDADWSLFSRLLPVLPTTVESSGTGMAEPTAVAGVIA MLVSDDGAFITGTEIRIDGGTHA
Sequences:
>Translated_263_residues MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAASDVAVDGLERTRDRAAQAGTAERLVTVTMDVGREDAVVDGVRVAV AQLGGLDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGTFLVVREALPALLDNARSAVVNFSSTSASFAHPYMAAYAAS KGGIQAFTHSLALEYARRGLRAVCVAPGSIKSGITDATGGYIPEDADWSLFSRLLPVLPTTVESSGTGMAEPTAVAGVIA MLVSDDGAFITGTEIRIDGGTHA >Mature_263_residues MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAASDVAVDGLERTRDRAAQAGTAERLVTVTMDVGREDAVVDGVRVAV AQLGGLDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGTFLVVREALPALLDNARSAVVNFSSTSASFAHPYMAAYAAS KGGIQAFTHSLALEYARRGLRAVCVAPGSIKSGITDATGGYIPEDADWSLFSRLLPVLPTTVESSGTGMAEPTAVAGVIA MLVSDDGAFITGTEIRIDGGTHA
Specific function: Unknown
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=270, Percent_Identity=31.4814814814815, Blast_Score=103, Evalue=2e-22, Organism=Homo sapiens, GI19923817, Length=263, Percent_Identity=29.277566539924, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI5031737, Length=251, Percent_Identity=30.2788844621514, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI32483357, Length=266, Percent_Identity=30.4511278195489, Blast_Score=88, Evalue=8e-18, Organism=Homo sapiens, GI59889578, Length=207, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4758504, Length=271, Percent_Identity=29.520295202952, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI33667109, Length=184, Percent_Identity=34.2391304347826, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI66933014, Length=265, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI7706318, Length=193, Percent_Identity=26.4248704663212, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI19743808, Length=202, Percent_Identity=32.1782178217822, Blast_Score=79, Evalue=6e-15, Organism=Homo sapiens, GI150247226, Length=199, Percent_Identity=33.1658291457286, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI44680136, Length=206, Percent_Identity=32.0388349514563, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI44680133, Length=206, Percent_Identity=32.0388349514563, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI17738292, Length=206, Percent_Identity=32.0388349514563, Blast_Score=75, Evalue=9e-14, Organism=Homo sapiens, GI4504505, Length=201, Percent_Identity=29.3532338308458, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI142976729, Length=196, Percent_Identity=25, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI22507405, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI40807363, Length=220, Percent_Identity=26.3636363636364, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI109715829, Length=212, Percent_Identity=26.4150943396226, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI31542939, Length=250, Percent_Identity=26, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI83715985, Length=192, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI210032110, Length=222, Percent_Identity=22.972972972973, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=25.4681647940075, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=26.4, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI40548397, Length=228, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI214010158, Length=228, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI214010156, Length=228, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI22758144, Length=228, Percent_Identity=29.8245614035088, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI226371731, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=3e-11, Organism=Escherichia coli, GI87082100, Length=263, Percent_Identity=30.0380228136882, Blast_Score=103, Evalue=2e-23, Organism=Escherichia coli, GI1786812, Length=260, Percent_Identity=31.1538461538462, Blast_Score=100, Evalue=7e-23, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=30.1158301158301, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=27.2373540856031, Blast_Score=97, Evalue=2e-21, Organism=Escherichia coli, GI2367175, Length=257, Percent_Identity=34.6303501945525, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1789208, Length=258, Percent_Identity=26.3565891472868, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=26.8939393939394, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI87082160, Length=195, Percent_Identity=27.6923076923077, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=25.1366120218579, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1788459, Length=259, Percent_Identity=23.9382239382239, Blast_Score=69, Evalue=3e-13, Organism=Escherichia coli, GI2367365, Length=259, Percent_Identity=28.1853281853282, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786701, Length=191, Percent_Identity=27.2251308900524, Blast_Score=62, Evalue=5e-11, Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=23.6434108527132, Blast_Score=61, Evalue=7e-11, Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=31.3492063492063, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17562904, Length=269, Percent_Identity=30.1115241635688, Blast_Score=105, Evalue=3e-23, Organism=Caenorhabditis elegans, GI17562906, Length=271, Percent_Identity=30.6273062730627, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=28.6821705426357, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562990, Length=267, Percent_Identity=29.5880149812734, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17559104, Length=273, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17561402, Length=266, Percent_Identity=30.0751879699248, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560150, Length=270, Percent_Identity=28.5185185185185, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=28.7822878228782, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=29.0441176470588, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=29.8892988929889, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI25147288, Length=263, Percent_Identity=30.0380228136882, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17544670, Length=200, Percent_Identity=29.5, Blast_Score=88, Evalue=6e-18, Organism=Caenorhabditis