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The map label for this gene is macB [H]

Identifier: 52843116

GI number: 52843116

Start: 3307407

End: 3308654

Strand: Reverse

Name: macB [H]

Synonym: lpg2922

Alternate gene names: 52843116

Gene position: 3308654-3307407 (Counterclockwise)

Preceding gene: 52843117

Following gene: 52843112

Centisome position: 97.38

GC content: 45.83

Gene sequence:

>1248_bases
ATGCAAACGCCGAATAACCTTAGCCGATGGAGCAATTATAGCGGAGTCCGGGCAATGAATTTTCTTAATCATTGTCAACA
AGCCTTGGTTAATTTAACAGCCTCCAAGCTCCGATCGCTTTTGGCTGTGCTGGGAATACTGGTAGGGACCGCCGCTGTCG
TTGCCTTGATTAGCTGCGGACAACTGGCTACAGAAAAGGCGCTGGAGCAATTCAAGGCATTGGGTACCGATTTGCTGGCT
GTTTCTGTTTATCAAAAGGTGCCCAGCAAATCCCATAGTGAATCCGACTCGTTAACAATAGATCAATGGCAGCAGATAGC
TGAGCGTATACCTTATGTCTTAAGAATTGCGCCTTACAGCACGGCTTACCAAACTTTAAGTTTTAATGGCAAAGTGATGC
AAGGGGCAGTGATTGGCGCCGATGAAAGCCTTGCTGATATCATTCATGTGACCTTGGCACGGGGGCATTTTGTTTCTTTT
TTGGATTCTTTTGAGCATTTTTGTGTTATTGGCGATAGCCTGGCACAACAAATCAAAGAAATTACCCTGGATGATCCCAT
TGGCAAGCAATTACGCATAGGCCAATCCTTGTATACCATTATCGGCGTTGCCGAGCGTTGGAAAGAAAATGGTTTTTTTA
ATGAGGACATTAACCAGGCTGTCATTATTCCCCTGGCTGGAATGAGCCTGGTCAGCAAGGACGCCAAAATCAATAATGCA
GTATTGCTTCTCAAGCCGGACAGCCCCATTGATGAGGTCATTAATGAAATAAAGGAAATCATTAATTCTCAGGCGCCGAA
GCTCAGTGTTTTTCCGCGCAGCGCCAAACAAATTATAGCCAGCATGGAAAATCAGGGTCGTATTTTTACCTTGCTGTTGG
CGGTCATTGGTGGAATATCCTTGCTGGTTGGCGGCATCGGTGTCATGAATGTGATGCTGGTTTCGGTCAGCGAGCGCAAA
AAAGAAATTGGGATTCGCAAAGCAGTGGGTGCGAAAAACAGAGAAATCCAGGCCTTATTTTTGGTGGAATCTGTCATGCT
GTCTTTGCTAGGGGGTGTGCTCGGAGTCATTTTAGGTTTGATTTTTACCAGAATAGTCGCTTATTTCAGTGACTGGACTT
TTACTATCTACTTACTCCCCCCAATTGCCGGCTTTCTCGTTTCTGCTGCCACTGGAATATTTTTCGGATTTTATCCGGCC
CGACGGGCCTCGAAACTGGAGCCGATGGTTTCTTTACGCAGTGAATAG

Upstream 100 bases:

>100_bases
ATTCAAGAACAGGTAGCGAGGTAATGAATTTGTTTTTGGCCTTACACCAGGAAGGCCGGACTATTATCATGGTGACCCAT
GATGAGCACGTGGCAGCGCA

Downstream 100 bases:

>100_bases
TTTATTAGGGTCTGTTGACATTTCTACTATCTTGGCCGAAAAGCCAGCGAAATGTCAACAGACCCTAAAGTCCTACGATT
CTTTTGTATAAAACAGGATA

Product: ABC transporter, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MQTPNNLSRWSNYSGVRAMNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDLLA
VSVYQKVPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVIGADESLADIIHVTLARGHFVSF
LDSFEHFCVIGDSLAQQIKEITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNA
VLLLKPDSPIDEVINEIKEIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSERK
KEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPA
RRASKLEPMVSLRSE

Sequences:

>Translated_415_residues
MQTPNNLSRWSNYSGVRAMNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDLLA
VSVYQKVPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVIGADESLADIIHVTLARGHFVSF
LDSFEHFCVIGDSLAQQIKEITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNA
VLLLKPDSPIDEVINEIKEIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSERK
KEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPA
RRASKLEPMVSLRSE
>Mature_415_residues
MQTPNNLSRWSNYSGVRAMNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCGQLATEKALEQFKALGTDLLA
VSVYQKVPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYSTAYQTLSFNGKVMQGAVIGADESLADIIHVTLARGHFVSF
LDSFEHFCVIGDSLAQQIKEITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNA
VLLLKPDSPIDEVINEIKEIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGISLLVGGIGVMNVMLVSVSERK
KEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGLIFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPA
RRASKLEPMVSLRSE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=423, Percent_Identity=29.3144208037825, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45226; Mature: 45226

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTPNNLSRWSNYSGVRAMNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCG
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QLATEKALEQFKALGTDLLAVSVYQKVPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYS
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCH
TAYQTLSFNGKVMQGAVIGADESLADIIHVTLARGHFVSFLDSFEHFCVIGDSLAQQIKE
HHHHHHCCCCCEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCE
VLLLKPDSPIDEVINEIKEIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGIS
EEEECCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLVGGIGVMNVMLVSVSERKKEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MQTPNNLSRWSNYSGVRAMNFLNHCQQALVNLTASKLRSLLAVLGILVGTAAVVALISCG
CCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QLATEKALEQFKALGTDLLAVSVYQKVPSKSHSESDSLTIDQWQQIAERIPYVLRIAPYS
HHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCH
TAYQTLSFNGKVMQGAVIGADESLADIIHVTLARGHFVSFLDSFEHFCVIGDSLAQQIKE
HHHHHHCCCCCEEECEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ITLDDPIGKQLRIGQSLYTIIGVAERWKENGFFNEDINQAVIIPLAGMSLVSKDAKINNA
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCHHHHHCCCCCCCE
VLLLKPDSPIDEVINEIKEIINSQAPKLSVFPRSAKQIIASMENQGRIFTLLLAVIGGIS
EEEECCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LLVGGIGVMNVMLVSVSERKKEIGIRKAVGAKNREIQALFLVESVMLSLLGGVLGVILGL
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IFTRIVAYFSDWTFTIYLLPPIAGFLVSAATGIFFGFYPARRASKLEPMVSLRSE
HHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA