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The map label for this gene is engD [H]

Identifier: 52842860

GI number: 52842860

Start: 3000301

End: 3001392

Strand: Direct

Name: engD [H]

Synonym: lpg2654

Alternate gene names: 52842860

Gene position: 3000301-3001392 (Clockwise)

Preceding gene: 52842859

Following gene: 52842861

Centisome position: 88.3

GC content: 43.96

Gene sequence:

>1092_bases
ATGGGATTTAAATGTGGAATAGTAGGATTGCCCAATGTAGGGAAATCGACTCTTTTTAATGCATTGACTAAGGCTGGGAT
AGAGGCGGCCAATTACCCATTTTGTACCATTGAGCCCAATGTAGGTATCGTCACCGTTCCTGATTCAAGACTGGATAATT
TAAGCGACATAGTCAAGCCTCAGCAGGTGCTTCATGCCACCATGCAATTTGTTGACATTGCAGGATTGGTAAAAGGCGCT
TCCAGTGGAGAAGGATTAGGAAATCAATTTTTGGCCAACATAAGAGAAACAGACGCTATTGCTCACGTCGTTCGCTGCTT
TGACAACTCGGACGTTGTTCATGTGGAGGGGCGAGTTGACCCCTTAAGTGACATAGAGGTGATTAATACAGAACTGGCAT
TAGCGGATATGGAGACATTGGAAAAGTCGCTATTAAAAGTAGGGAAAAACAGTAAAAGTGGAAATAAAGAAGCCATTTTT
GAATTAAAAACTCTGGAAAAAATTAAAGCACATCTTGATGCCGGATATCCTGTAAGAACCCTTGAACTTACCCCTGAGGA
AGAACAGGTAAGCAAACGCCTTTTTCTTTTAACGGCCAAACCAGTACTTTACATAGCCAATGTTGACGATAACGGCTATG
AGAATAACCCGCTCCTGGATAAAGTTCAGGCTCTGGCTTCCCAGGAAAATGCCAGCATAGTAGCCCTTTGTGCAGCAACA
GAAGCCGAGCTGGTTGAGCTGGATGAAGAAGACAGACAAGAGTTTATGGTTGATTTGGGGCTTAGTGAACCTGGATTAAA
TAAAGTGATCCGTGCCGGGTATGAATTGCTGGGATTGCAAACCTATTTCACCGCAGGAGTGAAAGAAGTAAGAGCCTGGA
CAATACGCAAAGGAGCCACAGCACCGCAAGCTGCCGGGGTCATTCATACTGACTTTGAGAAAGGGTTCATCCGCGCGGAA
GTGATTTCTTACGATGATTTTATTCGCTTTGGCGGAGAACAAGGTGCCAAAGAAGCTGGAAAATTGCGGCTTGAAGGCAA
GGAATATATTGTCTGTGATGGAGACGTCATGCATTTTCGCTTTAATGTTTAA

Upstream 100 bases:

>100_bases
TGCAATAGACAGAGGTATAGCGATAATACCTATAGTATTGTCAGGGGATATGGCCCGAGCAATGAATCAAGTAAACGCTT
AACATAATGAGGTATGACTC

Downstream 100 bases:

>100_bases
TCATTAGTATTCTGCAACTGGTGATTTTTCAAGAATTGAGCCAAAGAGCCTCGAGCCTCTATCGTTTCATCATTGCGAGT
GGCCAAGTATCGAGCCAGGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKPQQVLHATMQFVDIAGLVKGA
SSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIF
ELKTLEKIKAHLDAGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVQALASQENASIVALCAAT
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAE
VISYDDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV

Sequences:

>Translated_363_residues
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKPQQVLHATMQFVDIAGLVKGA
SSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIF
ELKTLEKIKAHLDAGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVQALASQENASIVALCAAT
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAE
VISYDDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV
>Mature_362_residues
GFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKPQQVLHATMQFVDIAGLVKGAS
SGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVDPLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFE
LKTLEKIKAHLDAGYPVRTLELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVQALASQENASIVALCAATE
AELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGATAPQAAGVIHTDFEKGFIRAEV
ISYDDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=45.6521739130435, Blast_Score=312, Evalue=3e-85,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=41.2844036697248, Blast_Score=164, Evalue=2e-40,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=67.7685950413223, Blast_Score=517, Evalue=1e-148,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=33.0708661417323, Blast_Score=73, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=365, Percent_Identity=44.1095890410959, Blast_Score=309, Evalue=1e-84,
Organism=Saccharomyces cerevisiae, GI6319499, Length=369, Percent_Identity=41.4634146341463, Blast_Score=268, Evalue=1e-72,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=36.5535248041775, Blast_Score=213, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6321649, Length=151, Percent_Identity=41.7218543046358, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24640873, Length=366, Percent_Identity=45.0819672131148, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640877, Length=366, Percent_Identity=45.0819672131148, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640875, Length=366, Percent_Identity=45.0819672131148, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=43.3846153846154, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24585318, Length=161, Percent_Identity=32.9192546583851, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39618; Mature: 39486

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKP
CCEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCH
QQVLHATMQFVDIAGLVKGASSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVD
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFELKTLEKIKAHLDAGYPVRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVQALASQENASIVALCAAT
EEECCCHHHHCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECC
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGAT
CHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCC
APQAAGVIHTDFEKGFIRAEVISYDDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFR
CCCCCCEEEECCCCCEEEEEEECHHHHHHCCCCCCCCHHCCEEECCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKAGIEAANYPFCTIEPNVGIVTVPDSRLDNLSDIVKP
CEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHCH
QQVLHATMQFVDIAGLVKGASSGEGLGNQFLANIRETDAIAHVVRCFDNSDVVHVEGRVD
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PLSDIEVINTELALADMETLEKSLLKVGKNSKSGNKEAIFELKTLEKIKAHLDAGYPVRT
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEE
LELTPEEEQVSKRLFLLTAKPVLYIANVDDNGYENNPLLDKVQALASQENASIVALCAAT
EEECCCHHHHCCEEEEEEECCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEEECC
EAELVELDEEDRQEFMVDLGLSEPGLNKVIRAGYELLGLQTYFTAGVKEVRAWTIRKGAT
CHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCC
APQAAGVIHTDFEKGFIRAEVISYDDFIRFGGEQGAKEAGKLRLEGKEYIVCDGDVMHFR
CCCCCCEEEECCCCCEEEEEEECHHHHHHCCCCCCCCHHCCEEECCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA