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The map label for this gene is tnpA [H]

Identifier: 52842334

GI number: 52842334

Start: 2365065

End: 2366483

Strand: Direct

Name: tnpA [H]

Synonym: lpg2120

Alternate gene names: 52842334

Gene position: 2365065-2366483 (Clockwise)

Preceding gene: 52842330

Following gene: 52842335

Centisome position: 69.61

GC content: 39.18

Gene sequence:

>1419_bases
ATGGATTTAGCAATTGAGGATTCTGCGGCATGGTCGGAAGCTATTTTTGGTTCAGTTGATTTAGGTGATAAACGCCTGAC
TCATCGGTTAGCACAGATAGGTAAACAACTAACATCCTTGCCTGGTGGTTCTCTTCCAGAAAGTTGTGAAGGACAGGATG
CACTCATAGAAGGGAGTTATCGGTTTTTACGCAATAAACGAGTTACTGCGAGTCAAATTGCAGAGGGTGGTTACCAAGTA
ACAAGCTGGTTATCTCAGCGAATCCCTACTCTTTTGGCGATTGAAGACACAACCACACTATCCTATACCCATCAAATAAA
AGAATCATTAGGTGATTTAGGCGGTCCTAAAGAAAAAAGCAATCGAGGATTTCATGTTCACACCACCATGCTCATGGATG
CAGAACAAGAGAAAACAATAGGATTAATAGCGCAAGAACGTTGGTGTCGAGATATCAAAGAAAGAGGCAAAAAAAATCAT
CGACGAGTAAGGTTGTATACAGAGAAAGAAAGTTATAAATGGGAAAAGAATACTCGAGAGTTAGAGCGTCGTCTGGGTTC
TAAAATGTCTGATGTGATTTCTGTTTGCGATAGGGAAGCCGATATTTTTGAATACATTCAGTATAAGTTAGATAATCATC
AACGTTTTATTGTTCGAGCGAGCCATAATCGAAAACTGGAAGGAAGTTATGGTTATTTATTTCAAATGTTACCTTCTGCA
ACAATTTTGGGTACTTATACAATTGCAATAGCTCAAAAAGCAAATAGAAAGAAACGCCAAGCGGCTCTTGAATTAAAAAC
AGCATCCGTTACTTTCTCACTACCAGAGCGAAGAGCCAAAGCACGGGAATTAAAGCCAATCACTTTAAATGTGGTTATCG
CAAAAGAGAAAAATCCATCTGAAAGCGATTGCCTTGAATGGGTTCTATTAACAACAGAAGCAACCACAACATTAGAGTGT
GCTCGAAAAATAACACGATATTATGAGATGAGATGGCGCATTGAGGATTTTCATAAAGCATGGAAATCGGGGGTTGGTGC
TGAAGAGCAGCGTATGCAATCAATTGAAAATTTAGAGAAAATGATTGTCATTCTCTCATTTGTAGCAATTCGATTACTCC
AATTAAAAGAGTATTTTGAATACCCGACTACTCTAGTTATCAATGATAGCAGTACTTCTTGCGATGAATTGCTCACTGAT
GCTAAATGGAAAGTCTTATGGAATAGTGTTGAAAGAAAATCATTACCTGAAAAAATACCTACTGCTGCTTGGGCTTATAA
AGCAATAGCCAAGTTGGGCGGTTGGACTGATTCCAAAAGAACTGGGAAAGCAGCTTGGTCTACTATCTGGAAAGGATGGT
TCCGATTACAGGAACGAGTAGAAGGGCTTAGGATAGCTAACGAGTTGATGGAGATGTGA

Upstream 100 bases:

>100_bases
TATGTCTCAATAAGGACATCTTTCCCAAATACCTGAATCTTCTACACATCTTGTCTATATCAAAGAAACATGATCAAATC
GCCTCATTTTGAGGTAATGT

Downstream 100 bases:

>100_bases
TCAAGAGACAGCTTTGTTGGGGTAGAGCCAATATCTTATTTGGGGTAGAGCCTTGACTTGTAGCCTTAAAGAATAGTATT
CTGATCCTAGCTAGAAAATG

Product: IS4 family transposase Tn5

Products: NA

Alternate protein names: Tnp [H]

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MDLAIEDSAAWSEAIFGSVDLGDKRLTHRLAQIGKQLTSLPGGSLPESCEGQDALIEGSYRFLRNKRVTASQIAEGGYQV
TSWLSQRIPTLLAIEDTTTLSYTHQIKESLGDLGGPKEKSNRGFHVHTTMLMDAEQEKTIGLIAQERWCRDIKERGKKNH
RRVRLYTEKESYKWEKNTRELERRLGSKMSDVISVCDREADIFEYIQYKLDNHQRFIVRASHNRKLEGSYGYLFQMLPSA
TILGTYTIAIAQKANRKKRQAALELKTASVTFSLPERRAKARELKPITLNVVIAKEKNPSESDCLEWVLLTTEATTTLEC
ARKITRYYEMRWRIEDFHKAWKSGVGAEEQRMQSIENLEKMIVILSFVAIRLLQLKEYFEYPTTLVINDSSTSCDELLTD
AKWKVLWNSVERKSLPEKIPTAAWAYKAIAKLGGWTDSKRTGKAAWSTIWKGWFRLQERVEGLRIANELMEM

Sequences:

>Translated_472_residues
MDLAIEDSAAWSEAIFGSVDLGDKRLTHRLAQIGKQLTSLPGGSLPESCEGQDALIEGSYRFLRNKRVTASQIAEGGYQV
TSWLSQRIPTLLAIEDTTTLSYTHQIKESLGDLGGPKEKSNRGFHVHTTMLMDAEQEKTIGLIAQERWCRDIKERGKKNH
RRVRLYTEKESYKWEKNTRELERRLGSKMSDVISVCDREADIFEYIQYKLDNHQRFIVRASHNRKLEGSYGYLFQMLPSA
TILGTYTIAIAQKANRKKRQAALELKTASVTFSLPERRAKARELKPITLNVVIAKEKNPSESDCLEWVLLTTEATTTLEC
ARKITRYYEMRWRIEDFHKAWKSGVGAEEQRMQSIENLEKMIVILSFVAIRLLQLKEYFEYPTTLVINDSSTSCDELLTD
AKWKVLWNSVERKSLPEKIPTAAWAYKAIAKLGGWTDSKRTGKAAWSTIWKGWFRLQERVEGLRIANELMEM
>Mature_472_residues
MDLAIEDSAAWSEAIFGSVDLGDKRLTHRLAQIGKQLTSLPGGSLPESCEGQDALIEGSYRFLRNKRVTASQIAEGGYQV
TSWLSQRIPTLLAIEDTTTLSYTHQIKESLGDLGGPKEKSNRGFHVHTTMLMDAEQEKTIGLIAQERWCRDIKERGKKNH
RRVRLYTEKESYKWEKNTRELERRLGSKMSDVISVCDREADIFEYIQYKLDNHQRFIVRASHNRKLEGSYGYLFQMLPSA
TILGTYTIAIAQKANRKKRQAALELKTASVTFSLPERRAKARELKPITLNVVIAKEKNPSESDCLEWVLLTTEATTTLEC
ARKITRYYEMRWRIEDFHKAWKSGVGAEEQRMQSIENLEKMIVILSFVAIRLLQLKEYFEYPTTLVINDSSTSCDELLTD
AKWKVLWNSVERKSLPEKIPTAAWAYKAIAKLGGWTDSKRTGKAAWSTIWKGWFRLQERVEGLRIANELMEM

Specific function: Mediates transposition of transposon Tn5 by a 'cut and paste' mechanism. First, the monomeric transposase binds the 19 bp inverted DNA repeats flanking the transposon. Then, dimerization of the DNA-bound transposase creates a synaptic DNA complex. After n

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transposase 11 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR002559
- InterPro:   IPR003201
- InterPro:   IPR014737
- InterPro:   IPR014736
- InterPro:   IPR014735 [H]

Pfam domain/function: PF01609 Transposase_11; PF02281 Transposase_Tn5 [H]

EC number: NA

Molecular weight: Translated: 54274; Mature: 54274

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLAIEDSAAWSEAIFGSVDLGDKRLTHRLAQIGKQLTSLPGGSLPESCEGQDALIEGSY
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
RFLRNKRVTASQIAEGGYQVTSWLSQRIPTLLAIEDTTTLSYTHQIKESLGDLGGPKEKS
HHHHCCCCCHHHHHCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
NRGFHVHTTMLMDAEQEKTIGLIAQERWCRDIKERGKKNHRRVRLYTEKESYKWEKNTRE
CCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHH
LERRLGSKMSDVISVCDREADIFEYIQYKLDNHQRFIVRASHNRKLEGSYGYLFQMLPSA
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCC
TILGTYTIAIAQKANRKKRQAALELKTASVTFSLPERRAKARELKPITLNVVIAKEKNPS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECHHHHHHHHCCCCEEEEEEEEECCCCC
ESDCLEWVLLTTEATTTLECARKITRYYEMRWRIEDFHKAWKSGVGAEEQRMQSIENLEK
HHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MIVILSFVAIRLLQLKEYFEYPTTLVINDSSTSCDELLTDAKWKVLWNSVERKSLPEKIP
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHCCHHHCC
TAAWAYKAIAKLGGWTDSKRTGKAAWSTIWKGWFRLQERVEGLRIANELMEM
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDLAIEDSAAWSEAIFGSVDLGDKRLTHRLAQIGKQLTSLPGGSLPESCEGQDALIEGSY
CCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
RFLRNKRVTASQIAEGGYQVTSWLSQRIPTLLAIEDTTTLSYTHQIKESLGDLGGPKEKS
HHHHCCCCCHHHHHCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCC
NRGFHVHTTMLMDAEQEKTIGLIAQERWCRDIKERGKKNHRRVRLYTEKESYKWEKNTRE
CCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHH
LERRLGSKMSDVISVCDREADIFEYIQYKLDNHQRFIVRASHNRKLEGSYGYLFQMLPSA
HHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHHHHHHHCCC
TILGTYTIAIAQKANRKKRQAALELKTASVTFSLPERRAKARELKPITLNVVIAKEKNPS
HHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECHHHHHHHHCCCCEEEEEEEEECCCCC
ESDCLEWVLLTTEATTTLECARKITRYYEMRWRIEDFHKAWKSGVGAEEQRMQSIENLEK
HHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
MIVILSFVAIRLLQLKEYFEYPTTLVINDSSTSCDELLTDAKWKVLWNSVERKSLPEKIP
HHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCHHHHHHHHHHHHCCHHHCC
TAAWAYKAIAKLGGWTDSKRTGKAAWSTIWKGWFRLQERVEGLRIANELMEM
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6260374; 6271452; 7867940; 6291786; 10884228; 12367522; 11896402 [H]