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The map label for this gene is kup

Identifier: 52842593

GI number: 52842593

Start: 2690122

End: 2692047

Strand: Direct

Name: kup

Synonym: lpg2384

Alternate gene names: 52842593

Gene position: 2690122-2692047 (Clockwise)

Preceding gene: 52842592

Following gene: 52842594

Centisome position: 79.17

GC content: 41.12

Gene sequence:

>1926_bases
TTGAGCAAAGATAAATTTAATGAGAGAGCCAACTCAATGCCCTCAACAAGAAACATTGAAACGCATAACGACTCCAATCC
CACATTGCGAGCACTAAGCCTATCAGCCTTGGGCATAGTTTACGGAGATATTGGAACGAGCCCTCTTTATACTTTTAAGA
CGGTGATATTGCTGGCTGGAGGGGGAACTCCAGCCGTAAACACCATTATGGGTTCGGTATCATTGATTATATGGACTCTG
ATAATCATCGCATCTGTTAAATACATCCACTTTGCTTTACGGATTGACAACGATGGTGAGGGAGGGATTCTCGCGCTAAT
GTCCCTTTTGAGTTTAAAACTGAAGCAAAGGCCTTTCATTATCGCAGTTGGACTTATGGGGGCTGCTCTTATCTATGGAG
ATGGCACAATTACCCCAGCCATATCGGTGCTCTCTGCTGTAGAGGGACTTGAAATCCTTTCCCCATCACTTAAGTATTAT
GTTTTGCCTATTGCGATAACAATTCTGATAACACTTTTTGCGATTCAATCTAAAGGTACCGCAACTATTGGAAAGGCCTT
TGGCCCAGTGATGGCATTTTGGTTTTTAACCATTGGTATTTTAGGGGCAAGAGGAGTTATCCAACACCCTTCTGTATTAG
CGGCGATTAATCCCATCTATGGCCTAAGTTTTTTATTTTCAAATGGCGCCACAGGATTTTTTATTCTATGTGGGGTCTTT
CTTTGCGTCACTGGTGCAGAGGCTTTATACGCCGACCTGGGACATTTTGGTACCGCCCCAATTCGCTGCGCCTGGTTTGG
TCTGGCTTTTCCAAGCCTTATCTTTAACTATCTGGGACAAGCCGCTTTGGTTTTGGAAGGAGCATCCACGGAGCATAATA
TTTTTTATATGCTGTGCCCGGGTGATTTTTTATTACCGTTAATAATTCTGTCCACCGTCGCAACAATTATTGCCAGCCAA
GCCATTATTACCGGAGCATTTTCCATGACAAGACAAGCAATGCAACTGGGTTGGCTGCCCAGATTACGAGTCACGCAAAC
GTCTTCAGAAGGTTATGGGCAAATTTATATAGGAGTCGTTAACTGGCTTTTAATGCTGGCTACCCTTGGGCTTACTATTG
GATTTGGCAGTTCTGAAAAATTAGCCGCTGCCTATGGCATTGCTGTTTCAGCTACTATGCTTTGCACCACTCTGCTTTTA
TTTATTGCTCTGCATAAACTATGGAAATGGGATATTATCACATCAGGGCTTGTTGCTGGATTATTCATGATTGTCGATGC
CTCTTTTTTTGCGGCTAATCTCACGAAATTCATCAATGGCGGATATATACCAATCACATTGGCAATCATAATCTATTCCA
TGATGTATATTTGGCATAAAGGCTATCAAACCATCGCAATCAAGCAAAAAGAAAAAAATATAACAGTCGCTTCCTTTCTG
GACAGTATTCAAAAAGAGAGGGTAGTCCGTGTGCCTAAAACTGCTGTTTTTCTTACATCCAAAGAGCAGGATATTCCTCC
AATCCTGGTTTGGCATGTCAAGAAAAATCATGTGTTGCAGGATAAGGTGATTATTTTAAAAATTAACAACTTGTCCATTC
CCCGGTGTAAACCTGGTGATCGATTACAAATTGTAGAAACAGGAACAGGCATCTGGCATGCCGTAGCAAATTATGGCTTT
ATGGAACAACCTCATATTCCAAAATTATTAAAGAAATTAGAGGCTCAAGGCTATGACATCAATATCAAAGACATAACCTA
TTATATCGGTCATGAAACAATATTTGTCCGCAATGTCCGTCATACTCTGTCAAAATACATTAAAATTCTCTTCGTTTTTA
TGCATCGCAATGCCCTTCCCATGAGTAACTACTTTCATCTTCCGCCAGAATCAGTATTTGAAATAGGACGACAGATAGAA
ATTTAG

Upstream 100 bases:

>100_bases
GATGGATCAGTAATTTAATCTATTTTCTATTGCAAATTCAAAGAATTAGATTAATTTATCTAAGATTAAAGTGGCACTTA
TTGGAGGATAACCCCTCCTT

Downstream 100 bases:

>100_bases
TGAAAATAATTGATCCCACACATGGAAAACTCTGTGGGTGAGTGCTGTTTTATGGTCAGGATTGAATTTTGCACCTGGTC
TTATAGCACATATGACAAAT

Product: Kup system potassium uptake protein

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 640

Protein sequence:

>641_residues
MSKDKFNERANSMPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPAVNTIMGSVSLIIWTL
IIIASVKYIHFALRIDNDGEGGILALMSLLSLKLKQRPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYY
VLPIAITILITLFAIQSKGTATIGKAFGPVMAFWFLTIGILGARGVIQHPSVLAAINPIYGLSFLFSNGATGFFILCGVF
LCVTGAEALYADLGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPGDFLLPLIILSTVATIIASQ
AIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLTIGFGSSEKLAAAYGIAVSATMLCTTLLL
FIALHKLWKWDIITSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYQTIAIKQKEKNITVASFL
DSIQKERVVRVPKTAVFLTSKEQDIPPILVWHVKKNHVLQDKVIILKINNLSIPRCKPGDRLQIVETGTGIWHAVANYGF
MEQPHIPKLLKKLEAQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIE
I

Sequences:

>Translated_641_residues
MSKDKFNERANSMPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPAVNTIMGSVSLIIWTL
IIIASVKYIHFALRIDNDGEGGILALMSLLSLKLKQRPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYY
VLPIAITILITLFAIQSKGTATIGKAFGPVMAFWFLTIGILGARGVIQHPSVLAAINPIYGLSFLFSNGATGFFILCGVF
LCVTGAEALYADLGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPGDFLLPLIILSTVATIIASQ
AIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLTIGFGSSEKLAAAYGIAVSATMLCTTLLL
FIALHKLWKWDIITSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYQTIAIKQKEKNITVASFL
DSIQKERVVRVPKTAVFLTSKEQDIPPILVWHVKKNHVLQDKVIILKINNLSIPRCKPGDRLQIVETGTGIWHAVANYGF
MEQPHIPKLLKKLEAQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIE
I
>Mature_640_residues
SKDKFNERANSMPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAGGGTPAVNTIMGSVSLIIWTLI
IIASVKYIHFALRIDNDGEGGILALMSLLSLKLKQRPFIIAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYV
LPIAITILITLFAIQSKGTATIGKAFGPVMAFWFLTIGILGARGVIQHPSVLAAINPIYGLSFLFSNGATGFFILCGVFL
CVTGAEALYADLGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCPGDFLLPLIILSTVATIIASQA
IITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVVNWLLMLATLGLTIGFGSSEKLAAAYGIAVSATMLCTTLLLF
IALHKLWKWDIITSGLVAGLFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYQTIAIKQKEKNITVASFLD
SIQKERVVRVPKTAVFLTSKEQDIPPILVWHVKKNHVLQDKVIILKINNLSIPRCKPGDRLQIVETGTGIWHAVANYGFM
EQPHIPKLLKKLEAQGYDINIKDITYYIGHETIFVRNVRHTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI

Specific function: Transport of potassium into the cell [H]

COG id: COG3158

COG function: function code P; K+ transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAK/KUP transporter (TC 2.A.72) family [H]

Homologues:

Organism=Escherichia coli, GI48994960, Length=621, Percent_Identity=39.6135265700483, Blast_Score=479, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003855
- InterPro:   IPR023051 [H]

Pfam domain/function: PF02705 K_trans [H]

EC number: NA

Molecular weight: Translated: 70277; Mature: 70146

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDKFNERANSMPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAG
CCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHEEEEECCCCCCHHHEEEEEEEEC
GGTPAVNTIMGSVSLIIWTLIIIASVKYIHFALRIDNDGEGGILALMSLLSLKLKQRPFI
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEE
IAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITLFAIQSKGT
EEEEHHHCEEEECCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
ATIGKAFGPVMAFWFLTIGILGARGVIQHPSVLAAINPIYGLSFLFSNGATGFFILCGVF
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHHHHHCCCCCHHHHHHHHH
LCVTGAEALYADLGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCP
HHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECC
GDFLLPLIILSTVATIIASQAIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHH
NWLLMLATLGLTIGFGSSEKLAAAYGIAVSATMLCTTLLLFIALHKLWKWDIITSGLVAG
HHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYQTIAIKQKEKNITVASFL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
DSIQKERVVRVPKTAVFLTSKEQDIPPILVWHVKKNHVLQDKVIILKINNLSIPRCKPGD
HHHHHHHEEECCCEEEEEECCCCCCCCEEEEEECCCCEEECEEEEEEECCCCCCCCCCCC
RLQIVETGTGIWHAVANYGFMEQPHIPKLLKKLEAQGYDINIKDITYYIGHETIFVRNVR
CEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCEEEEHHHH
HTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI
HHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHCCCCCC
>Mature Secondary Structure 
SKDKFNERANSMPSTRNIETHNDSNPTLRALSLSALGIVYGDIGTSPLYTFKTVILLAG
CCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEHHHHEEEEECCCCCCHHHEEEEEEEEC
GGTPAVNTIMGSVSLIIWTLIIIASVKYIHFALRIDNDGEGGILALMSLLSLKLKQRPFI
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCEE
IAVGLMGAALIYGDGTITPAISVLSAVEGLEILSPSLKYYVLPIAITILITLFAIQSKGT
EEEEHHHCEEEECCCCHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCC
ATIGKAFGPVMAFWFLTIGILGARGVIQHPSVLAAINPIYGLSFLFSNGATGFFILCGVF
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHHHHHCCCCCHHHHHHHHH
LCVTGAEALYADLGHFGTAPIRCAWFGLAFPSLIFNYLGQAALVLEGASTEHNIFYMLCP
HHHHCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEECC
GDFLLPLIILSTVATIIASQAIITGAFSMTRQAMQLGWLPRLRVTQTSSEGYGQIYIGVV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHH
NWLLMLATLGLTIGFGSSEKLAAAYGIAVSATMLCTTLLLFIALHKLWKWDIITSGLVAG
HHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFMIVDASFFAANLTKFINGGYIPITLAIIIYSMMYIWHKGYQTIAIKQKEKNITVASFL
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHH
DSIQKERVVRVPKTAVFLTSKEQDIPPILVWHVKKNHVLQDKVIILKINNLSIPRCKPGD
HHHHHHHEEECCCEEEEEECCCCCCCCEEEEEECCCCEEECEEEEEEECCCCCCCCCCCC
RLQIVETGTGIWHAVANYGFMEQPHIPKLLKKLEAQGYDINIKDITYYIGHETIFVRNVR
CEEEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEECCCEEEEHHHH
HTLSKYIKILFVFMHRNALPMSNYFHLPPESVFEIGRQIEI
HHHHHHHHHHHHHHHCCCCCCCCEECCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA