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The map label for this gene is ribA [H]

Identifier: 52842454

GI number: 52842454

Start: 2538893

End: 2540185

Strand: Direct

Name: ribA [H]

Synonym: lpg2241

Alternate gene names: 52842454

Gene position: 2538893-2540185 (Clockwise)

Preceding gene: 52842453

Following gene: 52842455

Centisome position: 74.72

GC content: 44.47

Gene sequence:

>1293_bases
TTGAAACAAAAGGAATTAAGTATCATGTCACCAGATGATTCAAAGAAAAAATCAAAAGGACACATTGTCTTGTCTTCACA
CCCGGCAAGCCACACACAAGCTCCATTAAAAATCAAATGGGGTGAAAAAAACCCTAAAGAGAGGGGGCCTGTTATTGCTT
CTCTCACTAATATCAAAAATCGAAATGCAGTTGGAACTCACTCAGGGTCTTACTCTGTTTACAGGGCCTTGGCAGTAGCA
GCTGGTCTGCTGGATCCCGAACACGTTCCTGATCTGACCGATACCCTGCCTCCTGTTGACATAGGGCCTCATAAGCAATG
GGGTGAAGCAGGCAAAATTGTCTCCCTCGATCCCTGGGGGCATCTAGTGGCTTCTGTTTTCTCAGAAGAAATAAAAGCCG
GCTATGACATCAGACCAACCATTGCCGTCACAAGGGCACATATTAATATCCCGGAATTGCATATTGCCATGCAAAAAGGC
AGATTAAAACCTGATGGAAAAATTTTAAGTGAAACAGGGGATGTCGTGGTGACTAAGGCCGCGATTGAACCAGTCTGGTA
CTTGCCTGGAATTGCGGAGCGCTTCCAGGTTTCAGAAGCATTGCTCAGACGCACTCTTTTTGAACAAACCGCTGGAATGT
TCCCTGAACTGGTGACCCGTAGCGACTTGGATGTCTTTTTGCCGCCCATTGGAGGATTAACTGCTTATTTCTTTGGTGAT
GTGACTACCATCCATAATCCGGAAATCGAATTAACTTGCCGTATCCATGATGAATGTAATGGCTCCGATGTCTTTGGTTC
TGACATATGCACTTGCAGACCATATTTGGTCCATGGAATCGAATTATCCATCGAATCCGCACAAAAAGGAGGCGCAGGCC
TTATCGTTTATAATCGCAAAGAAGGAAGAGCTCTTGGGGAGGTCACTAAATTTCTGGTTTATAACGCCAGAAAAAGACAG
AAAGGTGGTGACACTGCAGCCAAGTACTTTGAAAGAACGGAATGCGTTGCCGGTGTTCAGGATATGCGTTTCCAGGAATT
AATGTCCGATATTCTTCATTGGCTGGGGATCACTAAAATTCATCGCTTCGTTTCAATGTCCAATATGAAATACGATGCCT
TGCTCAAATCTGGAATCAATGTTATTGAACGGGTAAAAATACCGGATGAGTTGATTCCTCCAGATGCCCGGGTAGAAATA
GATGCCAAGCGTGCAGCAGGATATTACTCACCCGAAGGAATTATTGATATCAACGAATTGGCTAAACCGAAAGGACGTGC
CCTTCATGAATAA

Upstream 100 bases:

>100_bases
TCCAATGCTGTGGTTTATGATTGGTTAGACAGTTTATAACAACAGTGTGCACCTGCTTATAAAAGATAAAAGATAAAACA
ACCGATTTATTTGAGCACCG

Downstream 100 bases:

>100_bases
TCAAGAGCAGCAAATACAAAATGTTTTGAATACGCTTCGTGATCCTGACACCATAAGAACCCGGTCGCATCGTATTTTAA
ACTTGGCAAAACAAAATCGG

Product: hypothetical protein

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKQKELSIMSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHSGSYSVYRALAVA
AGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKG
RLKPDGKILSETGDVVVTKAAIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGD
VTTIHNPEIELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEVTKFLVYNARKRQ
KGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEI
DAKRAAGYYSPEGIIDINELAKPKGRALHE

Sequences:

>Translated_430_residues
MKQKELSIMSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHSGSYSVYRALAVA
AGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKG
RLKPDGKILSETGDVVVTKAAIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGD
VTTIHNPEIELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEVTKFLVYNARKRQ
KGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEI
DAKRAAGYYSPEGIIDINELAKPKGRALHE
>Mature_430_residues
MKQKELSIMSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHSGSYSVYRALAVA
AGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKG
RLKPDGKILSETGDVVVTKAAIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGD
VTTIHNPEIELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEVTKFLVYNARKRQ
KGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEI
DAKRAAGYYSPEGIIDINELAKPKGRALHE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 47482; Mature: 47482

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQKELSIMSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKN
CCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHHHCCEEEEECCCCC
RNAVGTHSGSYSVYRALAVAAGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCHH
HLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKILSETGDVVVTKA
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHEEEHHCCCCCCCCCEECCCCCEEEEEH
AIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGD
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCHHHHHHCC
VTTIHNPEIELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRK
EEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHEEEEEEEECCCCCCCEEEEEECC
EGRALGEVTKFLVYNARKRQKGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKI
CCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
HRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGYYSPEGIIDINEL
HHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEHHHCCCCCCCCCCEEHHHH
AKPKGRALHE
CCCCCCCCCC
>Mature Secondary Structure
MKQKELSIMSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKN
CCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHHHCCEEEEECCCCC
RNAVGTHSGSYSVYRALAVAAGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWG
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCHH
HLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKILSETGDVVVTKA
HHHHHHHHHHHHCCCCCCCEEEEEEEECCCCHHEEEHHCCCCCCCCCEECCCCCEEEEEH
AIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGD
HCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCHHHHHHCC
VTTIHNPEIELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRK
EEEEECCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHEEEEEEEECCCCCCCEEEEEECC
EGRALGEVTKFLVYNARKRQKGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKI
CCCHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
HRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGYYSPEGIIDINEL
HHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEHHHCCCCCCCCCCEEHHHH
AKPKGRALHE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA