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The map label for this gene is bepF [H]

Identifier: 52842390

GI number: 52842390

Start: 2442757

End: 2443863

Strand: Direct

Name: bepF [H]

Synonym: lpg2177

Alternate gene names: 52842390

Gene position: 2442757-2443863 (Clockwise)

Preceding gene: 52842388

Following gene: 52842391

Centisome position: 71.89

GC content: 40.2

Gene sequence:

>1107_bases
ATGAAAAAAAAACTGGCATTGGTCATGCGATTACTGGCTGTTATTCTTATTCCTGTCCTCATGTCCTGTAATTCAGAATC
CAATAAGCCAGTGGTACATACCTTGGCAGAAGTTGACGTCGCGCTACCAGTAAAAAAGAATATTGTAGAATGGGACGAAT
ACACAGGACGATTTCAAGCAGTAGAAGAAGTGGATGTTCGTGCCCGTGTCACTGGATATCTTGAGGCGATCAAGTTCCAA
GACGGCCAAATGGTAAAAAAAGGAGACGTTTTATTCGTTATTGATCAACGCCCCTTCAAATATGCTCTGGCAAGAGCAGA
AGCTCAATACGCCTTAGCCAAAGCGCAATATGAACGTGCCATAAAACTTCAAAAAGAGAAATTTATTTCAGCTGAAGTGA
TAGATCAACGATTTCAAGACGTACAAGTTGCTGAAACCAGAGTACAGGAAGCAAAATTGAATCTCGAATTTACTGAGGTC
AAATCCCCCATCAGTGGCAAAATTAGTCGAGATTTTGTGAGTGCGGGTAATTTAATCCGCATGAACGACACAGTCTTGAC
TAAAGTAGTTTCTGTTGATCCCATTTATTTTTATTTTGAAACCAGTCAAAATGATTTGCTCAAATACATACGCCTCGATC
GCGCTGGAAAAAGACTCAGCTCCGAGAAAAAACCAACTCCAGTCTTAATTAAGTTACCTGATGAAAAGGATTACTTGCAT
CAAGGAACAGTGGATTTTTTAGATAATGTGATTGACTCAGGCACAGGAACTATCCTTGCCAGAGCACTTGTCCCTAATCC
TGATAACGTCATTTATCCTGGTCTTTTTGCACGTGTAAAATTAGTTGGAAGTGGGGAATATGAAGCAATTTTACTCCCCG
ATAAAGCAATCAATACGGATCAAGCCCGCAAATTTGTGTATGTGGTTGATAATGAAAATAAAGTGAAACGAGTGTATGTT
GAGTTAGGGCCACTGCGCGAAAGCGGGTTTTACATTATCCGAAGTGGATTGAAAGGGGATGAAAAAGTTATCATTCATGG
AATCCAACGTATTCATGGCCCAAACCAGGAAGTTAAGCCTGTGGTAATTGAGGTGACTGAAAATTAA

Upstream 100 bases:

>100_bases
ATATTCACGGCATTACGCATAATGCGTCTTTATAAGCTAAACTAAGCTTATCCACTGGATCATAACATACCAGTGACTTG
AATATCAGGGATAGATAACA

Downstream 100 bases:

>100_bases
ACCGGTTTTGTATTGGAATTATGGTCATTTGATATAATTTTAATACTGCACAAAGCATACAACGTTTTATGGTGGAGCCC
TCACGAAAAGGATTTTCTGG

Product: HlyD family secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKKKLALVMRLLAVILIPVLMSCNSESNKPVVHTLAEVDVALPVKKNIVEWDEYTGRFQAVEEVDVRARVTGYLEAIKFQ
DGQMVKKGDVLFVIDQRPFKYALARAEAQYALAKAQYERAIKLQKEKFISAEVIDQRFQDVQVAETRVQEAKLNLEFTEV
KSPISGKISRDFVSAGNLIRMNDTVLTKVVSVDPIYFYFETSQNDLLKYIRLDRAGKRLSSEKKPTPVLIKLPDEKDYLH
QGTVDFLDNVIDSGTGTILARALVPNPDNVIYPGLFARVKLVGSGEYEAILLPDKAINTDQARKFVYVVDNENKVKRVYV
ELGPLRESGFYIIRSGLKGDEKVIIHGIQRIHGPNQEVKPVVIEVTEN

Sequences:

>Translated_368_residues
MKKKLALVMRLLAVILIPVLMSCNSESNKPVVHTLAEVDVALPVKKNIVEWDEYTGRFQAVEEVDVRARVTGYLEAIKFQ
DGQMVKKGDVLFVIDQRPFKYALARAEAQYALAKAQYERAIKLQKEKFISAEVIDQRFQDVQVAETRVQEAKLNLEFTEV
KSPISGKISRDFVSAGNLIRMNDTVLTKVVSVDPIYFYFETSQNDLLKYIRLDRAGKRLSSEKKPTPVLIKLPDEKDYLH
QGTVDFLDNVIDSGTGTILARALVPNPDNVIYPGLFARVKLVGSGEYEAILLPDKAINTDQARKFVYVVDNENKVKRVYV
ELGPLRESGFYIIRSGLKGDEKVIIHGIQRIHGPNQEVKPVVIEVTEN
>Mature_368_residues
MKKKLALVMRLLAVILIPVLMSCNSESNKPVVHTLAEVDVALPVKKNIVEWDEYTGRFQAVEEVDVRARVTGYLEAIKFQ
DGQMVKKGDVLFVIDQRPFKYALARAEAQYALAKAQYERAIKLQKEKFISAEVIDQRFQDVQVAETRVQEAKLNLEFTEV
KSPISGKISRDFVSAGNLIRMNDTVLTKVVSVDPIYFYFETSQNDLLKYIRLDRAGKRLSSEKKPTPVLIKLPDEKDYLH
QGTVDFLDNVIDSGTGTILARALVPNPDNVIYPGLFARVKLVGSGEYEAILLPDKAINTDQARKFVYVVDNENKVKRVYV
ELGPLRESGFYIIRSGLKGDEKVIIHGIQRIHGPNQEVKPVVIEVTEN

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=336, Percent_Identity=31.25, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789929, Length=371, Percent_Identity=28.3018867924528, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1789665, Length=324, Percent_Identity=30.2469135802469, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786668, Length=382, Percent_Identity=29.0575916230367, Blast_Score=129, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41580; Mature: 41580

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKLALVMRLLAVILIPVLMSCNSESNKPVVHTLAEVDVALPVKKNIVEWDEYTGRFQA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHEECCCHHCCCCHHHHCCHHHH
VEEVDVRARVTGYLEAIKFQDGQMVKKGDVLFVIDQRPFKYALARAEAQYALAKAQYERA
HHHHHHHHHHHHHHHHEEECCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
IKLQKEKFISAEVIDQRFQDVQVAETRVQEAKLNLEFTEVKSPISGKISRDFVSAGNLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHCCCCCCCHHHHHHCCCCEEE
MNDTVLTKVVSVDPIYFYFETSQNDLLKYIRLDRAGKRLSSEKKPTPVLIKLPDEKDYLH
ECCHHHHHEEEECEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
QGTVDFLDNVIDSGTGTILARALVPNPDNVIYPGLFARVKLVGSGEYEAILLPDKAINTD
CCCHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCEEEEEEEECCCEEEEECCCCCCCCC
QARKFVYVVDNENKVKRVYVELGPLRESGFYIIRSGLKGDEKVIIHGIQRIHGPNQEVKP
CCCEEEEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCE
VVIEVTEN
EEEEEECC
>Mature Secondary Structure
MKKKLALVMRLLAVILIPVLMSCNSESNKPVVHTLAEVDVALPVKKNIVEWDEYTGRFQA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHHHHEECCCHHCCCCHHHHCCHHHH
VEEVDVRARVTGYLEAIKFQDGQMVKKGDVLFVIDQRPFKYALARAEAQYALAKAQYERA
HHHHHHHHHHHHHHHHEEECCCCEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
IKLQKEKFISAEVIDQRFQDVQVAETRVQEAKLNLEFTEVKSPISGKISRDFVSAGNLIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHCCCCCCCHHHHHHCCCCEEE
MNDTVLTKVVSVDPIYFYFETSQNDLLKYIRLDRAGKRLSSEKKPTPVLIKLPDEKDYLH
ECCHHHHHEEEECEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHH
QGTVDFLDNVIDSGTGTILARALVPNPDNVIYPGLFARVKLVGSGEYEAILLPDKAINTD
CCCHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCEEEEEEEECCCEEEEECCCCCCCCC
QARKFVYVVDNENKVKRVYVELGPLRESGFYIIRSGLKGDEKVIIHGIQRIHGPNQEVKP
CCCEEEEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCE
VVIEVTEN
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]