Click here to switch to the map view.

The map label for this gene is motA

Identifier: 52842528

GI number: 52842528

Start: 2619875

End: 2620780

Strand: Direct

Name: motA

Synonym: lpg2318

Alternate gene names: 52842528

Gene position: 2619875-2620780 (Clockwise)

Preceding gene: 52842527

Following gene: 52842529

Centisome position: 77.11

GC content: 39.18

Gene sequence:

>906_bases
ATGTTAATTATAGTAGGTTATATTGTAATACTACTCTGTGTATTTGGTGGATTCAGCCTGACAGGCGGCCATCTCGCCGC
AATATTTCAGCCTGTTGAATTATTGATAATCGGAGGGGCCGCCATGGGTTCCTTTATCGTTGGTAATAATATTACCGTTT
TAAAATCTGTTCTAAAATCTCTGCCTGCTACATTTCGCGGCCAAAAATCGGCAAAGCAAGCCTCCAATGATTTGTTAAGC
CTTCTATACCATTTACTCAGTAAAGCAAGGCAACAAGGGTTAATGTCGCTCGAAAATGACATTGACGAGCCGGATAAAAG
CCCAATTTTTACCGGTTATCCCAATTTAATGAGTAATCATCATTTAATAGAGTTTATTTGTGATTACCTGAGATTGATTA
TCACTTCCAACATGCAGCCTTTTCAATTGGAAAGCTTGATGGATATGGAGATCGAATCTCACCATGAAGAAGAAATGATC
CCAGCCAATGCCATCACCAAACTGGCTGATGCCATGCCTGCTTTTGGTATCGTTGCAGCAGTATTAGGTGTTGTCCATAC
CATGGAATCCATCAGCTTACCTCCCTCTGAATTAGGTGTTTTAATCGCTCACGCGTTAGTGGGAACCTTTTTAGGTATTT
TAATTGGCTATGGTTTTGTTGGGCCTATCGCTACTGCTATGGAACAAAATGCCAATCAAAATCAATTGATGCTGCAATGT
ATAAAAGTTACCATACTGGCAAGTTTGCACAATAACCCTCCTATTATTGCTACTGAATTTGGCCGTAAAGTATTATTTAC
ATCGCAAAGACCTTCATTTAATCAATTAAATGATGAAATAAAAAATGCCAAAACCGCTCAGACAACAACTCAAAACTCTG
AAGCAACAGAAGCTACATCCAGTTAG

Upstream 100 bases:

>100_bases
TCCCAATGACTGAAGGTATAGCACTGTATGACATGTCTGCCAAAGACACTATGAAAAAATATCAAGACTAATTGGACACT
AGATACTATAGGATAGGGAT

Downstream 100 bases:

>100_bases
GTTACAGCCATGAGCGAAATAAACGACATCAGCGATCCGATCAACGACGATCTGGAAAAAAAGGACAAGCGGGAAAAAAA
AGAAAAAACCACTCACTATA

Product: flagellar motor protein MotA

Products: NA

Alternate protein names: Chemotaxis protein MotA [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAMGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASNDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTGYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATSS

Sequences:

>Translated_301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAMGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASNDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTGYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATSS
>Mature_301_residues
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAMGSFIVGNNITVLKSVLKSLPATFRGQKSAKQASNDLLS
LLYHLLSKARQQGLMSLENDIDEPDKSPIFTGYPNLMSNHHLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMI
PANAITKLADAMPAFGIVAAVLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATSS

Specific function: MotA and MotB comprise the stator element of the flagellar motor complex. Required for rotation of the flagellar motor. Probable transmembrane proton channel. Overexpression of MotA, with or without MotB, restores motility in a yhjH disruption, (a c-di-GM

COG id: COG1291

COG function: function code N; Flagellar motor component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MotA family [H]

Homologues:

Organism=Escherichia coli, GI1788199, Length=295, Percent_Identity=51.864406779661, Blast_Score=333, Evalue=8e-93,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000540
- InterPro:   IPR022522
- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 32577; Mature: 32577

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS01307 MOTA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAMGSFIVGNNITVLKSVLKS
CEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCHHHCCHHCCCCHHHHHHHHHH
LPATFRGQKSAKQASNDLLSLLYHLLSKARQQGLMSLENDIDEPDKSPIFTGYPNLMSNH
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
HLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMIPANAITKLADAMPAFGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCHHHHHHH
VLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATS
HHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCHHCCC
S
C
>Mature Secondary Structure
MLIIVGYIVILLCVFGGFSLTGGHLAAIFQPVELLIIGGAAMGSFIVGNNITVLKSVLKS
CEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCHHHCCHHCCCCHHHHHHHHHH
LPATFRGQKSAKQASNDLLSLLYHLLSKARQQGLMSLENDIDEPDKSPIFTGYPNLMSNH
CCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCC
HLIEFICDYLRLIITSNMQPFQLESLMDMEIESHHEEEMIPANAITKLADAMPAFGIVAA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHCCHHHHHHH
VLGVVHTMESISLPPSELGVLIAHALVGTFLGILIGYGFVGPIATAMEQNANQNQLMLQC
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
IKVTILASLHNNPPIIATEFGRKVLFTSQRPSFNQLNDEIKNAKTAQTTTQNSEATEATS
HHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHCCHHHHHCCCCCCCHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 6090403; 9097040; 9278503; 3007435; 1719217; 7643400 [H]