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The map label for this gene is recG

Identifier: 52842767

GI number: 52842767

Start: 2892852

End: 2894309

Strand: Direct

Name: recG

Synonym: lpg2559

Alternate gene names: 52842767

Gene position: 2892852-2894309 (Clockwise)

Preceding gene: 52842766

Following gene: 52842771

Centisome position: 85.14

GC content: 37.79

Gene sequence:

>1458_bases
ATGATAAAAAATCTAATTACACAACAAGAAGGAAAAACACTCGAGTTTAAGAGAGATTTATCATCACCAAAATCACTACT
TAAATCTATCGTTGCTTTTGCAAATACAGCTGGCGGTCACCTGATTATTGGGGTCAATGATGAAAGACAAATAATAGGTG
TTGAGCATCCATTAGACGAAGAGGAACGTCTGTGTAATCTGATTGCTGATTCTATCTCACCACGTCTTATACCTAGTATT
GAATTGGTAACACTAAATAATAAAACACTGCTGGTAATTGAAGTATTTGTCAGTAATACAGGACCTCATTGGATCAATTC
AGAAGGATCGACACAAGGTATTTATGTCCGACTAGGTTCCACAAATCGTCAAGCAGATCAAGAGCTTATCACAGAATTAC
ACCGTCGCTCAGAAGGAGTAAATTTTGATGAAATGCCCATGCCTCAGCTTTCTGTCGATGATGTTGATATAACGAAAGCT
CAAGAACTATTTTCAGATATTAAATCGCTGAATGAAAAAAACCTCCTGACTTTAAAGCTCATTACTTCTCATCAAGGAAA
ATTAGTTCCAACAAAAGGTGCGATATTGTTATTTGGAAAAGAACGCAATACATATTTTCCTGATGCCTGGGTACAATGTG
GCCGTTTCATTGGTAAAGACAAATCCCGTATTTTCGATCATGTTGATATCTATGACTATCTTCCCGATGCAGTTGAGAGC
ATCATGATGTTTTTGAAAAAGCACGCTTTACGTGGCGCTGATTTTTCAGCAGTACAAAGAAAAGATATTTGGAGTATCCC
TCTTGTTATGTTGCGCGAAGCTGTTATCAATGCACTTGTCCATACCGACTACTCTCAACGTGGTGCGCCAATTAGGATCT
CTTTTTTTGACGACCGTATAGAAATAGAAAACCCAGGAATCCTGTTACCTGGGCTAACGATTGAAGATATGCGACAAGGC
ATATCCAAAATTAGAAATCATGTTATTGCCAGAGTTTTCCGTGAACTTAATTTAATCGAACAATGGGGAAGTGGTGTAAG
TCGTATCTATTCCGAAGCTATAGAACAAAAATTACAAGAACCAGAAATTATAGAAATTGGGATGCGAATACGCTTTATTA
TATATCTTGCACAAGGGATACCAATCGATTCCACTTTCGATAAAAGGGATAAACAATTGGAGTCACGGCTAGAGTCACGG
CTAGAGTCACGGCTAGAGTCAAAACTTGCGGCTAGAGTCATCCAAGTACTGCAAAATGGGGAAGCTGGAAAAATACAAAT
TGCTCGAAGTTTAGGTCATCAAACAGTATCAGGAGAACTACACAAGCAAATTAAGCAGCTACTAAAGCTTGAGATAATAG
AAATGACTATTCCAGATAAACCAAATAGTAGATTGCAAAAGTATCGCCTGACTAACAAAGGGATAGATCTAATAAACATC
ATACAGCGGGAATTGTAA

Upstream 100 bases:

>100_bases
AGAACGTATTAAGCAACTTATAGGATCAGACTCCCTCAAATTAGCTGTATATTGCAAAACTGCTTTAAACAAAGCAGAAA
TTACAATTGGATAAAAATTC

Downstream 100 bases:

>100_bases
TGCTCACCCTAGGTTTTTCTCAAGGCCAAAATAATAAAAATCAGACAAAACCTCTTCACTTATCAATAACAGATTAGTAT
TTGTCTGATTTTAAAAAAGC

Product: ATP-dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MIKNLITQQEGKTLEFKRDLSSPKSLLKSIVAFANTAGGHLIIGVNDERQIIGVEHPLDEEERLCNLIADSISPRLIPSI
ELVTLNNKTLLVIEVFVSNTGPHWINSEGSTQGIYVRLGSTNRQADQELITELHRRSEGVNFDEMPMPQLSVDDVDITKA
QELFSDIKSLNEKNLLTLKLITSHQGKLVPTKGAILLFGKERNTYFPDAWVQCGRFIGKDKSRIFDHVDIYDYLPDAVES
IMMFLKKHALRGADFSAVQRKDIWSIPLVMLREAVINALVHTDYSQRGAPIRISFFDDRIEIENPGILLPGLTIEDMRQG
ISKIRNHVIARVFRELNLIEQWGSGVSRIYSEAIEQKLQEPEIIEIGMRIRFIIYLAQGIPIDSTFDKRDKQLESRLESR
LESRLESKLAARVIQVLQNGEAGKIQIARSLGHQTVSGELHKQIKQLLKLEIIEMTIPDKPNSRLQKYRLTNKGIDLINI
IQREL

Sequences:

>Translated_485_residues
MIKNLITQQEGKTLEFKRDLSSPKSLLKSIVAFANTAGGHLIIGVNDERQIIGVEHPLDEEERLCNLIADSISPRLIPSI
ELVTLNNKTLLVIEVFVSNTGPHWINSEGSTQGIYVRLGSTNRQADQELITELHRRSEGVNFDEMPMPQLSVDDVDITKA
QELFSDIKSLNEKNLLTLKLITSHQGKLVPTKGAILLFGKERNTYFPDAWVQCGRFIGKDKSRIFDHVDIYDYLPDAVES
IMMFLKKHALRGADFSAVQRKDIWSIPLVMLREAVINALVHTDYSQRGAPIRISFFDDRIEIENPGILLPGLTIEDMRQG
ISKIRNHVIARVFRELNLIEQWGSGVSRIYSEAIEQKLQEPEIIEIGMRIRFIIYLAQGIPIDSTFDKRDKQLESRLESR
LESRLESKLAARVIQVLQNGEAGKIQIARSLGHQTVSGELHKQIKQLLKLEIIEMTIPDKPNSRLQKYRLTNKGIDLINI
IQREL
>Mature_485_residues
MIKNLITQQEGKTLEFKRDLSSPKSLLKSIVAFANTAGGHLIIGVNDERQIIGVEHPLDEEERLCNLIADSISPRLIPSI
ELVTLNNKTLLVIEVFVSNTGPHWINSEGSTQGIYVRLGSTNRQADQELITELHRRSEGVNFDEMPMPQLSVDDVDITKA
QELFSDIKSLNEKNLLTLKLITSHQGKLVPTKGAILLFGKERNTYFPDAWVQCGRFIGKDKSRIFDHVDIYDYLPDAVES
IMMFLKKHALRGADFSAVQRKDIWSIPLVMLREAVINALVHTDYSQRGAPIRISFFDDRIEIENPGILLPGLTIEDMRQG
ISKIRNHVIARVFRELNLIEQWGSGVSRIYSEAIEQKLQEPEIIEIGMRIRFIIYLAQGIPIDSTFDKRDKQLESRLESR
LESRLESKLAARVIQVLQNGEAGKIQIARSLGHQTVSGELHKQIKQLLKLEIIEMTIPDKPNSRLQKYRLTNKGIDLINI
IQREL

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG2865

COG function: function code K; Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 55162; Mature: 55162

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNLITQQEGKTLEFKRDLSSPKSLLKSIVAFANTAGGHLIIGVNDERQIIGVEHPLDE
CCCCHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCH
EERLCNLIADSISPRLIPSIELVTLNNKTLLVIEVFVSNTGPHWINSEGSTQGIYVRLGS
HHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCEECCCCCCCEEEEEECC
TNRQADQELITELHRRSEGVNFDEMPMPQLSVDDVDITKAQELFSDIKSLNEKNLLTLKL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
ITSHQGKLVPTKGAILLFGKERNTYFPDAWVQCGRFIGKDKSRIFDHVDIYDYLPDAVES
EECCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IMMFLKKHALRGADFSAVQRKDIWSIPLVMLREAVINALVHTDYSQRGAPIRISFFDDRI
HHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCEE
EIENPGILLPGLTIEDMRQGISKIRNHVIARVFRELNLIEQWGSGVSRIYSEAIEQKLQE
EECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PEIIEIGMRIRFIIYLAQGIPIDSTFDKRDKQLESRLESRLESRLESKLAARVIQVLQNG
CCEEHHHHHHEEEEEHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EAGKIQIARSLGHQTVSGELHKQIKQLLKLEIIEMTIPDKPNSRLQKYRLTNKGIDLINI
CCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCCHHHHH
IQREL
HHHCC
>Mature Secondary Structure
MIKNLITQQEGKTLEFKRDLSSPKSLLKSIVAFANTAGGHLIIGVNDERQIIGVEHPLDE
CCCCHHCCCCCCEEHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEECCCCCCH
EERLCNLIADSISPRLIPSIELVTLNNKTLLVIEVFVSNTGPHWINSEGSTQGIYVRLGS
HHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEEEEECCCCCCEECCCCCCCEEEEEECC
TNRQADQELITELHRRSEGVNFDEMPMPQLSVDDVDITKAQELFSDIKSLNEKNLLTLKL
CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
ITSHQGKLVPTKGAILLFGKERNTYFPDAWVQCGRFIGKDKSRIFDHVDIYDYLPDAVES
EECCCCCEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
IMMFLKKHALRGADFSAVQRKDIWSIPLVMLREAVINALVHTDYSQRGAPIRISFFDDRI
HHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCEE
EIENPGILLPGLTIEDMRQGISKIRNHVIARVFRELNLIEQWGSGVSRIYSEAIEQKLQE
EECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
PEIIEIGMRIRFIIYLAQGIPIDSTFDKRDKQLESRLESRLESRLESKLAARVIQVLQNG
CCEEHHHHHHEEEEEHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EAGKIQIARSLGHQTVSGELHKQIKQLLKLEIIEMTIPDKPNSRLQKYRLTNKGIDLINI
CCCEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCCHHHHH
IQREL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9603897 [H]