Click here to switch to the map view.

The map label for this gene is mhpF [C]

Identifier: 41406630

GI number: 41406630

Start: 558459

End: 559376

Strand: Direct

Name: mhpF [C]

Synonym: MAP0532

Alternate gene names: 41406630

Gene position: 558459-559376 (Clockwise)

Preceding gene: 41406629

Following gene: 41406631

Centisome position: 11.56

GC content: 68.52

Gene sequence:

>918_bases
ATGCCGACTAAAGCAAAAGTGGCGATTGTCGGGTCGGGGAACATCAGCACGGACCTGCTCTACAAGCTGCTGCGATCCGA
CTGGCTGGAACCACGCTGGATGGTCGGCATCGACCCGCAGAGCGAGGGCCTGGCCCGGGCCCGCAAGCTGGGCTTGGAGA
CCACCCACGAGGGGGTCGACTGGCTGCTGGCGCAGCCGGAGAAACCCGACCTGGTCTTCGAGGCGACCAGCGCTTACGTG
CACCGCGACGCCGCCCCCAAGTACGAGGCCGCCGGCATCCGGGCCATCGACCTGACGCCCGCCGCGGTGGGCCCGGCCGT
CATCCCGCCGGCGAACCTGCGCCAGCACCTGGACGCGCCGAACGTCAACATGATCACCTGCGGCGGGCAGGCCACGATCC
CGATCGTCTTCGCCGTCAGCCGCGTCGTCGAGGTGCCCTACGCCGAGATCGTCGCGTCGGTGGCGAGCGTGTCGGCGGGC
CCGGGCACCCGTGCCAACATCGACGAGTTCACCAAGACCACCAGCCGGGGCGTGGAGACCATCGGCGGCGCCAAGCGGGG
CAAGGCGATCATCATCCTCAACCCGGCCGACCCGCCGATGATCATGCGCGACACCATCTTCTGCGCTATCCCCGAGGACG
CCGACCGGGACGCGATCGCACAGTCGATTCACGACGTCGTCAAAGAGGTGCAGACCTACGTGCCCGGCTACCGGCTGCTC
AACGAGCCGCAGTTCGACGAGCCGTCGCTCAACTCCGGTGGCCAGGCCGTGGTCACCACGTTCGTCGAGGTCGAGGGCGC
CGGCGATTATCTGCCCCCGTACGCGGGCAACCTGGACATCATGACCGCCGCGGCCACCAAGGTCGGCGAGGAGATCGCCA
AGGAGACGCTGGCCACGACGGCGGGAGGAGCGCAATGA

Upstream 100 bases:

>100_bases
CGTCGCCGACTTCGCGGGCCTGGGTTCGGTGTGTCTGTCGTTCGAATAGGCTCGAGTTAAATCGACCAACTTAAATCTCA
ACAGCTTCGTAAGGAGCGTC

Downstream 100 bases:

>100_bases
CTACCGATATCTTCTTCAACCCGATTTGGGACGTCCGGCTGACCGACACGTCGCTGCGCGACGGCAGCCACCACAAGCGC
CACCAGTTCACCAAGGACGA

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 2 [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MPTKAKVAIVGSGNISTDLLYKLLRSDWLEPRWMVGIDPQSEGLARARKLGLETTHEGVDWLLAQPEKPDLVFEATSAYV
HRDAAPKYEAAGIRAIDLTPAAVGPAVIPPANLRQHLDAPNVNMITCGGQATIPIVFAVSRVVEVPYAEIVASVASVSAG
PGTRANIDEFTKTTSRGVETIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQTYVPGYRLL
NEPQFDEPSLNSGGQAVVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLATTAGGAQ

Sequences:

>Translated_305_residues
MPTKAKVAIVGSGNISTDLLYKLLRSDWLEPRWMVGIDPQSEGLARARKLGLETTHEGVDWLLAQPEKPDLVFEATSAYV
HRDAAPKYEAAGIRAIDLTPAAVGPAVIPPANLRQHLDAPNVNMITCGGQATIPIVFAVSRVVEVPYAEIVASVASVSAG
PGTRANIDEFTKTTSRGVETIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQTYVPGYRLL
NEPQFDEPSLNSGGQAVVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLATTAGGAQ
>Mature_304_residues
PTKAKVAIVGSGNISTDLLYKLLRSDWLEPRWMVGIDPQSEGLARARKLGLETTHEGVDWLLAQPEKPDLVFEATSAYVH
RDAAPKYEAAGIRAIDLTPAAVGPAVIPPANLRQHLDAPNVNMITCGGQATIPIVFAVSRVVEVPYAEIVASVASVSAGP
GTRANIDEFTKTTSRGVETIGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQTYVPGYRLLN
EPQFDEPSLNSGGQAVVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLATTAGGAQ

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds [H]

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1786547, Length=316, Percent_Identity=56.6455696202532, Blast_Score=324, Evalue=6e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534 [H]

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh [H]

EC number: =1.2.1.10 [H]

Molecular weight: Translated: 32339; Mature: 32208

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKAKVAIVGSGNISTDLLYKLLRSDWLEPRWMVGIDPQSEGLARARKLGLETTHEGVD
CCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
WLLAQPEKPDLVFEATSAYVHRDAAPKYEAAGIRAIDLTPAAVGPAVIPPANLRQHLDAP
EEEECCCCCCEEEEEHHHHHCCCCCCCCHHCCEEEEECCCHHCCCCCCCCHHHHHHCCCC
NVNMITCGGQATIPIVFAVSRVVEVPYAEIVASVASVSAGPGTRANIDEFTKTTSRGVET
CCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
IGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQTYVPGYRLL
HCCCCCCCEEEEECCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
NEPQFDEPSLNSGGQAVVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLATT
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHC
AGGAQ
CCCCC
>Mature Secondary Structure 
PTKAKVAIVGSGNISTDLLYKLLRSDWLEPRWMVGIDPQSEGLARARKLGLETTHEGVD
CCCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCCC
WLLAQPEKPDLVFEATSAYVHRDAAPKYEAAGIRAIDLTPAAVGPAVIPPANLRQHLDAP
EEEECCCCCCEEEEEHHHHHCCCCCCCCHHCCEEEEECCCHHCCCCCCCCHHHHHHCCCC
NVNMITCGGQATIPIVFAVSRVVEVPYAEIVASVASVSAGPGTRANIDEFTKTTSRGVET
CCEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
IGGAKRGKAIIILNPADPPMIMRDTIFCAIPEDADRDAIAQSIHDVVKEVQTYVPGYRLL
HCCCCCCCEEEEECCCCCCEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCHHHC
NEPQFDEPSLNSGGQAVVTTFVEVEGAGDYLPPYAGNLDIMTAAATKVGEEIAKETLATT
CCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHC
AGGAQ
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA