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The map label for this gene is crt [H]

Identifier: 41406252

GI number: 41406252

Start: 157819

End: 158601

Strand: Direct

Name: crt [H]

Synonym: MAP0154

Alternate gene names: 41406252

Gene position: 157819-158601 (Clockwise)

Preceding gene: 41406251

Following gene: 41406253

Centisome position: 3.27

GC content: 69.6

Gene sequence:

>783_bases
ATGAACGCCAGCGCCGAACACATCCGGTATGAGAAGCGGGGCCGGATCGCCACCATCACCCTGGACCGGCCGGCCTCGCG
CAACGCGATCGATCCGGCGATGGACCGGCGGCTGCGCGACATCTGGGCCGAATTCCGCGACGACGACGGCGTCGACGTCG
CGATCCTGACCGGGGCGGGTGAGGCGTTCTGTGCCGGCGCCGACCGCAACACCTGGTTTCACCAATGGCTCGATGCCGAC
GCGGCGGTGGTGCGCCGTAACGCCAAAGGCGTTGGCTTCGGCGGCATCACCCGCGGACTGCACCGCATCACCAAGCCGGT
GATCGGGGCGGTCAACGGCTGGGCGCTGGGCGCCGGCCTGGAGCTGGCGCTGGCCTGTGACATCCGGATCGCCTCCGAGC
GGGCGATGTTCGGTGTGCCGTTGGTGGGCCTGGGTTTTCATCACGGCGACGGCGGCATCTCACGGCTGGTGGATACCTGC
GGGCTGGCCGTCGCGCTGGATCTGGAATTGAGCGGCGAACCCATCGACGCCCAACGCGCGCTGCAGGTCAACCTGGTCAC
CCGGGTGGTGGCCCACGACGACTTGATGACGGCGGCCCACGCCCTGGCCGAGCGCATTGCCGGTTATCACCAGGCCGCGG
TGCGCTCGGCCAAGGACACGGTGCTCGACGTGGTCGGGCGACCGCTGGACGAGCAACTCGAGCGGGAGGCGATGAGCGCC
TACTCCATCGATCGGCACAGCGCCCGCGAGATCATCGCCGCGGTCGGGATGCGGGGCCACTGA

Upstream 100 bases:

>100_bases
TCGAAGACAGGGCACTCGACGTCAAGCCACGCGCCCTTGTGTTAGTAGAGCGATCTATATAATCTGATGCCCGGGGGCAG
CGGATCCGAAAGGTACATCG

Downstream 100 bases:

>100_bases
TGGCCACGGCGACCCGCGAACGGTTCCTGACCGCGGCCACCGGACTCTTTCGGCGCCAAGGCTATTCGGGCACCGGCCTC
AAACAGATCGTCGCCGAGAG

Product: hypothetical protein

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFRDDDGVDVAILTGAGEAFCAGADRNTWFHQWLDAD
AAVVRRNAKGVGFGGITRGLHRITKPVIGAVNGWALGAGLELALACDIRIASERAMFGVPLVGLGFHHGDGGISRLVDTC
GLAVALDLELSGEPIDAQRALQVNLVTRVVAHDDLMTAAHALAERIAGYHQAAVRSAKDTVLDVVGRPLDEQLEREAMSA
YSIDRHSAREIIAAVGMRGH

Sequences:

>Translated_260_residues
MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFRDDDGVDVAILTGAGEAFCAGADRNTWFHQWLDAD
AAVVRRNAKGVGFGGITRGLHRITKPVIGAVNGWALGAGLELALACDIRIASERAMFGVPLVGLGFHHGDGGISRLVDTC
GLAVALDLELSGEPIDAQRALQVNLVTRVVAHDDLMTAAHALAERIAGYHQAAVRSAKDTVLDVVGRPLDEQLEREAMSA
YSIDRHSAREIIAAVGMRGH
>Mature_260_residues
MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFRDDDGVDVAILTGAGEAFCAGADRNTWFHQWLDAD
AAVVRRNAKGVGFGGITRGLHRITKPVIGAVNGWALGAGLELALACDIRIASERAMFGVPLVGLGFHHGDGGISRLVDTC
GLAVALDLELSGEPIDAQRALQVNLVTRVVAHDDLMTAAHALAERIAGYHQAAVRSAKDTVLDVVGRPLDEQLEREAMSA
YSIDRHSAREIIAAVGMRGH

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=247, Percent_Identity=34.0080971659919, Blast_Score=120, Evalue=1e-27,
Organism=Homo sapiens, GI20127408, Length=249, Percent_Identity=29.3172690763052, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI31542718, Length=233, Percent_Identity=28.755364806867, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI68989263, Length=192, Percent_Identity=32.2916666666667, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI70995211, Length=215, Percent_Identity=30.6976744186047, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1787659, Length=210, Percent_Identity=37.1428571428571, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI221142681, Length=228, Percent_Identity=34.2105263157895, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1788682, Length=194, Percent_Identity=32.4742268041237, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1788597, Length=194, Percent_Identity=35.0515463917526, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1790281, Length=197, Percent_Identity=29.9492385786802, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787660, Length=228, Percent_Identity=32.0175438596491, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082183, Length=114, Percent_Identity=31.5789473684211, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI25145438, Length=258, Percent_Identity=32.9457364341085, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17554946, Length=234, Percent_Identity=32.9059829059829, Blast_Score=107, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17560910, Length=237, Percent_Identity=29.1139240506329, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17558304, Length=218, Percent_Identity=29.8165137614679, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=207, Percent_Identity=31.4009661835749, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=230, Percent_Identity=30.4347826086957, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=212, Percent_Identity=28.3018867924528, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI25144276, Length=208, Percent_Identity=30.2884615384615, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17508951, Length=208, Percent_Identity=30.2884615384615, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=188, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508953, Length=208, Percent_Identity=30.2884615384615, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129971, Length=243, Percent_Identity=33.7448559670782, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24653477, Length=243, Percent_Identity=33.7448559670782, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21357171, Length=222, Percent_Identity=36.036036036036, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650670, Length=223, Percent_Identity=33.1838565022422, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24653139, Length=245, Percent_Identity=29.3877551020408, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24654903, Length=185, Percent_Identity=28.6486486486486, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19922422, Length=222, Percent_Identity=23.4234234234234, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583077, Length=219, Percent_Identity=29.2237442922374, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583079, Length=219, Percent_Identity=29.2237442922374, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 27997; Mature: 27997

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFRDDDGVDVAILTGAG
CCCCHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
EAFCAGADRNTWFHQWLDADAAVVRRNAKGVGFGGITRGLHRITKPVIGAVNGWALGAGL
CEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCC
ELALACDIRIASERAMFGVPLVGLGFHHGDGGISRLVDTCGLAVALDLELSGEPIDAQRA
EEEEEEEEEECCCCHHHCCCEEECEEECCCCHHHHHHHHCCEEEEEEEEECCCCCCHHHH
LQVNLVTRVVAHDDLMTAAHALAERIAGYHQAAVRSAKDTVLDVVGRPLDEQLEREAMSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YSIDRHSAREIIAAVGMRGH
HCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNASAEHIRYEKRGRIATITLDRPASRNAIDPAMDRRLRDIWAEFRDDDGVDVAILTGAG
CCCCHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCC
EAFCAGADRNTWFHQWLDADAAVVRRNAKGVGFGGITRGLHRITKPVIGAVNGWALGAGL
CEEECCCCCCHHHHHHHCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCC
ELALACDIRIASERAMFGVPLVGLGFHHGDGGISRLVDTCGLAVALDLELSGEPIDAQRA
EEEEEEEEEECCCCHHHCCCEEECEEECCCCHHHHHHHHCCEEEEEEEEECCCCCCHHHH
LQVNLVTRVVAHDDLMTAAHALAERIAGYHQAAVRSAKDTVLDVVGRPLDEQLEREAMSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
YSIDRHSAREIIAAVGMRGH
HCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]