elegans, GI72000259, Length=272, Percent_Identity=28.6764705882353, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17563726, Length=275, Percent_Identity=28.7272727272727, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=27.5092936802974, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17562910, Length=272, Percent_Identity=26.8382352941176, Blast_Score=84, Evalue=6e-17, Organism=Caenorhabditis elegans, GI17560332, Length=273, Percent_Identity=26.7399267399267, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17560676, Length=268, Percent_Identity=27.6119402985075, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17564282, Length=196, Percent_Identity=27.5510204081633, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17538486, Length=269, Percent_Identity=28.996282527881, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=26.3940520446097, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17536651, Length=264, Percent_Identity=29.9242424242424, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17555706, Length=261, Percent_Identity=27.5862068965517, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17536025, Length=267, Percent_Identity=30.7116104868914, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=271, Percent_Identity=26.5682656826568, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI193203115, Length=252, Percent_Identity=26.1904761904762, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI193203117, Length=251, Percent_Identity=25.8964143426295, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17538182, Length=271, Percent_Identity=27.3062730627306, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17508895, Length=252, Percent_Identity=25, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17565030, Length=276, Percent_Identity=26.4492753623188, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=27.979274611399, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI71982365, Length=146, Percent_Identity=30.8219178082192, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI17561272, Length=271, Percent_Identity=30.6273062730627, Blast_Score=64, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=26.9035532994924, Blast_Score=70, Evalue=4e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=266, Percent_Identity=24.0601503759398, Blast_Score=69, Evalue=9e-13, Organism=Saccharomyces cerevisiae, GI6322227, Length=251, Percent_Identity=27.4900398406374, Blast_Score=69, Evalue=1e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=184, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=3e-12, Organism=Saccharomyces cerevisiae, GI6322226, Length=188, Percent_Identity=29.7872340425532, Blast_Score=64, Evalue=2e-11, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=32.5670498084291, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI21357041, Length=263, Percent_Identity=31.5589353612167, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI28571526, Length=263, Percent_Identity=31.9391634980989, Blast_Score=105, Evalue=3e-23, Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=30, Blast_Score=101, Evalue=6e-22, Organism=Drosophila melanogaster, GI23397609, Length=263, Percent_Identity=33.4600760456274, Blast_Score=98, Evalue=7e-21, Organism=Drosophila melanogaster, GI21355319, Length=271, Percent_Identity=30.6273062730627, Blast_Score=97, Evalue=2e-20, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI18859837, Length=224, Percent_Identity=29.9107142857143, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI24644337, Length=180, Percent_Identity=30, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI24665243, Length=220, Percent_Identity=32.7272727272727, Blast_Score=76, Evalue=3e-14, Organism=Drosophila melanogaster, GI221331218, Length=220, Percent_Identity=32.7272727272727, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24643142, Length=260, Percent_Identity=30, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI21357673, Length=216, Percent_Identity=26.8518518518519, Blast_Score=72, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665247, Length=221, Percent_Identity=32.579185520362, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI221331216, Length=221, Percent_Identity=32.579185520362, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI28574402, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24584744, Length=202, Percent_Identity=29.2079207920792, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=200, Percent_Identity=27.5, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI24641388, Length=212, Percent_Identity=29.2452830188679, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.47 [H]
Molecular weight: Translated: 27087; Mature: 27087
Theoretical pI: Translated: 5.63; Mature: 5.63
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAASDVAVDGLERTRDRAAQAGTAERLV CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEE TVTMDVGREDAVVDGVRVAVAQLGGLDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGT EEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH FLVVREALPALLDNARSAVVNFSSTSASFAHPYMAAYAASKGGIQAFTHSLALEYARRGL HHHHHHHHHHHHHCHHHHEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCC RAVCVAPGSIKSGITDATGGYIPEDADWSLFSRLLPVLPTTVESSGTGMAEPTAVAGVIA EEEEECCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH MLVSDDGAFITGTEIRIDGGTHA HHCCCCCCEEECCEEEECCCCCC >Mature Secondary Structure MKRLEGKRILVTGAASGIGQATALRLLDEGAAVAASDVAVDGLERTRDRAAQAGTAERLV CCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHCCCCCEEE TVTMDVGREDAVVDGVRVAVAQLGGLDSLVNAAGMLRAAHTHQTSLQLWNQIIGVNLTGT EEEECCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH FLVVREALPALLDNARSAVVNFSSTSASFAHPYMAAYAASKGGIQAFTHSLALEYARRGL HHHHHHHHHHHHHCHHHHEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCC RAVCVAPGSIKSGITDATGGYIPEDADWSLFSRLLPVLPTTVESSGTGMAEPTAVAGVIA EEEEECCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH MLVSDDGAFITGTEIRIDGGTHA HHCCCCCCEEECCEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 3082854; 8969502; 9384377 [H]