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The map label for this gene is atpB

Identifier: 52843181

GI number: 52843181

Start: 3380540

End: 3381418

Strand: Reverse

Name: atpB

Synonym: lpg2988

Alternate gene names: 52843181

Gene position: 3381418-3380540 (Counterclockwise)

Preceding gene: 52843182

Following gene: 52843180

Centisome position: 99.52

GC content: 35.95

Gene sequence:

>879_bases
TTGCCCCATGGATTATTGTCAATAAACAGAATAGGCCAAAAAGTGACTGAAATGGTATCTAGCACAAACTATATTAAGCA
TCATTTAACGTACCTTACCTATAACGTAAATGATATGACATTCGGTTCAAGTGGTGGTTTTTGGACTTTGAACCTGGATA
CAATCTTCTTTTCTATAGCCTTGGGTCTAATTGCTCTGGCAATTATGTATTTAGCGGCAAGGAAAGTAACCACTGGTGTT
CCTGGAAAGTTACAAAATTTTGCTGAGCTCATGCTCGAGTTTGCTGATAATCAAGTTAAAGATTGTTTTCATGGAAAAAA
TAACCTAATAGGCCCATTGGCATTAACTATCTTCATGTGGGTATTCCTGATGAATTTTATGGATATCGTGCCGGTAGATA
TCCTTCCTGTACTTGCGCAGCTAGTCGGTATACACTACCTGAAAGTTGTACCAACTAATGACTTGAATTTAACATTTGGA
TTGTCACTTTCTGTATTTTTTCTAATAGTTTTTTACAGTTTAAAAATAAAAGGCGTTAAAGGTTTTGTTAAAGAGCTCAC
CCTGCAGCCCTTCAATCACCCACTATTCATTCCATTTAATTTATTGTTGGAGTTGGTTGGGCTGATAGCTAAACCCATTT
CCTTGGCATTACGACTTTTTGGTAACTTATACGCTGGCGAATTAATATTTATTTTGATAGCCTTACTAACCTTAAATGCA
ACAACGTCATCATTAATTAGTACTATGACACTGGGTACGGCGCAATTTATTCTTGCACTCGCCTGGTCCATTTTCCATAT
ATTAGTGATAACCTTACAAGCATTTATTTTTATGGTACTGACTATAGTTTATTTGAGTTTGGCCCATGAAGATCATTAA

Upstream 100 bases:

>100_bases
ATATTGTCCATGTTCCTGTTTGCATTAGTATTTTTATTATGTAGGATCACACCGGCAGCGTTTTTTGCATCATACATTTT
GGTTCTTATGACGCATTGGT

Downstream 100 bases:

>100_bases
CCGATTTAATTATCATCATCCATTGTAAAGGGGATAAAATATGCAAGCTGCTGAATTAATAGCACAAGTTCAAAGTATGA
CCGTCATTGCGGTTGCCTTG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MPHGLLSINRIGQKVTEMVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVTTGV
PGKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFG
LSLSVFFLIVFYSLKIKGVKGFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNA
TTSSLISTMTLGTAQFILALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH

Sequences:

>Translated_292_residues
MPHGLLSINRIGQKVTEMVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVTTGV
PGKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFG
LSLSVFFLIVFYSLKIKGVKGFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNA
TTSSLISTMTLGTAQFILALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH
>Mature_291_residues
PHGLLSINRIGQKVTEMVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIALGLIALAIMYLAARKVTTGVP
GKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMWVFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFGL
SLSVFFLIVFYSLKIKGVKGFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNAT
TSSLISTMTLGTAQFILALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=282, Percent_Identity=52.8368794326241, Blast_Score=282, Evalue=2e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 32530; Mature: 32399

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGLLSINRIGQKVTEMVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCCCEEEEEHHHHHHHHH
LGLIALAIMYLAARKVTTGVPGKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMW
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFGLSLSVFFLIVFYSLKIKGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNA
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TTSSLISTMTLGTAQFILALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PHGLLSINRIGQKVTEMVSSTNYIKHHLTYLTYNVNDMTFGSSGGFWTLNLDTIFFSIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCEEECCCCCEEEEEHHHHHHHHH
LGLIALAIMYLAARKVTTGVPGKLQNFAELMLEFADNQVKDCFHGKNNLIGPLALTIFMW
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
VFLMNFMDIVPVDILPVLAQLVGIHYLKVVPTNDLNLTFGLSLSVFFLIVFYSLKIKGVK
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHH
GFVKELTLQPFNHPLFIPFNLLLELVGLIAKPISLALRLFGNLYAGELIFILIALLTLNA
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TTSSLISTMTLGTAQFILALAWSIFHILVITLQAFIFMVLTIVYLSLAHEDH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA