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The map label for this gene is celR [H]

Identifier: 41406588

GI number: 41406588

Start: 517277

End: 518473

Strand: Direct

Name: celR [H]

Synonym: MAP0490

Alternate gene names: 41406588

Gene position: 517277-518473 (Clockwise)

Preceding gene: 41406581

Following gene: 41406590

Centisome position: 10.71

GC content: 71.18

Gene sequence:

>1197_bases
ATGTCCTCCCGCCGGCCAGCCAGCCGATGCACAATACTAATGAAAATCGTTTCCATTACAAAGCCGGCCGGGGAAGCGCG
TACGCGAGCGCACCGATCCGCTGTAGCGTCACCGAGCGTGAGTCCCACCCCGCGCCGGCGGGCGACTCTGGCGTCGCTGG
CCGACGAACTCAAGGTCTCGCGCACGACGGTGTCGAACGCCTTCAACCGGCCCGATCAGCTGTCCGCGGACCTGCGTGAG
CGGGTGCTCGCGACGGCCAAGCGGCTGGGCTACCCCGGCCCCGACCCGGTGGCGCGGTCGTTGCGGACCCGCAAGGCCGG
CGCGGTCGGTCTGGTGATGGCCGAACCGCTGACCTACTTCTTCAGCGACCCCGCCGCCCGCGACTTCGTCACCGGGGTGG
CGCAGTCCTGCGAGGCGCTGGGGCAGGGGCTGCTGCTGGTCGCCGTCGGGCCCAGCCGCAGCCTGGATGAGGGAACCGCC
GCGGTGCTGTCGGCCGGGGTGGACGGCTTCGTGGTGTATTCGGTGTGTGACGACGACCCCTACCTGCAGGCCGTGTTGCA
GCGGCGGCTGCCGGTGGTGGTGGTCGACCAGCCCAAGGGACTGACCGGGGTGTCGCGGGTGGGCATCGACGACCGCGCGG
CGATGCGGGAGCTCGCCGACTACGTGCTCGGCTTGGGGCATCGCGAGATCGGGCTGCTGACCATGCGGCTGGGCCGGGAC
CGCCGCCAGGGCCTGGTGGACGCCGAACGGCTGCGTTCGCCCGCCTTCGACGTGCAGCGCGAGCGCATCACCGGGGTGTG
GGAGGCGATGACGGCCGCCGGCGTCGACCCGGATTCGCTGACCGTGGTGGAGAGCTACGAACACCTGCCCGAGTCGGGCG
GCGCGGCCGCCAAGGTGGCGCTGGAGGCCAACCCGCGGATCACCGCGCTGATGTGCACCGCCGACATCCTGGCCCTGTCG
GCCATGGATTACCTACGCGCCCATGGTGTTTACGTGCCCGGGCAGCTGACGGTGACCGGATTCGACGGCGTGCCCGACGC
GATCAGCCGGGGCCTGACCACGGTGTCGCAGTCCAGCCTGCACAAGGGCAGCCGGGCCGGTGAGTTGCTGCTCAAGCCGG
CACGGTCGGGCCTGCCGGTGGTCGAGCTGCTCGACACCGAGCTGATTCGCGGCCGTACCGCCGGTCCGCCGGCCTAG

Upstream 100 bases:

>100_bases
GTCAGCGCCGCCCAGCCGGTCACCGCCAGCACGGCCGCCAGCCACCGCGTCGTGCGGCCGACCCGCGTTGCGTCCCGCGT
CAGTGCCGTGCCCACGTCCG

Downstream 100 bases:

>100_bases
CCGTGCTCGCCGAGCAGCAACCGCACCGCCAGATCGAGGCGCTTGCTGACGTCGGTGGCCGAGGCGCGCCGGGTCAGCCA
GGCGAGCAGGTTGGACAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSSRRPASRCTILMKIVSITKPAGEARTRAHRSAVASPSVSPTPRRRATLASLADELKVSRTTVSNAFNRPDQLSADLRE
RVLATAKRLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSCEALGQGLLLVAVGPSRSLDEGTA
AVLSAGVDGFVVYSVCDDDPYLQAVLQRRLPVVVVDQPKGLTGVSRVGIDDRAAMRELADYVLGLGHREIGLLTMRLGRD
RRQGLVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDSLTVVESYEHLPESGGAAAKVALEANPRITALMCTADILALS
AMDYLRAHGVYVPGQLTVTGFDGVPDAISRGLTTVSQSSLHKGSRAGELLLKPARSGLPVVELLDTELIRGRTAGPPA

Sequences:

>Translated_398_residues
MSSRRPASRCTILMKIVSITKPAGEARTRAHRSAVASPSVSPTPRRRATLASLADELKVSRTTVSNAFNRPDQLSADLRE
RVLATAKRLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSCEALGQGLLLVAVGPSRSLDEGTA
AVLSAGVDGFVVYSVCDDDPYLQAVLQRRLPVVVVDQPKGLTGVSRVGIDDRAAMRELADYVLGLGHREIGLLTMRLGRD
RRQGLVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDSLTVVESYEHLPESGGAAAKVALEANPRITALMCTADILALS
AMDYLRAHGVYVPGQLTVTGFDGVPDAISRGLTTVSQSSLHKGSRAGELLLKPARSGLPVVELLDTELIRGRTAGPPA
>Mature_397_residues
SSRRPASRCTILMKIVSITKPAGEARTRAHRSAVASPSVSPTPRRRATLASLADELKVSRTTVSNAFNRPDQLSADLRER
VLATAKRLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYFFSDPAARDFVTGVAQSCEALGQGLLLVAVGPSRSLDEGTAA
VLSAGVDGFVVYSVCDDDPYLQAVLQRRLPVVVVDQPKGLTGVSRVGIDDRAAMRELADYVLGLGHREIGLLTMRLGRDR
RQGLVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDSLTVVESYEHLPESGGAAAKVALEANPRITALMCTADILALSA
MDYLRAHGVYVPGQLTVTGFDGVPDAISRGLTTVSQSSLHKGSRAGELLLKPARSGLPVVELLDTELIRGRTAGPPA

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=335, Percent_Identity=29.8507462686567, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1790369, Length=364, Percent_Identity=26.3736263736264, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994940, Length=300, Percent_Identity=25.3333333333333, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789068, Length=304, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1790194, Length=333, Percent_Identity=26.7267267267267, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789202, Length=302, Percent_Identity=26.4900662251656, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787580, Length=288, Percent_Identity=21.875, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 42294; Mature: 42163

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRRPASRCTILMKIVSITKPAGEARTRAHRSAVASPSVSPTPRRRATLASLADELKVS
CCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RTTVSNAFNRPDQLSADLRERVLATAKRLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYF
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHH
FSDPAARDFVTGVAQSCEALGQGLLLVAVGPSRSLDEGTAAVLSAGVDGFVVYSVCDDDP
HCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCH
YLQAVLQRRLPVVVVDQPKGLTGVSRVGIDDRAAMRELADYVLGLGHREIGLLTMRLGRD
HHHHHHHHCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCH
RRQGLVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDSLTVVESYEHLPESGGAAAKVA
HHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEE
LEANPRITALMCTADILALSAMDYLRAHGVYVPGQLTVTGFDGVPDAISRGLTTVSQSSL
EECCCCEEEEHHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCHHHHHHHHHHHHHHHH
HKGSRAGELLLKPARSGLPVVELLDTELIRGRTAGPPA
HCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSRRPASRCTILMKIVSITKPAGEARTRAHRSAVASPSVSPTPRRRATLASLADELKVS
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
RTTVSNAFNRPDQLSADLRERVLATAKRLGYPGPDPVARSLRTRKAGAVGLVMAEPLTYF
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCEEEEHHHHHHHH
FSDPAARDFVTGVAQSCEALGQGLLLVAVGPSRSLDEGTAAVLSAGVDGFVVYSVCDDDP
HCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEEEECCCH
YLQAVLQRRLPVVVVDQPKGLTGVSRVGIDDRAAMRELADYVLGLGHREIGLLTMRLGRD
HHHHHHHHCCCEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCH
RRQGLVDAERLRSPAFDVQRERITGVWEAMTAAGVDPDSLTVVESYEHLPESGGAAAKVA
HHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEEEE
LEANPRITALMCTADILALSAMDYLRAHGVYVPGQLTVTGFDGVPDAISRGLTTVSQSSL
EECCCCEEEEHHHHHHHHHHHHHHHHHCCEECCCEEEEECCCCCHHHHHHHHHHHHHHHH
HKGSRAGELLLKPARSGLPVVELLDTELIRGRTAGPPA
HCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]