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The map label for this gene is 41406563

Identifier: 41406563

GI number: 41406563

Start: 492766

End: 494205

Strand: Direct

Name: 41406563

Synonym: MAP0465

Alternate gene names: NA

Gene position: 492766-494205 (Clockwise)

Preceding gene: 41406562

Following gene: 41406566

Centisome position: 10.2

GC content: 63.54

Gene sequence:

>1440_bases
ATGGCCAACCGCTACCTGCAGGGTCCATTCGCCCCGATGCATCACGAGTACACGCTGACCGGTTTGGAGGTCGTCGGGAC
GATCCCGGATTACCTGGATGGGCGGTATCTGCGCAACGGTGCCAACCCAATCGGAGACGTCGATCCTGAGCGTTATCACT
GGTTCCTGGGCGACGGCATGGTGCACGGCATCCGAATCCGTGACGGCAAGGCCGAGTGGTACCGCAACCGTTGGGTGCGC
AGCCCAGCCACCTCGAAAGCCCTCGGCCAGCCCGCACCGCCGGGTCACTTCGGCTTTTTTCCAATCGGCGCCAATACCAA
CGTAATCGGGCATGCCGGCAAGACACTCGCATTGATCGAAGGCGGCATCGCCAACTATGAACTCACCGAGGAATTGGACA
CCGTCGGCGTGTGCGACTTCGCCGGAACGCTCACCGGCGGGTACGCAGCGCACCCCCATCGTGACCCCGAGACGGGTGAG
CTGCATGCGGTTTCGTACAACCCCTATCGCGGCAACAGGGTGCAGTATTCGGTGATCGACGTCGAGGGTCGAGCGCGACG
GACCGTCAACGTCACCGTTGGCGGCAGCCCGATGATGCATGACTTTTCCCTGACTGAACGCTATGTCGTGTTCTACGACC
TGCCGGTCACCTTCGATGAGGCGGTGGGCGCGGCCATGACGGCGCCGCGCGGGCTTCGGCCGATCGCCCGGCTGATGCTG
TCGGCGCTGATCGGCCGGGTCGCCATTCCCGATCCCATCGCCGCGCGGCTGCCGGCGGCGACCACGGACCGGCGAATGCC
CTACTCGTGGAACCCGAACTACCCGGCCCGTGTCGGCGTGATGCCACGCGACGGTGAAGATGCCGATGTGCGCTGGTTCG
ACGTCGAACCGTGCTACGTATTCCATCCGATGAATGCCTACGAAGAGGATGGCACCATCGTGCTCGACGTAGTGCGAAAC
CCCAAGATGTTCGACCGGGACCGCACCGGTCCCAATGAGGGGCCACCCACGTTGGACCGTTGGGTGATCGATTTGGCGGC
CGGGAAGGTGCGCGAATCCCGCATTGATGATCGGGGCCAGGAGTTTCCGCGCATCGACGAGCGCCTGGTTGGAAAGCGGC
ATCGTTACGGCTACACGCCGACGGTGCTGGAGGGCATCGAAGGCGGGGACTGCTTGCTCAAGCACGATCTTATTGGCGGG
AGCACCCAGTCGCGCTGCCTGGGTCCGCAAAAAGCATTGGGCGAGTTTGTGTTTCACCCTTCATCGCCGGCCGCCGCGGA
AGACGAGGGCGTGCTGATGGGCTATGTGTACGACCGGGCCACCAATCGCAGCGAGTTGGCGATCCTCGATGCTCAAACCC
TCGAGGACGTTGCCAGCATCAAGCTGCCGCATCGAGTTCCCGCCGGTTTCCATGGCAACTGGGTGCCCAGCACCAACTAG

Upstream 100 bases:

>100_bases
CGGGACGGCGCACGCCAAACTTGACACATGTCAAGTTTGGCGGCAGGATGGTCGTCCACGAGCGCAACCAACAGCGTGTC
GCTCAGGTAGGAGGTCTGTT

Downstream 100 bases:

>100_bases
CGGCCGCCGCGACTAGCGCGGCGCGATCAGCGCGAAGGCCTGTTTGGCCACCTGCAGCATCCAGCCCGTCGCGGTCGGGC
CGTGATCGCGCGGCCAGTTC

Product: hypothetical protein

Products: NA

Alternate protein names: ACO; 8'-apo-beta-carotenal 15,15'-oxygenase; Diox1 [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MANRYLQGPFAPMHHEYTLTGLEVVGTIPDYLDGRYLRNGANPIGDVDPERYHWFLGDGMVHGIRIRDGKAEWYRNRWVR
SPATSKALGQPAPPGHFGFFPIGANTNVIGHAGKTLALIEGGIANYELTEELDTVGVCDFAGTLTGGYAAHPHRDPETGE
LHAVSYNPYRGNRVQYSVIDVEGRARRTVNVTVGGSPMMHDFSLTERYVVFYDLPVTFDEAVGAAMTAPRGLRPIARLML
SALIGRVAIPDPIAARLPAATTDRRMPYSWNPNYPARVGVMPRDGEDADVRWFDVEPCYVFHPMNAYEEDGTIVLDVVRN
PKMFDRDRTGPNEGPPTLDRWVIDLAAGKVRESRIDDRGQEFPRIDERLVGKRHRYGYTPTVLEGIEGGDCLLKHDLIGG
STQSRCLGPQKALGEFVFHPSSPAAAEDEGVLMGYVYDRATNRSELAILDAQTLEDVASIKLPHRVPAGFHGNWVPSTN

Sequences:

>Translated_479_residues
MANRYLQGPFAPMHHEYTLTGLEVVGTIPDYLDGRYLRNGANPIGDVDPERYHWFLGDGMVHGIRIRDGKAEWYRNRWVR
SPATSKALGQPAPPGHFGFFPIGANTNVIGHAGKTLALIEGGIANYELTEELDTVGVCDFAGTLTGGYAAHPHRDPETGE
LHAVSYNPYRGNRVQYSVIDVEGRARRTVNVTVGGSPMMHDFSLTERYVVFYDLPVTFDEAVGAAMTAPRGLRPIARLML
SALIGRVAIPDPIAARLPAATTDRRMPYSWNPNYPARVGVMPRDGEDADVRWFDVEPCYVFHPMNAYEEDGTIVLDVVRN
PKMFDRDRTGPNEGPPTLDRWVIDLAAGKVRESRIDDRGQEFPRIDERLVGKRHRYGYTPTVLEGIEGGDCLLKHDLIGG
STQSRCLGPQKALGEFVFHPSSPAAAEDEGVLMGYVYDRATNRSELAILDAQTLEDVASIKLPHRVPAGFHGNWVPSTN
>Mature_478_residues
ANRYLQGPFAPMHHEYTLTGLEVVGTIPDYLDGRYLRNGANPIGDVDPERYHWFLGDGMVHGIRIRDGKAEWYRNRWVRS
PATSKALGQPAPPGHFGFFPIGANTNVIGHAGKTLALIEGGIANYELTEELDTVGVCDFAGTLTGGYAAHPHRDPETGEL
HAVSYNPYRGNRVQYSVIDVEGRARRTVNVTVGGSPMMHDFSLTERYVVFYDLPVTFDEAVGAAMTAPRGLRPIARLMLS
ALIGRVAIPDPIAARLPAATTDRRMPYSWNPNYPARVGVMPRDGEDADVRWFDVEPCYVFHPMNAYEEDGTIVLDVVRNP
KMFDRDRTGPNEGPPTLDRWVIDLAAGKVRESRIDDRGQEFPRIDERLVGKRHRYGYTPTVLEGIEGGDCLLKHDLIGGS
TQSRCLGPQKALGEFVFHPSSPAAAEDEGVLMGYVYDRATNRSELAILDAQTLEDVASIKLPHRVPAGFHGNWVPSTN

Specific function: Cleaves a number of carotenals and carotenols in the all-trans configuration at the 15-15' double bond producing retinal or retinol, respectively. Also shows activity toward lycopenals and the corresponding alcohols. Does not cleave beta- carotene or lyco

COG id: COG3670

COG function: function code Q; Lignostilbene-alpha,beta-dioxygenase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid oxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004294 [H]

Pfam domain/function: PF03055 RPE65 [H]

EC number: =1.14.99.41 [H]

Molecular weight: Translated: 53005; Mature: 52874

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANRYLQGPFAPMHHEYTLTGLEVVGTIPDYLDGRYLRNGANPIGDVDPERYHWFLGDGM
CCCCCCCCCCCCCCCEEEEECEEEEECCHHHHCCHHHHCCCCCCCCCCCCCEEEEECCCE
VHGIRIRDGKAEWYRNRWVRSPATSKALGQPAPPGHFGFFPIGANTNVIGHAGKTLALIE
EEEEEEECCCHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEE
GGIANYELTEELDTVGVCDFAGTLTGGYAAHPHRDPETGELHAVSYNPYRGNRVQYSVID
CCCCCCCHHHHHCCCEEEHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEE
VEGRARRTVNVTVGGSPMMHDFSLTERYVVFYDLPVTFDEAVGAAMTAPRGLRPIARLML
ECCCCEEEEEEEECCCCCEEECCCCCEEEEEEECCCCHHHHHCHHHCCCCCHHHHHHHHH
SALIGRVAIPDPIAARLPAATTDRRMPYSWNPNYPARVGVMPRDGEDADVRWFDVEPCYV
HHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
FHPMNAYEEDGTIVLDVVRNPKMFDRDRTGPNEGPPTLDRWVIDLAAGKVRESRIDDRGQ
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCC
EFPRIDERLVGKRHRYGYTPTVLEGIEGGDCLLKHDLIGGSTQSRCLGPQKALGEFVFHP
CCCCHHHHHHCCHHCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHHHHEEECC
SSPAAAEDEGVLMGYVYDRATNRSELAILDAQTLEDVASIKLPHRVPAGFHGNWVPSTN
CCCCCCCCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ANRYLQGPFAPMHHEYTLTGLEVVGTIPDYLDGRYLRNGANPIGDVDPERYHWFLGDGM
CCCCCCCCCCCCCCEEEEECEEEEECCHHHHCCHHHHCCCCCCCCCCCCCEEEEECCCE
VHGIRIRDGKAEWYRNRWVRSPATSKALGQPAPPGHFGFFPIGANTNVIGHAGKTLALIE
EEEEEEECCCHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEECCCCCEEECCCCEEEEEE
GGIANYELTEELDTVGVCDFAGTLTGGYAAHPHRDPETGELHAVSYNPYRGNRVQYSVID
CCCCCCCHHHHHCCCEEEHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEEE
VEGRARRTVNVTVGGSPMMHDFSLTERYVVFYDLPVTFDEAVGAAMTAPRGLRPIARLML
ECCCCEEEEEEEECCCCCEEECCCCCEEEEEEECCCCHHHHHCHHHCCCCCHHHHHHHHH
SALIGRVAIPDPIAARLPAATTDRRMPYSWNPNYPARVGVMPRDGEDADVRWFDVEPCYV
HHHHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCEEE
FHPMNAYEEDGTIVLDVVRNPKMFDRDRTGPNEGPPTLDRWVIDLAAGKVRESRIDDRGQ
EECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCHHHHHHCCCCCC
EFPRIDERLVGKRHRYGYTPTVLEGIEGGDCLLKHDLIGGSTQSRCLGPQKALGEFVFHP
CCCCHHHHHHCCHHCCCCCHHHHHCCCCCCEEEEEECCCCCCHHHCCCHHHHHHHEEECC
SSPAAAEDEGVLMGYVYDRATNRSELAILDAQTLEDVASIKLPHRVPAGFHGNWVPSTN
CCCCCCCCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]