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The map label for this gene is orn

Identifier: 52842945

GI number: 52842945

Start: 3091385

End: 3091948

Strand: Reverse

Name: orn

Synonym: lpg2741

Alternate gene names: 52842945

Gene position: 3091948-3091385 (Counterclockwise)

Preceding gene: 161723240

Following gene: 52842944

Centisome position: 91.0

GC content: 36.88

Gene sequence:

>564_bases
ATGAAAAATAATCAAAATTTAATTTGGATTGATTTGGAAATGACTGGCCTTGAGCCAGAACAAGATAGAATTATAGAAAT
GGCCACGATTGTAACGGATCCACAACTTAACATTCTCGCAGAGGGACCTGTCATAGCGGTGTCTCAGCCTAAAATTCTTC
TAGACAGTATGGATGCATGGAATACAAAGCAACATAATCAGTCGGGATTGGTGAAGCGAGTTTTAGAGAGCAATGTCAGT
GAATCTCAAGCTGAACAATTAACGATTGAATTTTTAAAACAGTATGTGGATAAGGGAAAATCACCCATGTGTGGCAATAG
TATCTGCCAGGATAGACGTTTTTTATATAAATACATGCCTGAGTTGGCTGCTTATTTCCACTATCGGAATTTGGATGTCA
GTTCGTTGAAAGAGCTGGTATTGCGCTGGCGTCCAGAATTAATGAATGGAGTAGTTAAGGAATCGAAACATCTTGCTTTG
GATGATATAAAAGATTCAATCAATGAGCTGATTTATTATCGACAACATTTTATTAATTTGCCGGAAGTAAAAAATGACAA
ATAG

Upstream 100 bases:

>100_bases
ACTTTTATCGTACAAGGTTATGAAGGTAAAGCGATTAAGGAGGCCATGCATCAAAGTCGTGTGGCTTGTGTAGAGCGAAT
TATGACTTCTTGGAAATCAA

Downstream 100 bases:

>100_bases
AGAACGTTTAGAATTACCTAATGGCGCTAAAAAGTTATTACTTCATTCCTGTTGTGCTCCTTGTTCAGGTGAAGTGATGG
AAGCGCTCATTTTTTCTGAG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAWNTKQHNQSGLVKRVLESNVS
ESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMPELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLAL
DDIKDSINELIYYRQHFINLPEVKNDK

Sequences:

>Translated_187_residues
MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAWNTKQHNQSGLVKRVLESNVS
ESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMPELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLAL
DDIKDSINELIYYRQHFINLPEVKNDK
>Mature_187_residues
MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAWNTKQHNQSGLVKRVLESNVS
ESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMPELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLAL
DDIKDSINELIYYRQHFINLPEVKNDK

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=171, Percent_Identity=49.7076023391813, Blast_Score=175, Evalue=2e-44,
Organism=Escherichia coli, GI87082382, Length=178, Percent_Identity=64.6067415730337, Blast_Score=249, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17557752, Length=174, Percent_Identity=46.551724137931, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6323088, Length=185, Percent_Identity=35.1351351351351, Blast_Score=109, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=43.1818181818182, Blast_Score=168, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_LEGPA (Q5X1E6)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_125102.1
- ProteinModelPortal:   Q5X1E6
- SMR:   Q5X1E6
- STRING:   Q5X1E6
- GeneID:   3116413
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp2797
- LegioList:   lpp2797
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   LPNE297246:LPP2797-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21737; Mature: 21737

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: ACT_SITE 128-128

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAW
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHCCCCC
NTKQHNQSGLVKRVLESNVSESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMP
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLALDDIKDSINELIYYRQHFINL
HHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PEVKNDK
CCCCCCC
>Mature Secondary Structure
MKNNQNLIWIDLEMTGLEPEQDRIIEMATIVTDPQLNILAEGPVIAVSQPKILLDSMDAW
CCCCCCEEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEECCCEEEECCCHHHHHCCCCC
NTKQHNQSGLVKRVLESNVSESQAEQLTIEFLKQYVDKGKSPMCGNSICQDRRFLYKYMP
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
ELAAYFHYRNLDVSSLKELVLRWRPELMNGVVKESKHLALDDIKDSINELIYYRQHFINL
HHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PEVKNDK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA