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The map label for this gene is clpC

Identifier: 41406559

GI number: 41406559

Start: 488298

End: 490829

Strand: Direct

Name: clpC

Synonym: MAP0461

Alternate gene names: 41406559

Gene position: 488298-490829 (Clockwise)

Preceding gene: 41406558

Following gene: 41406560

Centisome position: 10.11

GC content: 67.77

Gene sequence:

>2532_bases
ATGTTTGAACGATTTACCGACCGCGCCCGCAGGGTCGTCGTCTTGGCGCAAGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTGCTGGGTTTGATCCACGAGGGCGAGGGCGTGGCGGCCAAGTCGCTGGAGTCGCTGGGCA
TCTCGCTGGAGGGCGTCCGCAGCCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCCGGACACATCCCGTTC
ACCCCGCGCGCCAAGAAGGTGCTGGAGCTGAGCCTGCGCGAGGCGCTGCAGCTCGGCCACAACTACATCGGCACCGAGCA
CATCCTGCTGGGCCTGATCCGCGAGGGTGAGGGCGTGGCCGCCCAGGTGCTGGTCAAGCTGGGCGCCGAGCTGACCCGGG
TGCGCCAGCAGGTGATCCAGCTGCTCTCCGGCTACCAAGGCAAGGAGGCCGCCGAGGCCGGCACCGGTGGGCGCGGCGGC
GAGTCCGGCAGCCCGTCCACGTCGTTGGTGCTCGACCAGTTCGGCCGCAACCTGACCGCCGCCGCGATGGAGGGCAAGCT
GGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTGATGCAGGTGCTGAGCCGGCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGCGTCGGCAAGACGGCCGTCGTCGAGGGCCTGGCGCAGGCCATCGTGCACGGCCAGGTGCCCGAG
ACGCTGAAGGACAAGCAGCTCTACACCCTGGACCTGGGTTCGCTGGTGGCGGGCTCGCGCTACCGCGGTGACTTCGAGGA
GCGCCTGAAGAAGGTGCTCAAGGAGATCAACACCCGCGGCGACATCATCCTGTTCATCGACGAGCTGCACACGCTGGTCG
GTGCGGGTGCCGCCGAGGGCGCGATCGACGCGGCCAGCATCCTCAAGCCGAAGCTGGCCCGCGGCGAGCTGCAGACCATC
GGCGCCACCACGCTCGACGAGTACCGCAAGTACATCGAGAAGGACGCCGCCCTGGAGCGTCGGTTCCAGCCGGTGCAGGT
GGGTGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGGCTGCGCGACCGCTACGAGGCGCACCACCGGGTGTCCA
TCACCGACTCGGCGATGGTCGCGGCCGCGACGCTGGCGGACCGCTACATCAACGACCGCTACCTGCCGGACAAGGCGATC
GACCTGATCGACGAGGCGGGGGCGCGGATGCGGATCCGCCGGATGACCGCGCCGCCGGACCTGCGCGAGTTCGACGAGAA
GATCGCCGAGGCGCGCCGGGAGAAGGAATCGGCGATAGACGCCCAGGACTTCGAGAAGGCCGCCAGCCTGCGCGACCGGG
AGAAGCAGCTCGTCGCGCAGCGCGCCGAGCGCGAAAAGCAGTGGCGCTCCGGCGACCTCGACGTGGTCGCCGAGGTGGAC
GACGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGCATCCCGGTGTTCAAGCTGACCGAGGCCGAGACCACGCGCCT
GCTGCGCATGGAGGACGAGCTGCACAAGCGGATCATCGGCCAGGAGGACGCCGTCAAGGCGGTCTCCAAGGCGATCCGCC
GCACCCGCGCCGGGTTGAAGGACCCCAAGCGGCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAGCTGTCCAAGGCGCTGGCCAACTTCCTGTTCGGCGACGACGACGCGCTCATCCAGATCGACATGGGCGAGTTCCACGA
CCGGTTCACCGCCTCGCGGCTGTTCGGCGCCCCGCCGGGATACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGG
TGCGGCGCAAGCCATTCTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCTCACCAGGAGATCTACAACAGCCTGTTGCAG
GTCCTCGAGGACGGCCGGCTCACCGACGGCCAGGGCTGCACGGTCGACTTCAAGAACACCGTGCTGATCTTTACCTCGAA
CCTCGGCACGTCCGACATCTCCAAGCCGGTCGGCCTGGGCTTCACCCAGGGTGGCGGTGAGAACAACTACGAGCGGATGA
AGCAGAAGGTCAATGACGAGCTGAAGAAGCACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACTCGCGACGAGATCATCCGGATGGTCGACCTGATGATCACCCGGGTCGCCGGCCAGCTCAAGAGCAAGGACAT
GGACCTGGTGCTCACCGACAAGGCCAAGGCCCTGCTGGCCAAGCGCGGCTTCGACCCGGTGCTGGGTGCCCGCCCGCTGC
GGCGCACCATCCAGCGCGAGATCGAGGACCAGCTCTCCGAGAAGATCCTCTTCGAGGAGGTCGGGCCCGGTCAGATCGTC
ACGGTCGACGTCGACAACTGGGACGGCGAAAGCGCCGGCGAGGACGCGGTGTTCACCTTCACCGGTACCCGCAAGCCGCC
GGCCGAGCCGGACCTGGCCAAGGCCGGGGCGCACAGCGCCGACCCGCAGTAG

Upstream 100 bases:

>100_bases
GATGGCAGGTACGCGATTCCGGCCACAAGGGACCGGCAGGGTTGCCAGAAGGGCCGCTAACAGGTTTGTACCGATGGTGA
GGGAGAGCAGGTAACCACCG

Downstream 100 bases:

>100_bases
CGCATCAACGGAAAACGGGCGGTGGTCTTCCGGGACTGCCGCCCGTTTTCGCTGTGCTCTACACTGACGGCTGTCATCGA
CGTGCCACGGAATTTGGTGA

Product: ClpC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 843; Mature: 843

Protein sequence:

>843_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGCTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTRDEIIRMVDLMITRVAGQLKSKDMDLVLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQIV
TVDVDNWDGESAGEDAVFTFTGTRKPPAEPDLAKAGAHSADPQ

Sequences:

>Translated_843_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGCTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTRDEIIRMVDLMITRVAGQLKSKDMDLVLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQIV
TVDVDNWDGESAGEDAVFTFTGTRKPPAEPDLAKAGAHSADPQ
>Mature_843_residues
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGCTVDFKNTVLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTRDEIIRMVDLMITRVAGQLKSKDMDLVLTDKAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQIV
TVDVDNWDGESAGEDAVFTFTGTRKPPAEPDLAKAGAHSADPQ

Specific function: Part Of A Stress-Induced Multi-Chaperone System, It Is Involved In The Recovery Of The Cell From Heat-Induced Damage, In Cooperation With Dnak, Dnaj And Grpe. Acts Before Dnak, In The Processing Of Protein Aggregates. Protein Binding Stimulates The Atpase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=36.4548494983278, Blast_Score=194, Evalue=4e-49,
Organism=Escherichia coli, GI1788943, Length=876, Percent_Identity=45.7762557077626, Blast_Score=727, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=838, Percent_Identity=37.9474940334129, Blast_Score=514, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6320464, Length=698, Percent_Identity=47.134670487106, Blast_Score=605, Evalue=1e-174,
Organism=Saccharomyces cerevisiae, GI6323002, Length=885, Percent_Identity=36.9491525423729, Blast_Score=497, Evalue=1e-141,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 93281; Mature: 93281

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVR
CCCHHHHHCCEEEEEEHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCHHHHH
SQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEH
AAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
HHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILK
CHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAIDLIDEAGARMRIRRMTAPPD
HHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCC
LREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLK
HHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGCTVDFKNT
CCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
EEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLTRDEIIRMVDLMITRVAGQLKSKDMDLVLTDKAKALLAKRGFDPVLGARPLRRTIQRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDQLSEKILFEEVGPGQIVTVDVDNWDGESAGEDAVFTFTGTRKPPAEPDLAKAGAHSA
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHCCCCCC
DPQ
CCC
>Mature Secondary Structure
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVR
CCCHHHHHCCEEEEEEHHHHHHHHCCCCCHHHHHEEEEECCCCHHHHHHHHHCCCHHHHH
SQVEEIIGQGQQAPSGHIPFTPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHCCCCHH
AQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGGESGSPSTSLVLDQFGRNLTA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEH
AAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGQVPE
HHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCC
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEG
HHCCCEEEEEEHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCC
AIDAASILKPKLARGELQTIGATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILK
CHHHHHHHCCHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
GLRDRYEAHHRVSITDSAMVAAATLADRYINDRYLPDKAIDLIDEAGARMRIRRMTAPPD
HHHHHHHHCCEEEECHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCC
LREFDEKIAEARREKESAIDAQDFEKAASLRDREKQLVAQRAEREKQWRSGDLDVVAEVD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEDELHKRIIGQEDAVKAVSKAIRRTRAGLK
HHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
DPKRPSGSFIFAGPSGVGKTELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPG
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCC
YVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQVLEDGRLTDGQGCTVDFKNT
CCCCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCE
VLIFTSNLGTSDISKPVGLGFTQGGGENNYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
EEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QLTRDEIIRMVDLMITRVAGQLKSKDMDLVLTDKAKALLAKRGFDPVLGARPLRRTIQRE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCCCCCCHHHHHHHHHH
IEDQLSEKILFEEVGPGQIVTVDVDNWDGESAGEDAVFTFTGTRKPPAEPDLAKAGAHSA
HHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEECCCCCCCCCCHHHCCCCCC
DPQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]