| Definition | Legionella pneumophila subsp. pneumophila str. Philadelphia 1 chromosome, complete genome. |
|---|---|
| Accession | NC_002942 |
| Length | 3,397,754 |
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The map label for this gene is bdhA
Identifier: 52842526
GI number: 52842526
Start: 2617896
End: 2618678
Strand: Direct
Name: bdhA
Synonym: lpg2316
Alternate gene names: 52842526
Gene position: 2617896-2618678 (Clockwise)
Preceding gene: 52842525
Following gene: 52842527
Centisome position: 77.05
GC content: 42.4
Gene sequence:
>783_bases ATGAAACTGAAGAATAAAGTCGCTATTGTTACAGGAGCAGCAAGCGGAATTGGTAAAGAAATTGCGCTTGTTTATGCTAA AGAAGGGGCAAAGGTAGCAATCGCTGATCTGAATCTTGATCAGGCAAGCCATGTAGCAGAGGAAATCAAATCATCAGGCG GACAAGCAATGGCCGTTGCCATGAATGTAACTGATGAAGCACAAGTCAATCAGGGCGTGGATAAAGTAGCCGATCACTTT GGAGGGGTTGATGTTTTAGTCAGCAATGCCGGTATTCAAATCATCGAATCAGTGGATAAATTAGCCTTTTCAGACTGGAA AAGAATGCTTGCCATTCATTTGGATGGTGCCTTTTTAACTACTAAAGCTTGCTTGAAATACATGTATGCCTCAGGCAATG GCGGCAGTATTATTTATATGGGCTCGGTCCATTCCAAAGAAGCTTCTGTACTCAAAGCACCTTATGTTACTGCCAAACAT GGTCTATTGGGTTTATGCAAAGTAGTTGCCAAGGAAGGTGGAACTCATAAGGTAAGAGCCAATGTCATTTGCCCGGGGTT TGTCCGTACTCCTCTCGTTGACAAACAAATTCCAGAGCAAGCAAAAGAATTAGGCATCAGTGAAGAAGATGTCATCAAGA AAGTGATGCTAAAAGAAACAGTTGACGGGGAATTCACCACCACAGACGATGTAGCACAAACCGCTTTATTTTTTGCATCA TTTGAATCGAATGCGCTTACAGGACAATCATTGGTAGTCAGTCATGGTTGGTTCATGGAGTAA
Upstream 100 bases:
>100_bases AAACAATTCATCAAAGATTTTTGTTAGCAAATAATAAGGCATTATTAAAAATCCATTGCTATAATCAATTCATGGAAAAC AATGACAAGGATAGTAAAAG
Downstream 100 bases:
>100_bases ACAACCATGACTCGAACTAAAAAATCTGCAAGACAGATTGAGTATCGCCATATTGCATGCAGCTTTCAGGGAGGAGGGGC TTTGGGTGCCTATCAAGCTG
Product: 3-hydroxybutyrate dehydrogenase
Products: NA
Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]
Number of amino acids: Translated: 260; Mature: 260
Protein sequence:
>260_residues MKLKNKVAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVAMNVTDEAQVNQGVDKVADHF GGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLTTKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKH GLLGLCKVVAKEGGTHKVRANVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS FESNALTGQSLVVSHGWFME
Sequences:
>Translated_260_residues MKLKNKVAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVAMNVTDEAQVNQGVDKVADHF GGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLTTKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKH GLLGLCKVVAKEGGTHKVRANVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS FESNALTGQSLVVSHGWFME >Mature_260_residues MKLKNKVAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVAMNVTDEAQVNQGVDKVADHF GGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLTTKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKH GLLGLCKVVAKEGGTHKVRANVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS FESNALTGQSLVVSHGWFME
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=267, Percent_Identity=31.8352059925094, Blast_Score=123, Evalue=2e-28, Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=31.2252964426877, Blast_Score=105, Evalue=3e-23, Organism=Homo sapiens, GI31542939, Length=222, Percent_Identity=32.8828828828829, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=34.2412451361868, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=34.5360824742268, Blast_Score=99, Evalue=3e-21, Organism=Homo sapiens, GI32483357, Length=261, Percent_Identity=29.8850574712644, Blast_Score=93, Evalue=3e-19, Organism=Homo sapiens, GI19923817, Length=259, Percent_Identity=26.6409266409266, Blast_Score=86, Evalue=4e-17, Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=9e-17, Organism=Homo sapiens, GI5031737, Length=189, Percent_Identity=29.6296296296296, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=29.6296296296296, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI40254986, Length=141, Percent_Identity=36.1702127659575, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=24.4186046511628, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI209862901, Length=267, Percent_Identity=28.8389513108614, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI19923983, Length=267, Percent_Identity=28.8389513108614, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI20149619, Length=210, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI157739938, Length=203, Percent_Identity=26.1083743842365, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=27.0386266094421, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI4503301, Length=239, Percent_Identity=25.9414225941423, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI210032110, Length=190, Percent_Identity=25.7894736842105, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI7705925, Length=257, Percent_Identity=26.0700389105058, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4758504, Length=209, Percent_Identity=29.1866028708134, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI142976729, Length=216, Percent_Identity=24.537037037037, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI126723191, Length=199, Percent_Identity=27.6381909547739, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI126723750, Length=264, Percent_Identity=26.5151515151515, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI7706318, Length=201, Percent_Identity=23.8805970149254, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=31.7647058823529, Blast_Score=123, Evalue=9e-30, Organism=Escherichia coli, GI1787335, Length=259, Percent_Identity=30.1158301158301, Blast_Score=118, Evalue=5e-28, Organism=Escherichia coli, GI1787905, Length=261, Percent_Identity=31.8007662835249, Blast_Score=114, Evalue=8e-27, Organism=Escherichia coli, GI1789057, Length=265, Percent_Identity=32.0754716981132, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI1789208, Length=260, Percent_Identity=26.9230769230769, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=31.6602316602317, Blast_Score=112, Evalue=4e-26, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=29.3893129770992, Blast_Score=101, Evalue=5e-23, Organism=Escherichia coli, GI1790717, Length=256, Percent_Identity=25.78125, Blast_Score=100, Evalue=1e-22, Organism=Escherichia coli, GI1789378, Length=194, Percent_Identity=29.3814432989691, Blast_Score=83, Evalue=1e-17, Organism=Escherichia coli, GI2367175, Length=198, Percent_Identity=31.3131313131313, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1786812, Length=262, Percent_Identity=28.6259541984733, Blast_Score=78, Evalue=5e-16, Organism=Escherichia coli, GI1787526, Length=217, Percent_Identity=24.8847926267281, Blast_Score=72, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=28.4046692607004, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17568967, Length=195, Percent_Identity=36.4102564102564, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=29.8449612403101, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=29.8387096774194, Blast_Score=92, Evalue=3e-19, Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=31.9587628865979, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193203117, Length=232, Percent_Identity=27.5862068965517, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI193203115, Length=230, Percent_Identity=27.3913043478261, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=29.2307692307692, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=28.6458333333333, Blast_Score=84, Evalue=7e-17, Organism=Caenorhabditis elegans, GI17538182, Length=212, Percent_Identity=32.5471698113208, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=23.921568627451, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=26.6129032258064, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562910, Length=270, Percent_Identity=25.5555555555556, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17561272, Length=190, Percent_Identity=32.1052631578947, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=27.1375464684015, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17567345, Length=194, Percent_Identity=25.2577319587629, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI17558628, Length=130, Percent_Identity=37.6923076923077, Blast_Score=74, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17563726, Length=268, Percent_Identity=26.1194029850746, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=26.8382352941176, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17562904, Length=211, Percent_Identity=27.9620853080569, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=27.4436090225564, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71994604, Length=254, Percent_Identity=24.8031496062992, Blast_Score=72, Evalue=3e-13, Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=24.3542435424354, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17507613, Length=203, Percent_Identity=27.0935960591133, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI32563809, Length=201, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17551412, Length=220, Percent_Identity=25.4545454545455, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=24.4444444444444, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=25.5725190839695, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI115534660, Length=235, Percent_Identity=26.8085106382979, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI17562906, Length=197, Percent_Identity=27.9187817258883, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17508651, Length=254, Percent_Identity=26.7716535433071, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562908, Length=269, Percent_Identity=27.5092936802974, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17538486, Length=197, Percent_Identity=26.3959390862944, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17562990, Length=266, Percent_Identity=25.187969924812, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17560150, Length=269, Percent_Identity=25.6505576208178, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17538480, Length=197, Percent_Identity=24.8730964467005, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=25.6916996047431, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17565030, Length=197, Percent_Identity=26.9035532994924, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI193204405, Length=274, Percent_Identity=25.5474452554745, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=215, Percent_Identity=33.4883720930233, Blast_Score=102, Evalue=7e-23, Organism=Saccharomyces cerevisiae, GI6324126, Length=262, Percent_Identity=26.3358778625954, Blast_Score=72, Evalue=1e-13, Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=26.6331658291457, Blast_Score=66, Evalue=6e-12, Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=38.659793814433, Blast_Score=113, Evalue=1e-25, Organism=Drosophila melanogaster, GI24639444, Length=257, Percent_Identity=29.9610894941634, Blast_Score=104, Evalue=5e-23, Organism=Drosophila melanogaster, GI23397609, Length=262, Percent_Identity=32.0610687022901, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI17737361, Length=213, Percent_Identity=29.5774647887324, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI21357673, Length=275, Percent_Identity=29.8181818181818, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI21355319, Length=260, Percent_Identity=24.6153846153846, Blast_Score=84, Evalue=7e-17, Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=29.6153846153846, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24640492, Length=191, Percent_Identity=29.3193717277487, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI21358495, Length=195, Percent_Identity=24.6153846153846, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=28.3524904214559, Blast_Score=74, Evalue=7e-14, Organism=Drosophila melanogaster, GI24641232, Length=225, Percent_Identity=26.2222222222222, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24648944, Length=232, Percent_Identity=27.5862068965517, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI221331218, Length=196, Percent_Identity=27.5510204081633, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24665243, Length=194, Percent_Identity=27.8350515463918, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI28571526, Length=258, Percent_Identity=29.0697674418605, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665247, Length=195, Percent_Identity=28.2051282051282, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI221331216, Length=197, Percent_Identity=27.9187817258883, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21356301, Length=233, Percent_Identity=24.4635193133047, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI24649181, Length=189, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI28571387, Length=226, Percent_Identity=23.8938053097345, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI24581726, Length=196, Percent_Identity=26.0204081632653, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011294 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.30 [H]
Molecular weight: Translated: 27601; Mature: 27601
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 4.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 4.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKLKNKVAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVA CCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEE MNVTDEAQVNQGVDKVADHFGGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLT EECCCHHHHHCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCHHHH TKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKHGLLGLCKVVAKEGGTHKVRA HHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEE NVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS EEECCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH FESNALTGQSLVVSHGWFME CCCCCCCCCEEEEECCCCCC >Mature Secondary Structure MKLKNKVAIVTGAASGIGKEIALVYAKEGAKVAIADLNLDQASHVAEEIKSSGGQAMAVA CCCCCEEEEEEECCCCCCCEEEEEEECCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEE MNVTDEAQVNQGVDKVADHFGGVDVLVSNAGIQIIESVDKLAFSDWKRMLAIHLDGAFLT EECCCHHHHHCCHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHEEEEEECCHHHH TKACLKYMYASGNGGSIIYMGSVHSKEASVLKAPYVTAKHGLLGLCKVVAKEGGTHKVRA HHHHHHHHHCCCCCCEEEEECCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEE NVICPGFVRTPLVDKQIPEQAKELGISEEDVIKKVMLKETVDGEFTTTDDVAQTALFFAS EEECCCHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHH FESNALTGQSLVVSHGWFME CCCCCCCCCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9922248; 11481431 [H]