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The map label for this gene is pgsA

Identifier: 52842503

GI number: 52842503

Start: 2591078

End: 2591641

Strand: Reverse

Name: pgsA

Synonym: lpg2293

Alternate gene names: 52842503

Gene position: 2591641-2591078 (Counterclockwise)

Preceding gene: 52842504

Following gene: 52842502

Centisome position: 76.28

GC content: 39.36

Gene sequence:

>564_bases
GTGAGTACGTTAACCAGTTTGCCTAATATATTAACCTTAATGCGGATTTCGATCATTCCAGTATTTATTATGGTATTTTA
TTTTCCTTTCAAATGGGCTCATCCTACCGCTGCGGTTCTTTTTGCTATTGCAAGCATTACTGATTGGTTAGACGGTTATT
TGGCGCGCAAACTTGAAATGATGTCTCATTTTGGAGCTTTTCTTGATCCCGTCGCCGATAAATTATTGGTATCGACAAGC
TTGTTATTGTTAGTTGGAGCGAAAGATATAGATTATATCACTATACCTGCAATCGTAATCGTTGGACGAGAAATCGTGAT
TTCAGCTTTGCGCGAGTGGATGGCTGAAGTTGGACGTCGTGCTAGTGTTGCCGTTGGGTATATAGGGAAAGTTAAAACTT
CTTTGCAAATGATCGCTTTGGTATTATTGCTGGCATTTAATCCCCTTGTTTCTTGGTGGGGGAGCTTAGGGTTTGTTCTT
CTTTATGTGTCTGCTATTTTGACGATTTGGTCCATGGTGATTTATTTGGCTATTGCTTGGCCAGAGTTAATGAAAAAAAG
TTAA

Upstream 100 bases:

>100_bases
GCGCTTAAGGCAGCAGGTGCTTTGGCTGTATTTGATGATTATAAGCTATTGTCAGCTTATCTGATGTTGCCGGAAGCATA
AAAAAGGGGGATGTTCAGCA

Downstream 100 bases:

>100_bases
TTTTGCTGTTGACAGGGTATTTATTTTCGGTAGAATCTCATCCCGTAGAGACGCGGGAATAGCTCAGTTGGTAGAGCATA
ACCTTGCCAAGGTTAGGGTC

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSTLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEMMSHFGAFLDPVADKLLVSTS
LLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGRRASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFVL
LYVSAILTIWSMVIYLAIAWPELMKKS

Sequences:

>Translated_187_residues
MSTLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEMMSHFGAFLDPVADKLLVSTS
LLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGRRASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFVL
LYVSAILTIWSMVIYLAIAWPELMKKS
>Mature_186_residues
STLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEMMSHFGAFLDPVADKLLVSTSL
LLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGRRASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFVLL
YVSAILTIWSMVIYLAIAWPELMKKS

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=181, Percent_Identity=48.6187845303867, Blast_Score=178, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6320059, Length=133, Percent_Identity=39.8496240601504, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20808; Mature: 20677

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MSHFGAFLDPVADKLLVSTSLLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGRR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFVLLYVSAILTIWSMVIYLAIAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PELMKKS
HHHHCCC
>Mature Secondary Structure 
STLTSLPNILTLMRISIIPVFIMVFYFPFKWAHPTAAVLFAIASITDWLDGYLARKLEM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MSHFGAFLDPVADKLLVSTSLLLLVGAKDIDYITIPAIVIVGREIVISALREWMAEVGRR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
ASVAVGYIGKVKTSLQMIALVLLLAFNPLVSWWGSLGFVLLYVSAILTIWSMVIYLAIAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PELMKKS
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA