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The map label for this gene is grlA

Identifier: 52843160

GI number: 52843160

Start: 3355541

End: 3355810

Strand: Reverse

Name: grlA

Synonym: lpg2966

Alternate gene names: 52843160

Gene position: 3355810-3355541 (Counterclockwise)

Preceding gene: 52843163

Following gene: 52843159

Centisome position: 98.77

GC content: 44.81

Gene sequence:

>270_bases
ATGCTCTACATGAAAGGCACTCCCAAGATGCCTCAATGCGGGTTTTCCGCTCGTGCAGTTCAGTGTATTGAGGCTTGTGG
AGTAGACTTTGCCTATGTCGATATCCTTGCCAATCCTGATATTCGTCAAGTTTTACCACAATTTTCTGACTGGCCTACCT
TTCCTCAACTTTATGTGAAAGGGGAATTAATTGGAGGATCTGACATCATAGCCGAAATGTTTCAGCAAGGAGAGTTAGAG
CCTATGTTGCGTGATGCAGTAGCGGCATAA

Upstream 100 bases:

>100_bases
CCTTGTTTGGTTTTCGACATAATTGGGTTTTTTATTTTATAAAAGGTGCATAGTGGATACTTTAGAAAAGATTAAAAAGC
AAATTGCTGAAAATGCGATA

Downstream 100 bases:

>100_bases
TTTTAATAACAATTGTGGGATTTACTCACCCACCGCTAATGGAGATTATAGAATGAGTGTTTTAGTTGGGCGTAAAGCAC
CTGATTTTACTGTGGCTGCA

Product: glutaredoxin-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 89

Protein sequence:

>89_residues
MLYMKGTPKMPQCGFSARAVQCIEACGVDFAYVDILANPDIRQVLPQFSDWPTFPQLYVKGELIGGSDIIAEMFQQGELE
PMLRDAVAA

Sequences:

>Translated_89_residues
MLYMKGTPKMPQCGFSARAVQCIEACGVDFAYVDILANPDIRQVLPQFSDWPTFPQLYVKGELIGGSDIIAEMFQQGELE
PMLRDAVAA
>Mature_89_residues
MLYMKGTPKMPQCGFSARAVQCIEACGVDFAYVDILANPDIRQVLPQFSDWPTFPQLYVKGELIGGSDIIAEMFQQGELE
PMLRDAVAA

Specific function: Unknown

COG id: COG0278

COG function: function code O; Glutaredoxin-related protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain

Homologues:

Organism=Homo sapiens, GI95113651, Length=84, Percent_Identity=48.8095238095238, Blast_Score=97, Evalue=2e-21,
Organism=Homo sapiens, GI42516576, Length=85, Percent_Identity=44.7058823529412, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787943, Length=88, Percent_Identity=62.5, Blast_Score=130, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71988159, Length=74, Percent_Identity=45.945945945946, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71988153, Length=74, Percent_Identity=45.945945945946, Blast_Score=82, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17556042, Length=83, Percent_Identity=39.7590361445783, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6325198, Length=91, Percent_Identity=46.1538461538462, Blast_Score=91, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6321022, Length=76, Percent_Identity=50, Blast_Score=91, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6320303, Length=76, Percent_Identity=50, Blast_Score=89, Evalue=1e-19,
Organism=Drosophila melanogaster, GI19921242, Length=84, Percent_Identity=46.4285714285714, Blast_Score=92, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24642023, Length=86, Percent_Identity=41.8604651162791, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLRXA_LEGPH (Q48833)

Other databases:

- EMBL:   L46863
- EMBL:   AE017354
- RefSeq:   YP_096959.1
- ProteinModelPortal:   Q48833
- SMR:   Q48833
- STRING:   Q48833
- GeneID:   3080034
- GenomeReviews:   AE017354_GR
- KEGG:   lpn:lpg2966
- eggNOG:   COG0278
- HOGENOM:   HBG728471
- OMA:   ILIELYQ
- ProtClustDB:   CLSK833722
- BioCyc:   LPNE272624:LPG2966-MONOMER
- InterPro:   IPR002109
- InterPro:   IPR014434
- InterPro:   IPR004480
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10
- PANTHER:   PTHR10293
- PIRSF:   PIRSF005894
- TIGRFAMs:   TIGR00365

Pfam domain/function: PF00462 Glutaredoxin; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 9844; Mature: 9844

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: PS51354 GLUTAREDOXIN_2

Important sites: BINDING 5-5 BINDING 42-42 BINDING 54-54

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
9.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYMKGTPKMPQCGFSARAVQCIEACGVDFAYVDILANPDIRQVLPQFSDWPTFPQLYVK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCCCCEEEEE
GELIGGSDIIAEMFQQGELEPMLRDAVAA
CEECCCHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MLYMKGTPKMPQCGFSARAVQCIEACGVDFAYVDILANPDIRQVLPQFSDWPTFPQLYVK
CCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHCCCCCCCCCCCEEEEE
GELIGGSDIIAEMFQQGELEPMLRDAVAA
CEECCCHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA